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	Author	Debora Gil; F. Javier Sanchez; Gloria Fernandez Esparrach; Jorge Bernal
	Title	3D Stable Spatio-temporal Polyp Localization in Colonoscopy Videos			Type	Book Chapter
	Year	2015	Publication	Computer-Assisted and Robotic Endoscopy. Revised selected papers of Second International Workshop, CARE 2015, Held in Conjunction with MICCAI 2015	Abbreviated Journal
	Volume	9515	Issue		Pages	140-152
	Keywords	Colonoscopy, Polyp Detection, Polyp Localization, Region Extraction, Watersheds
	Abstract	Computational intelligent systems could reduce polyp miss rate in colonoscopy for colon cancer diagnosis and, thus, increase the efficiency of the procedure. One of the main problems of existing polyp localization methods is a lack of spatio-temporal stability in their response. We propose to explore the response of a given polyp localization across temporal windows in order to select those image regions presenting the highest stable spatio-temporal response. Spatio-temporal stability is achieved by extracting 3D watershed regions on the temporal window. Stability in localization response is statistically determined by analysis of the variance of the output of the localization method inside each 3D region. We have explored the benefits of considering spatio-temporal stability in two different tasks: polyp localization and polyp detection. Experimental results indicate an average improvement of 21:5% in polyp localization and 43:78% in polyp detection.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CARE
	Notes	IAM; MV; 600.075			Approved	no
	Call Number	Admin @ si @ GSF2015			Serial	2733
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	Author	Juan Borrego-Carazo; Carles Sanchez; David Castells; Jordi Carrabina; Debora Gil
	Title	A benchmark for the evaluation of computational methods for bronchoscopic navigation			Type	Journal Article
	Year	2022	Publication	International Journal of Computer Assisted Radiology and Surgery	Abbreviated Journal	IJCARS
	Volume	17	Issue	1	Pages
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM			Approved	no
	Call Number	Admin @ si @ BSC2022			Serial	3832
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	Author	Patricia Marquez;Debora Gil;Aura Hernandez-Sabate
	Title	A Complete Confidence Framework for Optical Flow			Type	Conference Article
	Year	2012	Publication	12th European Conference on Computer Vision – Workshops and Demonstrations	Abbreviated Journal
	Volume	7584	Issue	2	Pages	124-133
	Keywords	Optical flow, confidence measures, sparsification plots, error prediction plots
	Abstract	Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.
	Address
	Corporate Author				Thesis
	Publisher	Springer-Verlag	Place of Publication	Florence, Italy, October 7-13, 2012	Editor	Andrea Fusiello, Vittorio Murino ,Rita Cucchiara
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN		ISBN	978-3-642-33867-0	Medium
	Area		Expedition		Conference	ECCVW
	Notes	IAM;ADAS;			Approved	no
	Call Number	IAM @ iam @ MGH2012b			Serial	1991
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	Author	Patricia Marquez; Debora Gil; Aura Hernandez-Sabate
	Title	A Confidence Measure for Assessing Optical Flow Accuracy in the Absence of Ground Truth			Type	Conference Article
	Year	2011	Publication	IEEE International Conference on Computer Vision – Workshops	Abbreviated Journal
	Volume		Issue		Pages	2042-2049
	Keywords	IEEE International Conference on Computer Vision – Workshops
	Abstract	Optical flow is a valuable tool for motion analysis in autonomous navigation systems. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in real world sequences. This paper introduces a measure of optical flow accuracy for Lucas-Kanade based flows in terms of the numerical stability of the data-term. We call this measure optical flow condition number. A statistical analysis over ground-truth data show a good statistical correlation between the condition number and optical flow error. Experiments on driving sequences illustrate its potential for autonomous navigation systems.
