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Author Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso edit  url
openurl 
  Title Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation Type Journal Article
  Year 2017 Publication Journal of Thoracic Oncology Abbreviated Journal JTO  
  Volume 12 Issue 1S Pages S596-S597  
  Keywords Thorax CT; diagnosis; Peripheral Pulmonary Nodule  
  Abstract A main weakness of virtual bronchoscopic navigation (VBN) is unsuccessful segmentation of distal branches approaching peripheral pulmonary nodules (PPN). CT scan acquisition protocol is pivotal for segmentation covering the utmost periphery. We hypothesize that application of continuous positive airway pressure (CPAP) during CT acquisition could improve visualization and segmentation of peripheral bronchi. The purpose of the present pilot study is to compare quality of segmentations under 4 CT acquisition modes: inspiration (INSP), expiration (EXP) and both with CPAP (INSP-CPAP and EXP-CPAP).  
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  Notes (up) IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ DGC2017a Serial 2883  
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Author H. Martin ; Jens Fagertun; Sergio Vera; Debora Gil edit   pdf
openurl 
  Title Medial structure generation for registration of anatomical structures Type Book Chapter
  Year 2017 Publication Skeletonization, Theory, Methods and Applications Abbreviated Journal  
  Volume 11 Issue Pages  
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  Notes (up) IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ MFV2017a Serial 2935  
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Author Carles Sanchez; Antonio Esteban Lansaque; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil edit   pdf
openurl 
  Title Towards a Videobronchoscopy Localization System from Airway Centre Tracking Type Conference Article
  Year 2017 Publication 12th International Conference on Computer Vision Theory and Applications Abbreviated Journal  
  Volume Issue Pages 352-359  
  Keywords Video-bronchoscopy; Lung cancer diagnosis; Airway lumen detection; Region tracking; Guided bronchoscopy navigation  
  Abstract Bronchoscopists use fluoroscopy to guide flexible bronchoscopy to the lesion to be biopsied without any kind of incision. Being fluoroscopy an imaging technique based on X-rays, the risk of developmental problems and cancer is increased in those subjects exposed to its application, so minimizing radiation is crucial. Alternative guiding systems such as electromagnetic navigation require specific equipment, increase the cost of the clinical procedure and still require fluoroscopy. In this paper we propose an image based guiding system based on the extraction of airway centres from intra-operative videos. Such anatomical landmarks are matched to the airway centreline extracted from a pre-planned CT to indicate the best path to the nodule. We present a
feasibility study of our navigation system using simulated bronchoscopic videos and a multi-expert validation of landmarks extraction in 3 intra-operative ultrathin explorations.
 
  Address Porto; Portugal; February 2017  
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  Area Expedition Conference VISAPP  
  Notes (up) IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ SEB2017 Serial 2943  
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Author Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso; Vanesa Vicens; Noelia Cubero de Frutos; Rosa Lopez Lisbona; Carles Sanchez; Agnes Borras; Antoni Rosell edit  doi
openurl 
  Title Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation Type Journal Article
  Year 2017 Publication European Respiratory Journal Abbreviated Journal ERJ  
  Volume 48 Issue 60 Pages PA776  
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  Notes (up) IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ DGC2017b Serial 2944  
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Author Debora Gil; Oriol Ramos Terrades; Elisa Minchole; Carles Sanchez; Noelia Cubero de Frutos; Marta Diez-Ferrer; Rosa Maria Ortiz; Antoni Rosell edit  url
openurl 
  Title Classification of Confocal Endomicroscopy Patterns for Diagnosis of Lung Cancer Type Conference Article
  Year 2017 Publication 6th Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging Abbreviated Journal  
  Volume 10550 Issue Pages 151-159  
  Keywords  
  Abstract Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy.

The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%.

We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results.
 
  Address Quebec; Canada; September 2017  
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  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CLIP  
  Notes (up) IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ GRM2017 Serial 2957  
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Author Rosa Maria Ortiz; Debora Gil; Elisa Minchole; Marta Diez-Ferrer; Noelia Cubero de Frutos edit  openurl
  Title Classification of Confolcal Endomicroscopy Patterns for Diagnosis of Lung Cancer Type Conference Article
  Year 2017 Publication 18th World Conference on Lung Cancer Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy.

The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%.

We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results.
 
