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Author Albert Andaluz; Francesc Carreras; Cristina Santa Marta;Debora Gil edit   pdf
url  openurl
  Title Myocardial torsion estimation with Tagged-MRI in the OsiriX platform Type Conference Article
  Year (down) 2012 Publication ISBI Workshop on Open Source Medical Image Analysis software Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Myocardial torsion (MT) plays a crucial role in the assessment of the functionality of the
left ventricle. For this purpose, the IAM group at the CVC has developed the Harmonic Phase Flow (HPF) plugin for the Osirix DICOM platform . We have validated its funcionalty on sequences acquired using different protocols and including healthy and pathological cases. Results show similar torsion trends for SPAMM acquisitions, with pathological cases introducing expected deviations from the ground truth. Finally, we provide the plugin free of charge at http://iam.cvc.uab.es
 
  Address Barcelona, Spain  
  Corporate Author Thesis  
  Publisher IEEE Place of Publication Editor Wiro Niessen (Erasmus MC) and Marc Modat (UCL)  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference ISBI  
  Notes IAM Approved no  
  Call Number IAM @ iam @ ACS2012 Serial 1900  
Permanent link to this record
 

 
Author David Roche; Debora Gil; Jesus Giraldo edit   pdf
url  openurl
  Title Assessing agonist efficacy in an uncertain Em world Type Conference Article
  Year (down) 2012 Publication 40th Keystone Symposia on mollecular and celular biology Abbreviated Journal  
  Volume Issue Pages 79  
  Keywords  
  Abstract The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.
 
  Address Fairmont Banff Springs, Banff, Alberta, Canada  
  Corporate Author Keystone Symposia Thesis  
  Publisher Keystone Symposia Place of Publication Editor A. Christopoulus and M. Bouvier  
  Language english Summary Language english Original Title  
  Series Editor Keystone Symposia Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference KSMCB  
  Notes IAM Approved no  
  Call Number IAM @ iam @ RGG2012 Serial 1855  
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Author Debora Gil;Agnes Borras;Ruth Aris;Mariano Vazquez;Pierre Lafortune; Guillame Houzeaux edit   pdf
doi  isbn
openurl 
  Title What a difference in biomechanics cardiac fiber makes Type Conference Article
  Year (down) 2012 Publication Statistical Atlases And Computational Models Of The Heart: Imaging and Modelling Challenges Abbreviated Journal  
  Volume 7746 Issue Pages 253-260  
  Keywords  
  Abstract Computational simulations of the heart are a powerful tool for a comprehensive understanding of cardiac function and its intrinsic relationship with its muscular architecture. Cardiac biomechanical models require a vector field representing the orientation of cardiac fibers. A wrong orientation of the fibers can lead to a
non-realistic simulation of the heart functionality. In this paper we explore the impact of the fiber information on the simulated biomechanics of cardiac muscular anatomy. We have used the John Hopkins database to perform a biomechanical simulation using both a synthetic benchmark fiber distribution and the data obtained experimentally from DTI. Results illustrate how differences in fiber orientation affect heart deformation along cardiac cycle.
 
  Address Nice, France  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-36960-5 Medium  
  Area Expedition Conference STACOM  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GBA2012 Serial 1987  
Permanent link to this record
 

 
Author Ferran Poveda; Debora Gil;Enric Marti edit   pdf
doi  isbn
openurl 
  Title Multi-resolution DT-MRI cardiac tractography Type Conference Article
  Year (down) 2012 Publication Statistical Atlases And Computational Models Of The Heart: Imaging and Modelling Challenges Abbreviated Journal  
  Volume 7746 Issue Pages 270-277  
  Keywords  
  Abstract Even using objective measures from DT-MRI no consensus about myocardial architecture has been achieved so far. Streamlining provides good reconstructions at low level of detail, but falls short to give global abstract interpretations. In this paper, we present a multi-resolution methodology that is able to produce simplified representations of cardiac architecture. Our approach produces a reduced set of tracts that are representative of the main geometric features of myocardial anatomical structure. Experiments show that fiber geometry is preserved along reductions, which validates the simplified model for interpretation of cardiac architecture.  
  Address Nice, France  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-36960-5 Medium  
  Area Expedition Conference STACOM  
  Notes IAM Approved no  
  Call Number IAM @ iam @ PGM2012 Serial 1986  
Permanent link to this record
 

