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Author |
Sergio Vera; Debora Gil; Antonio Lopez; Miguel Angel Gonzalez Ballester |
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Title |
Multilocal Creaseness Measure |
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Journal |
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Year |
2012 |
Publication |
The Insight Journal |
Abbreviated Journal |
IJ |
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Keywords |
Ridges, Valley, Creaseness, Structure Tensor, Skeleton, |
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Abstract |
This document describes the implementation using the Insight Toolkit of an algorithm for detecting creases (ridges and valleys) in N-dimensional images, based on the Local Structure Tensor of the image. In addition to the filter used to calculate the creaseness image, a filter for the computation of the structure tensor is also included in this submission. |
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Alma IT Systems |
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english |
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english |
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IAM;ADAS; |
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IAM @ iam @ VGL2012 |
Serial |
1840 |
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Author |
Sergio Vera; Debora Gil; Agnes Borras; Marius George Linguraru; Miguel Angel Gonzalez Ballester |
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Title |
Geometric Steerable Medial Maps |
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Journal Article |
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Year |
2013 |
Publication |
Machine Vision and Applications |
Abbreviated Journal |
MVA |
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Volume |
24 |
Issue |
6 |
Pages |
1255-1266 |
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Keywords |
Medial Representations ,Medial Manifolds Comparation , Surface , Reconstruction |
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Abstract |
In order to provide more intuitive and easily interpretable representations of complex shapes/organs, medial manifolds should reach a compromise between simplicity in geometry and capability for restoring the anatomy/shape of the organ/volume. Existing morphological methods show excellent results when applied to 2D objects, but their quality drops across dimensions.
This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoids degenerated medial axis segments. Second, we introduce a continuous operator for accurate and efficient computation of medial structures of arbitrary dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to syn- thetic shapes of known medial geometry. We also show its higher performance for medical imaging applications in terms of simplicity of medial structures and capability for reconstructing the anatomical volume. |
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Springer Berlin Heidelberg |
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Mubarak Shah |
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0932-8092 |
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IAM; 605.203; 600.060; 600.044 |
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IAM @ iam @ VGB2013 |
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2192 |
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Author |
Ernest Valveny; Enric Marti |
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Title |
A model for image generation and symbol recognition through the deformation of lineal shapes |
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Journal Article |
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Year |
2003 |
Publication |
Pattern Recognition Letters |
Abbreviated Journal |
PRL |
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Volume |
24 |
Issue |
15 |
Pages |
2857-2867 |
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We describe a general framework for the recognition of distorted images of lineal shapes, which relies on three items: a model to represent lineal shapes and their deformations, a model for the generation of distorted binary images and the combination of both models in a common probabilistic framework, where the generation of deformations is related to an internal energy, and the generation of binary images to an external energy. Then, recognition consists in the minimization of a global energy function, performed by using the EM algorithm. This general framework has been applied to the recognition of hand-drawn lineal symbols in graphic documents. |
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Elsevier Science Inc. |
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New York, NY, USA |
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0167-8655 |
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DAG; IAM |
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IAM @ iam @ VAM2003 |
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1653 |
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Author |
Mariano Vazquez; Ruth Aris; Guillaume Hozeaux; R.Aubry; P.Villar;Jaume Garcia ; Debora Gil; Francesc Carreras |
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Title |
A massively parallel computational electrophysiology model of the heart |
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Journal Article |
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Year |
2011 |
Publication |
International Journal for Numerical Methods in Biomedical Engineering |
Abbreviated Journal |
IJNMBE |
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Volume |
27 |
Issue |
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Pages |
1911-1929 |
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Keywords |
computational electrophysiology; parallelization; finite element methods |
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This paper presents a patient-sensitive simulation strategy capable of using the most efficient way the high-performance computational resources. The proposed strategy directly involves three different players: Computational Mechanics Scientists (CMS), Image Processing Scientists and Cardiologists, each one mastering its own expertise area within the project. This paper describes the general integrative scheme but focusing on the CMS side presents a massively parallel implementation of computational electrophysiology applied to cardiac tissue simulation. The paper covers different angles of the computational problem: equations, numerical issues, the algorithm and parallel implementation. The proposed methodology is illustrated with numerical simulations testing all the different possibilities, ranging from small domains up to very large ones. A key issue is the almost ideal scalability not only for large and complex problems but also for medium-size meshes. The explicit formulation is particularly well suited for solving this highly transient problems, with very short time-scale. |
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Swansea (UK) |
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John Wiley & Sons, Ltd. |
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John Wiley & Sons, Ltd. |
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IAM |
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IAM @ iam @ VAH2011 |
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1198 |
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Author |
Misael Rosales; Petia Radeva;Oriol Rodriguez-Leon; Debora Gil |
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Title |
Modelling of image-catheter motion for 3-D IVUS |
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Journal Article |
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Year |
2009 |
Publication |
Medical image analysis |
Abbreviated Journal |
MIA |
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Volume |
13 |
Issue |
1 |
Pages |
91-104 |
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Keywords |
Intravascular ultrasound (IVUS); Motion estimation; Motion decomposition; Fourier |
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Abstract |