	Address
	Corporate Author				Thesis
	Publisher	IEEE	Place of Publication	Barcelona (Spain)	Editor
	Language	English	Summary Language	English	Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	ICCVW
	Notes	IAM; ADAS			Approved	no
	Call Number	IAM @ iam @ MGH2011			Serial	1682
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	Author	Marta Ligero; Alonso Garcia Ruiz; Cristina Viaplana; Guillermo Villacampa; Maria V Raciti; Jaid Landa; Ignacio Matos; Juan Martin Liberal; Maria Ochoa de Olza; Cinta Hierro; Joaquin Mateo; Macarena Gonzalez; Rafael Morales Barrera; Cristina Suarez; Jordi Rodon; Elena Elez; Irene Braña; Eva Muñoz-Couselo; Ana Oaknin; Roberta Fasani; Paolo Nuciforo; Debora Gil; Carlota Rubio Perez; Joan Seoane; Enriqueta Felip; Manuel Escobar; Josep Tabernero; Joan Carles; Rodrigo Dienstmann; Elena Garralda; Raquel Perez Lopez
	Title	A CT-based radiomics signature is associated with response to immune checkpoint inhibitors in advanced solid tumors			Type	Journal Article
	Year	2021	Publication	Radiology	Abbreviated Journal
	Volume	299	Issue	1	Pages	109-119
	Keywords
	Abstract	Background Reliable predictive imaging markers of response to immune checkpoint inhibitors are needed. Purpose To develop and validate a pretreatment CT-based radiomics signature to predict response to immune checkpoint inhibitors in advanced solid tumors. Materials and Methods In this retrospective study, a radiomics signature was developed in patients with advanced solid tumors (including breast, cervix, gastrointestinal) treated with anti-programmed cell death-1 or programmed cell death ligand-1 monotherapy from August 2012 to May 2018 (cohort 1). This was tested in patients with bladder and lung cancer (cohorts 2 and 3). Radiomics variables were extracted from all metastases delineated at pretreatment CT and selected by using an elastic-net model. A regression model combined radiomics and clinical variables with response as the end point. Biologic validation of the radiomics score with RNA profiling of cytotoxic cells (cohort 4) was assessed with Mann-Whitney analysis. Results The radiomics signature was developed in 85 patients (cohort 1: mean age, 58 years ± 13 [standard deviation]; 43 men) and tested on 46 patients (cohort 2: mean age, 70 years ± 12; 37 men) and 47 patients (cohort 3: mean age, 64 years ± 11; 40 men). Biologic validation was performed in a further cohort of 20 patients (cohort 4: mean age, 60 years ± 13; 14 men). The radiomics signature was associated with clinical response to immune checkpoint inhibitors (area under the curve [AUC], 0.70; 95% CI: 0.64, 0.77; P < .001). In cohorts 2 and 3, the AUC was 0.67 (95% CI: 0.58, 0.76) and 0.67 (95% CI: 0.56, 0.77; P < .001), respectively. A radiomics-clinical signature (including baseline albumin level and lymphocyte count) improved on radiomics-only performance (AUC, 0.74 [95% CI: 0.63, 0.84; P < .001]; Akaike information criterion, 107.00 and 109.90, respectively). Conclusion A pretreatment CT-based radiomics signature is associated with response to immune checkpoint inhibitors, likely reflecting the tumor immunophenotype. © RSNA, 2021 Online supplemental material is available for this article. See also the editorial by Summers in this issue.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; 600.145			Approved	no
	Call Number	Admin @ si @ LGV2021			Serial	3593
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	Author	Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva
	Title	A Deterministic-Statistic Adventitia Detection in IVUS Images			Type	Conference Article
	Year	2005	Publication	ESC Congress	Abbreviated Journal
	Volume		Issue		Pages
	Keywords	Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation
	Abstract	Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.
	Address	Stockholm; Sweden; September 2005
	Corporate Author				Thesis
	Publisher		Place of Publication	,Sweden (EU)	Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	ESC
	Notes	IAM;MILAB			Approved	no
	Call Number	IAM @ iam @ RMF2005a			Serial	1523
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	Author	Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva
	Title	A Deterministic-Statistic Adventitia Detection in IVUS Images			Type	Conference Article
	Year	2005	Publication	3rd International workshop on International Workshop on Functional Imaging and Modeling of the Heart	Abbreviated Journal
	Volume		Issue		Pages	65-74
	Keywords	Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation
	Abstract	Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.
