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Jaume Garcia; Debora Gil; A.Bajo; M.J.Ledesma-Carbayo; C.SantaMarta |
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Influence of the temporal resolution on the quantification of displacement fields in cardiac magnetic resonance tagged images |
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Conference Article |
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2008 |
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Proc. Computers in Cardiology |
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35 |
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785-788 |
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It is difficult to acquire tagged cardiac MR images with a high temporal and spatial resolution using clinical MR scanners. However, if such images are used for quantifying scores based on motion, it is essential a resolution as high as possible. This paper explores the influence of the temporal resolution of a tagged series on the quantification of myocardial dynamic parameters. To such purpose we have designed a SPAMM (Spatial Modulation of Magnetization) sequence allowing acquisition of sequences at simple and double temporal resolution. Sequences are processed to compute myocardial motion by an automatic technique based on the tracking of the harmonic phase of tagged images (the Harmonic Phase Flow, HPF). The results have been compared to manual tracking of myocardial tags. The error in displacement fields for double resolution sequences reduces 17%. |
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Alan Murray |
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IAM @ iam @ GGB2008 |
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1508 |
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Jaume Garcia; Debora Gil; Joel Barajas; Francesc Carreras; Sandra Pujades; Petia Radeva |
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Title |
Characterization of ventricular torsion in healthy subjects using Gabor filters and a variational framework |
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2006 |
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Proc. Computers in Cardiology |
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877-880 |
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In this work, we present a fully automated method for tissue deformation estimation in tagged magnetic resonance images (TMRI). Gabor filter banks, tuned independently for each left ventricle level, provide optimally filtered complex images which phase remains constant along the cardiac cycle. This fact can be thought as the brightness constancy condition required by classical optical flow (OF) methods. Pairs of these filtered sequences, together with a variational formulation are used in a second step to obtain dense continuous deformation maps that we call Harmonic Phase Flow. This method has been used to determine reference values of ventricular torsion (VT) in a set of 8 healthy volunteers. The results encourage the use of VT as a useful parameter for ventricular function assessment in clinical routine. |
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IAM;MILAB |
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IAM @ iam @ GGB2006a |
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1509 |
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Jaume Garcia; Francesc Carreras; Sandra Pujades; Debora Gil |
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Title |
Regional motion patterns for the Left Ventricle function assessment |
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Conference Article |
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2008 |
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Proc. 19th Int. Conf. Pattern Recognition ICPR 2008 |
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1-4 |
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Regional scores (e.g. strain, perfusion) of the Left Ventricle (LV) functionality are playing an increasing role in the diagnosis of cardiac diseases. A main limitation is the lack of normality models for complementary scores oriented to assessment of the LV integrity. This paper introduces an original framework based on a parametrization of the LV domain, which allows comparison across subjects of local physiological measures of different nature. We compute regional normality patterns in a feature space characterizing the LV function. We show the consistency of the model for the regional motion on healthy and hypokinetic pathological cases |
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IAM @ iam @ GCP2008 |
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1510 |
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Jaume Garcia; David Rotger; Francesc Carreras; R.Leta; Petia Radeva |
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Contrast echography segmentation and tracking by trained deformable models |
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2003 |
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Proc. Computers in Cardiology |
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30 |
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173-176 |
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The objective of this work is to segment the human left ventricle myocardium (LVM) in contrast echocardiography imaging and thus track it along a cardiac cycle in order to extract quantitative data about heart function. Ultrasound images are hard to work with due to their speckle appearance. To overcome this we report the combination of active contour models (ACM) or snakes and active shape models (ASM). The ability of ACM in giving closed and smooth curves in addition to the power of the ASM in producing shapes similar to the ones learned, evoke to a robust algorithm. Meanwhile the snake is attracted towards image main features, ASM acts as a correction factor. The algorithm was tested independently on 180 frames and satisfying results were obtained: in 95% the maximum difference between automatic and experts segmentation was less than 12 pixels. |
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Centre de Visió per Computador – Dept. Informàtica, UAB Edifici O – Campus UAB, 08193 Bellater |
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0276-6547 |
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0-7803-8170-X |
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IAM @ iam @ GRC2003 |
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1512 |
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M. Gomez; J. Mauri; Eduard Fernandez-Nofrerias; Oriol Rodriguez-Leor; Carme Julia; Debora Gil; Petia Radeva |
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Reconstrucción de un modelo espacio-temporal de la luz del vaso a partir de secuencias de ecografía intracoronaria |
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2002 |
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XXXVIII Congreso Nacional de la Sociedad Española de Cardiología. |
