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Debora Gil, Oriol Rodriguez-Leon, Petia Radeva, & Aura Hernandez-Sabate. (2007). "Assessing Artery Motion Compensation in IVUS " In Computer Analysis Of Images And Patterns (Vol. 4673, pp. 213–220). Lecture Notes in Computer Science. Heidelberg: Springerlink.
Abstract: Cardiac dynamics suppression is a main issue for visual improvement and computation of tissue mechanical properties in IntraVascular UltraSound (IVUS). Although in recent times several motion compensation techniques have arisen, there is a lack of objective evaluation of motion reduction in in vivo pullbacks. We consider that the assessment protocol deserves special attention for the sake of a clinical applicability as reliable as possible. Our work focuses on defining a quality measure and a validation protocol assessing IVUS motion compensation. On the grounds of continuum mechanics laws we introduce a novel score measuring motion reduction in in vivo sequences. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases.
Keywords: validation standards; quality measures; IVUS motion compensation; conservation laws; Fourier development
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F.Guirado, Ana Ripoll, C.Roig, Aura Hernandez-Sabate, & Emilio Luque. (2006). "Exploiting Throughput for Pipeline Execution in Streaming Image Processing Applications " In UAB, E. N. W, & et al. (Eds.), Euro-Par 2006 Parallel Processing (Vol. 4128, pp. 1095–1105). Lecture Notes In Computer Science. Dresden, Germany (European Union): Springer-Verlag Berlin Heidelberg.
Abstract: There is a large range of image processing applications that act on an input sequence of image frames that are continuously received. Throughput is a key performance measure to be optimized when execu- ting them. In this paper we propose a new task replication methodology for optimizing throughput for an image processing application in the field of medicine. The results show that by applying the proposed methodo- logy we are able to achieve the desired throughput in all cases, in such a way that the input frames can be processed at any given rate.
Keywords: 12th International Euro–Par Conference
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Aura Hernandez-Sabate, Debora Gil, David Roche, Monica M. S. Matsumoto, & Sergio S. Furuie. (2011). "Inferring the Performance of Medical Imaging Algorithms " In Pedro Real, Daniel Diaz-Pernil, Helena Molina-Abril, Ainhoa Berciano, & Walter Kropatsch (Eds.), 14th International Conference on Computer Analysis of Images and Patterns (Vol. 6854, pp. 520–528). L. Berlin: Springer-Verlag Berlin Heidelberg.
Abstract: Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence.
Keywords: Validation, Statistical Inference, Medical Imaging Algorithms.
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Patricia Marquez, Debora Gil, & Aura Hernandez-Sabate. (2012). "Error Analysis for Lucas-Kanade Based Schemes " In 9th International Conference on Image Analysis and Recognition (Vol. 7324, pp. 184–191). Lecture Notes in Computer Science. Springer-Verlag Berlin Heidelberg.
Abstract: Optical flow is a valuable tool for motion analysis in medical imaging sequences. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in medical sequences. This paper presents an error analysis of Lucas-Kanade schemes in terms of intrinsic design errors and numerical stability of the algorithm. Our analysis provides a confidence measure that is naturally correlated to the accuracy of the flow field. Our experiments show the higher predictive value of our confidence measure compared to existing measures.
Keywords: Optical flow, Confidence measure, Lucas-Kanade, Cardiac Magnetic Resonance
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Patricia Marquez, Debora Gil, & Aura Hernandez-Sabate. (2012). "A Complete Confidence Framework for Optical Flow " In Rita Cucchiara V. M. Andrea Fusiello (Ed.), 12th European Conference on Computer Vision – Workshops and Demonstrations (Vol. 7584, pp. 124–133). Florence, Italy, October 7-13, 2012: Springer-Verlag.
Abstract: Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.
Keywords: Optical flow, confidence measures, sparsification plots, error prediction plots
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Patricia Marquez, Debora Gil, Aura Hernandez-Sabate, & Daniel Kondermann. (2013). "When Is A Confidence Measure Good Enough? " In 9th International Conference on Computer Vision Systems (Vol. 7963, pp. 344–353). Springer Link.
