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Aura Hernandez-Sabate, Debora Gil, David Roche, Monica M. S. Matsumoto, & Sergio S. Furuie. (2011). Inferring the Performance of Medical Imaging Algorithms. In Pedro Real, Daniel Diaz-Pernil, Helena Molina-Abril, Ainhoa Berciano, & Walter Kropatsch (Eds.), 14th International Conference on Computer Analysis of Images and Patterns (Vol. 6854, pp. 520–528). LNCS. Berlin: Springer-Verlag Berlin Heidelberg.
Abstract: Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence.
Keywords: Validation, Statistical Inference, Medical Imaging Algorithms.
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Gerard Lacey, & Fernando Vilariño. (2011). Endoscopy system with motion sensors.
Abstract: An endoscopy system (1) comprises an endoscope (2) with a camera (3) at its tip. The endoscope extends through an endoscope guide (4) for guiding movement of the endoscope and for measurement of its movement as it enters the body. The guide (4) comprises a generally conical body (5) having a through passage (105) through which the endoscope (2) extends. A motion sensor comprises an optical transmitter (7) and a detector (8) mounted alongside the passage (105) to measure the insertion-withdrawal linear motion and also rotation of the endoscope by the endoscopist's hand. The system (1) also comprises a flexure controller (10) having wheels operated by the endoscopist. The camera (3), the motion sensor (7/8), and the flexure controller (10) are all connected to a processor (11) which feeds a display.
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Patricia Marquez, Debora Gil, & Aura Hernandez-Sabate. (2011). A Confidence Measure for Assessing Optical Flow Accuracy in the Absence of Ground Truth. In IEEE International Conference on Computer Vision – Workshops (pp. 2042–2049). Barcelona (Spain): IEEE.
Abstract: Optical flow is a valuable tool for motion analysis in autonomous navigation systems. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in real world sequences. This paper introduces a measure of optical flow accuracy for Lucas-Kanade based flows in terms of the numerical stability of the data-term. We call this measure optical flow condition number. A statistical analysis over ground-truth data show a good statistical correlation between the condition number and optical flow error. Experiments on driving sequences illustrate its potential for autonomous navigation systems.
Keywords: IEEE International Conference on Computer Vision – Workshops
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Enric Marti, Ferran Poveda, Antoni Gurgui, & Debora Gil. (2011). Aprendizaje Basado en Proyectos en Ingeniería Informática. Resultados y reflexiones de seis años de experiencia.
Abstract: In this workshop a 6 years experience in Project Based Learning (PBL) in Computer Graphics, Computer Engineering course at the Autonomous University of Barcelona (UAB) is presented. We use a Moodle environment suited to manage the documentation generated in PBL. The course is organized by means of two alternative routes: a classic itinerary of lectures and test-based evaluation and another with PBL. In the PBL itinerary we explain the organization in teamgroups, homework tutoring and monitoring and evaluation guidelines for students. We provide some of the work done by students, and the results of assessment surveys carried out to students during these years. We report the evolution of our PBL itinerary in terms of, both, organization and student surveys.
The workshop aims at discussing about on the advantages and disadvantages of using these active methodologies in technical degrees such as computer engineering, in order to debate about the most suitable way of organizing PBL and assessing students learning rate.
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Joan M. Nuñez. (2011). Computer vision techniques for characterization of finger joints in X-ray image (Dr. Fernando Vilariño and Dra. Debora Gil, Ed.) (Vol. 165). Master's thesis, , .
