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Author |
Aura Hernandez-Sabate; Debora Gil; David Roche; Monica M. S. Matsumoto; Sergio S. Furuie |
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Title |
Inferring the Performance of Medical Imaging Algorithms |
Type |
Conference Article |
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Year |
2011 |
Publication |
14th International Conference on Computer Analysis of Images and Patterns |
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Volume |
6854 |
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Pages |
520-528 |
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Keywords |
Validation, Statistical Inference, Medical Imaging Algorithms. |
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Abstract |
Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence. |
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Sevilla |
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Publisher |
Springer-Verlag Berlin Heidelberg |
Place of Publication |
Berlin |
Editor |
Pedro Real; Daniel Diaz-Pernil; Helena Molina-Abril; Ainhoa Berciano; Walter Kropatsch |
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CAIP |
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IAM; ADAS |
Approved |
no |
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Call Number |
IAM @ iam @ HGR2011 |
Serial |
1676 |
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Permanent link to this record |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
An inference model for analyzing termination conditions of Evolutionary Algorithms |
Type |
Conference Article |
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Year |
2011 |
Publication |
14th Congrès Català en Intel·ligencia Artificial |
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Volume |
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Pages |
216-225 |
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Keywords |
Evolutionary Computation Convergence, Termination Conditions, Statistical Inference |
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Abstract |
In real-world problems, it is mandatory to design a termination condition for Evolutionary Algorithms (EAs) ensuring stabilization close to the unknown optimum. Distribution-based quantities are good candidates as far as suitable parameters are used. A main limitation for application to real-world problems is that such parameters strongly depend on the topology of the objective function, as well as, the EA paradigm used.
We claim that the termination problem would be fully solved if we had a model measuring to what extent a distribution-based quantity asymptotically behaves like the solution accuracy. We present a regression-prediction model that relates any two given quantities and reports if they can be statistically swapped as termination conditions. Our framework is applied to two issues. First, exploring if the parameters involved in the computation of distribution-based quantities influence their asymptotic behavior. Second, to what extent existing distribution-based quantities can be asymptotically exchanged for the accuracy of the EA solution. |
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Lleida, Catalonia (Spain) |
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Corporate Author |
Associació Catalana Intel·ligència Artificial |
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978-1-60750-841-0 |
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CCIA |
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IAM |
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no |
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Call Number |
IAM @ iam @ RGG2011a |
Serial |
1677 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Using statistical inference for designing termination conditions ensuring convergence of Evolutionary Algorithms |
Type |
Conference Article |
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Year |
2011 |
Publication |
11th European Conference on Artificial Life |
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A main challenge in Evolutionary Algorithms (EAs) is determining a termination condition ensuring stabilization close to the optimum in real-world applications. Although for known test functions distribution-based quantities are good candidates (as far as suitable parameters are used), in real-world problems an open question still remains unsolved. How can we estimate an upper-bound for the termination condition value ensuring a given accuracy for the (unknown) EA solution?
We claim that the termination problem would be fully solved if we defined a quantity (depending only on the EA output) behaving like the solution accuracy. The open question would be, then, satisfactorily answered if we had a model relating both quantities, since accuracy could be predicted from the alternative quantity. We present a statistical inference framework addressing two topics: checking the correlation between the two quantities and defining a regression model for predicting (at a given confidence level) accuracy values from the EA output. |
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Paris, France |
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ECAL |
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IAM; |
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no |
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Call Number |
IAM @ iam @ RGG2011b |
Serial |
1678 |
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Author |
Ferran Poveda; Debora Gil ;Albert Andaluz ;Enric Marti |
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Title |
Multiscale Tractography for Representing Heart Muscular Architecture |
Type |
Conference Article |
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Year |
2011 |
Publication |
In MICCAI 2011 Workshop on Computational Diffusion MRI |
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Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. Although the muscular architecture of the heart has been debated by countless researchers, the controversy is still alive. Diffusion Tensor MRI, DT-MRI, is a unique imaging technique for computational validation of the muscular structure of the heart. By the complex arrangement of myocites, existing techniques can not provide comprehensive descriptions of the global muscular architecture. In this paper we introduce a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and indicate a global helical organization |
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English |
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english |
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CDRMI |
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IAM |
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no |
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Call Number |
IAM @ iam @ PGA2011 |
Serial |
1681 |
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Author |
Patricia Marquez; Debora Gil; Aura Hernandez-Sabate |
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Title |
A Confidence Measure for Assessing Optical Flow Accuracy in the Absence of Ground Truth |
Type |
Conference Article |
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Year |
2011 |
Publication |
