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Debora Gil; Oriol Ramos Terrades; Elisa Minchole; Carles Sanchez; Noelia Cubero de Frutos; Marta Diez-Ferrer; Rosa Maria Ortiz; Antoni Rosell |
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Title |
Classification of Confocal Endomicroscopy Patterns for Diagnosis of Lung Cancer |
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Conference Article |
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2017 |
Publication |
6th Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging |
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10550 |
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151-159 |
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Abstract |
Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy.
The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%.
We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results. |
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Quebec; Canada; September 2017 |
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IAM; 600.096; 600.075; 600.145;DAG |
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Admin @ si @ GRM2017 |
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2957 |
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Author |
Debora Gil; Antonio Esteban Lansaque; Sebastian Stefaniga; Mihail Gaianu; Carles Sanchez |
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Title |
Data Augmentation from Sketch |
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Conference Article |
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Year |
2019 |
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International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging |
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11840 |
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155-162 |
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Data augmentation; cycleGANs; Multi-objective optimization |
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State of the art machine learning methods need huge amounts of data with unambiguous annotations for their training. In the context of medical imaging this is, in general, a very difficult task due to limited access to clinical data, the time required for manual annotations and variability across experts. Simulated data could serve for data augmentation provided that its appearance was comparable to the actual appearance of intra-operative acquisitions. Generative Adversarial Networks (GANs) are a powerful tool for artistic style transfer, but lack a criteria for selecting epochs ensuring also preservation of intra-operative content.
We propose a multi-objective optimization strategy for a selection of cycleGAN epochs ensuring a mapping between virtual images and the intra-operative domain preserving anatomical content. Our approach has been applied to simulate intra-operative bronchoscopic videos and chest CT scans from virtual sketches generated using simple graphical primitives. |
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Shenzhen; China; October 2019 |
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IAM; 600.145; 601.337; 600.139; 600.145 |
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Admin @ si @ GES2019 |
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3359 |
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Debora Gil; Jaume Garcia; Ruth Aris; Guillaume Houzeaux; Manuel Vazquez |
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Title |
A Riemmanian approach to cardiac fiber architecture modelling |
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2009 |
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1st International Conference on Mathematical & Computational Biomedical Engineering |
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59-62 |
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cardiac fiber architecture; diffusion tensor magnetic resonance imaging; differential (Rie- mannian) geometry. |
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There is general consensus that myocardial fiber architecture should be modelled in order to fully understand the electromechanical properties of the Left Ventricle (LV). Diffusion Tensor magnetic resonance Imaging (DTI) is the reference image modality for rapid measurement of fiber orientations by means of the tensor principal eigenvectors. In this work, we present a mathematical framework for across subject comparison of the local geometry of the LV anatomy including the fiber architecture from the statistical analysis of DTI studies. We use concepts of differential geometry for defining a parametric domain suitable for statistical analysis of a low number of samples. We use Riemannian metrics to define a consistent computation of DTI principal eigenvector modes of variation. Our framework has been applied to build an atlas of the LV fiber architecture from 7 DTI normal canine hearts. |
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Swansea (UK) |
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Nithiarasu, R.L.R.V.L. |
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CMBE |
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IAM |
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IAM @ iam @ FGA2009 |
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1520 |
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Author |
Patricia Marquez; Debora Gil; Aura Hernandez-Sabate |
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Title |
Evaluation of the Capabilities of Confidence Measures for Assessing Optical Flow Quality |
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Conference Article |
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2013 |
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ICCV Workshop on Computer Vision in Vehicle Technology: From Earth to Mars |
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624-631 |
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Assessing Optical Flow (OF) quality is essential for its further use in reliable decision support systems. The absence of ground truth in such situations leads to the computation of OF Confidence Measures (CM) obtained from either input or output data. A fair comparison across the capabilities of the different CM for bounding OF error is required in order to choose the best OF-CM pair for discarding points where OF computation is not reliable. This paper presents a statistical probabilistic framework for assessing the quality of a given CM. Our quality measure is given in terms of the percentage of pixels whose OF error bound can not be determined by CM values. We also provide statistical tools for the computation of CM values that ensures a given accuracy of the flow field. |
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Sydney; Australia; December 2013 |
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CVTT:E2M |
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IAM; ADAS; 600.044; 600.057; 601.145 |
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Admin @ si @ MGH2013b |
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2351 |
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Author |
Guillermo Torres; Jan Rodríguez Dueñas; Sonia Baeza; Antoni Rosell; Carles Sanchez; Debora Gil |
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Title |
Prediction of Malignancy in Lung Cancer using several strategies for the fusion of Multi-Channel Pyradiomics Images |
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Conference Article |
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Year |
2023 |
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7th Workshop on Digital Image Processing for Medical and Automotive Industry in the framework of SYNASC 2023 |
