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Author Jaume Garcia; Debora Gil; Francesc Carreras; Sandra Pujades; R.Leta edit   pdf
openurl 
  Title Modelització 4-Dimensional de la Funció Siatólica del Ventricle Esquerre Type Conference Article
  Year 2007 Publication XIX Congrés de la Societat Catalana de Cardiologia de Barcelona Abbreviated Journal  
  Volume Issue Pages (down) 133-134  
  Keywords  
  Abstract L’evolució tecnològica en el tractament de les imatges mèdiques permet reconstruir, amb el software apropiat, imatges tridimensionals de les estructures cardiovasculars i dotar-les de moviment. Les imatges 4D resultants faciliten l’estudi de la fisiopatologia de la insuficiència cardíaca en base als transtorns de l’activació electromecànica ventricular, el que pot ser d’interès en el procés de selecció de pacients candidats a teràpies de resincronització. Presentem els resultats preliminars de la reconstrucció 4D del ventricle esquerre (VE) a partir de les seqüències de tagging miocàrdic del VE.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona (Spain) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGC2007 Serial 1505  
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Author Debora Gil; Petia Radeva; Josefina Mauri edit   pdf
openurl 
  Title Ivus Segmentation Via a Regularized Curvature Flow Type Conference Article
  Year 2002 Publication X Congreso Anual de la Sociedad Española de Ingeniería Biomédica CASEIB 2002 Abbreviated Journal  
  Volume Issue Pages (down) 133-136  
  Keywords  
  Abstract Cardiac diseases are diagnosed and treated through a study of the morphology and dynamics of cardiac arteries. In- travascular Ultrasound (IVUS) imaging is of high interest to physicians since it provides both information. At the current state-of-the-art in image segmentation, a robust detection of the arterial lumen in IVUS demands manual intervention or ECG-gating. Manual intervention is a tedious and time consuming task that requires experienced observers, meanwhile ECG-gating is an acquisition technique not available in all clinical centers. We introduce a parametric algorithm that detects the arterial luminal border in in vivo sequences. The method consist in smoothing the sequences’ level surfaces under a regularized mean curvature flow that admits non-trivial steady states. The flow is based on a measure of the surface local smoothness that takes into account regularity of the surface curvature.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Saragossa, Espanya Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GRM2002 Serial 1536  
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Author Oriol Rodriguez-Leon; Debora Gil; Eduard Fernandez-Nofrerias; H.Tizon; S.Montserrat; Vicente del Valle;Josefina Mauri edit  openurl
  Title Caracterització de la Perfusió Miocàrdica mitjançant anàlisi estadístic de l espectre en l angiografia de contrast Type Conference Article
  Year 2007 Publication XIX Congrés de la Societat Catalana de Cardiologia de Barcelona Abbreviated Journal  
  Volume Issue Pages (down) 130  
  Keywords  
  Abstract La valoració de la integritat de la microcirculació coronària aporta informació pronòstica en pacients amb infart agut de miocardi en els que es realitza angioplastia primària. Aquesta valoració és subjectiva i presenta una important variabilitat si no es duta a terme per personal experimentat. Presentem una eina d’anàlisi d’imatge que permet fer una valoració de la microcirculació coronària a partir de seqüències d’angiografia. Hem analitzat les variacions locals en el nivell de gris de la imatge durant la seqüència angiogràfica. Hem identificat els principals fenòmens observats (respiració, batec cardíac, tinció arterial, tinció miocàrdica i soroll radiològic) mitjançant un anàlisi estadístic de l’espectre de Fourier de l’evolució al llarg del temps de la mitja local. Aquest mateix anàlisis permet determinat la influència de cadascun d’ells en la extracció del patró de tinció i selecciona la respiració com el fenomen que més distorsiona el patró de tinció original. Els descriptors proposats s’obtenen fora del rang espectral respiratori. Hem testat la seva capacitat per a detectar els tres fenòmens principals (tinció miocàrdica (MS), tinció arterial (AS) i soroll (NS)) independentment de la respiració. La capacitat de discriminació dels descriptors ha estat valorada mitjançant un mètode de crossvalidation en 30 seqüències d’angiografia. Els descriptors emprats permeten caracteritzar la tinció miocàrdica amb una alta eficiència i fiabilitat. A més no hi ha diferències significatives en l’anàlisi de les seqüències obtingudes amb el pacient respirant amb normalitat o en apnea  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona (Spain) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ RGF2007 Serial 1639  
Permanent link to this record
 
 
Author Oriol Rodriguez-Leon; Debora Gil; Eduard Fernandez-Nofrerias edit  openurl
  Title Analisis en los cambios en el nivel de gris en las secuencias angiograficas mediante descriptores estadisticos para determinar la perfusion miocardica Type Journal Article
  Year 2006 Publication Revista Española de Cardiología Abbreviated Journal REC  
  Volume 59 Supl 2-166 Issue 2 Pages (down) 128  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ RGF2006 Serial 1640  
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Author Jaume Garcia; Debora Gil; Aura Hernandez-Sabate edit   pdf
doi  openurl
  Title Endowing Canonical Geometries to Cardiac Structures Type Book Chapter
  Year 2010 Publication Statistical Atlases And Computational Models Of The Heart Abbreviated Journal  
  Volume 6364 Issue Pages (down) 124-133  
  Keywords  
  Abstract International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view.		  
