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Author Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru ; Miguel A. Gonzalez Ballester edit   pdf
doi  isbn
openurl 
  Title Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs Type Book Chapter
  Year 2012 Publication Workshop on Computational and Clinical Applications in Abdominal Imaging Abbreviated Journal  
  Volume 7029 Issue Pages 223–230  
  Keywords medial manifolds, abdomen.  
  Abstract Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D
objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial
manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our
method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs,
exploring the use of medial manifolds for the representation of multi-organ relations.
 
  Address Toronto; Canada;  
  Corporate Author Thesis  
  Publisher Springer Link Place of Publication Berlin Editor H. Yoshida et al  
  Language English Summary Language English Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN (up) 978-3-642-28556-1 Medium  
  Area Expedition Conference ABDI  
  Notes IAM;MV Approved no  
  Call Number IAM @ iam @ VGB2012 Serial 1834  
Permanent link to this record
 

 
Author Carles Sanchez;F. Javier Sanchez; Antoni Rosell; Debora Gil edit   pdf
url  doi
isbn  openurl
  Title An illumination model of the trachea appearance in videobronchoscopy images Type Book Chapter
  Year 2012 Publication Image Analysis and Recognition Abbreviated Journal LNCS  
  Volume 7325 Issue Pages 313-320  
  Keywords Bronchoscopy, tracheal ring, stenosis assesment, trachea appearance model, segmentation  
  Abstract Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways. This imaging modality provides realistic images and allows non-invasive minimal intervention procedures. Tracheal procedures are routinary interventions that require assessment of the percentage of obstructed pathway for injury (stenosis) detection. Visual assessment in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error.
This paper introduces an automatic method for the estimation of steneosed trachea percentage reduction in videobronchoscopic images. We look for tracheal rings , whose deformation determines the degree of obstruction. For ring extraction , we present a ring detector based on an illumination and appearance model. This model allows us to parametrise the ring detection. Finally, we can infer optimal estimation parameters for any video resolution.
 
  Address Aveiro, Portugal  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN (up) 978-3-642-31297-7 Medium  
  Area 800 Expedition Conference ICIAR  
  Notes MV;IAM Approved no  
  Call Number IAM @ iam @ SSR2012 Serial 1898  
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Author Sergio Vera; Miguel A. Gonzalez Ballester; Debora Gil edit   pdf
url  doi
isbn  openurl
  Title Optimal Medial Surface Generation for Anatomical Volume Representations Type Book Chapter
  Year 2012 Publication Abdominal Imaging. Computational and Clinical Applications Abbreviated Journal LNCS  
  Volume 7601 Issue Pages 265-273  
  Keywords Medial surface representation; volume reconstruction  
  Abstract Medial representations are a widely used technique in abdominal organ shape representation and parametrization. Those methods require good medial manifolds as a starting point. Any medial
surface used to parametrize a volume should be simple enough to allow an easy manipulation and complete enough to allow an accurate reconstruction of the volume. Obtaining good quality medial
surfaces is still a problem with current iterative thinning methods. This forces the usage of generic, pre-calculated medial templates that are adapted to the final shape at the cost of a drop in volume reconstruction.
This paper describes an operator for generation of medial structures that generates clean and complete manifolds well suited for their further use in medial representations of abdominal organ volumes. While being simpler than thinning surfaces, experiments show its high performance in volume reconstruction and preservation of medial surface main branching topology.
 
  Address Nice, France  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor Yoshida, Hiroyuki and Hawkes, David and Vannier, MichaelW.  
  Language Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN (up) 978-3-642-33611-9 Medium  
  Area Expedition Conference STACOM  
  Notes IAM Approved no  
  Call Number IAM @ iam @ VGG2012b Serial 1988  
Permanent link to this record
 