Three-dimensional intravascular ultrasound (IVUS) allows to visualize and obtain volumetric measurements of coronary lesions through an exploration of the cross sections and longitudinal views of arteries. However, the visualization and subsequent morpho-geometric measurements in IVUS longitudinal cuts are subject to distortion caused by periodic image/vessel motion around the IVUS catheter. Usually, to overcome the image motion artifact ECG-gating and image-gated approaches are proposed, leading to slowing the pullback acquisition or disregarding part of IVUS data. In this paper, we argue that the image motion is due to 3-D vessel geometry as well as cardiac dynamics, and propose a dynamic model based on the tracking of an elliptical vessel approximation to recover the rigid transformation and align IVUS images without loosing any IVUS data. We report an extensive validation with synthetic simulated data and in vivo IVUS sequences of 30 patients achieving an average reduction of the image artifact of 97% in synthetic data and 79% in real-data. Our study shows that IVUS alignment improves longitudinal analysis of the IVUS data and is a necessary step towards accurate reconstruction and volumetric measurements of 3-D IVUS. |
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IAM;MILAB |
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IAM @ iam @ RRR2009 |
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1646 |
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Author |
David Rotger; Misael Rosales; Jaume Garcia; Oriol Pujol ; Josefina Mauri; Petia Radeva |
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Title |
Active Vessel: A New Multimedia Workstation for Intravascular Ultrasound and Angiography Fusion |
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Journal Article |
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Year |
2003 |
Publication |
Computers in Cardiology |
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30 |
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65-68 |
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Abstract |
AcriveVessel is a new multimedia workstation which enables the visualization, acquisition and handling of both image modalities, on- and ofline. It enables DICOM v3.0 decompression and browsing, video acquisition,repmduction and storage for IntraVascular UltraSound (IVUS) and angiograms with their corresponding ECG,automatic catheter segmentation in angiography images (using fast marching algorithm). BSpline models definition for vessel layers on IVUS images sequence and an extensively validated tool to fuse information. This approach defines the correspondence of every IVUS image with its correspondent point in the angiogram and viceversa. The 3 0 reconstruction of the NUS catheterhessel enables real distance measurements as well as threedimensional visualization showing vessel tortuosity in the space. |
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IAM;MILAB;HuPBA |
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IAM @ iam @ RRG2003 |
Serial |
1647 |
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Author |
Oriol Rodriguez-Leon; Josefina Mauri;Eduard Fernandez-Nofrerias; Antonio Tovar; Vicente del Valle; Aura Hernandez-Sabate; Debora Gil; Petia Radeva |
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Title |
Utilización de la Estructura de los Campos Vectoriales para la Detección de la Adventicia en Imágenes de Ecografía Intracoronaria |
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Journal Article |
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2004 |
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Revista Internacional de Enfermedades Cardiovasculares Revista Española de Cardiología |
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57 |
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2 |
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100 |
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IAM;MILAB |
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IAM @ iam @ RMF2004 |
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1642 |
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Author |
Oriol Rodriguez-Leon; Josefina Mauri;Eduard Fernandez-Nofrerias; C.Garcia; R.Villuendas; Vicente del Valle; Debora Gil;Petia Radeva |
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Reconstruction of a spatio-temporal model of the intima layer from intravascular ultrasound sequences |
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2003 |
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European Heart Journal |
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ESC Congress |
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IAM;MILAB |
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IAM @ iam @ RMF2003c |
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1641 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Mechanistic analysis of the function of agonists and allosteric modulators: Reconciling two-state and operational models |
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Journal Article |
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2013 |
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British Journal of Pharmacology |
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BJP |
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169 |
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6 |
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1189-202 |
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Two-state and operational models of both agonism and allosterism are compared to identify and characterize common pharmacological parameters. To account for the receptor-dependent basal response, constitutive receptor activity is considered in the operational models. By arranging two-state models as the fraction of active receptors and operational models as the fractional response relative to the maximum effect of the system, a one-by-one correspondence between parameters is found. The comparative analysis allows a better understanding of complex allosteric interactions. In particular, the inclusion of constitutive receptor activity in the operational model of allosterism allows the characterization of modulators able to lower the basal response of the system; that is, allosteric modulators with negative intrinsic efficacy. Theoretical simulations and overall goodness of fit of the models to simulated data suggest that it is feasible to apply the models to experimental data and constitute one step forward in receptor theory formalism. |
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IAM; 600.044; 605.203 |
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IAM @ iam @ RGG2013b |
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2195 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Multiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism, |
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Journal Article |
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2013 |
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Drug Discovery Today |
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DDT |
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18 |
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7-8 |
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365-371 |
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The operational model of agonism assumes that the maximum effect a particular receptor system can achieve (the Em parameter) is fixed. Em estimates are above but close to the asymptotic maximum effects of endogenous agonists. The concept of Em is contradicted by superagonists and those positive allosteric modulators that significantly increase the maximum effect of endogenous agonists. An extension of the operational model is proposed that assumes that the Em parameter does not necessarily have a single value for a receptor system but has multiple values associated to multiple active receptor conformations. The model provides a mechanistic link between active receptor conformation and agonist efficacy, which can be useful for the analysis of agonist response under different receptor scenarios. |
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Elsevier |
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IAM; 600.057; 600.054 |
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IAM @ iam @ RGG2013a |
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2190 |
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