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This study shows the generation process and the subsequent study of the representation space obtained by extracting GLCM texture features from computer-aided tomography (CT) scans of pulmonary nodules (PN). For this, data from 92 patients from the Germans Trias i Pujol University Hospital were used. The workflow focuses on feature extraction using Pyradiomics and the VGG16 Convolutional Neural Network (CNN). The aim of the study is to assess whether the data obtained have a positive impact on the diagnosis of lung cancer (LC). To design a machine learning (ML) model training method that allows generalization, we train SVM and neural network (NN) models, evaluating diagnosis performance using metrics defined at slice and nodule level. |
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DIPMAI |
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IAM |
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Admin @ si @ TRB2023 |
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3926 |
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Mireia Sole; Joan Blanco; Debora Gil; Oliver Valero; G. Fonseka; M. Lawrie; Francesca Vidal; Zaida Sarrate |
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Title |
Chromosome Territories in Mice Spermatogenesis: A new three-dimensional methodology of study |
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Conference Article |
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2017 |
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11th European CytoGenesis Conference |
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Florencia; Italia; July 2017 |
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ECA |
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IAM; 600.096; 600.145 |
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Admin @ si @ SBG2017a |
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2936 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Using statistical inference for designing termination conditions ensuring convergence of Evolutionary Algorithms |
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Conference Article |
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2011 |
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11th European Conference on Artificial Life |
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A main challenge in Evolutionary Algorithms (EAs) is determining a termination condition ensuring stabilization close to the optimum in real-world applications. Although for known test functions distribution-based quantities are good candidates (as far as suitable parameters are used), in real-world problems an open question still remains unsolved. How can we estimate an upper-bound for the termination condition value ensuring a given accuracy for the (unknown) EA solution?
We claim that the termination problem would be fully solved if we defined a quantity (depending only on the EA output) behaving like the solution accuracy. The open question would be, then, satisfactorily answered if we had a model relating both quantities, since accuracy could be predicted from the alternative quantity. We present a statistical inference framework addressing two topics: checking the correlation between the two quantities and defining a regression model for predicting (at a given confidence level) accuracy values from the EA output. |
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Paris, France |
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ECAL |
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IAM; |
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IAM @ iam @ RGG2011b |
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1678 |
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Carles Sanchez; Debora Gil; R. Tazi; Jorge Bernal; Y. Ruiz; L. Planas; F. Javier Sanchez; Antoni Rosell |
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Quasi-real time digital assessment of Central Airway Obstruction |
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Conference Article |
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2015 |
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3rd European congress for bronchology and interventional pulmonology ECBIP2015 |
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Barcelona; Spain; April 2015 |
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IAM; MV; 600.075 |
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SGT2015 |
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2612 |
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Author |
Patricia Marquez;Debora Gil;Aura Hernandez-Sabate |
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Title |
A Complete Confidence Framework for Optical Flow |
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Conference Article |
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2012 |
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12th European Conference on Computer Vision – Workshops and Demonstrations |
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7584 |
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2 |
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124-133 |
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Optical flow, confidence measures, sparsification plots, error prediction plots |
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Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations. |
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Springer-Verlag |
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Florence, Italy, October 7-13, 2012 |
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Andrea Fusiello, Vittorio Murino ,Rita Cucchiara |
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978-3-642-33867-0 |
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ECCVW |
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IAM;ADAS; |
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IAM @ iam @ MGH2012b |
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1991 |
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Saad Minhas; Aura Hernandez-Sabate; Shoaib Ehsan; Katerine Diaz; Ales Leonardis; Antonio Lopez; Klaus McDonald Maier |
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LEE: A photorealistic Virtual Environment for Assessing Driver-Vehicle Interactions in Self-Driving Mode |
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Conference Article |
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2016 |
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14th European Conference on Computer Vision Workshops |
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9915 |
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894-900 |
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Simulation environment; Automated Driving; Driver-Vehicle interaction |
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Photorealistic virtual environments are crucial for developing and testing automated driving systems in a safe way during trials. As commercially available simulators are expensive and bulky, this paper presents a low-cost, extendable, and easy-to-use (LEE) virtual environment with the aim to highlight its utility for level 3 driving automation. In particular, an experiment is performed using the presented simulator to explore the influence of different variables regarding control transfer of the car after the system was driving autonomously in a highway scenario. The results show that the speed of the car at the time when the system needs to transfer the control to the human driver is critical. |
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Amsterdam; The Netherlands; October 2016 |
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ECCVW |
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ADAS;IAM; 600.085; 600.076 |
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MHE2016 |
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2865 |
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