Abstract: We present a fully automatic methodology for the detection of the Media-Adventitia border (MAb) in human coronary artery in Intravascular Ultrasound (IVUS) images. A robust border detection is achieved by means of a holistic interpretation of the detection problem where the target object, i.e. the media layer, is considered as part of the whole vessel in the image and all the relationships between tissues are learnt. A fairly general framework exploiting multi-class tissue characterization as well as contextual information on the morphology and the appearance of the tissues is presented. The methodology is (i) validated through an exhaustive comparison with both Inter-observer variability on two challenging databases and (ii) compared with state-of-the-art methods for the detection of the MAb in IVUS. The obtained averaged values for the mean radial distance and the percentage of area difference are 0.211 mm and 10.1%, respectively. The applicability of the proposed methodology to clinical practice is also discussed.

Abstract: In this thesis we tackle the problem of automatic characterization of human coronary vessel in Intravascular Ultrasound (IVUS) image modality. The basis for the whole characterization process is machine learning applied to multi-class problems. In all the presented approaches, the Error-Correcting Output Codes (ECOC) framework is used as central element for the design of multi-class classifiers.
Two main topics are tackled in this thesis. First, the automatic detection of the vessel borders is presented. For this purpose, a novel context-aware classifier for multi-class classification of the vessel morphology is presented, namely ECOC-DRF. Based on ECOC-DRF, the lumen border and the media-adventitia border in IVUS are robustly detected by means of a novel holistic approach, achieving an error comparable with inter-observer variability and with state of the art methods.
The two vessel borders define the atheroma area of the vessel. In this area, tissue characterization is required. For this purpose, we present a framework for automatic plaque characterization by processing both texture in IVUS images and spectral information in raw Radio Frequency data. Furthermore, a novel method for fusing in-vivo and in-vitro IVUS data for plaque characterization is presented, namely pSFFS. The method demonstrates to effectively fuse data generating a classifier that improves the tissue characterization in both in-vitro and in-vivo datasets.
A novel method for automatic video summarization in IVUS sequences is also presented. The method aims to detect the key frames of the sequence, i.e., the frames representative of morphological changes. This novel method represents the basis for video summarization in IVUS as well as the markers for the partition of the vessel into morphological and clinically interesting events.
Finally, multi-class learning based on ECOC is applied to lung tissue characterization in Computed Tomography. The novel proposed approach, based on supervised and unsupervised learning, achieves accurate tissue classification on a large and heterogeneous dataset.

Abstract: Depth perception is a key aspect of human vision. It is a routine and essential visual task that the human do effortlessly in many daily activities. This has often been associated with stereo vision, but humans have an amazing ability to perceive depth relations even from a single image by using several monocular cues.
In the computer vision field, if image depth information were available, many tasks could be posed from a different perspective for the sake of higher performance and robustness. Nevertheless, given a single image, this possibility is usually discarded, since obtaining depth information has frequently been performed by three-dimensional reconstruction techniques, requiring two or more images of the same scene taken from different viewpoints. Recently, some proposals have shown the feasibility of computing depth information from single images. In essence, the idea is to take advantage of a priori knowledge of the acquisition conditions and the observed scene to estimate depth from monocular pictorial cues. These approaches try to precisely estimate the scene depth maps by employing computationally demanding techniques. However, to assist many computer vision algorithms, it is not really necessary computing a costly and detailed depth map of the image. Indeed, just a rough depth description can be very valuable in many problems.
In this thesis, we have demonstrated how coarse depth information can be integrated in different tasks following alternative strategies to obtain more precise and robust results. In that sense, we have proposed a simple, but reliable enough technique, whereby image scene regions are categorized into discrete depth ranges to build a coarse depth map. Based on this representation, we have explored the potential usefulness of our method in three application domains from novel viewpoints: camera rotation parameters estimation, background estimation and pedestrian candidate generation. In the first case, we have computed camera rotation mounted in a moving vehicle applying two novels methods based on distant elements in the image, where the translation component of the image flow vectors is negligible. In background estimation, we have proposed a novel method to reconstruct the background by penalizing close regions in a cost function, which integrates color, motion, and depth terms. Finally, we have benefited of geometric and depth information available on single images for pedestrian candidate generation to significantly reduce the number of generated windows to be further processed by a pedestrian classifier. In all cases, results have shown that our approaches contribute to better performances.

