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Debora Gil; Aura Hernandez-Sabate; David Castells; Jordi Carrabina |
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Title |
CYBERH: Cyber-Physical Systems in Health for Personalized Assistance |
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2017 |
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International Symposium on Symbolic and Numeric Algorithms for Scientific Computing |
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Assistance systems for e-Health applications have some specific requirements that demand of new methods for data gathering, analysis and modeling able to deal with SmallData:
1) systems should dynamically collect data from, both, the environment and the user to issue personalized recommendations; 2) data analysis should be able to tackle a limited number of samples prone to include non-informative data and possibly evolving in time due to changes in patient condition; 3) algorithms should run in real time with possibly limited computational resources and fluctuant internet access.
Electronic medical devices (and CyberPhysical devices in general) can enhance the process of data gathering and analysis in several ways: (i) acquiring simultaneously multiple sensors data instead of single magnitudes (ii) filtering data; (iii) providing real-time implementations condition by isolating tasks in individual processors of multiprocessors Systems-on-chip (MPSoC) platforms and (iv) combining information through sensor fusion
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Our approach focus on both aspects of the complementary role of CyberPhysical devices and analysis of SmallData in the process of personalized models building for e-Health applications. In particular, we will address the design of Cyber-Physical Systems in Health for Personalized Assistance (CyberHealth) in two specific application cases: 1) A Smart Assisted Driving System (SADs) for dynamical assessment of the driving capabilities of Mild Cognitive Impaired (MCI) people; 2) An Intelligent Operating Room (iOR) for improving the yield of bronchoscopic interventions for in-vivo lung cancer diagnosis. |
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Timisoara; Rumania; September 2017 |
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IAM; 600.085; 600.096; 600.075; 600.145 |
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Admin @ si @ GHC2017 |
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3045 |
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Author |
Esmitt Ramirez; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil |
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Title |
Image-Based Bronchial Anatomy Codification for Biopsy Guiding in Video Bronchoscopy |
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2018 |
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OR 2.0 Context-Aware Operating Theaters, Computer Assisted Robotic Endoscopy, Clinical Image-Based Procedures, and Skin Image Analysis |
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11041 |
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Biopsy guiding; Bronchoscopy; Lung biopsy; Intervention guiding; Airway codification |
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Bronchoscopy examinations allow biopsy of pulmonary nodules with minimum risk for the patient. Even for experienced bronchoscopists, it is difficult to guide the bronchoscope to most distal lesions and obtain an accurate diagnosis. This paper presents an image-based codification of the bronchial anatomy for bronchoscopy biopsy guiding. The 3D anatomy of each patient is codified as a binary tree with nodes representing bronchial levels and edges labeled using their position on images projecting the 3D anatomy from a set of branching points. The paths from the root to leaves provide a codification of navigation routes with spatially consistent labels according to the anatomy observes in video bronchoscopy explorations. We evaluate our labeling approach as a guiding system in terms of the number of bronchial levels correctly codified, also in the number of labels-based instructions correctly supplied, using generalized mixed models and computer-generated data. Results obtained for three independent observers prove the consistency and reproducibility of our guiding system. We trust that our codification based on viewer’s projection might be used as a foundation for the navigation process in Virtual Bronchoscopy systems. |
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Granada; September 2018 |
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MICCAIW |
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IAM; 600.096; 600.075; 601.323; 600.145 |
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Admin @ si @ RSB2018b |
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3137 |
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Santi Puch; Irina Sanchez; Aura Hernandez-Sabate; Gemma Piella; Vesna Prckovska |
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Global Planar Convolutions for Improved Context Aggregation in Brain Tumor Segmentation |
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2018 |
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International MICCAI Brainlesion Workshop |
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11384 |
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393-405 |
