Abstract: Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. Although the muscular architecture of the heart has been debated by countless researchers, the controversy is still alive. Diffusion Tensor MRI, DT-MRI, is a unique imaging technique for computational validation of the muscular structure of the heart. By the complex arrangement of myocites, existing techniques can not provide comprehensive descriptions of the global muscular architecture. In this paper we introduce a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and indicate a global helical organization

Abstract: Image based human detection is of paramount interest due to its potential applications in fields such as advanced driving assistance, surveillance and media analysis. However, even detecting non-occluded standing humans remains a challenge of intensive research. The most promising human detectors rely on classifiers developed in the discriminative paradigm, i.e., trained with labelled samples. However, labeling is a manual intensive step, especially in cases like human detection where it is necessary to provide at least bounding boxes framing the humans for training. To overcome such problem, some authors have proposed the use of a virtual world where the labels of the different objects are obtained automatically. This means that the human models (classifiers) are learnt using the appearance of rendered images, i.e., using realistic computer graphics. Later, these models are used for human detection in images of the real world. The results of this technique are surprisingly good. However, these are not always as good as the classical approach of training and testing with data coming from the same camera, or similar ones. Accordingly, in this paper we address the challenge of using a virtual world for gathering (while playing a videogame) a large amount of automatically labelled samples (virtual humans and background) and then training a classifier that performs equal, in real-world images, than the one obtained by equally training from manually labelled real-world samples. For doing that, we cast the problem as one of domain adaptation. In doing so, we assume that a small amount of manually labelled samples from real-world images is required. To collect these labelled samples we propose a non-standard active learning technique. Therefore, ultimately our human model is learnt by the combination of virtual and real world labelled samples (Fig. 1), which has not been done before. We present quantitative results showing that this approach is valid.

Abstract: Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. The MIOCARDIA project is a multidisciplinary project in cooperation with l'Hospital de la Santa Creu i de Sant Pau, Clinica la Creu Blanca and Barcelona Supercomputing Center. The ultimate goal of this project is defining a computational model of the myocardium. The model takes into account the deep interrelation between the anatomy and the mechanics of the heart. The paper explains the workflow of the MIOCARDIA project. It also introduces a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and provides evidences of a global helical organization.

Abstract: This document describes the implementation using the Insight Toolkit of an algorithm for detecting creases (ridges and valleys) in N-dimensional images, based on the Local Structure Tensor of the image. In addition to the filter used to calculate the creaseness image, a filter for the computation of the structure tensor is also included in this submission.

Abstract: HPF is a plugin for the computation of clinical scores under Osirix.
This manual provides a basic guide for experienced clinical staff. Chapter 1 provides the theoretical background in which this plugin is based.
Next, in chapter 2 we provide basic instructions for installing and uninstalling this plugin. chapter 3we shows a step-by-step scenario to compute clinical scores from tagged-MRI images with HPF. Finally, in chapter 4 we provide a quick guide for plugin developers

Abstract: Among the components of a pedestrian detector, its trained pedestrian classifier is crucial for achieving the desired performance. The initial task of the training process consists in collecting samples of pedestrians and background, which involves tiresome manual annotation of pedestrian bounding boxes (BBs). Thus, recent works have assessed the use of automatically collected samples from photo-realistic virtual worlds. However, learning from virtual-world samples and testing in real-world images may suffer the dataset shift problem. Accordingly, in this paper we assess an strategy to collect samples from the real world and retrain with them, thus avoiding the dataset shift, but in such a way that no BBs of real-world pedestrians have to be provided. In particular, we train a pedestrian classifier based on virtual-world samples (no human annotation required). Then, using such a classifier we collect pedestrian samples from real-world images by detection. After, a human oracle rejects the false detections efficiently (weak annotation). Finally, a new classifier is trained with the accepted detections. We show that this classifier is competitive with respect to the counterpart trained with samples collected by manually annotating hundreds of pedestrian BBs.

Abstract: Pedestrian detection is of paramount interest for many applications, e.g. Advanced Driver Assistance Systems, Intelligent Video Surveillance and Multimedia systems. Most promising pedestrian detectors rely on appearance-based classifiers trained with annotated data. However, the required annotation step represents an intensive and subjective task for humans, what makes worth to minimize their intervention in this process by using computational tools like realistic virtual worlds. The reason to use these kind of tools relies in the fact that they allow the automatic generation of precise and rich annotations of visual information. Nevertheless, the use of this kind of data comes with the following question: can a pedestrian appearance model learnt with virtual-world data work successfully for pedestrian detection in real-world scenarios?. To answer this question, we conduct different experiments that suggest a positive answer. However, the pedestrian classifiers trained with virtual-world data can suffer the so called dataset shift problem as real-world based classifiers does. Accordingly, we have designed different domain adaptation techniques to face this problem, all of them integrated in a same framework (V-AYLA). We have explored different methods to train a domain adapted pedestrian classifiers by collecting a few pedestrian samples from the target domain (real world) and combining them with many samples of the source domain (virtual world). The extensive experiments we present show that pedestrian detectors developed within the V-AYLA framework do achieve domain adaptation. Ideally, we would like to adapt our system without any human intervention. Therefore, as a first proof of concept we also propose an unsupervised domain adaptation technique that avoids human intervention during the adaptation process. To the best of our knowledge, this Thesis work is the first demonstrating adaptation of virtual and real worlds for developing an object detector. Last but not least, we also assessed a different strategy to avoid the dataset shift that consists in collecting real-world samples and retrain with them in such a way that no bounding boxes of real-world pedestrians have to be provided. We show that the generated classifier is competitive with respect to the counterpart trained with samples collected by manually annotating pedestrian bounding boxes. The results presented on this Thesis not only end with a proposal for adapting a virtual-world pedestrian detector to the real world, but also it goes further by pointing out a new methodology that would allow the system to adapt to different situations, which we hope will provide the foundations for future research in this unexplored area.