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IAM;ADAS;MILAB |
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IAM @ iam @ GMF2002d |
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1516 |
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Author |
Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux |
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Title |
Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function |
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Conference Article |
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2008 |
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8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) |
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Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance. |
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Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model. |
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Venezia (Italia) |
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B-31470-08 |
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IAM @ iam @ GGV2008c |
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1521 |
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Author |
Debora Gil; Oriol Rodriguez; J. Mauri; Petia Radeva |
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Title |
Statistical descriptors of the Myocardial perfusion in angiographic images |
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Conference Article |
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2006 |
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Proc. Computers in Cardiology |
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677-680 |
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Anisotropic processing; intravascular ultrasound (IVUS); vessel border segmentation; vessel structure classification. |
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Restoration of coronary flow after primary percutaneous coronary intervention in acute myocardial infarction does not always correlate with adequate myocardial perfusion. Recently, coronary angiography has been used to assess microcirculation integrity (Myocardial BlushAnalysis, MBA). Although MBA correlates with patient prognosis there are few image processing methods addressing objective perfusion quantification. The goal of this work is to develop statistical descriptors of the myocardial dyeing pattern allowing objective assessment of myocardial perfusion. Experiments on healthy right coronary arteries show that our approach allows reliable measurements without any specific image acquisition protocol. |
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IAM;MILAB |
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IAM @ iam @ GRR2006 |
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1528 |
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Debora Gil; Petia Radeva; J. Mauri |
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Title |
Ivus Segmentation Via a Regularized Curvature Flow |
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2002 |
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X Congreso Anual de la Sociedad Española de Ingeniería Biomédica CASEIB 2002 |
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133-136 |
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Cardiac diseases are diagnosed and treated through a study of the morphology and dynamics of cardiac arteries. In- travascular Ultrasound (IVUS) imaging is of high interest to physicians since it provides both information. At the current state-of-the-art in image segmentation, a robust detection of the arterial lumen in IVUS demands manual intervention or ECG-gating. Manual intervention is a tedious and time consuming task that requires experienced observers, meanwhile ECG-gating is an acquisition technique not available in all clinical centers. We introduce a parametric algorithm that detects the arterial luminal border in in vivo sequences. The method consist in smoothing the sequences’ level surfaces under a regularized mean curvature flow that admits non-trivial steady states. The flow is based on a measure of the surface local smoothness that takes into account regularity of the surface curvature. |
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Saragossa, Espanya |
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IAM @ iam @ GRM2002 |
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1536 |
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Author |
Debora Gil; Petia Radeva; Jordi Saludes; J. Mauri |
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Title |
Automatic Segmentation of Artery Wall in Coronary IVUS Images: A Probabilistic Approach |
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2000 |
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International Conference on Pattern Recognition |
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4 |
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352-355 |
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Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results. |
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IAM @ iam @ GRS2000a |
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1537 |
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Aura Hernandez-Sabate; Debora Gil; Petia Radeva |
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On the usefulness of supervised learning for vessel border detection in IntraVascular Imaging |
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2005 |
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Proceeding of the 2005 conference on Artificial Intelligence Research and Development |
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67-74 |
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classification; vessel border modelling; IVUS |
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IntraVascular UltraSound (IVUS) imaging is a useful tool in diagnosis of cardiac diseases since sequences completely show the morphology of coronary vessels. Vessel borders detection, especially the external adventitia layer, plays a central role in morphological measures and, thus, their segmentation feeds development of medical imaging techniques. Deterministic approaches fail to yield optimal results due to the large amount of IVUS artifacts and vessel borders descriptors. We propose using classification techniques to learn the set of descriptors and parameters that best detect vessel borders. Statistical hypothesis test on the error between automated detections and manually traced borders by 4 experts show that our detections keep within inter-observer variability. |
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IOS Press |
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Amsterdam, The Netherlands |
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IAM @ iam @ HGR2005c |
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1549 |
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