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Brain tumors; 3D fully-convolutional CNN; Magnetic resonance imaging; Global planar convolution |
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In this work, we introduce the Global Planar Convolution module as a building-block for fully-convolutional networks that aggregates global information and, therefore, enhances the context perception capabilities of segmentation networks in the context of brain tumor segmentation. We implement two baseline architectures (3D UNet and a residual version of 3D UNet, ResUNet) and present a novel architecture based on these two architectures, ContextNet, that includes the proposed Global Planar Convolution module. We show that the addition of such module eliminates the need of building networks with several representation levels, which tend to be over-parametrized and to showcase slow rates of convergence. Furthermore, we provide a visual demonstration of the behavior of GPC modules via visualization of intermediate representations. We finally participate in the 2018 edition of the BraTS challenge with our best performing models, that are based on ContextNet, and report the evaluation scores on the validation and the test sets of the challenge. |
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MICCAIW |
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ADAS; 600.118;IAM |
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Admin @ si @ PSH2018 |
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3251 |
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Marta Ligero; Guillermo Torres; Carles Sanchez; Katerine Diaz; Raquel Perez; Debora Gil |
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Title |
Selection of Radiomics Features based on their Reproducibility |
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2019 |
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41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
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403-408 |
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Dimensionality reduction is key to alleviate machine learning artifacts in clinical applications with Small Sample Size (SSS) unbalanced datasets. Existing methods rely on either the probabilistic distribution of training data or the discriminant power of the reduced space, disregarding the impact of repeatability and uncertainty in features.In the present study is proposed the use of reproducibility of radiomics features to select features with high inter-class correlation coefficient (ICC). The reproducibility includes the variability introduced in the image acquisition, like medical scans acquisition parameters and convolution kernels, that affects intensity-based features and tumor annotations made by physicians, that influences morphological descriptors of the lesion.For the reproducibility of radiomics features three studies were conducted on cases collected at Vall Hebron Oncology Institute (VHIO) on responders to oncology treatment. The studies focused on the variability due to the convolution kernel, image acquisition parameters, and the inter-observer lesion identification. The features selected were those features with a ICC higher than 0.7 in the three studies.The selected features based on reproducibility were evaluated for lesion malignancy classification using a different database. Results show better performance compared to several state-of-the-art methods including Principal Component Analysis (PCA), Kernel Discriminant Analysis via QR decomposition (KDAQR), LASSO, and an own built Convolutional Neural Network. |
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Berlin; Alemanya; July 2019 |
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EMBC |
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IAM; 600.139; 600.145 |
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Admin @ si @ LTS2019 |
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3358 |
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Author |
Debora Gil; Antonio Esteban Lansaque; Sebastian Stefaniga; Mihail Gaianu; Carles Sanchez |
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Title |
Data Augmentation from Sketch |
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Conference Article |
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2019 |
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International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging |
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11840 |
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155-162 |
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Data augmentation; cycleGANs; Multi-objective optimization |
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State of the art machine learning methods need huge amounts of data with unambiguous annotations for their training. In the context of medical imaging this is, in general, a very difficult task due to limited access to clinical data, the time required for manual annotations and variability across experts. Simulated data could serve for data augmentation provided that its appearance was comparable to the actual appearance of intra-operative acquisitions. Generative Adversarial Networks (GANs) are a powerful tool for artistic style transfer, but lack a criteria for selecting epochs ensuring also preservation of intra-operative content.