  Address Yokohama; Japan; October 2017  
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  Area Expedition Conference IASLC WCLC  
  Notes (up) IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number Admin @ si @ OGM2017 Serial 3044  
Permanent link to this record
 

 
Author Esmitt Ramirez; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil edit   pdf
url  openurl
  Title Image-Based Bronchial Anatomy Codification for Biopsy Guiding in Video Bronchoscopy Type Conference Article
  Year 2018 Publication OR 2.0 Context-Aware Operating Theaters, Computer Assisted Robotic Endoscopy, Clinical Image-Based Procedures, and Skin Image Analysis Abbreviated Journal  
  Volume 11041 Issue Pages  
  Keywords Biopsy guiding; Bronchoscopy; Lung biopsy; Intervention guiding; Airway codification  
  Abstract Bronchoscopy examinations allow biopsy of pulmonary nodules with minimum risk for the patient. Even for experienced bronchoscopists, it is difficult to guide the bronchoscope to most distal lesions and obtain an accurate diagnosis. This paper presents an image-based codification of the bronchial anatomy for bronchoscopy biopsy guiding. The 3D anatomy of each patient is codified as a binary tree with nodes representing bronchial levels and edges labeled using their position on images projecting the 3D anatomy from a set of branching points. The paths from the root to leaves provide a codification of navigation routes with spatially consistent labels according to the anatomy observes in video bronchoscopy explorations. We evaluate our labeling approach as a guiding system in terms of the number of bronchial levels correctly codified, also in the number of labels-based instructions correctly supplied, using generalized mixed models and computer-generated data. Results obtained for three independent observers prove the consistency and reproducibility of our guiding system. We trust that our codification based on viewer’s projection might be used as a foundation for the navigation process in Virtual Bronchoscopy systems.  
  Address Granada; September 2018  
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  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference MICCAIW  
  Notes (up) IAM; 600.096; 600.075; 601.323; 600.145 Approved no  
  Call Number Admin @ si @ RSB2018b Serial 3137  
Permanent link to this record
 

 
Author Esmitt Ramirez; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell; Debora Gil edit   pdf
url  openurl
  Title BronchoX: bronchoscopy exploration software for biopsy intervention planning Type Journal Article
  Year 2018 Publication Healthcare Technology Letters Abbreviated Journal HTL  
  Volume 5 Issue 5 Pages 177–182  
  Keywords  
  Abstract Virtual bronchoscopy (VB) is a non-invasive exploration tool for intervention planning and navigation of possible pulmonary lesions (PLs). A VB software involves the location of a PL and the calculation of a route, starting from the trachea, to reach it. The selection of a VB software might be a complex process, and there is no consensus in the community of medical software developers in which is the best-suited system to use or framework to choose. The authors present Bronchoscopy Exploration (BronchoX), a VB software to plan biopsy interventions that generate physician-readable instructions to reach the PLs. The authors’ solution is open source, multiplatform, and extensible for future functionalities, designed by their multidisciplinary research and development group. BronchoX is a compound of different algorithms for segmentation, visualisation, and navigation of the respiratory tract. Performed results are a focus on the test the effectiveness of their proposal as an exploration software, also to measure its accuracy as a guiding system to reach PLs. Then, 40 different virtual planning paths were created to guide physicians until distal bronchioles. These results provide a functional software for BronchoX and demonstrate how following simple instructions is possible to reach distal lesions from the trachea.  
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  Notes (up) IAM; 600.096; 600.075; 601.323; 601.337; 600.145 Approved no  
  Call Number Admin @ si @ RSB2018a Serial 3132  
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Author Mireia Sole; J. Blanco; Debora Gil; Oliver Valero; Gothami Fonseka; M. Lawrie; Francesca Vidal; Zaida Sarrate edit   pdf
openurl 
  Title Chromosome Territories in Mice Spermatogenesis: A new three-dimensional methodology of study Type Conference Article
  Year 2017 Publication 11th European CytoGenesis Conference Abbreviated Journal  
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  Address Florencia; Italia; July 2017  
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  ISSN ISBN Medium  
  Area Expedition Conference ECA  
  Notes (up) IAM; 600.096; 600.145 Approved no  
  Call Number Admin @ si @ SBG2017a Serial 2936  
Permanent link to this record
 

 
Author Mireia Sole; Joan Blanco; Debora Gil; Gothami Fonseka; Richard Frodsham; Oliver Valero; Francesca Vidal; Zaida Sarrate edit   pdf
openurl 
  Title Is there a pattern of Chromosome territoriality along mice spermatogenesis? Type Conference Article
  Year 2017 Publication 3rd Spanish MeioNet Meeting Abstract Book Abbreviated Journal  
  Volume Issue Pages 55-56  
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  Address Miraflores de la Sierra; Madrid; June 2017  
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  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference MEIONET  
  Notes (up) IAM; 600.096; 600.145 Approved no  
  Call Number Admin @ si @ Serial 2958  
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