Abstract: This work aims at the automatic polyp detection by using a model of polyp appearance in the context of the analysis of colonoscopy videos. Our method consists of three stages: region segmentation, region description and region classification. The performance of our region segmentation method guarantees that if a polyp is present in the image, it will be exclusively and totally contained in a single region. The output of the algorithm also defines which regions can be considered as non-informative. We define as our region descriptor the novel Sector Accumulation-Depth of Valleys Accumulation (SA-DOVA), which provides a necessary but not sufficient condition for the polyp presence. Finally, we classify our segmented regions according to the maximal values of the SA-DOVA descriptor. Our preliminary classification results are promising, especially when classifying those parts of the image that do not contain a polyp inside.

Abstract: This work presents DGait, a new gait database acquired with a depth camera. This database contains videos from 53 subjects walking in different directions. The intent of this database is to provide a public set to explore whether the depth can be used as an additional information source for gait classification purposes. Each video is labelled according to subject, gender and age. Furthermore, for each subject and view point, we provide initial and final frames of an entire walk cycle. On the other hand, we perform gait-based gender classification experiments with DGait database, in order to illustrate the usefulness of depth information for this purpose. In our experiments, we extract 2D and 3D gait features based on shape descriptors, and compare the performance of these features for gender identification, using a Kernel SVM. The obtained results show that depth can be an information source of great relevance for gait classification problems.

Abstract: Dynamic Time Warping (DTW) is commonly used in gesture recognition tasks in order to tackle the temporal length variability of gestures. In the DTW framework, a set of gesture patterns are compared one by one to a maybe infinite test sequence, and a query gesture category is recognized if a warping cost below a certain threshold is found within the test sequence. Nevertheless, either taking one single sample per gesture category or a set of isolated samples may not encode the variability of such gesture category. In this paper, a probability-based DTW for gesture recognition is proposed. Different samples of the same gesture pattern obtained from RGB-Depth data are used to build a Gaussian-based probabilistic model of the gesture. Finally, the cost of DTW has been adapted accordingly to the new model. The proposed approach is tested in a challenging scenario, showing better performance of the probability-based DTW in comparison to state-of-the-art approaches for gesture recognition on RGB-D data.

Abstract: Automatic 3D reconstruction of human poses from monocular images is a challenging and popular topic in the computer vision community, which provides a wide range of applications in multiple areas. Solutions for 3D pose estimation involve various learning approaches, such as support vector machines and Gaussian processes, but many encounter difficulties in cluttered scenarios and require additional input data, such as silhouettes, or controlled camera settings. We present a framework that is capable of estimating the 3D pose of a person from single images or monocular image sequences without requiring background information and which is robust to camera variations. The framework models the non-linearity present in human pose estimation as it benefits from flexible learning approaches, including a highly customizable 2D detector. Results on the HumanEva benchmark show how they perform and influence the quality of the 3D pose estimates.

Abstract: Error-correcting output codes (ECOC) represents a powerful framework to deal with multiclass classification problems based on combining binary classifiers. The key factor affecting the performance of ECOC methods is the independence of binary classifiers, without which the ECOC method would be ineffective. In spite of its ability on classification of problems with relatively large number of classes, it has been applied in few real world problems. In this paper, we investigate the behavior of the ECOC approach on two image vision problems: logo recognition and shape classification using Decision Tree and AdaBoost as the base learners. The results show that the ECOC method can be used to improve the classification performance in comparison with the classical multiclass approaches.