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	Author	Debora Gil; Antonio Esteban Lansaque; Sebastian Stefaniga; Mihail Gaianu; Carles Sanchez
	Title	Data Augmentation from Sketch			Type	Conference Article
	Year	2019	Publication	International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging	Abbreviated Journal
	Volume	11840	Issue		Pages	155-162
	Keywords	Data augmentation; cycleGANs; Multi-objective optimization
	Abstract	State of the art machine learning methods need huge amounts of data with unambiguous annotations for their training. In the context of medical imaging this is, in general, a very difficult task due to limited access to clinical data, the time required for manual annotations and variability across experts. Simulated data could serve for data augmentation provided that its appearance was comparable to the actual appearance of intra-operative acquisitions. Generative Adversarial Networks (GANs) are a powerful tool for artistic style transfer, but lack a criteria for selecting epochs ensuring also preservation of intra-operative content. We propose a multi-objective optimization strategy for a selection of cycleGAN epochs ensuring a mapping between virtual images and the intra-operative domain preserving anatomical content. Our approach has been applied to simulate intra-operative bronchoscopic videos and chest CT scans from virtual sketches generated using simple graphical primitives.
	Address	Shenzhen; China; October 2019
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CLIP
	Notes	IAM; 600.145; 601.337; 600.139; 600.145			Approved	no
	Call Number	Admin @ si @ GES2019			Serial	3359
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	Author	Esmitt Ramirez; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil
	Title	Image-Based Bronchial Anatomy Codification for Biopsy Guiding in Video Bronchoscopy			Type	Conference Article
	Year	2018	Publication	OR 2.0 Context-Aware Operating Theaters, Computer Assisted Robotic Endoscopy, Clinical Image-Based Procedures, and Skin Image Analysis	Abbreviated Journal
	Volume	11041	Issue		Pages
	Keywords	Biopsy guiding; Bronchoscopy; Lung biopsy; Intervention guiding; Airway codification
	Abstract	Bronchoscopy examinations allow biopsy of pulmonary nodules with minimum risk for the patient. Even for experienced bronchoscopists, it is difficult to guide the bronchoscope to most distal lesions and obtain an accurate diagnosis. This paper presents an image-based codification of the bronchial anatomy for bronchoscopy biopsy guiding. The 3D anatomy of each patient is codified as a binary tree with nodes representing bronchial levels and edges labeled using their position on images projecting the 3D anatomy from a set of branching points. The paths from the root to leaves provide a codification of navigation routes with spatially consistent labels according to the anatomy observes in video bronchoscopy explorations. We evaluate our labeling approach as a guiding system in terms of the number of bronchial levels correctly codified, also in the number of labels-based instructions correctly supplied, using generalized mixed models and computer-generated data. Results obtained for three independent observers prove the consistency and reproducibility of our guiding system. We trust that our codification based on viewer’s projection might be used as a foundation for the navigation process in Virtual Bronchoscopy systems.
	Address	Granada; September 2018
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	MICCAIW
	Notes	IAM; 600.096; 600.075; 601.323; 600.145			Approved	no
	Call Number	Admin @ si @ RSB2018b			Serial	3137
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	Author	Debora Gil; Oriol Ramos Terrades; Elisa Minchole; Carles Sanchez; Noelia Cubero de Frutos; Marta Diez-Ferrer; Rosa Maria Ortiz; Antoni Rosell
	Title	Classification of Confocal Endomicroscopy Patterns for Diagnosis of Lung Cancer			Type	Conference Article
	Year	2017	Publication	6th Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging	Abbreviated Journal
	Volume	10550	Issue		Pages	151-159
	Keywords
	Abstract	Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy. The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%. We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results.
