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Author |
Debora Gil; Petia Radeva; Jordi Saludes; J. Mauri |
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Title |
Automatic Segmentation of Artery Wall in Coronary IVUS Images: a Probabilistic Approach |
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Conference Article |
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2000 |
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Proceedings of CIC’2000 |
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Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results. |
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Cambridge, Massachussets |
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CIC |
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IAM;MILAB |
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IAM @ iam @ GRS2000 |
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1538 |
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Author |
Debora Gil; Petia Radeva; Fernando Vilariño |
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Title |
Anisotropic Contour Completion |
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Conference Article |
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2003 |
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Proceedings of the IEEE International Conference on Image Processing |
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I-869 |
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In this paper we introduce a novel application of the diffusion tensor for anisotropic image processing. The Anisotropic Contour Completion (ACC) we suggest consists in extending the characteristic function of the open curve by means of a degenerated diffusion tensor that prevents any diffusion in the normal direction. We show that ACC is equivalent to a dilation with a continuous elliptic structural element that takes into account the local orientation of the contours to be closed. Experiments on contours extracted from real images show that ACC produces shapes able to adapt to any curve in an active contour framework. 1. |
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Barcelona, Spain |
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Barcelona, Spain |
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0-7803-7751-6 |
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ICIP |
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IAM;MV;MILAB;SIAI |
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IAM @ iam @ GRV2003 |
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1539 |
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Author |
Debora Gil; Oriol Rodriguez-Leor; Petia Radeva; Aura Hernandez-Sabate |
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Title |
Assessing Artery Motion Compensation in IVUS |
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Book Chapter |
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Year |
2007 |
Publication |
Computer Analysis Of Images And Patterns |
Abbreviated Journal |
LNCS |
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4673 |
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213-220 |
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Keywords |
validation standards; quality measures; IVUS motion compensation; conservation laws; Fourier development |
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Cardiac dynamics suppression is a main issue for visual improvement and computation of tissue mechanical properties in IntraVascular UltraSound (IVUS). Although in recent times several motion compensation techniques have arisen, there is a lack of objective evaluation of motion reduction in in vivo pullbacks. We consider that the assessment protocol deserves special attention for the sake of a clinical applicability as reliable as possible. Our work focuses on defining a quality measure and a validation protocol assessing IVUS motion compensation. On the grounds of continuum mechanics laws we introduce a novel score measuring motion reduction in in vivo sequences. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases. |
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Springerlink |
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Heidelberg |
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Lecture Notes in Computer Science |
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978-3-540-74271-5 |
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IAM;MILAB |
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IAM @ iam @ GRR2007 |
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1540 |
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Author |
F.Guirado; Ana Ripoll; C.Roig; Aura Hernandez-Sabate; Emilio Luque |
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Title |
Exploiting Throughput for Pipeline Execution in Streaming Image Processing Applications |
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Book Chapter |
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2006 |
Publication |
Euro-Par 2006 Parallel Processing |
Abbreviated Journal |
LNCS |
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4128 |
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1095-1105 |
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12th International Euro–Par Conference |
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There is a large range of image processing applications that act on an input sequence of image frames that are continuously received. Throughput is a key performance measure to be optimized when execu- ting them. In this paper we propose a new task replication methodology for optimizing throughput for an image processing application in the field of medicine. The results show that by applying the proposed methodo- logy we are able to achieve the desired throughput in all cases, in such a way that the input frames can be processed at any given rate. |
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Springer-Verlag Berlin Heidelberg |
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Dresden, Germany (European Union) |
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UAB; W, E.N.; et al. |
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Lecture Notes In Computer Science |
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Euro–Par |
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IAM |
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IAM @ iam @ GRR2006a |
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1542 |
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Author |
Aura Hernandez-Sabate |
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Title |