Abstract: Rheumatoid arthritis (RA) is an autoimmune inflammatory type of arthritis which mainly affects hands on its first stages. Though it is a chronic disease and there is no cure for it, treatments require an accurate assessment of illness evolution. Such assessment is based on evaluation of hand X-ray images by using one of the several available semi-quantitative methods. This task requires highly trained medical personnel. That is why the automation of the assessment would allow professionals to save time and effort. Two stages are involved in this task. Firstly, the joint detection, afterwards, the joint characterization. Unlike the little existing previous work, this contribution clearly separates those two stages and sets the foundations of a modular assessment system focusing on the characterization stage. A hand joint dataset is created and an accurate data analysis is achieved in order to identify relevant features. Since the sclerosis and the lower bone were decided to be the most important features, different computer vision techniques were used in order to develop a detector system for both of them. Joint space width measures are provided and their correlation with Sharp-Van der Heijde is verified
Keywords: Rheumatoid arthritis, X-ray, Sharp Van der Heijde, joint characterization, sclerosis detection, bone detection, edge, ridge
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Ferran Poveda, Debora Gil, Albert Andaluz, & Enric Marti. (2011). Multiscale Tractography for Representing Heart Muscular Architecture. In In MICCAI 2011 Workshop on Computational Diffusion MRI.
Abstract: Deep understanding of myocardial structure of the heart would unravel crucial knowledge for clinical and medical procedures. Although the muscular architecture of the heart has been debated by countless researchers, the controversy is still alive. Diffusion Tensor MRI, DT-MRI, is a unique imaging technique for computational validation of the muscular structure of the heart. By the complex arrangement of myocites, existing techniques can not provide comprehensive descriptions of the global muscular architecture. In this paper we introduce a multiresolution reconstruction technique based on DT-MRI streamlining for simplified global myocardial model generation. Our reconstructions can restore the most complex myocardial structures and indicate a global helical organization
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David Roche, Debora Gil, & Jesus Giraldo. (2011). An inference model for analyzing termination conditions of Evolutionary Algorithms. In 14th Congrès Català en Intel·ligencia Artificial (pp. 216–225).
Abstract: In real-world problems, it is mandatory to design a termination condition for Evolutionary Algorithms (EAs) ensuring stabilization close to the unknown optimum. Distribution-based quantities are good candidates as far as suitable parameters are used. A main limitation for application to real-world problems is that such parameters strongly depend on the topology of the objective function, as well as, the EA paradigm used.
We claim that the termination problem would be fully solved if we had a model measuring to what extent a distribution-based quantity asymptotically behaves like the solution accuracy. We present a regression-prediction model that relates any two given quantities and reports if they can be statistically swapped as termination conditions. Our framework is applied to two issues. First, exploring if the parameters involved in the computation of distribution-based quantities influence their asymptotic behavior. Second, to what extent existing distribution-based quantities can be asymptotically exchanged for the accuracy of the EA solution.
Keywords: Evolutionary Computation Convergence, Termination Conditions, Statistical Inference
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David Roche, Debora Gil, & Jesus Giraldo. (2011). Using statistical inference for designing termination conditions ensuring convergence of Evolutionary Algorithms. In 11th European Conference on Artificial Life.
Abstract: A main challenge in Evolutionary Algorithms (EAs) is determining a termination condition ensuring stabilization close to the optimum in real-world applications. Although for known test functions distribution-based quantities are good candidates (as far as suitable parameters are used), in real-world problems an open question still remains unsolved. How can we estimate an upper-bound for the termination condition value ensuring a given accuracy for the (unknown) EA solution?
We claim that the termination problem would be fully solved if we defined a quantity (depending only on the EA output) behaving like the solution accuracy. The open question would be, then, satisfactorily answered if we had a model relating both quantities, since accuracy could be predicted from the alternative quantity. We present a statistical inference framework addressing two topics: checking the correlation between the two quantities and defining a regression model for predicting (at a given confidence level) accuracy values from the EA output.
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Carles Sanchez. (2011). Tracheal ring detection in bronchoscopy (F. J. S. Debora Gil, Ed.) (Vol. 168). Master's thesis, , .
Abstract: Endoscopy is the process in which a camera is introduced inside a human.
Given that endoscopy provides realistic images (in contrast to other modalities) and allows non-invase minimal intervention procedures (which can aid in diagnosis and surgical interventions), its use has spreaded during last decades.