	Address	Quebec; Canada; September 2017
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CLIP
	Notes	IAM; 600.096; 600.075; 600.145			Approved	no
	Call Number	Admin @ si @ GRM2017			Serial	2957
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	Author	Antoni Gurgui; Debora Gil; Enric Marti; Vicente Grau
	Title	Left-Ventricle Basal Region Constrained Parametric Mapping to Unitary Domain			Type	Conference Article
	Year	2016	Publication	7th International Workshop on Statistical Atlases & Computational Modelling of the Heart	Abbreviated Journal
	Volume	10124	Issue		Pages	163-171
	Keywords	Laplacian; Constrained maps; Parameterization; Basal ring
	Abstract	Due to its complex geometry, the basal ring is often omitted when putting different heart geometries into correspondence. In this paper, we present the first results on a new mapping of the left ventricle basal rings onto a normalized coordinate system using a fold-over free approach to the solution to the Laplacian. To guarantee correspondences between different basal rings, we imposed some internal constrained positions at anatomical landmarks in the normalized coordinate system. To prevent internal fold-overs, constraints are handled by cutting the volume into regions defined by anatomical features and mapping each piece of the volume separately. Initial results presented in this paper indicate that our method is able to handle internal constrains without introducing fold-overs and thus guarantees one-to-one mappings between different basal ring geometries.
	Address	Athens; October 2016
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	STACOM
	Notes	IAM;			Approved	no
	Call Number	Admin @ si @ GGM2016			Serial	2884
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	Author	Hanne Kause; Aura Hernandez-Sabate; Patricia Marquez; Andrea Fuster; Luc Florack; Hans van Assen; Debora Gil
	Title	Confidence Measures for Assessing the HARP Algorithm in Tagged Magnetic Resonance Imaging			Type	Book Chapter
	Year	2015	Publication	Statistical Atlases and Computational Models of the Heart. Revised selected papers of Imaging and Modelling Challenges 6th International Workshop, STACOM 2015, Held in Conjunction with MICCAI 2015	Abbreviated Journal
	Volume	9534	Issue		Pages	69-79
	Keywords
	Abstract	Cardiac deformation and changes therein have been linked to pathologies. Both can be extracted in detail from tagged Magnetic Resonance Imaging (tMRI) using harmonic phase (HARP) images. Although point tracking algorithms have shown to have high accuracies on HARP images, these vary with position. Detecting and discarding areas with unreliable results is crucial for use in clinical support systems. This paper assesses the capability of two confidence measures (CMs), based on energy and image structure, for detecting locations with reduced accuracy in motion tracking results. These CMs were tested on a database of simulated tMRI images containing the most common artifacts that may affect tracking accuracy. CM performance is assessed based on its capability for HARP tracking error bounding and compared in terms of significant differences detected using a multi comparison analysis of variance that takes into account the most influential factors on HARP tracking performance. Results showed that the CM based on image structure was better suited to detect unreliable optical flow vectors. In addition, it was shown that CMs can be used to detect optical flow vectors with large errors in order to improve the optical flow obtained with the HARP tracking algorithm.
	Address	Munich; Germany; January 2015
	Corporate Author				Thesis
	Publisher	Springer International Publishing	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-319-28711-9	Medium
	Area		Expedition		Conference	STACOM
	Notes	ADAS; IAM; 600.075; 600.076; 600.060; 601.145			Approved	no
	Call Number	Admin @ si @ KHM2015			Serial	2734
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	Author	Debora Gil; F. Javier Sanchez; Gloria Fernandez Esparrach; Jorge Bernal
	Title	3D Stable Spatio-temporal Polyp Localization in Colonoscopy Videos			Type	Book Chapter
	Year	2015	Publication	Computer-Assisted and Robotic Endoscopy. Revised selected papers of Second International Workshop, CARE 2015, Held in Conjunction with MICCAI 2015	Abbreviated Journal
	Volume	9515	Issue		Pages	140-152
	Keywords	Colonoscopy, Polyp Detection, Polyp Localization, Region Extraction, Watersheds