  Address  
  Corporate Author Thesis  
  Publisher Springer Berlin / Heidelberg Place of Publication Editor Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A.  
  Language Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGH2010b Serial 1515  
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Author Patricia Marquez;Debora Gil;Aura Hernandez-Sabate edit   pdf
doi  isbn
openurl 
  Title A Complete Confidence Framework for Optical Flow Type Conference Article
  Year 2012 Publication 12th European Conference on Computer Vision – Workshops and Demonstrations Abbreviated Journal  
  Volume 7584 Issue 2 Pages (down) 124-133  
  Keywords Optical flow, confidence measures, sparsification plots, error prediction plots  
  Abstract Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.  
  Address  
  Corporate Author Thesis  
  Publisher Springer-Verlag Place of Publication Florence, Italy, October 7-13, 2012 Editor Andrea Fusiello, Vittorio Murino ,Rita Cucchiara  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-3-642-33867-0 Medium  
  Area Expedition Conference ECCVW  
  Notes IAM;ADAS; Approved no  
  Call Number IAM @ iam @ MGH2012b Serial 1991  
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Author Jaume Garcia; Debora Gil; Francesc Carreras ; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados edit   pdf
openurl 
  Title Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat Type Conference Article
  Year 2008 Publication XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres Abbreviated Journal  
  Volume Issue Pages (down) 122  
  Keywords  
  Abstract Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica		  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona Editor  
  Language catalan Summary Language catalan Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGC2008c Serial 1504  
Permanent link to this record
 
 
Author Joel Barajas; Jaume Garcia; Karla Lizbeth Caballero; Francesc Carreras; Sandra Pujades; Petia Radeva edit   pdf
isbn  openurl
  Title Correction of Misalignment Artifacts Among 2-D Cardiac MR Images in 3-D Space Type Conference Article
  Year 2006 Publication 1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) Abbreviated Journal  
  Volume 3217 Issue Pages (down) 114-121  
  Keywords  
  Abstract Cardiac Magnetic Resonance images offer the opportunity to study the heart in detail. One of the main issues in its modelling is to create an accurate 3-D reconstruction of the left ventricle from 2-D views. A first step to achieve this goal is the correct registration among the different image planes due to patient movements. In this article, we present an accurate method to correct displacement artifacts using the Normalized Mutual Information. Here, the image views are treated as planes in order to diminish the approximation error caused by the association of a certain thickness, and moved simultaneously to avoid any kind of bias in the alignment process. This method has been validated using real and syntectic plane displacements, yielding promising results.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Copenhagen (Denmark) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-3-540-22977-3 Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ BGC2006 Serial 1485  
Permanent link to this record
 
 
Author Debora Gil; Petia Radeva edit   pdf
doi  openurl
  Title Extending anisotropic operators to recover smooth shapes Type Journal Article
  Year 2005 Publication Computer Vision and Image Understanding Abbreviated Journal  
  Volume 99 Issue 1 Pages (down) 110-125  
  Keywords Contour completion; Functional extension; Differential operators; Riemmanian manifolds; Snake segmentation  
