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Mireia Sole; Joan Blanco; Debora Gil; Oliver Valero; G. Fonseka; M. Lawrie; Francesca Vidal; Zaida Sarrate |
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Title |
Chromosome Territories in Mice Spermatogenesis: A new three-dimensional methodology of study |
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Conference Article |
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2017 |
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11th European CytoGenesis Conference |
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Florencia; Italia; July 2017 |
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ECA |
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IAM; 600.096; 600.145 |
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Admin @ si @ SBG2017a |
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2936 |
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Author |
Carles Sanchez; Debora Gil; T. Gache; N. Koufos; Marta Diez-Ferrer; Antoni Rosell |
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SENSA: a System for Endoscopic Stenosis Assessment |
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2016 |
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28th Conference of the international Society for Medical Innovation and Technology |
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Documenting the severity of a static or dynamic Central Airway Obstruction (CAO) is crucial to establish proper diagnosis and treatment, predict possible treatment effects and better follow-up the patients. The subjective visual evaluation of a stenosis during video-bronchoscopy still remains the most common way to assess a CAO in spite of a consensus among experts for a need to standardize all calculations [1].
The Computer Vision Center in cooperation with the «Hospital de Bellvitge», has developed a System for Endoscopic Stenosis Assessment (SENSA), which computes CAO directly by analyzing standard bronchoscopic data without the need of using other imaging tecnologies. |
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Rotterdam; The Netherlands; October 2016 |
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SMIT |
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IAM; |
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Admin @ si @ SGG2016 |
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2942 |
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Author |
Carles Sanchez; Antonio Esteban Lansaque; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil |
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Towards a Videobronchoscopy Localization System from Airway Centre Tracking |
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2017 |
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12th International Conference on Computer Vision Theory and Applications |
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352-359 |
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Video-bronchoscopy; Lung cancer diagnosis; Airway lumen detection; Region tracking; Guided bronchoscopy navigation |
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Bronchoscopists use fluoroscopy to guide flexible bronchoscopy to the lesion to be biopsied without any kind of incision. Being fluoroscopy an imaging technique based on X-rays, the risk of developmental problems and cancer is increased in those subjects exposed to its application, so minimizing radiation is crucial. Alternative guiding systems such as electromagnetic navigation require specific equipment, increase the cost of the clinical procedure and still require fluoroscopy. In this paper we propose an image based guiding system based on the extraction of airway centres from intra-operative videos. Such anatomical landmarks are matched to the airway centreline extracted from a pre-planned CT to indicate the best path to the nodule. We present a
feasibility study of our navigation system using simulated bronchoscopic videos and a multi-expert validation of landmarks extraction in 3 intra-operative ultrathin explorations. |
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Porto; Portugal; February 2017 |
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VISAPP |
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IAM; 600.096; 600.075; 600.145 |
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Admin @ si @ SEB2017 |
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2943 |
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Author |
Debora Gil; Oriol Ramos Terrades; Elisa Minchole; Carles Sanchez; Noelia Cubero de Frutos; Marta Diez-Ferrer; Rosa Maria Ortiz; Antoni Rosell |
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Title |
Classification of Confocal Endomicroscopy Patterns for Diagnosis of Lung Cancer |
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Conference Article |
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2017 |
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6th Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging |
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10550 |
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151-159 |
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Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy.
The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%.
We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results. |
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Quebec; Canada; September 2017 |
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CLIP |
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IAM; 600.096; 600.075; 600.145;DAG |
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Admin @ si @ GRM2017 |
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2957 |
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Author |
Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Oliver Valero; Francesca Vidal; Zaida Sarrate |
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Title |
Is there a pattern of Chromosome territoriality along mice spermatogenesis? |
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2017 |
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3rd Spanish MeioNet Meeting Abstract Book |
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55-56 |
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Miraflores de la Sierra; Madrid; June 2017 |
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MEIONET |
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IAM; 600.096; 600.145 |
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Admin @ si @ |
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2958 |
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Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Oliver Valero; Francesca Vidal; Zaida Sarrate |
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Title |
Unraveling the enigmas of chromosome territoriality during spermatogenesis |
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2017 |
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IX Jornada del Departament de Biologia Cel•lular, Fisiologia i Immunologia |
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UAB; Barcelona; June 2017 |
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IAM; 600.145 |
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Admin @ si @ SBG2017b |
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2959 |
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Author |
Rosa Maria Ortiz; Debora Gil; Elisa Minchole; Marta Diez-Ferrer; Noelia Cubero de Frutos |
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Title |
Classification of Confolcal Endomicroscopy Patterns for Diagnosis of Lung Cancer |
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2017 |
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18th World Conference on Lung Cancer |
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Abstract |
Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy.
The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%.