Abstract: Confidence estimation has recently become a hot topic in image processing and computer vision.Yet, several definitions exist of the term “confidence” which are sometimes used interchangeably. This is a position paper, in which we aim to give an overview on existing definitions,
thereby clarifying the meaning of the used terms to facilitate further research in this field. Based on these clarifications, we develop a theory to compare confidence measures with respect to their quality.
Keywords: Optical flow, confidence measure, performance evaluation
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Patricia Marquez, H. Kause, A. Fuster, Aura Hernandez-Sabate, L. Florack, Debora Gil, et al. (2014). "Factors Affecting Optical Flow Performance in Tagging Magnetic Resonance Imaging " In 17th International Conference on Medical Image Computing and Computer Assisted Intervention (Vol. 8896, pp. 231–238). Springer International Publishing.
Abstract: Changes in cardiac deformation patterns are correlated with cardiac pathologies. Deformation can be extracted from tagging Magnetic Resonance Imaging (tMRI) using Optical Flow (OF) techniques. For applications of OF in a clinical setting it is important to assess to what extent the performance of a particular OF method is stable across di erent clinical acquisition artifacts. This paper presents a statistical validation framework, based on ANOVA, to assess the motion and appearance factors that have the largest in uence on OF accuracy drop.
In order to validate this framework, we created a database of simulated tMRI data including the most common artifacts of MRI and test three di erent OF methods, including HARP.
Keywords: Optical flow; Performance Evaluation; Synthetic Database; ANOVA; Tagging Magnetic Resonance Imaging
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Hanne Kause, Aura Hernandez-Sabate, Patricia Marquez, Andrea Fuster, Luc Florack, Hans van Assen, et al. (2015). "Confidence Measures for Assessing the HARP Algorithm in Tagged Magnetic Resonance Imaging " In Statistical Atlases and Computational Models of the Heart. Revised selected papers of Imaging and Modelling Challenges 6th International Workshop, STACOM 2015, Held in Conjunction with MICCAI 2015 (Vol. 9534, pp. 69–79). Springer International Publishing.
Abstract: Cardiac deformation and changes therein have been linked to pathologies. Both can be extracted in detail from tagged Magnetic Resonance Imaging (tMRI) using harmonic phase (HARP) images. Although point tracking algorithms have shown to have high accuracies on HARP images, these vary with position. Detecting and discarding areas with unreliable results is crucial for use in clinical support systems. This paper assesses the capability of two confidence measures (CMs), based on energy and image structure, for detecting locations with reduced accuracy in motion tracking results. These CMs were tested on a database of simulated tMRI images containing the most common artifacts that may affect tracking accuracy. CM performance is assessed based on its capability for HARP tracking error bounding and compared in terms of significant differences detected using a multi comparison analysis of variance that takes into account the most influential factors on HARP tracking performance. Results showed that the CM based on image structure was better suited to detect unreliable optical flow vectors. In addition, it was shown that CMs can be used to detect optical flow vectors with large errors in order to improve the optical flow obtained with the HARP tracking algorithm.
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Debora Gil, Aura Hernandez-Sabate, Mireia Burnat, Steven Jansen, & Jordi Martinez-Vilalta. (2009). "Structure-Preserving Smoothing of Biomedical Images " In 13th International Conference on Computer Analysis of Images and Patterns (Vol. 5702, pp. 427–434). Springer Berlin Heidelberg.
Abstract: Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.
Keywords: non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography.
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Jaume Garcia, Debora Gil, & Aura Hernandez-Sabate. (2010). "Endowing Canonical Geometries to Cardiac Structures " In O. Camara, M. Pop, K. Rhode, M. Sermesant, N. Smith, & A. Young (Eds.), Statistical Atlases And Computational Models Of The Heart (Vol. 6364, pp. 124–133). Lecture Notes in Computer Science. Springer Berlin / Heidelberg.
Abstract: International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view.
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