	Address	Barcelona; June 2005
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	FIMH
	Notes	IAM;MILAB			Approved	no
	Call Number	IAM @ iam @ RMF2005			Serial	1524
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	Author	Aura Hernandez-Sabate; Debora Gil; Petia Radeva
	Title	A Deterministic-Statistical Strategy for Adventitia Segmentation in IVUS images			Type	Report
	Year	2005	Publication	CVC Technical Report	Abbreviated Journal
	Volume		Issue	89	Pages
	Keywords
	Abstract	A useful tool for some specific studies in cardiac disease diagnosis is vessel plaque assessment by analysis of IVUS sequences. Manual detection of luminal (inner) and media-adventitia (external) vessel borders is the main activity of physicians in the process of lumen narrowing (plaque) quantification. Difficult definition of vessel border descriptors, as well as, shades, artifacts and blurred signal response due to ultrasound physical properties troubles automated adventitia segmentation. In order to efficiently approach such a complex problem, we propose blending advanced anisotropic filtering operators and statistical classification techniques into a vessel border modelling strategy. Our systematic statistical analysis shows that the reported adventitia detection achieves an accuracy in the range of inter-observer variability regardless of plaque nature, vessel geometry and incomplete vessel borders.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; MILAB			Approved	no
	Call Number	IAM @ iam @ HGR2005a			Serial	1548
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	Author	Oriol Ramos Terrades; Albert Berenguel; Debora Gil
	Title	A flexible outlier detector based on a topology given by graph communities			Type	Miscellaneous
	Year	2020	Publication	Arxiv	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	Outlier, or anomaly, detection is essential for optimal performance of machine learning methods and statistical predictive models. It is not just a technical step in a data cleaning process but a key topic in many fields such as fraudulent document detection, in medical applications and assisted diagnosis systems or detecting security threats. In contrast to population-based methods, neighborhood based local approaches are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. However, a main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters. This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world data sets show that our approach overall outperforms, both, local and global strategies in multi and single view settings.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; DAG; 600.139; 600.145; 600.140; 600.121			Approved	no
	Call Number	Admin @ si @ RBG2020			Serial	3475
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	Author	Oriol Ramos Terrades; Albert Berenguel; Debora Gil
	Title	A Flexible Outlier Detector Based on a Topology Given by Graph Communities			Type	Journal Article
	Year	2022	Publication	Big Data Research	Abbreviated Journal	BDR
	Volume	29	Issue		Pages	100332
	Keywords	Classification algorithms; Detection algorithms; Description of feature space local structure; Graph communities; Machine learning algorithms; Outlier detectors
	Abstract	Outlier detection is essential for optimal performance of machine learning methods and statistical predictive models. Their detection is especially determinant in small sample size unbalanced problems, since in such settings outliers become highly influential and significantly bias models. This particular experimental settings are usual in medical applications, like diagnosis of rare pathologies, outcome of experimental personalized treatments or pandemic emergencies. In contrast to population-based methods, neighborhood based local approaches compute an outlier score from the neighbors of each sample, are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. A main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters, like the number of neighbors. This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world and synthetic data sets show that our approach outperforms, both, local and global strategies in multi and single view settings.