We propose a multi-objective optimization strategy for a selection of cycleGAN epochs ensuring a mapping between virtual images and the intra-operative domain preserving anatomical content. Our approach has been applied to simulate intra-operative bronchoscopic videos and chest CT scans from virtual sketches generated using simple graphical primitives. |
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Shenzhen; China; October 2019 |
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CLIP |
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IAM; 600.145; 601.337; 600.139; 600.145 |
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Admin @ si @ GES2019 |
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3359 |
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Author |
Carles Sanchez; Miguel Viñas; Coen Antens; Agnes Borras; Debora Gil |
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Back to Front Architecture for Diagnosis as a Service |
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2018 |
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20th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing |
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343-346 |
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Software as a Service (SaaS) is a cloud computing model in which a provider hosts applications in a server that customers use via internet. Since SaaS does not require to install applications on customers' own computers, it allows the use by multiple users of highly specialized software without extra expenses for hardware acquisition or licensing. A SaaS tailored for clinical needs not only would alleviate licensing costs, but also would facilitate easy access to new methods for diagnosis assistance. This paper presents a SaaS client-server architecture for Diagnosis as a Service (DaaS). The server is based on docker technology in order to allow execution of softwares implemented in different languages with the highest portability and scalability. The client is a content management system allowing the design of websites with multimedia content and interactive visualization of results allowing user editing. We explain a usage case that uses our DaaS as crowdsourcing platform in a multicentric pilot study carried out to evaluate the clinical benefits of a software for assessment of central airway obstruction. |
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Timisoara; Rumania; September 2018 |
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IAM; 600.145 |
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Admin @ si @ SVA2018 |
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3360 |
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Author |
Debora Gil; Guillermo Torres |
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A multi-shape loss function with adaptive class balancing for the segmentation of lung structures |
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2020 |
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34th International Congress and Exhibition on Computer Assisted Radiology & Surgery |
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Virtual; June 2020 |
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CARS |
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IAM; 600.139; 600.145 |
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Admin @ si @ GiT2020 |
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3472 |
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Debora Gil; Oriol Ramos Terrades; Raquel Perez |
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Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution |
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2020 |
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Women in Geometry and Topology |
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Barcelona; September 2019 |
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IAM; DAG; 600.139; 600.145; 600.121 |
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Admin @ si @ GRP2020 |
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3473 |
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Esmitt Ramirez; Carles Sanchez; Debora Gil |
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Localizing Pulmonary Lesions Using Fuzzy Deep Learning |
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2019 |
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21st International Symposium on Symbolic and Numeric Algorithms for Scientific Computing |
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290-294 |
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The usage of medical images is part of the clinical daily in several healthcare centers around the world. Particularly, Computer Tomography (CT) images are an important key in the early detection of suspicious lung lesions. The CT image exploration allows the detection of lung lesions before any invasive procedure (e.g. bronchoscopy, biopsy). The effective localization of lesions is performed using different image processing and computer vision techniques. Lately, the usage of deep learning models into medical imaging from detection to prediction shown that is a powerful tool for Computer-aided software. In this paper, we present an approach to localize pulmonary lung lesion using fuzzy deep learning. Our approach uses a simple convolutional neural network based using the LIDC-IDRI dataset. Each image is divided into patches associated a probability vector (fuzzy) according their belonging to anatomical structures on a CT. We showcase our approach as part of a full CAD system to exploration, planning, guiding and detection of pulmonary lesions. |
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Timisoara; Rumania; September 2019 |
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IAM; 600.145; 600.140; 601.337; 601.323 |
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Admin @ si @ RSG2019 |
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3531 |
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Author |
Jose Elias Yauri; Aura Hernandez-Sabate; Pau Folch; Debora Gil |
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Mental Workload Detection Based on EEG Analysis |
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2021 |
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Artificial Intelligent Research and Development. Proceedings 23rd International Conference of the Catalan Association for Artificial Intelligence. |
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339 |
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268-277 |
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Cognitive states; Mental workload; EEG analysis; Neural Networks. |
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The study of mental workload becomes essential for human work efficiency, health conditions and to avoid accidents, since workload compromises both performance and awareness. Although workload has been widely studied using several physiological measures, minimising the sensor network as much as possible remains both a challenge and a requirement.
Electroencephalogram (EEG) signals have shown a high correlation to specific cognitive and mental states like workload. However, there is not enough evidence in the literature to validate how well models generalize in case of new subjects performing tasks of a workload similar to the ones included during model’s training.
In this paper we propose a binary neural network to classify EEG features across different mental workloads. Two workloads, low and medium, are induced using two variants of the N-Back Test. The proposed model was validated in a dataset collected from 16 subjects and shown a high level of generalization capability: model reported an average recall of 81.81% in a leave-one-out subject evaluation. |
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Virtual; October 20-22 2021 |
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CCIA |
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IAM; 600.139; 600.118; 600.145 |
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Admin @ si @ |
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3723 |
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