 
Author Debora Gil; Jordi Gonzalez; Gemma Sanchez (eds) edit  isbn
openurl 
  Title Computer Vision: Advances in Research and Development Type Book Whole
  Year 2007 Publication Proceedings of the 2nd CVC International Workshop Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher UAB Place of Publication Bellaterra (Spain) Editor Debora Gil; Jordi Gonzalez; Gemma Sanchez  
  Language Summary Language Original Title  
  Series Editor Series Title 2 Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-84-935251-4-9 Medium  
  Area Expedition Conference  
  Notes IAM; ISE; DAG Approved no  
  Call Number IAM @ iam @ GGS2007 Serial 1493  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate edit   pdf
isbn  openurl
  Title Exploring Arterial Dynamics and Structures in IntraVascular Ultrasound Sequences Type Book Whole
  Year 2009 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Cardiovascular diseases are a leading cause of death in developed countries. Most of them are caused by arterial (specially coronary) diseases, mainly caused by plaque accumulation. Such pathology narrows blood flow (stenosis) and affects artery bio- mechanical elastic properties (atherosclerosis). In the last decades, IntraVascular UltraSound (IVUS) has become a usual imaging technique for the diagnosis and follow up of arterial diseases. IVUS is a catheter-based imaging technique which shows a sequence of cross sections of the artery under study. Inspection of a single image gives information about the percentage of stenosis. Meanwhile, inspection of longitudinal views provides information about artery bio-mechanical properties, which can prevent a fatal outcome of the cardiovascular disease. On one hand, dynamics of arteries (due to heart pumping among others) is a major artifact for exploring tissue bio-mechanical properties. On the other one, manual stenosis measurements require a manual tracing of vessel borders, which is a time-consuming task and might suffer from inter-observer variations. This PhD thesis proposes several image processing tools for exploring vessel dy- namics and structures. We present a physics-based model to extract, analyze and correct vessel in-plane rigid dynamics and to retrieve cardiac phase. Furthermore, we introduce a deterministic-statistical method for automatic vessel borders detection. In particular, we address adventitia layer segmentation. An accurate validation pro- tocol to ensure reliable clinical applicability of the methods is a crucial step in any proposal of an algorithm. In this thesis we take special care in designing a valida- tion protocol for each approach proposed and we contribute to the in vivo dynamics validation with a quantitative and objective score to measure the amount of motion suppressed.  
  Address  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-84-937261-6-4 Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ Her2009 Serial 1543  
Permanent link to this record
 

 
Author Carles Sanchez edit  isbn
openurl 
  Title Tracheal Structure Characterization using Geometric and Appearance Models for Efficient Assessment of Stenosis in Videobronchoscopy Type Book Whole
  Year 2014 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Recent advances in endoscopic devices have increased their use for minimal invasive diagnostic and intervention procedures. Among all endoscopic modalities, bronchoscopy is one of the most frequent with around 261 millions of procedures per year. Although the use of bronchoscopy is spread among clinical facilities it presents some drawbacks, being the visual inspection for the assessment of anatomical measurements the most prevalent of them. In
particular, inaccuracies in the estimation of the degree of stenosis (the percentage of obstructed airway) decreases its diagnostic yield and might lead to erroneous treatments. An objective computation of tracheal stenosis in bronchoscopy videos would constitute a breakthrough for this non-invasive technique and a reduction in treatment cost.
This thesis settles the first steps towards on-line reliable extraction of anatomical information from videobronchoscopy for computation of objective measures. In particular, we focus on the computation of the degree of stenosis, which is obtained by comparing the area delimited by a healthy tracheal ring and the stenosed lumen. Reliable extraction of airway structures in interventional videobronchoscopy is a challenging task. This is mainly due to the large variety of acquisition conditions (positions and illumination), devices (different digitalizations) and in videos acquired at the operating room the unpredicted presence of surgical devices (such as probe ends). This thesis contributes to on-line stenosis assessment in several ways. We
propose a parametric strategy for the extraction of lumen and tracheal rings regions based on the characterization of their geometry and appearance that guide a deformable model. The geometric and appearance characterization is based on a physical model describing the way bronchoscopy images are obtained and includes local and global descriptions. In order to ensure a systematic applicability we present a statistical framework to select the optimal
parameters of our method. Experiments perform on the first public annotated database, show that the performance of our method is comparable to the one provided by clinicians and its computation time allows for a on-line implementation in the operating room.
 