	Abstract	Computational intelligent systems could reduce polyp miss rate in colonoscopy for colon cancer diagnosis and, thus, increase the efficiency of the procedure. One of the main problems of existing polyp localization methods is a lack of spatio-temporal stability in their response. We propose to explore the response of a given polyp localization across temporal windows in order to select those image regions presenting the highest stable spatio-temporal response. Spatio-temporal stability is achieved by extracting 3D watershed regions on the temporal window. Stability in localization response is statistically determined by analysis of the variance of the output of the localization method inside each 3D region. We have explored the benefits of considering spatio-temporal stability in two different tasks: polyp localization and polyp detection. Experimental results indicate an average improvement of 21:5% in polyp localization and 43:78% in polyp detection.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CARE
	Notes	IAM; MV; 600.075			Approved	no
	Call Number	Admin @ si @ GSF2015			Serial	2733
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	Author	Carles Sanchez; Debora Gil; Jorge Bernal; F. Javier Sanchez; Marta Diez-Ferrer; Antoni Rosell
	Title	Navigation Path Retrieval from Videobronchoscopy using Bronchial Branches			Type	Conference Article
	Year	2016	Publication	19th International Conference on Medical Image Computing and Computer Assisted Intervention Workshops	Abbreviated Journal
	Volume	9401	Issue		Pages	62-70
	Keywords	Bronchoscopy navigation; Lumen center; Brochial branches; Navigation path; Videobronchoscopy
	Abstract	Bronchoscopy biopsy can be used to diagnose lung cancer without risking complications of other interventions like transthoracic needle aspiration. During bronchoscopy, the clinician has to navigate through the bronchial tree to the target lesion. A main drawback is the difficulty to check whether the exploration is following the correct path. The usual guidance using fluoroscopy implies repeated radiation of the clinician, while alternative systems (like electromagnetic navigation) require specific equipment that increases intervention costs. We propose to compute the navigated path using anatomical landmarks extracted from the sole analysis of videobronchoscopy images. Such landmarks allow matching the current exploration to the path previously planned on a CT to indicate clinician whether the planning is being correctly followed or not. We present a feasibility study of our landmark based CT-video matching using bronchoscopic videos simulated on a virtual bronchoscopy interactive interface.
	Address	Quebec; Canada; September 2016
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	MICCAIW
	Notes	IAM; MV; 600.060; 600.075			Approved	no
	Call Number	Admin @ si @ SGB2016			Serial	2885
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	Author	Sergio Vera; Debora Gil; Miguel Angel Gonzalez Ballester
	Title	Anatomical parameterization for volumetric meshing of the liver			Type	Conference Article
	Year	2014	Publication	SPIE – Medical Imaging	Abbreviated Journal
	Volume	9036	Issue		Pages
	Keywords	Coordinate System; Anatomy Modeling; Parameterization
	Abstract	A coordinate system describing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to specific anatomical landmarks, the coordinate system allows integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric coordinate systems over the surface of anatomical shapes, given their flexibility to set values at specific locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at sites of limited geometric diversity. In this paper we present a method for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the volume medial surface. We have applied the methodology to define a common reference system for the liver shape and functional anatomy. This reference system sets a solid base for creating anatomical models of the patient’s liver, and allows comparing livers from several patients in a common framework of reference.
	Address	Amsterdam; September 2014
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	SPIE-MI
	Notes	IAM; 600.075			Approved	no
	Call Number	Admin @ si @ VGG2014			Serial	2456
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	Author	Jorge Bernal; Debora Gil; Carles Sanchez; F. Javier Sanchez
	Title	Discarding Non Informative Regions for Efficient Colonoscopy Image Analysis			Type	Conference Article
	Year	2014	Publication	1st MICCAI Workshop on Computer-Assisted and Robotic Endoscopy	Abbreviated Journal
	Volume	8899	Issue		Pages	1-10
	Keywords	Image Segmentation; Polyps, Colonoscopy; Valley Information; Energy Maps
	Abstract	In this paper we present a novel polyp region segmentation method for colonoscopy videos. Our method uses valley information associated to polyp boundaries in order to provide an initial segmentation. This first segmentation is refined to eliminate boundary discontinuities caused by image artifacts or other elements of the scene. Experimental results over a publicly annotated database show that our method outperforms both general and specific segmentation methods by providing more accurate regions rich in polyp content. We also prove how image preprocessing is needed to improve final polyp region segmentation.