IEEE International Conference on Computer Vision – Workshops |
Abbreviated Journal |
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Issue |
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Pages |
2042-2049 |
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Keywords |
IEEE International Conference on Computer Vision – Workshops |
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Abstract |
Optical flow is a valuable tool for motion analysis in autonomous navigation systems. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in real world sequences. This paper introduces a measure of optical flow accuracy for Lucas-Kanade based flows in terms of the numerical stability of the data-term. We call this measure optical flow condition number. A statistical analysis over ground-truth data show a good statistical correlation between the condition number and optical flow error. Experiments on driving sequences illustrate its potential for autonomous navigation systems. |
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Publisher |
IEEE |
Place of Publication |
Barcelona (Spain) |
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Language |
English |
Summary Language |
English |
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ICCVW |
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Notes |
IAM; ADAS |
Approved |
no |
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Call Number |
IAM @ iam @ MGH2011 |
Serial |
1682 |
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Permanent link to this record |
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Author |
Aura Hernandez-Sabate; Debora Gil |
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Title |
The Benefits of IVUS Dynamics for Retrieving Stable Models of Arteries |
Type |
Book Chapter |
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Year |
2012 |
Publication |
Intravascular Ultrasound |
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Pages |
185-206 |
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Publisher |
Intech |
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Editor |
Yasuhiro Honda |
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Language |
English |
Summary Language |
english |
Original Title |
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Series Editor |
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ISBN |
978-953-307-900-4 |
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Notes |
IAM; ADAS |
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no |
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Call Number |
IAM @ iam @ HeG2012 |
Serial |
1684 |
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Permanent link to this record |
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Author |
Debora Gil; Agnes Borras; Manuel Ballester; Francesc Carreras; Ruth Aris; Manuel Vazquez; Enric Marti; Ferran Poveda |
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Title |
MIOCARDIA: Integrating cardiac function and muscular architecture for a better diagnosis |
Type |
Conference Article |
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Year |
2011 |
Publication |
14th International Symposium on Applied Sciences in Biomedical and Communication Technologies |
Abbreviated Journal |
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Abstract |
Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. The MIOCARDIA project is a multidisciplinary project in cooperation with l'Hospital de la Santa Creu i de Sant Pau, Clinica la Creu Blanca and Barcelona Supercomputing Center. The ultimate goal of this project is defining a computational model of the myocardium. The model takes into account the deep interrelation between the anatomy and the mechanics of the heart. The paper explains the workflow of the MIOCARDIA project. It also introduces a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and provides evidences of a global helical organization. |
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Address |
Barcelona; Spain |
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Corporate Author |
Association for Computing Machinery |
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Publisher |
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Place of Publication |
Barcelona, Spain |
Editor |
Association for Computing Machinery |
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Language |
english |
Summary Language |
english |
Original Title |
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Series Editor |
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ISBN |
978-1-4503-0913-4 |
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Conference |
ISABEL |
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Notes |
IAM |
Approved |
no |
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Call Number |
IAM @ iam @ GGB2011 |
Serial |
1691 |
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Permanent link to this record |
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Author |
Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru; Miguel Angel Gonzalez Ballester |
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Title |
Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs |
Type |
Book Chapter |
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Year |
2012 |
Publication |
Workshop on Computational and Clinical Applications in Abdominal Imaging |
Abbreviated Journal |
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Volume |
7029 |
Issue |
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Pages |
223–230 |
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Keywords |
medial manifolds, abdomen. |
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Abstract |
Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D
objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial
manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our
method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs,
exploring the use of medial manifolds for the representation of multi-organ relations. |
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Address |
Toronto; Canada; |
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Publisher |
Springer Link |
Place of Publication |
Berlin |
Editor |
H. Yoshida et al |
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Language |
English |
Summary Language |
English |
Original Title |
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Series Title |
Lecture Notes in Computer Science |
Abbreviated Series Title |
LNCS |
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ISSN |
0302-9743 |
ISBN |
978-3-642-28556-1 |
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ABDI |
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Notes |
IAM;MV |
Approved |
no |
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Call Number |
IAM @ iam @ VGB2012 |
Serial |
1834 |
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Permanent link to this record |
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Author |
Sergio Vera; Debora Gil; Antonio Lopez; Miguel Angel Gonzalez Ballester |
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Title |
Multilocal Creaseness Measure |
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Journal |
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Year |
2012 |