  Address  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-84-940902-9-5 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ San2014 Serial 2575  
Permanent link to this record
 

 
Author Patricia Marquez edit  isbn
openurl 
  Title A Confidence Framework for the Assessment of Optical Flow Performance Type Book Whole
  Year 2015 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Optical Flow (OF) is the input of a wide range of decision support systems such as car driver assistance, UAV guiding or medical diagnose. In these real situations, the absence of ground truth forces to assess OF quality using quantities computed from either sequences or the computed optical flow itself. These quantities are generally known as Confidence Measures, CM. Even if we have a proper confidence measure we still need a way to evaluate its ability to discard pixels with an OF prone to have a large error. Current approaches only provide a descriptive evaluation of the CM performance but such approaches are not capable to fairly compare different confidence measures and optical flow algorithms. Thus, it is of prime importance to define a framework and a general road map for the evaluation of optical flow performance.

This thesis provides a framework able to decide which pairs “ optical flow – confidence measure” (OF-CM) are best suited for optical flow error bounding given a confidence level determined by a decision support system. To design this framework we cover the following points:

Descriptive scores. As a first step, we summarize and analyze the sources of inaccuracies in the output of optical flow algorithms. Second, we present several descriptive plots that visually assess CM capabilities for OF error bounding. In addition to the descriptive plots, given a plot representing OF-CM capabilities to bound the error, we provide a numeric score that categorizes the plot according to its decreasing profile, that is, a score assessing CM performance.
Statistical framework. We provide a comparison framework that assesses the best suited OF-CM pair for error bounding that uses a two stage cascade process. First of all we assess the predictive value of the confidence measures by means of a descriptive plot. Then, for a sample of descriptive plots computed over training frames, we obtain a generic curve that will be used for sequences with no ground truth. As a second step, we evaluate the obtained general curve and its capabilities to really reflect the predictive value of a confidence measure using the variability across train frames by means of ANOVA.

The presented framework has shown its potential in the application on clinical decision support systems. In particular, we have analyzed the impact of the different image artifacts such as noise and decay to the output of optical flow in a cardiac diagnose system and we have improved the navigation inside the bronchial tree on bronchoscopy.
 
  Address July 2015  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor Debora Gil; Aura Hernandez  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-84-943427-2-1 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ Mar2015 Serial 2687  
Permanent link to this record
 

 
Author Sergio Vera edit  isbn
openurl 
  Title Anatomic Registration based on Medial Axis Parametrizations Type Book Whole
  Year 2015 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Image registration has been for many years the gold standard method to bring two images into correspondence. It has been used extensively in the eld of medical imaging in order to put images of di erent patients into a common overlapping spatial position. However, medical image registration is a slow, iterative optimization process, where many variables and prone to fall into the pit traps local minima.
A coordinate system parameterizing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to speci c anatomical sites, parameterizations ensure integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric meshes over the surface of anatomical shapes, given their ability to set values at speci c locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at discrete sites of limited geometric diversity.
The medial surface of the shape can be used to provide a continuous basis for the de nition of a depth coordinate. However, given that di erent methods for generation of medial surfaces generate di erent manifolds, not all of them are equally suited to be the basis of radial coordinate for a parameterization. It would be desirable that the medial surface will be smooth, and robust to surface shape noise, with low number of spurious branches or surfaces.
In this thesis we present methods for computation of smooth medial manifolds and apply them to the generation of for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the volume medial surface. This reference system sets a solid base for creating anatomical models of the anatomical shapes, and allows comparing several patients in a common framework of reference.
 
  Address November 2015  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor Debora Gil; Miguel Angel Gonzalez Ballester  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-84-943427-8-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ Ver2015 Serial 2708  
Permanent link to this record
 

 
Author David Roche; Debora Gil; Jesus Giraldo edit  doi
isbn  openurl
  Title Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? Type Book Chapter
  Year 2014 Publication G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology Abbreviated Journal  
  Volume 796 Issue 3 Pages 159-181  
  Keywords β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model  
  Abstract Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Netherlands Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0065-2598 ISBN (up) 978-94-007-7422-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number IAM @ iam @ RGG2014 Serial 2197  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil edit   pdf
url  doi
isbn  openurl
  Title The Benefits of IVUS Dynamics for Retrieving Stable Models of Arteries Type Book Chapter
  Year 2012 Publication Intravascular Ultrasound Abbreviated Journal  
  Volume Issue Pages 185-206  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Intech Place of Publication Editor Yasuhiro Honda  
  Language English Summary Language english Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-953-307-900-4 Medium  
  Area Expedition Conference  
  Notes IAM; ADAS Approved no  
  Call Number IAM @ iam @ HeG2012 Serial 1684  
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