	Address	Boston; USA; September 2014
	Corporate Author				Thesis
	Publisher	Springer International Publishing	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-319-13409-3	Medium
	Area		Expedition		Conference	CARE
	Notes	MV; IAM; 600.044; 600.047; 600.060; 600.075			Approved	no
	Call Number	Admin @ si @ BGS2014b			Serial	2503
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	Author	Patricia Marquez; H. Kause; A. Fuster; Aura Hernandez-Sabate; L. Florack; Debora Gil; Hans van Assen
	Title	Factors Affecting Optical Flow Performance in Tagging Magnetic Resonance Imaging			Type	Conference Article
	Year	2014	Publication	17th International Conference on Medical Image Computing and Computer Assisted Intervention	Abbreviated Journal
	Volume	8896	Issue		Pages	231-238
	Keywords	Optical flow; Performance Evaluation; Synthetic Database; ANOVA; Tagging Magnetic Resonance Imaging
	Abstract	Changes in cardiac deformation patterns are correlated with cardiac pathologies. Deformation can be extracted from tagging Magnetic Resonance Imaging (tMRI) using Optical Flow (OF) techniques. For applications of OF in a clinical setting it is important to assess to what extent the performance of a particular OF method is stable across dierent clinical acquisition artifacts. This paper presents a statistical validation framework, based on ANOVA, to assess the motion and appearance factors that have the largest in uence on OF accuracy drop. In order to validate this framework, we created a database of simulated tMRI data including the most common artifacts of MRI and test three dierent OF methods, including HARP.
	Address	Boston; USA; September 2014
	Corporate Author				Thesis
	Publisher	Springer International Publishing	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-319-14677-5	Medium
	Area		Expedition		Conference	STACOM
	Notes	IAM; ADAS; 600.060; 601.145; 600.076; 600.075			Approved	no
	Call Number	Admin @ si @ MKF2014			Serial	2495
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	Author	Francesco Brughi; Debora Gil; Llorenç Badiella; Eva Jove Casabella; Oriol Ramos Terrades
	Title	Exploring the impact of inter-query variability on the performance of retrieval systems			Type	Conference Article
	Year	2014	Publication	11th International Conference on Image Analysis and Recognition	Abbreviated Journal
	Volume	8814	Issue		Pages	413–420
	Keywords
	Abstract	This paper introduces a framework for evaluating the performance of information retrieval systems. Current evaluation metrics provide an average score that does not consider performance variability across the query set. In this manner, conclusions lack of any statistical significance, yielding poor inference to cases outside the query set and possibly unfair comparisons. We propose to apply statistical methods in order to obtain a more informative measure for problems in which different query classes can be identified. In this context, we assess the performance variability on two levels: overall variability across the whole query set and specific query class-related variability. To this end, we estimate confidence bands for precision-recall curves, and we apply ANOVA in order to assess the significance of the performance across different query classes.
	Address	Algarve; Portugal; October 2014
	Corporate Author				Thesis
	Publisher	Springer International Publishing	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-319-11757-7	Medium
	Area		Expedition		Conference	ICIAR
	Notes	IAM; DAG; 600.060; 600.061; 600.077; 600.075			Approved	no
	Call Number	Admin @ si @ BGB2014			Serial	2559
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	Author	Carles Sanchez; Jorge Bernal; Debora Gil; F. Javier Sanchez
	Title	On-line lumen centre detection in gastrointestinal and respiratory endoscopy			Type	Conference Article
	Year	2013	Publication	Second International Workshop Clinical Image-Based Procedures	Abbreviated Journal
	Volume	8361	Issue		Pages	31-38
	Keywords	Lumen centre detection; Bronchoscopy; Colonoscopy
	Abstract	We present in this paper a novel lumen centre detection for gastrointestinal and respiratory endoscopic images. The proposed method is based on the appearance and geometry of the lumen, which we defined as the darkest image region which centre is a hub of image gradients. Experimental results validated on the first public annotated gastro-respiratory database prove the reliability of the method for a wide range of images (with precision over 95 %).