	Address	August 28, 2022
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	DAG; IAM; 600.140; 600.121; 600.139; 600.145; 600.159			Approved	no
	Call Number	Admin @ si @ RBG2022a			Serial	3718
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	Author	Mariano Vazquez; Ruth Aris; Guillaume Hozeaux; R.Aubry; P.Villar;Jaume Garcia ; Debora Gil; Francesc Carreras
	Title	A massively parallel computational electrophysiology model of the heart			Type	Journal Article
	Year	2011	Publication	International Journal for Numerical Methods in Biomedical Engineering	Abbreviated Journal	IJNMBE
	Volume	27	Issue		Pages	1911-1929
	Keywords	computational electrophysiology; parallelization; finite element methods
	Abstract	This paper presents a patient-sensitive simulation strategy capable of using the most efficient way the high-performance computational resources. The proposed strategy directly involves three different players: Computational Mechanics Scientists (CMS), Image Processing Scientists and Cardiologists, each one mastering its own expertise area within the project. This paper describes the general integrative scheme but focusing on the CMS side presents a massively parallel implementation of computational electrophysiology applied to cardiac tissue simulation. The paper covers different angles of the computational problem: equations, numerical issues, the algorithm and parallel implementation. The proposed methodology is illustrated with numerical simulations testing all the different possibilities, ranging from small domains up to very large ones. A key issue is the almost ideal scalability not only for large and complex problems but also for medium-size meshes. The explicit formulation is particularly well suited for solving this highly transient problems, with very short time-scale.
	Address	Swansea (UK)
	Corporate Author	John Wiley & Sons, Ltd.			Thesis
	Publisher	John Wiley & Sons, Ltd.	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM			Approved	no
	Call Number	IAM @ iam @ VAH2011			Serial	1198
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	Author	Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil
	Title	A medial map capturing the essential geometry of organs			Type	Conference Article
	Year	2012	Publication	ISBI Workshop on Open Source Medical Image Analysis software	Abbreviated Journal
	Volume		Issue		Pages	1691 - 1694
	Keywords	Medial Surface Representation, Volume Reconstruction,Geometry , Image reconstruction , Liver , Manifolds , Shape , Surface morphology , Surface reconstruction
	Abstract	Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Accurate computation of one pixel wide medial surfaces is mandatory. Those surfaces must represent faithfully the geometry of the volume. Although morphological methods produce excellent results in 2D, their complexity and quality drops across dimensions, due to a more complex description of pixel neighborhoods. This paper introduces a continuous operator for accurate and efficient computation of medial structures of arbitrary dimension. Our experiments show its higher performance for medical imaging applications in terms of simplicity of medial structures and capability for reconstructing the anatomical volume
	Address	Barcelona,Spain
	Corporate Author				Thesis
	Publisher	IEEE	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	1945-7928	ISBN	978-1-4577-1857-1	Medium
	Area		Expedition		Conference	ISBI
	Notes	IAM			Approved	no
	Call Number	IAM @ iam @ VGG2012a			Serial	1989
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	Author	Debora Gil; Guillermo Torres
	Title	A multi-shape loss function with adaptive class balancing for the segmentation of lung structures			Type	Conference Article
	Year	2020	Publication	34th International Congress and Exhibition on Computer Assisted Radiology & Surgery	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract
	Address	Virtual; June 2020
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CARS
	Notes	IAM; 600.139; 600.145			Approved	no
	Call Number	Admin @ si @ GiT2020			Serial	3472
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	Author	Guillermo Torres; Debora Gil
	Title	A multi-shape loss function with adaptive class balancing for the segmentation of lung structures			Type	Journal Article
	Year	2020	Publication	International Journal of Computer Assisted Radiology and Surgery	Abbreviated Journal	IJCAR
	Volume	15	Issue	1	Pages	S154-55
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM			Approved	no
	Call Number	Admin @ si @ ToG2020			Serial	3590
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	Author	A. M. Here; B. C. Lopez; Debora Gil; J. J. Camarero; Jordi Martinez-Vilalta
	Title	A new software to analyse wood anatomical features in conifer species			Type	Conference Article
	Year	2013	Publication	International Symposium on Wood Structure in Plant Biology and Ecology	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	International Symposium on Wood Structure in Plant Biology and Ecology
	Address	Naples; Italy; March 2013
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	WSE
	Notes	IAM			Approved	no
	Call Number	Admin @ si @ HLG2013			Serial	2303
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