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Author |
Debora Gil; Oriol Rodriguez; J. Mauri; Petia Radeva |
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Title |
Statistical descriptors of the Myocardial perfusion in angiographic images |
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2006 |
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Proc. Computers in Cardiology |
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677-680 |
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Anisotropic processing; intravascular ultrasound (IVUS); vessel border segmentation; vessel structure classification. |
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Restoration of coronary flow after primary percutaneous coronary intervention in acute myocardial infarction does not always correlate with adequate myocardial perfusion. Recently, coronary angiography has been used to assess microcirculation integrity (Myocardial BlushAnalysis, MBA). Although MBA correlates with patient prognosis there are few image processing methods addressing objective perfusion quantification. The goal of this work is to develop statistical descriptors of the myocardial dyeing pattern allowing objective assessment of myocardial perfusion. Experiments on healthy right coronary arteries show that our approach allows reliable measurements without any specific image acquisition protocol. |
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IAM @ iam @ GRR2006 |
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1528 |
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Author |
Debora Gil; Petia Radeva; J. Mauri |
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Title |
Ivus Segmentation Via a Regularized Curvature Flow |
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2002 |
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X Congreso Anual de la Sociedad Española de Ingeniería Biomédica CASEIB 2002 |
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133-136 |
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Cardiac diseases are diagnosed and treated through a study of the morphology and dynamics of cardiac arteries. In- travascular Ultrasound (IVUS) imaging is of high interest to physicians since it provides both information. At the current state-of-the-art in image segmentation, a robust detection of the arterial lumen in IVUS demands manual intervention or ECG-gating. Manual intervention is a tedious and time consuming task that requires experienced observers, meanwhile ECG-gating is an acquisition technique not available in all clinical centers. We introduce a parametric algorithm that detects the arterial luminal border in in vivo sequences. The method consist in smoothing the sequences’ level surfaces under a regularized mean curvature flow that admits non-trivial steady states. The flow is based on a measure of the surface local smoothness that takes into account regularity of the surface curvature. |
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Saragossa, Espanya |
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IAM;MILAB |
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IAM @ iam @ GRM2002 |
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1536 |
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Author |
Debora Gil; Petia Radeva; Jordi Saludes; J. Mauri |
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Title |
Automatic Segmentation of Artery Wall in Coronary IVUS Images: A Probabilistic Approach |
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2000 |
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International Conference on Pattern Recognition |
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4 |
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352-355 |
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Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results. |
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IAM;MILAB |
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IAM @ iam @ GRS2000a |
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1537 |
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Author |
Debora Gil; Petia Radeva; Jordi Saludes; J. Mauri |
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Title |
Automatic Segmentation of Artery Wall in Coronary IVUS Images: a Probabilistic Approach |
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Conference Article |
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2000 |
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Proceedings of CIC’2000 |
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Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results. |
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Cambridge, Massachussets |
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CIC |
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IAM;MILAB |
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IAM @ iam @ GRS2000 |
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1538 |
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Author |
Debora Gil; Petia Radeva; Fernando Vilariño |
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Title |
Anisotropic Contour Completion |
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2003 |
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Proceedings of the IEEE International Conference on Image Processing |
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I-869 |
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In this paper we introduce a novel application of the diffusion tensor for anisotropic image processing. The Anisotropic Contour Completion (ACC) we suggest consists in extending the characteristic function of the open curve by means of a degenerated diffusion tensor that prevents any diffusion in the normal direction. We show that ACC is equivalent to a dilation with a continuous elliptic structural element that takes into account the local orientation of the contours to be closed. Experiments on contours extracted from real images show that ACC produces shapes able to adapt to any curve in an active contour framework. 1. |
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Barcelona, Spain |
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Barcelona, Spain |
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0-7803-7751-6 |
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ICIP |
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IAM;MV;MILAB;SIAI |
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IAM @ iam @ GRV2003 |
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1539 |
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Author |
Aura Hernandez-Sabate; Debora Gil; Petia Radeva |
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Title |
On the usefulness of supervised learning for vessel border detection in IntraVascular Imaging |
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Conference Article |
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2005 |
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Proceeding of the 2005 conference on Artificial Intelligence Research and Development |
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67-74 |
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classification; vessel border modelling; IVUS |
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IntraVascular UltraSound (IVUS) imaging is a useful tool in diagnosis of cardiac diseases since sequences completely show the morphology of coronary vessels. Vessel borders detection, especially the external adventitia layer, plays a central role in morphological measures and, thus, their segmentation feeds development of medical imaging techniques. Deterministic approaches fail to yield optimal results due to the large amount of IVUS artifacts and vessel borders descriptors. We propose using classification techniques to learn the set of descriptors and parameters that best detect vessel borders. Statistical hypothesis test on the error between automated detections and manually traced borders by 4 experts show that our detections keep within inter-observer variability. |
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IOS Press |
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Amsterdam, The Netherlands |
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IAM;MILAB |
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IAM @ iam @ HGR2005c |
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1549 |