	Address	Nagoya; Japan; September 2013
	Corporate Author				Thesis
	Publisher	Springer International Publishing	Place of Publication		Editor	Erdt, Marius and Linguraru, Marius George and Oyarzun Laura, Cristina and Shekhar, Raj and Wesarg, Stefan and González Ballester, Miguel Angel and Drechsler, Klaus
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN	978-3-319-05665-4	Medium
	Area	800	Expedition		Conference	CLIP
	Notes	MV; IAM; 600.047; 600.044; 600.060			Approved	no
	Call Number	Admin @ si @ SBG2013			Serial	2302
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	Author	Debora Gil; Agnes Borras; Sergio Vera; Miguel Angel Gonzalez Ballester
	Title	A Validation Benchmark for Assessment of Medial Surface Quality for Medical Applications			Type	Conference Article
	Year	2013	Publication	9th International Conference on Computer Vision Systems	Abbreviated Journal
	Volume	7963	Issue		Pages	334-343
	Keywords	Medial Surfaces; Shape Representation; Medical Applications; Performance Evaluation
	Abstract	Confident use of medial surfaces in medical decision support systems requires evaluating their quality for detecting pathological deformations and describing anatomical volumes. Validation in the medical imaging field is a challenging task mainly due to the difficulties for getting consensual ground truth. In this paper we propose a validation benchmark for assessing medial surfaces in the context of medical applications. Our benchmark includes a home-made database of synthetic medial surfaces and volumes and specific scores for evaluating surface accuracy, its stability against volume deformations and its capabilities for accurate reconstruction of anatomical volumes.
	Address	Sant Petersburg; Russia; July 2013
	Corporate Author				Thesis
	Publisher	Springer Berlin Heidelberg	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-642-39401-0	Medium
	Area		Expedition		Conference	ICVS
	Notes	IAM; 600.044; 600.060			Approved	no
	Call Number	Admin @ si @ GBV2013			Serial	2300
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	Author	Patricia Marquez; Debora Gil; Aura Hernandez-Sabate; Daniel Kondermann
	Title	When Is A Confidence Measure Good Enough?			Type	Conference Article
	Year	2013	Publication	9th International Conference on Computer Vision Systems	Abbreviated Journal
	Volume	7963	Issue		Pages	344-353
	Keywords	Optical flow, confidence measure, performance evaluation
	Abstract	Confidence estimation has recently become a hot topic in image processing and computer vision.Yet, several definitions exist of the term “confidence” which are sometimes used interchangeably. This is a position paper, in which we aim to give an overview on existing definitions, thereby clarifying the meaning of the used terms to facilitate further research in this field. Based on these clarifications, we develop a theory to compare confidence measures with respect to their quality.
	Address	St Petersburg; Russia; July 2013
	Corporate Author				Thesis
	Publisher	Springer Link	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-642-39401-0	Medium
	Area		Expedition		Conference	ICVS
	Notes	IAM;ADAS; 600.044; 600.057; 600.060; 601.145			Approved	no
	Call Number	IAM @ iam @ MGH2013a			Serial	2218
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	Author	Ferran Poveda; Debora Gil;Enric Marti
	Title	Multi-resolution DT-MRI cardiac tractography			Type	Conference Article
	Year	2012	Publication	Statistical Atlases And Computational Models Of The Heart: Imaging and Modelling Challenges	Abbreviated Journal
	Volume	7746	Issue		Pages	270-277
	Keywords
	Abstract	Even using objective measures from DT-MRI no consensus about myocardial architecture has been achieved so far. Streamlining provides good reconstructions at low level of detail, but falls short to give global abstract interpretations. In this paper, we present a multi-resolution methodology that is able to produce simplified representations of cardiac architecture. Our approach produces a reduced set of tracts that are representative of the main geometric features of myocardial anatomical structure. Experiments show that fiber geometry is preserved along reductions, which validates the simplified model for interpretation of cardiac architecture.
	Address	Nice, France
	Corporate Author				Thesis
	Publisher	Springer Berlin Heidelberg	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-642-36960-5	Medium
	Area		Expedition		Conference	STACOM
	Notes	IAM			Approved	no
	Call Number	IAM @ iam @ PGM2012			Serial	1986
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