 
Author Patricia Marquez; Debora Gil ; Aura Hernandez-Sabate edit   pdf
doi  isbn
openurl 
  Title Error Analysis for Lucas-Kanade Based Schemes Type Conference Article
  Year (down) 2012 Publication 9th International Conference on Image Analysis and Recognition Abbreviated Journal  
  Volume 7324 Issue I Pages 184-191  
  Keywords Optical flow, Confidence measure, Lucas-Kanade, Cardiac Magnetic Resonance  
  Abstract Optical flow is a valuable tool for motion analysis in medical imaging sequences. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in medical sequences. This paper presents an error analysis of Lucas-Kanade schemes in terms of intrinsic design errors and numerical stability of the algorithm. Our analysis provides a confidence measure that is naturally correlated to the accuracy of the flow field. Our experiments show the higher predictive value of our confidence measure compared to existing measures.  
  Address Aveiro, Portugal  
  Corporate Author Thesis  
  Publisher Springer-Verlag Berlin Heidelberg Place of Publication Editor  
  Language english Summary Language Original Title  
  Series Editor Campilho, Aurélio and Kamel, Mohamed Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-31294-6 Medium  
  Area Expedition Conference ICIAR  
  Notes IAM Approved no  
  Call Number IAM @ iam @ MGH2012a Serial 1899  
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Author Patricia Marquez;Debora Gil;Aura Hernandez-Sabate edit   pdf
doi  isbn
openurl 
  Title A Complete Confidence Framework for Optical Flow Type Conference Article
  Year (down) 2012 Publication 12th European Conference on Computer Vision – Workshops and Demonstrations Abbreviated Journal  
  Volume 7584 Issue 2 Pages 124-133  
  Keywords Optical flow, confidence measures, sparsification plots, error prediction plots  
  Abstract Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.  
  Address  
  Corporate Author Thesis  
  Publisher Springer-Verlag Place of Publication Florence, Italy, October 7-13, 2012 Editor Andrea Fusiello, Vittorio Murino ,Rita Cucchiara  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-3-642-33867-0 Medium  
  Area Expedition Conference ECCVW  
  Notes IAM;ADAS; Approved no  
  Call Number IAM @ iam @ MGH2012b Serial 1991  
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Author Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil edit   pdf
doi  isbn
openurl 
  Title A medial map capturing the essential geometry of organs Type Conference Article
  Year (down) 2012 Publication ISBI Workshop on Open Source Medical Image Analysis software Abbreviated Journal  
  Volume Issue Pages 1691 - 1694  
  Keywords Medial Surface Representation, Volume Reconstruction,Geometry , Image reconstruction , Liver , Manifolds , Shape , Surface morphology , Surface reconstruction  
  Abstract Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Accurate computation of one pixel wide medial surfaces is mandatory. Those surfaces must represent faithfully the geometry of the volume. Although morphological methods produce excellent results in 2D, their complexity and quality drops across dimensions, due to a more complex description of pixel neighborhoods. This paper introduces a continuous operator for accurate and efficient computation of medial structures of arbitrary dimension. Our experiments show its higher performance for medical imaging applications in terms of simplicity of medial structures and capability for reconstructing the anatomical volume  
  Address Barcelona,Spain  
  Corporate Author Thesis  
  Publisher IEEE Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1945-7928 ISBN 978-1-4577-1857-1 Medium  
  Area Expedition Conference ISBI  
  Notes IAM Approved no  
  Call Number IAM @ iam @ VGG2012a Serial 1989  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil; David Roche; Monica M. S. Matsumoto; Sergio S. Furuie edit   pdf
url  openurl
  Title Inferring the Performance of Medical Imaging Algorithms Type Conference Article
  Year (down) 2011 Publication 14th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal  
  Volume 6854 Issue Pages 520-528  
  Keywords Validation, Statistical Inference, Medical Imaging Algorithms.  
  Abstract Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence.
 
  Address Sevilla  
  Corporate Author Thesis  
  Publisher Springer-Verlag Berlin Heidelberg Place of Publication Berlin Editor Pedro Real; Daniel Diaz-Pernil; Helena Molina-Abril; Ainhoa Berciano; Walter Kropatsch  
  Language Summary Language Original Title  
  Series Editor Series Title L Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CAIP  
  Notes IAM; ADAS Approved no  
  Call Number IAM @ iam @ HGR2011 Serial 1676  
Permanent link to this record
 

 
Author David Roche; Debora Gil; Jesus Giraldo edit   pdf
openurl 
  Title Using statistical inference for designing termination conditions ensuring convergence of Evolutionary Algorithms Type Conference Article
  Year (down) 2011 Publication 11th European Conference on Artificial Life Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract A main challenge in Evolutionary Algorithms (EAs) is determining a termination condition ensuring stabilization close to the optimum in real-world applications. Although for known test functions distribution-based quantities are good candidates (as far as suitable parameters are used), in real-world problems an open question still remains unsolved. How can we estimate an upper-bound for the termination condition value ensuring a given accuracy for the (unknown) EA solution?
We claim that the termination problem would be fully solved if we defined a quantity (depending only on the EA output) behaving like the solution accuracy. The open question would be, then, satisfactorily answered if we had a model relating both quantities, since accuracy could be predicted from the alternative quantity. We present a statistical inference framework addressing two topics: checking the correlation between the two quantities and defining a regression model for predicting (at a given confidence level) accuracy values from the EA output.
 
  Address Paris, France  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference ECAL  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ RGG2011b Serial 1678  
Permanent link to this record
 

 
Author David Roche; Debora Gil; Jesus Giraldo edit   pdf
url  isbn
openurl 
  Title An inference model for analyzing termination conditions of Evolutionary Algorithms Type Conference Article
  Year (down) 2011 Publication 14th Congrès Català en Intel·ligencia Artificial Abbreviated Journal  
  Volume Issue Pages 216-225  
  Keywords Evolutionary Computation Convergence, Termination Conditions, Statistical Inference  
  Abstract In real-world problems, it is mandatory to design a termination condition for Evolutionary Algorithms (EAs) ensuring stabilization close to the unknown optimum. Distribution-based quantities are good candidates as far as suitable parameters are used. A main limitation for application to real-world problems is that such parameters strongly depend on the topology of the objective function, as well as, the EA paradigm used.
We claim that the termination problem would be fully solved if we had a model measuring to what extent a distribution-based quantity asymptotically behaves like the solution accuracy. We present a regression-prediction model that relates any two given quantities and reports if they can be statistically swapped as termination conditions. Our framework is applied to two issues. First, exploring if the parameters involved in the computation of distribution-based quantities influence their asymptotic behavior. Second, to what extent existing distribution-based quantities can be asymptotically exchanged for the accuracy of the EA solution.
 
  Address Lleida, Catalonia (Spain)  
  Corporate Author Associació Catalana Intel·ligència Artificial Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-1-60750-841-0 Medium  
  Area Expedition Conference CCIA  
  Notes IAM Approved no  
  Call Number IAM @ iam @ RGG2011a Serial 1677  
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