Exploring Arterial Dynamics and Structures in IntraVascular Ultrasound Sequences |
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Book Whole |
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2009 |
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PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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Cardiovascular diseases are a leading cause of death in developed countries. Most of them are caused by arterial (specially coronary) diseases, mainly caused by plaque accumulation. Such pathology narrows blood flow (stenosis) and affects artery bio- mechanical elastic properties (atherosclerosis). In the last decades, IntraVascular UltraSound (IVUS) has become a usual imaging technique for the diagnosis and follow up of arterial diseases. IVUS is a catheter-based imaging technique which shows a sequence of cross sections of the artery under study. Inspection of a single image gives information about the percentage of stenosis. Meanwhile, inspection of longitudinal views provides information about artery bio-mechanical properties, which can prevent a fatal outcome of the cardiovascular disease. On one hand, dynamics of arteries (due to heart pumping among others) is a major artifact for exploring tissue bio-mechanical properties. On the other one, manual stenosis measurements require a manual tracing of vessel borders, which is a time-consuming task and might suffer from inter-observer variations. This PhD thesis proposes several image processing tools for exploring vessel dy- namics and structures. We present a physics-based model to extract, analyze and correct vessel in-plane rigid dynamics and to retrieve cardiac phase. Furthermore, we introduce a deterministic-statistical method for automatic vessel borders detection. In particular, we address adventitia layer segmentation. An accurate validation pro- tocol to ensure reliable clinical applicability of the methods is a crucial step in any proposal of an algorithm. In this thesis we take special care in designing a valida- tion protocol for each approach proposed and we contribute to the in vivo dynamics validation with a quantitative and objective score to measure the amount of motion suppressed. |
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Ph.D. thesis |
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Publisher |
Ediciones Graficas Rey |
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Debora Gil |
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978-84-937261-6-4 |
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IAM; |
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IAM @ iam @ Her2009 |
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1543 |
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Author |
Aura Hernandez-Sabate; Debora Gil; Petia Radeva |
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Title |
On the usefulness of supervised learning for vessel border detection in IntraVascular Imaging |
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Conference Article |
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2005 |
Publication |
Proceeding of the 2005 conference on Artificial Intelligence Research and Development |
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67-74 |
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classification; vessel border modelling; IVUS |
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IntraVascular UltraSound (IVUS) imaging is a useful tool in diagnosis of cardiac diseases since sequences completely show the morphology of coronary vessels. Vessel borders detection, especially the external adventitia layer, plays a central role in morphological measures and, thus, their segmentation feeds development of medical imaging techniques. Deterministic approaches fail to yield optimal results due to the large amount of IVUS artifacts and vessel borders descriptors. We propose using classification techniques to learn the set of descriptors and parameters that best detect vessel borders. Statistical hypothesis test on the error between automated detections and manually traced borders by 4 experts show that our detections keep within inter-observer variability. |
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IOS Press |
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Amsterdam, The Netherlands |
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IAM;MILAB |
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IAM @ iam @ HGR2005c |
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1549 |
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Author |
Aura Hernandez-Sabate; Debora Gil; Albert Teis |
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Title |
How Do Conservation Laws Define a Motion Suppression Score in In-Vivo Ivus Sequences? |
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Conference Article |
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2007 |
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Proc. IEEE Ultrasonics Symp |
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2231-2234 |
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validation standards; IVUS motion compensation; conservation laws. |
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Evaluation of arterial tissue biomechanics for diagnosis and treatment of cardiovascular diseases is an active research field in the biomedical imaging processing area. IntraVascular UltraSound (IVUS) is a unique tool for such assessment since it reflects tissue morphology and deformation. A proper quantification and visualization of both properties is hindered by vessel structures misalignments introduced by cardiac dynamics. This has encouraged development of IVUS motion compensation techniques. However, there is a lack of an objective evaluation of motion reduction ensuring a reliable clinical application This work reports a novel score, the Conservation of Density Rate (CDR), for validation of motion compensation in in-vivo pullbacks. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases. |
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IAM |
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IAM @ iam @ HTG2007 |
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1550 |
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Author |
Aura Hernandez-Sabate; Monica Mitiko; Sergio Shiguemi; Debora Gil |
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Title |
A validation protocol for assessing cardiac phase retrieval in IntraVascular UltraSound |
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Conference Article |
