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Sonia Baeza; R.Domingo; M.Salcedo; G.Moragas; J.Deportos; I.Garcia Olive; Carles Sanchez; Debora Gil; Antoni Rosell |
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Artificial Intelligence to Optimize Pulmonary Embolism Diagnosis During Covid-19 Pandemic by Perfusion SPECT/CT, a Pilot Study |
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2021 |
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American Journal of Respiratory and Critical Care Medicine |
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IAM; 600.145 |
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Admin @ si @ BDS2021 |
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3591 |
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Sonia Baeza; Debora Gil; Ignasi Garcia Olive; Maite Salcedo Pujantell; Jordi Deportos; Carles Sanchez; Guillermo Torres; Gloria Moragas; Antoni Rosell |
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Correction: A novel intelligent radiomic analysis of perfusion SPECT/CT images to optimize pulmonary embolism diagnosis in COVID-19 patients |
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2023 |
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European Journal of Nuclear Medicine and Molecular Imaging |
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EJNMMI PHYSICS |
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10 |
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1 |
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13 |
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Keywords |
early diagnosis; Lung Cancer; nodule diagnosis; nodule diagnosis; Radiomics; Screening |
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This study shows the generation process and the subsequent study of the representation space obtained by extracting GLCM texture features from computer-aided tomography (CT) scans of pulmonary nodules (PN). For this, data from 92 patients from the Germans Trias i Pujol University Hospital were used. The workflow focuses on feature extraction using Pyradiomics and the VGG16 Convolutional Neural Network (CNN). The aim of the study is to assess whether the data obtained have a positive impact on the diagnosis of lung cancer (LC). To design a machine learning (ML) model training method that allows generalization, we train SVM and neural network (NN) models, evaluating diagnosis performance using metrics defined at slice and nodule level. |
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BGG2023 |
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3858 |
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Sonia Baeza; Debora Gil; I.Garcia Olive; M.Salcedo; J.Deportos; Carles Sanchez; Guillermo Torres; G.Moragas; Antoni Rosell |
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Title |
A novel intelligent radiomic analysis of perfusion SPECT/CT images to optimize pulmonary embolism diagnosis in COVID-19 patients |
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Journal Article |
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Year |
2022 |
Publication |
EJNMMI Physics |
Abbreviated Journal |
EJNMMI-PHYS |
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9 |
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1, Article 84 |
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1-17 |
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Background: COVID-19 infection, especially in cases with pneumonia, is associated with a high rate of pulmonary embolism (PE). In patients with contraindications for CT pulmonary angiography (CTPA) or non-diagnostic CTPA, perfusion single-photon emission computed tomography/computed tomography (Q-SPECT/CT) is a diagnostic alternative. The goal of this study is to develop a radiomic diagnostic system to detect PE based only on the analysis of Q-SPECT/CT scans.
Methods: This radiomic diagnostic system is based on a local analysis of Q-SPECT/CT volumes that includes both CT and Q-SPECT values for each volume point. We present a combined approach that uses radiomic features extracted from each scan as input into a fully connected classifcation neural network that optimizes a weighted crossentropy loss trained to discriminate between three diferent types of image patterns (pixel sample level): healthy lungs (control group), PE and pneumonia. Four types of models using diferent confguration of parameters were tested.
Results: The proposed radiomic diagnostic system was trained on 20 patients (4,927 sets of samples of three types of image patterns) and validated in a group of 39 patients (4,410 sets of samples of three types of image patterns). In the training group, COVID-19 infection corresponded to 45% of the cases and 51.28% in the test group. In the test group, the best model for determining diferent types of image patterns with PE presented a sensitivity, specifcity, positive predictive value and negative predictive value of 75.1%, 98.2%, 88.9% and 95.4%, respectively. The best model for detecting
pneumonia presented a sensitivity, specifcity, positive predictive value and negative predictive value of 94.1%, 93.6%, 85.2% and 97.6%, respectively. The area under the curve (AUC) was 0.92 for PE and 0.91 for pneumonia. When the results obtained at the pixel sample level are aggregated into regions of interest, the sensitivity of the PE increases to 85%, and all metrics improve for pneumonia.