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Author |
Aura Hernandez-Sabate; Debora Gil; Albert Teis |
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Title |
How Do Conservation Laws Define a Motion Suppression Score in In-Vivo Ivus Sequences? |
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Conference Article |
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2007 |
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Proc. IEEE Ultrasonics Symp |
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2231-2234 |
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validation standards; IVUS motion compensation; conservation laws. |
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Evaluation of arterial tissue biomechanics for diagnosis and treatment of cardiovascular diseases is an active research field in the biomedical imaging processing area. IntraVascular UltraSound (IVUS) is a unique tool for such assessment since it reflects tissue morphology and deformation. A proper quantification and visualization of both properties is hindered by vessel structures misalignments introduced by cardiac dynamics. This has encouraged development of IVUS motion compensation techniques. However, there is a lack of an objective evaluation of motion reduction ensuring a reliable clinical application This work reports a novel score, the Conservation of Density Rate (CDR), for validation of motion compensation in in-vivo pullbacks. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases. |
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IAM |
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IAM @ iam @ HTG2007 |
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1550 |
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Author |
Aura Hernandez-Sabate; Monica Mitiko; Sergio Shiguemi; Debora Gil |
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A validation protocol for assessing cardiac phase retrieval in IntraVascular UltraSound |
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2010 |
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Computing in Cardiology |
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37 |
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899-902 |
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A good reliable approach to cardiac triggering is of utmost importance in obtaining accurate quantitative results of atherosclerotic plaque burden from the analysis of IntraVascular UltraSound. Although, in the last years, there has been an increase in research of methods for retrospective gating, there is no general consensus in a validation protocol. Many methods are based on quality assessment of longitudinal cuts appearance and those reporting quantitative numbers do not follow a standard protocol. Such heterogeneity in validation protocols makes faithful comparison across methods a difficult task. We propose a validation protocol based on the variability of the retrieved cardiac phase and explore the capability of several quality measures for quantifying such variability. An ideal detector, suitable for its application in clinical practice, should produce stable phases. That is, it should always sample the same cardiac cycle fraction. In this context, one should measure the variability (variance) of a candidate sampling with respect a ground truth (reference) sampling, since the variance would indicate how spread we are aiming a target. In order to quantify the deviation between the sampling and the ground truth, we have considered two quality scores reported in the literature: signed distance to the closest reference sample and distance to the right of each reference sample. We have also considered the residuals of the regression line of reference against candidate sampling. The performance of the measures has been explored on a set of synthetic samplings covering different cardiac cycle fractions and variabilities. From our simulations, we conclude that the metrics related to distances are sensitive to the shift considered while the residuals are robust against fraction and variabilities as far as one can establish a pair-wise correspondence between candidate and reference. We will further investigate the impact of false positive and negative detections in experimental data. |
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IEEE |
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0276-6547 |
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978-1-4244-7318-2 |
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CINC |
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IAM; |
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IAM @ iam @ HSM2010 |
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1551 |
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Author |
Aura Hernandez-Sabate; Petia Radeva; Antonio Tovar; Debora Gil |
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Vessel structures alignment by spectral analysis of ivus sequences |
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2006 |
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Proc. of CVII, MICCAI Workshop |
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39-36 |
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Three-dimensional intravascular ultrasound (IVUS) allows to visualize and obtain volumetric measurements of coronary lesions through an exploration of the cross sections and longitudinal views of arteries. However, the visualization and subsequent morpho-geometric measurements in IVUS longitudinal cuts are subject to distortion caused by periodic image/vessel motion around the IVUS catheter. Usually, to overcome the image motion artifact ECG-gating and image-gated approaches are proposed, leading to slowing the pullback acquisition or disregarding part of IVUS data. In this paper, we argue that the image motion is due to 3-D vessel geometry as well as cardiac dynamics, and propose a dynamic model based on the tracking of an elliptical vessel approximation to recover the rigid transformation and align IVUS images without loosing any IVUS data. We report an extensive validation with synthetic simulated data and in vivo IVUS sequences of 30 patients achieving an average reduction of the image artifact of 97% in synthetic data and 79% in real-data. Our study shows that IVUS alignment improves longitudinal analysis of the IVUS data and is a necessary step towards accurate reconstruction and volumetric measurements of 3-D IVUS. |
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Copenhaguen (Denmark), |
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1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) |
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IAM; MILAB |
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IAM @ iam @ HRT2006 |
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1552 |
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Author |
Aura Hernandez-Sabate; David Rotger; Debora Gil |
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Image-based ECG sampling of IVUS sequences |
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2008 |
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Proc. IEEE Ultrasonics Symp. IUS 2008 |
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1330-1333 |
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Longitudinal Motion; Image-based ECG-gating; Fourier analysis |
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Longitudinal motion artifacts in IntraVascular UltraSound (IVUS) sequences hinders a properly 3D reconstruction and vessel measurements. Most of current techniques base on the ECG signal to obtain a gated pullback without the longitudinal artifact by using a specific hardware or the ECG signal itself. The potential of IVUS images processing for phase retrieval still remains little explored. In this paper, we present a fast forward image-based algorithm to approach ECG sampling. Inspired on the fact that maximum and minimum lumen areas are related to end-systole and end-diastole, our cardiac phase retrieval is based on the analysis of tissue density of mass along the sequence. The comparison between automatic and manual phase retrieval (0.07 ± 0.07 mm. of error) encourages a deep validation contrasting with ECG signals. |
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Beijing (China) |
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IAM @ iam @ HRG2008 |
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1553 |
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