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	Author	Debora Gil; Oriol Ramos Terrades; Elisa Minchole; Carles Sanchez; Noelia Cubero de Frutos; Marta Diez-Ferrer; Rosa Maria Ortiz; Antoni Rosell
	Title	Classification of Confocal Endomicroscopy Patterns for Diagnosis of Lung Cancer			Type	Conference Article
	Year	2017	Publication	6th Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging	Abbreviated Journal
	Volume	10550	Issue		Pages	151-159
	Keywords
	Abstract	Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy. The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%. We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results.
	Address	Quebec; Canada; September 2017
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CLIP
	Notes	IAM; 600.096; 600.075; 600.145;DAG			Approved	no
	Call Number	Admin @ si @ GRM2017			Serial	2957
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