Conclusion: This radiomic diagnostic system was able to identify the diferent lung imaging patterns and is a frst step toward a comprehensive intelligent radiomic system to optimize the diagnosis of PE by Q-SPECT/CT. |
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5 dec 2022 |
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Springer |
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IAM |
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Admin @ si @ BGG2022 |
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3759 |
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Author |
Sonia Baeza; Debora Gil; Carles Sanchez; Guillermo Torres; Ignasi Garcia Olive; Ignasi Guasch; Samuel Garcia Reina; Felipe Andreo; Jose Luis Mate; Jose Luis Vercher; Antonio Rosell |
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Title |
Biopsia virtual radiomica para el diagnóstico histológico de nódulos pulmonares – Resultados intermedios del proyecto Radiolung |
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Conference Article |
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2023 |
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SEPAR |
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Granada; Spain; June 2023 |
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Admin @ si @ BGS2023 |
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3951 |
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Author |
Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil |
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Title |
Volumetric Anatomical Parameterization and Meshing for Inter-patient Liver Coordinate System Deffinition |
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Conference Article |
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2013 |
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16th International Conference on Medical Image Computing and Computer Assisted Intervention |
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Nagoya; Japan; September 2013 |
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MICCAI |
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Admin @ si @ VGG2013 |
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2301 |
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Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil |
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Title |
Optimal Medial Surface Generation for Anatomical Volume Representations |
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Book Chapter |
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2012 |
Publication |
Abdominal Imaging. Computational and Clinical Applications |
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LNCS |
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7601 |
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265-273 |
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Medial surface representation; volume reconstruction |
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Medial representations are a widely used technique in abdominal organ shape representation and parametrization. Those methods require good medial manifolds as a starting point. Any medial
surface used to parametrize a volume should be simple enough to allow an easy manipulation and complete enough to allow an accurate reconstruction of the volume. Obtaining good quality medial
surfaces is still a problem with current iterative thinning methods. This forces the usage of generic, pre-calculated medial templates that are adapted to the final shape at the cost of a drop in volume reconstruction.
This paper describes an operator for generation of medial structures that generates clean and complete manifolds well suited for their further use in medial representations of abdominal organ volumes. While being simpler than thinning surfaces, experiments show its high performance in volume reconstruction and preservation of medial surface main branching topology. |
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Nice, France |
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Springer Berlin Heidelberg |
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Yoshida, Hiroyuki and Hawkes, David and Vannier, MichaelW. |
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Lecture Notes in Computer Science |
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0302-9743 |
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978-3-642-33611-9 |
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STACOM |
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IAM @ iam @ VGG2012b |
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1988 |
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Author |
Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil |
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Title |
A medial map capturing the essential geometry of organs |
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2012 |
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ISBI Workshop on Open Source Medical Image Analysis software |
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1691 - 1694 |
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Medial Surface Representation, Volume Reconstruction,Geometry , Image reconstruction , Liver , Manifolds , Shape , Surface morphology , Surface reconstruction |
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Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Accurate computation of one pixel wide medial surfaces is mandatory. Those surfaces must represent faithfully the geometry of the volume. Although morphological methods produce excellent results in 2D, their complexity and quality drops across dimensions, due to a more complex description of pixel neighborhoods. This paper introduces a continuous operator for accurate and efficient computation of medial structures of arbitrary dimension. Our experiments show its higher performance for medical imaging applications in terms of simplicity of medial structures and capability for reconstructing the anatomical volume |
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Barcelona,Spain |
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IEEE |
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1945-7928 |
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978-1-4577-1857-1 |
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ISBI |
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IAM |
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IAM @ iam @ VGG2012a |
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1989 |
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Author |
Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil |
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Title |
A Novel Cochlear Reference Frame Based On The Laplace Equation |
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Conference Article |
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2015 |
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29th international Congress and Exhibition on Computer Assisted Radiology and Surgery |
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10 |
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1 |
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1-312 |
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Poster |
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Barcelona; Spain; June 2015 |
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CARS |
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IAM; 600.075 |
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Admin @ si @ VGG2015 |
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2615 |
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Author |
Sergio Vera; Debora Gil; Miguel Angel Gonzalez Ballester |
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Title |
Anatomical parameterization for volumetric meshing of the liver |
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Conference Article |
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2014 |
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SPIE – Medical Imaging |
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9036 |
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Coordinate System; Anatomy Modeling; Parameterization |
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A coordinate system describing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to specific anatomical landmarks, the coordinate system allows integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric coordinate systems over the surface of anatomical shapes, given their flexibility to set values
at specific locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at sites
of limited geometric diversity. In this paper we present a method for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the
volume medial surface. We have applied the methodology to define a common reference system for the liver shape and functional anatomy. This reference system sets a solid base for creating anatomical models of the patient’s liver, and allows comparing livers from several patients in a common framework of reference. |
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Amsterdam; September 2014 |
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SPIE-MI |
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IAM; 600.075 |
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Admin @ si @ VGG2014 |
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2456 |
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Author |
Sergio Vera; Debora Gil; Antonio Lopez; Miguel Angel Gonzalez Ballester |
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Title |
Multilocal Creaseness Measure |
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2012 |
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The Insight Journal |
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IJ |
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Ridges, Valley, Creaseness, Structure Tensor, Skeleton, |
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This document describes the implementation using the Insight Toolkit of an algorithm for detecting creases (ridges and valleys) in N-dimensional images, based on the Local Structure Tensor of the image. In addition to the filter used to calculate the creaseness image, a filter for the computation of the structure tensor is also included in this submission. |
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Alma IT Systems |
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english |
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english |
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IAM;ADAS; |
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IAM @ iam @ VGL2012 |
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1840 |
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