Publication |
The Insight Journal |
Abbreviated Journal |
IJ |
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Volume |
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Issue |
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Pages |
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Keywords |
Ridges, Valley, Creaseness, Structure Tensor, Skeleton, |
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Abstract |
This document describes the implementation using the Insight Toolkit of an algorithm for detecting creases (ridges and valleys) in N-dimensional images, based on the Local Structure Tensor of the image. In addition to the filter used to calculate the creaseness image, a filter for the computation of the structure tensor is also included in this submission. |
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Corporate Author |
Alma IT Systems |
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Language |
english |
Summary Language |
english |
Original Title |
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Series Editor |
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Notes |
IAM;ADAS; |
Approved |
no |
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Call Number |
IAM @ iam @ VGL2012 |
Serial |
1840 |
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Permanent link to this record |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Assessing agonist efficacy in an uncertain Em world |
Type |
Conference Article |
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Year |
2012 |
Publication |
40th Keystone Symposia on mollecular and celular biology |
Abbreviated Journal |
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Volume |
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Issue |
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Pages |
79 |
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Abstract |
The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed. |
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Address |
Fairmont Banff Springs, Banff, Alberta, Canada |
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Corporate Author |
Keystone Symposia |
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Publisher |
Keystone Symposia |
Place of Publication |
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Editor |
A. Christopoulus and M. Bouvier |
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Language |
english |
Summary Language |
english |
Original Title |
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Series Editor |
Keystone Symposia |
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Conference |
KSMCB |
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Notes |
IAM |
Approved |
no |
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Call Number |
IAM @ iam @ RGG2012 |
Serial |
1855 |
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Permanent link to this record |
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Author |
Alberto Hidalgo; Ferran Poveda; Enric Marti;Debora Gil;Albert Andaluz; Francesc Carreras; Manuel Ballester |
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Title |
Evidence of continuous helical structure of the cardiac ventricular anatomy assessed by diffusion tensor imaging magnetic resonance multiresolution tractography |
Type |
Journal Article |
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Year |
2012 |
Publication |
European Radiology |
Abbreviated Journal |
ECR |
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Volume |
3 |
Issue |
1 |
Pages |
361-362 |
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Keywords |
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Abstract |
Deep understanding of myocardial structure linking morphology and func- tion of the heart would unravel crucial knowledge for medical and surgical clinical procedures and studies. Diffusion tensor MRI provides a discrete measurement of the 3D arrangement of myocardial fibres by the observation of local anisotropic
diffusion of water molecules in biological tissues. In this work, we present a multi- scale visualisation technique based on DT-MRI streamlining capable of uncovering additional properties of the architectural organisation of the heart. Methods and Materials: We selected the John Hopkins University (JHU) Canine Heart Dataset, where the long axis cardiac plane is aligned with the scanner’s Z- axis. Their equipment included a 4-element passed array coil emitting a 1.5 T. For DTI acquisition, a 3D-FSE sequence is apply. We used 200 seeds for full-scale tractography, while we applied a MIP mapping technique for simplified tractographic reconstruction. In this case, we reduced each DTI 3D volume dimensions by order- two magnitude before streamlining.
Our simplified tractographic reconstruction method keeps the main geometric features of fibres, allowing for an easier identification of their global morphological disposition, including the ventricular basal ring. Moreover, we noticed a clearly visible helical disposition of the myocardial fibres, in line with the helical myocardial band ventricular structure described by Torrent-Guasp. Finally, our simplified visualisation with single tracts identifies the main segments of the helical ventricular architecture.
DT-MRI makes possible the identification of a continuous helical architecture of the myocardial fibres, which validates Torrent-Guasp’s helical myocardial band ventricular anatomical model. |
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Address |
Viena, Austria |
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Publisher |
Springer Link |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1869-4101 |
ISBN |
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Medium |
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Area |
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Conference |
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Notes |
IAM |
Approved |
no |
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Call Number |
IAM @ iam @ HPM2012 |
Serial |
1858 |
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Permanent link to this record |
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Author |
Carles Sanchez;F. Javier Sanchez; Antoni Rosell; Debora Gil |
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Title |
An illumination model of the trachea appearance in videobronchoscopy images |
Type |
Book Chapter |
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Year |
2012 |
Publication |
Image Analysis and Recognition |
Abbreviated Journal |
LNCS |
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Volume |
7325 |
Issue |
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Pages |
313-320 |
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Keywords |
Bronchoscopy, tracheal ring, stenosis assesment, trachea appearance model, segmentation |
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Abstract |
Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways. This imaging modality provides realistic images and allows non-invasive minimal intervention procedures. Tracheal procedures are routinary interventions that require assessment of the percentage of obstructed pathway for injury (stenosis) detection. Visual assessment in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error.