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2010 |
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Computing in Cardiology |
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37 |
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899-902 |
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A good reliable approach to cardiac triggering is of utmost importance in obtaining accurate quantitative results of atherosclerotic plaque burden from the analysis of IntraVascular UltraSound. Although, in the last years, there has been an increase in research of methods for retrospective gating, there is no general consensus in a validation protocol. Many methods are based on quality assessment of longitudinal cuts appearance and those reporting quantitative numbers do not follow a standard protocol. Such heterogeneity in validation protocols makes faithful comparison across methods a difficult task. We propose a validation protocol based on the variability of the retrieved cardiac phase and explore the capability of several quality measures for quantifying such variability. An ideal detector, suitable for its application in clinical practice, should produce stable phases. That is, it should always sample the same cardiac cycle fraction. In this context, one should measure the variability (variance) of a candidate sampling with respect a ground truth (reference) sampling, since the variance would indicate how spread we are aiming a target. In order to quantify the deviation between the sampling and the ground truth, we have considered two quality scores reported in the literature: signed distance to the closest reference sample and distance to the right of each reference sample. We have also considered the residuals of the regression line of reference against candidate sampling. The performance of the measures has been explored on a set of synthetic samplings covering different cardiac cycle fractions and variabilities. From our simulations, we conclude that the metrics related to distances are sensitive to the shift considered while the residuals are robust against fraction and variabilities as far as one can establish a pair-wise correspondence between candidate and reference. We will further investigate the impact of false positive and negative detections in experimental data. |
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IEEE |
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0276-6547 |
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978-1-4244-7318-2 |
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CINC |
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IAM; |
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IAM @ iam @ HSM2010 |
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1551 |
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Author |
Aura Hernandez-Sabate; Petia Radeva; Antonio Tovar; Debora Gil |
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Title |
Vessel structures alignment by spectral analysis of ivus sequences |
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Conference Article |
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2006 |
Publication |
Proc. of CVII, MICCAI Workshop |
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39-36 |
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Three-dimensional intravascular ultrasound (IVUS) allows to visualize and obtain volumetric measurements of coronary lesions through an exploration of the cross sections and longitudinal views of arteries. However, the visualization and subsequent morpho-geometric measurements in IVUS longitudinal cuts are subject to distortion caused by periodic image/vessel motion around the IVUS catheter. Usually, to overcome the image motion artifact ECG-gating and image-gated approaches are proposed, leading to slowing the pullback acquisition or disregarding part of IVUS data. In this paper, we argue that the image motion is due to 3-D vessel geometry as well as cardiac dynamics, and propose a dynamic model based on the tracking of an elliptical vessel approximation to recover the rigid transformation and align IVUS images without loosing any IVUS data. We report an extensive validation with synthetic simulated data and in vivo IVUS sequences of 30 patients achieving an average reduction of the image artifact of 97% in synthetic data and 79% in real-data. Our study shows that IVUS alignment improves longitudinal analysis of the IVUS data and is a necessary step towards accurate reconstruction and volumetric measurements of 3-D IVUS. |
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Copenhaguen (Denmark), |
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1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) |
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IAM; MILAB |
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IAM @ iam @ HRT2006 |
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1552 |
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Author |
Aura Hernandez-Sabate; David Rotger; Debora Gil |
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Title |
Image-based ECG sampling of IVUS sequences |
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2008 |
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Proc. IEEE Ultrasonics Symp. IUS 2008 |
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1330-1333 |
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Longitudinal Motion; Image-based ECG-gating; Fourier analysis |
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Longitudinal motion artifacts in IntraVascular UltraSound (IVUS) sequences hinders a properly 3D reconstruction and vessel measurements. Most of current techniques base on the ECG signal to obtain a gated pullback without the longitudinal artifact by using a specific hardware or the ECG signal itself. The potential of IVUS images processing for phase retrieval still remains little explored. In this paper, we present a fast forward image-based algorithm to approach ECG sampling. Inspired on the fact that maximum and minimum lumen areas are related to end-systole and end-diastole, our cardiac phase retrieval is based on the analysis of tissue density of mass along the sequence. The comparison between automatic and manual phase retrieval (0.07 ± 0.07 mm. of error) encourages a deep validation contrasting with ECG signals. |
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Beijing (China) |
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IAM;MILAB |
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IAM @ iam @ HRG2008 |
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1553 |
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