  Abstract Anisotropic differential operators are widely used in image enhancement processes. Recently, their property of smoothly extending functions to the whole image domain has begun to be exploited. Strong ellipticity of differential operators is a requirement that ensures existence of a unique solution. This condition is too restrictive for operators designed to extend image level sets: their own functionality implies that they should restrict to some vector field. The diffusion tensor that defines the diffusion operator links anisotropic processes with Riemmanian manifolds. In this context, degeneracy implies restricting diffusion to the varieties generated by the vector fields of positive eigenvalues, provided that an integrability condition is satisfied. We will use that any smooth vector field fulfills this integrability requirement to design line connection algorithms for contour completion. As application we present a segmenting strategy that assures convergent snakes whatever the geometry of the object to be modelled is.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1077-3142 ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GIR2005 Serial 1530  
Permanent link to this record
 
 
Author Marta Ligero; Alonso Garcia Ruiz; Cristina Viaplana; Guillermo Villacampa; Maria V Raciti; Jaid Landa; Ignacio Matos; Juan Martin Liberal; Maria Ochoa de Olza; Cinta Hierro; Joaquin Mateo; Macarena Gonzalez; Rafael Morales Barrera; Cristina Suarez; Jordi Rodon; Elena Elez; Irene Braña; Eva Muñoz-Couselo; Ana Oaknin; Roberta Fasani; Paolo Nuciforo; Debora Gil; Carlota Rubio Perez; Joan Seoane; Enriqueta Felip; Manuel Escobar; Josep Tabernero; Joan Carles; Rodrigo Dienstmann; Elena Garralda; Raquel Perez Lopez edit  url
doi  openurl
  Title A CT-based radiomics signature is associated with response to immune checkpoint inhibitors in advanced solid tumors Type Journal Article
  Year 2021 Publication Radiology Abbreviated Journal  
  Volume 299 Issue 1 Pages (down) 109-119  
  Keywords  
  Abstract Background Reliable predictive imaging markers of response to immune checkpoint inhibitors are needed. Purpose To develop and validate a pretreatment CT-based radiomics signature to predict response to immune checkpoint inhibitors in advanced solid tumors. Materials and Methods In this retrospective study, a radiomics signature was developed in patients with advanced solid tumors (including breast, cervix, gastrointestinal) treated with anti-programmed cell death-1 or programmed cell death ligand-1 monotherapy from August 2012 to May 2018 (cohort 1). This was tested in patients with bladder and lung cancer (cohorts 2 and 3). Radiomics variables were extracted from all metastases delineated at pretreatment CT and selected by using an elastic-net model. A regression model combined radiomics and clinical variables with response as the end point. Biologic validation of the radiomics score with RNA profiling of cytotoxic cells (cohort 4) was assessed with Mann-Whitney analysis. Results The radiomics signature was developed in 85 patients (cohort 1: mean age, 58 years ± 13 [standard deviation]; 43 men) and tested on 46 patients (cohort 2: mean age, 70 years ± 12; 37 men) and 47 patients (cohort 3: mean age, 64 years ± 11; 40 men). Biologic validation was performed in a further cohort of 20 patients (cohort 4: mean age, 60 years ± 13; 14 men). The radiomics signature was associated with clinical response to immune checkpoint inhibitors (area under the curve [AUC], 0.70; 95% CI: 0.64, 0.77; P < .001). In cohorts 2 and 3, the AUC was 0.67 (95% CI: 0.58, 0.76) and 0.67 (95% CI: 0.56, 0.77; P < .001), respectively. A radiomics-clinical signature (including baseline albumin level and lymphocyte count) improved on radiomics-only performance (AUC, 0.74 [95% CI: 0.63, 0.84; P < .001]; Akaike information criterion, 107.00 and 109.90, respectively). Conclusion A pretreatment CT-based radiomics signature is associated with response to immune checkpoint inhibitors, likely reflecting the tumor immunophenotype. © RSNA, 2021 Online supplemental material is available for this article. See also the editorial by Summers in this issue.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.145 Approved no  
  Call Number Admin @ si @ LGV2021 Serial 3593  
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