This paper introduces an automatic method for the estimation of steneosed trachea percentage reduction in videobronchoscopic images. We look for tracheal rings , whose deformation determines the degree of obstruction. For ring extraction , we present a ring detector based on an illumination and appearance model. This model allows us to parametrise the ring detection. Finally, we can infer optimal estimation parameters for any video resolution. |
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Address |
Aveiro, Portugal |
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Corporate Author |
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Thesis |
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Publisher |
Springer Berlin Heidelberg |
Place of Publication |
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Series Editor |
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Series Title |
Lecture Notes in Computer Science |
Abbreviated Series Title |
LNCS |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0302-9743 |
ISBN |
978-3-642-31297-7 |
Medium |
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Area |
800 |
Expedition |
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Conference |
ICIAR |
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Notes |
MV;IAM |
Approved |
no |
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Call Number |
IAM @ iam @ SSR2012 |
Serial |
1898 |
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Permanent link to this record |
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Author |
Patricia Marquez; Debora Gil ; Aura Hernandez-Sabate |
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Title |
Error Analysis for Lucas-Kanade Based Schemes |
Type |
Conference Article |
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Year |
2012 |
Publication |
9th International Conference on Image Analysis and Recognition |
Abbreviated Journal |
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Volume |
7324 |
Issue |
I |
Pages |
184-191 |
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Keywords |
Optical flow, Confidence measure, Lucas-Kanade, Cardiac Magnetic Resonance |
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Abstract |
Optical flow is a valuable tool for motion analysis in medical imaging sequences. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in medical sequences. This paper presents an error analysis of Lucas-Kanade schemes in terms of intrinsic design errors and numerical stability of the algorithm. Our analysis provides a confidence measure that is naturally correlated to the accuracy of the flow field. Our experiments show the higher predictive value of our confidence measure compared to existing measures. |
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Address |
Aveiro, Portugal |
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Corporate Author |
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Thesis |
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Publisher |
Springer-Verlag Berlin Heidelberg |
Place of Publication |
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Editor |
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Language |
english |
Summary Language |
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Original Title |
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Series Editor |
Campilho, Aurélio and Kamel, Mohamed |
Series Title |
Lecture Notes in Computer Science |
Abbreviated Series Title |
LNCS |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0302-9743 |
ISBN |
978-3-642-31294-6 |
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Conference |
ICIAR |
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Notes |
IAM |
Approved |
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Call Number |
IAM @ iam @ MGH2012a |
Serial |
1899 |
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Permanent link to this record |
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Author |
Albert Andaluz; Francesc Carreras; Cristina Santa Marta;Debora Gil |
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Title |
Myocardial torsion estimation with Tagged-MRI in the OsiriX platform |
Type |
Conference Article |
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Year |
2012 |
Publication |
ISBI Workshop on Open Source Medical Image Analysis software |
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Abstract |
Myocardial torsion (MT) plays a crucial role in the assessment of the functionality of the
left ventricle. For this purpose, the IAM group at the CVC has developed the Harmonic Phase Flow (HPF) plugin for the Osirix DICOM platform . We have validated its funcionalty on sequences acquired using different protocols and including healthy and pathological cases. Results show similar torsion trends for SPAMM acquisitions, with pathological cases introducing expected deviations from the ground truth. Finally, we provide the plugin free of charge at http://iam.cvc.uab.es |
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Address |
Barcelona, Spain |
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Publisher |
IEEE |
Place of Publication |
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Editor |
Wiro Niessen (Erasmus MC) and Marc Modat (UCL) |
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ISBI |
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Notes |
IAM |
Approved |
no |
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Call Number |
IAM @ iam @ ACS2012 |
Serial |
1900 |
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Permanent link to this record |
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Author |
Patricia Marquez; Debora Gil; Aura Hernandez-Sabate |
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Title |
Evaluation of the Capabilities of Confidence Measures for Assessing Optical Flow Quality |
Type |
Conference Article |
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Year |
2013 |
Publication |
ICCV Workshop on Computer Vision in Vehicle Technology: From Earth to Mars |
Abbreviated Journal |
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Volume |
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Issue |
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Pages |
624-631 |
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Abstract |
Assessing Optical Flow (OF) quality is essential for its further use in reliable decision support systems. The absence of ground truth in such situations leads to the computation of OF Confidence Measures (CM) obtained from either input or output data. A fair comparison across the capabilities of the different CM for bounding OF error is required in order to choose the best OF-CM pair for discarding points where OF computation is not reliable. This paper presents a statistical probabilistic framework for assessing the quality of a given CM. Our quality measure is given in terms of the percentage of pixels whose OF error bound can not be determined by CM values. We also provide statistical tools for the computation of CM values that ensures a given accuracy of the flow field. |
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Address |
Sydney; Australia; December 2013 |
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Conference |
CVTT:E2M |
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Notes |
IAM; ADAS; 600.044; 600.057; 601.145 |
Approved |
no |
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Call Number |
Admin @ si @ MGH2013b |
Serial |
2351 |
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Permanent link to this record |