In this project we will focus on bronchoscopic procedures, during which the camera is introduced through the trachea in order to have a diagnostic of the patient. The diagnostic interventions are focused on: degree of stenosis (reduction in tracheal area), prosthesis or early diagnosis of tumors. In the first case, assessment of the luminal area and the calculation of the diameters of the tracheal rings are required. A main limitation is that all the process is done by hand,
which means that the doctor takes all the measurements and decisions just by looking at the screen. As far as we know there is no computational framework for helping the doctors in the diagnosis.
This project will consist of analysing bronchoscopic videos in order to extract useful information for the diagnostic of the degree of stenosis. In particular we will focus on segmentation of the tracheal rings. As a result of this project several strategies (for detecting tracheal rings) had been implemented in order to compare their performance.
Keywords: Bronchoscopy, tracheal ring, segmentation
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Panagiota Spyridonos, Fernando Vilariño, Jordi Vitria, Petia Radeva, Fernando Azpiroz, & Juan Malagelada. (2011). Device, system and method for automatic detection of contractile activity in an image frame.
Abstract: A device, system and method for automatic detection of contractile activity of a body lumen in an image frame is provided, wherein image frames during contractile activity are captured and/or image frames including contractile activity are automatically detected, such as through pattern recognition and/or feature extraction to trace image frames including contractions, e.g., with wrinkle patterns. A manual procedure of annotation of contractions, e.g. tonic contractions in capsule endoscopy, may consist of the visualization of the whole video by a specialist, and the labeling of the contraction frames. Embodiments of the present invention may be suitable for implementation in an in vivo imaging system.
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Mariano Vazquez, Ruth Aris, Guillaume Hozeaux, R.Aubry, P.Villar, Jaume Garcia, et al. (2011). A massively parallel computational electrophysiology model of the heart. IJNMBE - International Journal for Numerical Methods in Biomedical Engineering, 27, 1911–1929.
Abstract: This paper presents a patient-sensitive simulation strategy capable of using the most efficient way the high-performance computational resources. The proposed strategy directly involves three different players: Computational Mechanics Scientists (CMS), Image Processing Scientists and Cardiologists, each one mastering its own expertise area within the project. This paper describes the general integrative scheme but focusing on the CMS side presents a massively parallel implementation of computational electrophysiology applied to cardiac tissue simulation. The paper covers different angles of the computational problem: equations, numerical issues, the algorithm and parallel implementation. The proposed methodology is illustrated with numerical simulations testing all the different possibilities, ranging from small domains up to very large ones. A key issue is the almost ideal scalability not only for large and complex problems but also for medium-size meshes. The explicit formulation is particularly well suited for solving this highly transient problems, with very short time-scale.
Keywords: computational electrophysiology; parallelization; finite element methods
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Naveen Onkarappa, & Angel Sappa. (2011). Space Variant Representations for Mobile Platform Vision Applications. In W. Kropatsch A. Berciano H. Molina D. D. P. Real (Ed.), 14th International Conference on Computer Analysis of Images and Patterns (Vol. 6855, pp. 146–154). Springer Berlin Heidelberg.
Abstract: The log-polar space variant representation, motivated by biological vision, has been widely studied in the literature. Its data reduction and invariance properties made it useful in many vision applications. However, due to its nature, it fails in preserving features in the periphery. In the current work, as an attempt to overcome this problem, we propose a novel space-variant representation. It is evaluated and proved to be better than the log-polar representation in preserving the peripheral information, crucial for on-board mobile vision applications. The evaluation is performed by comparing log-polar and the proposed representation once they are used for estimating dense optical flow.
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Sergio Vera, Debora Gil, Agnes Borras, F. Javier Sanchez, Frederic Perez, & Marius G. Linguraru. (2011). Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs. In In H. Yoshida et al (Ed.), Workshop on Computational and Clinical Applications in Abdominal Imaging (Vol. 7029, pp. 223–230). Springer Berlin Heidelberg.
Abstract: Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.
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