We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results. |
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Yokohama; Japan; October 2017 |
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IASLC WCLC |
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IAM; 600.096; 600.075; 600.145 |
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Admin @ si @ OGM2017 |
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3044 |
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Debora Gil; Aura Hernandez-Sabate; David Castells; Jordi Carrabina |
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CYBERH: Cyber-Physical Systems in Health for Personalized Assistance |
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2017 |
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International Symposium on Symbolic and Numeric Algorithms for Scientific Computing |
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Assistance systems for e-Health applications have some specific requirements that demand of new methods for data gathering, analysis and modeling able to deal with SmallData:
1) systems should dynamically collect data from, both, the environment and the user to issue personalized recommendations; 2) data analysis should be able to tackle a limited number of samples prone to include non-informative data and possibly evolving in time due to changes in patient condition; 3) algorithms should run in real time with possibly limited computational resources and fluctuant internet access.
Electronic medical devices (and CyberPhysical devices in general) can enhance the process of data gathering and analysis in several ways: (i) acquiring simultaneously multiple sensors data instead of single magnitudes (ii) filtering data; (iii) providing real-time implementations condition by isolating tasks in individual processors of multiprocessors Systems-on-chip (MPSoC) platforms and (iv) combining information through sensor fusion
techniques.
Our approach focus on both aspects of the complementary role of CyberPhysical devices and analysis of SmallData in the process of personalized models building for e-Health applications. In particular, we will address the design of Cyber-Physical Systems in Health for Personalized Assistance (CyberHealth) in two specific application cases: 1) A Smart Assisted Driving System (SADs) for dynamical assessment of the driving capabilities of Mild Cognitive Impaired (MCI) people; 2) An Intelligent Operating Room (iOR) for improving the yield of bronchoscopic interventions for in-vivo lung cancer diagnosis. |
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Timisoara; Rumania; September 2017 |
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SYNASC |
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IAM; 600.085; 600.096; 600.075; 600.145 |
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Admin @ si @ GHC2017 |
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3045 |
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Author |
Esmitt Ramirez; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil |
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Title |
Image-Based Bronchial Anatomy Codification for Biopsy Guiding in Video Bronchoscopy |
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2018 |
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OR 2.0 Context-Aware Operating Theaters, Computer Assisted Robotic Endoscopy, Clinical Image-Based Procedures, and Skin Image Analysis |
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11041 |
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Biopsy guiding; Bronchoscopy; Lung biopsy; Intervention guiding; Airway codification |
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Bronchoscopy examinations allow biopsy of pulmonary nodules with minimum risk for the patient. Even for experienced bronchoscopists, it is difficult to guide the bronchoscope to most distal lesions and obtain an accurate diagnosis. This paper presents an image-based codification of the bronchial anatomy for bronchoscopy biopsy guiding. The 3D anatomy of each patient is codified as a binary tree with nodes representing bronchial levels and edges labeled using their position on images projecting the 3D anatomy from a set of branching points. The paths from the root to leaves provide a codification of navigation routes with spatially consistent labels according to the anatomy observes in video bronchoscopy explorations. We evaluate our labeling approach as a guiding system in terms of the number of bronchial levels correctly codified, also in the number of labels-based instructions correctly supplied, using generalized mixed models and computer-generated data. Results obtained for three independent observers prove the consistency and reproducibility of our guiding system. We trust that our codification based on viewer’s projection might be used as a foundation for the navigation process in Virtual Bronchoscopy systems. |
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Granada; September 2018 |
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MICCAIW |
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IAM; 600.096; 600.075; 601.323; 600.145 |
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Admin @ si @ RSB2018b |
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3137 |
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Author |
Santi Puch; Irina Sanchez; Aura Hernandez-Sabate; Gemma Piella; Vesna Prckovska |
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Title |
Global Planar Convolutions for Improved Context Aggregation in Brain Tumor Segmentation |
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2018 |
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International MICCAI Brainlesion Workshop |
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11384 |
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393-405 |
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Brain tumors; 3D fully-convolutional CNN; Magnetic resonance imaging; Global planar convolution |
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In this work, we introduce the Global Planar Convolution module as a building-block for fully-convolutional networks that aggregates global information and, therefore, enhances the context perception capabilities of segmentation networks in the context of brain tumor segmentation. We implement two baseline architectures (3D UNet and a residual version of 3D UNet, ResUNet) and present a novel architecture based on these two architectures, ContextNet, that includes the proposed Global Planar Convolution module. We show that the addition of such module eliminates the need of building networks with several representation levels, which tend to be over-parametrized and to showcase slow rates of convergence. Furthermore, we provide a visual demonstration of the behavior of GPC modules via visualization of intermediate representations. We finally participate in the 2018 edition of the BraTS challenge with our best performing models, that are based on ContextNet, and report the evaluation scores on the validation and the test sets of the challenge. |
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MICCAIW |
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ADAS; 600.118;IAM |
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Admin @ si @ PSH2018 |
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3251 |
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