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	Author	Aura Hernandez-Sabate; Debora Gil
	Title	The Benefits of IVUS Dynamics for Retrieving Stable Models of Arteries			Type	Book Chapter
	Year	2012	Publication	Intravascular Ultrasound	Abbreviated Journal
	Volume		Issue		Pages	185-206
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher	Intech	Place of Publication		Editor	Yasuhiro Honda
	Language	English	Summary Language	english	Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN	978-953-307-900-4	Medium
	Area		Expedition		Conference
	Notes	IAM; ADAS			Approved	no
	Call Number	IAM @ iam @ HeG2012			Serial	1684
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	Author	David Roche; Debora Gil; Jesus Giraldo
	Title	Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models?			Type	Book Chapter
	Year	2014	Publication	G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology	Abbreviated Journal
	Volume	796	Issue	3	Pages	159-181
	Keywords	β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model
	Abstract	Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.
	Address
	Corporate Author				Thesis
	Publisher	Springer Netherlands	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0065-2598	ISBN	978-94-007-7422-3	Medium
	Area		Expedition		Conference
	Notes	IAM; 600.075			Approved	no
	Call Number	IAM @ iam @ RGG2014			Serial	2197
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	Author	Debora Gil; Jordi Gonzalez; Gemma Sanchez (eds)
	Title	Computer Vision: Advances in Research and Development			Type	Book Whole
	Year	2007	Publication	Proceedings of the 2nd CVC International Workshop	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher	UAB	Place of Publication	Bellaterra (Spain)	Editor	Debora Gil; Jordi Gonzalez; Gemma Sanchez
	Language		Summary Language		Original Title
	Series Editor		Series Title	2	Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN	978-84-935251-4-9	Medium
	Area		Expedition		Conference
	Notes	IAM; ISE; DAG			Approved	no
	Call Number	IAM @ iam @ GGS2007			Serial	1493
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	Author	Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil
	Title	Optimal Medial Surface Generation for Anatomical Volume Representations			Type	Book Chapter
	Year	2012	Publication	Abdominal Imaging. Computational and Clinical Applications	Abbreviated Journal	LNCS
	Volume	7601	Issue		Pages	265-273
	Keywords	Medial surface representation; volume reconstruction
	Abstract	Medial representations are a widely used technique in abdominal organ shape representation and parametrization. Those methods require good medial manifolds as a starting point. Any medial surface used to parametrize a volume should be simple enough to allow an easy manipulation and complete enough to allow an accurate reconstruction of the volume. Obtaining good quality medial surfaces is still a problem with current iterative thinning methods. This forces the usage of generic, pre-calculated medial templates that are adapted to the final shape at the cost of a drop in volume reconstruction. This paper describes an operator for generation of medial structures that generates clean and complete manifolds well suited for their further use in medial representations of abdominal organ volumes. While being simpler than thinning surfaces, experiments show its high performance in volume reconstruction and preservation of medial surface main branching topology.
	Address	Nice, France
	Corporate Author				Thesis
	Publisher	Springer Berlin Heidelberg	Place of Publication		Editor	Yoshida, Hiroyuki and Hawkes, David and Vannier, MichaelW.
	Language		Summary Language		Original Title
	Series Editor		Series Title	Lecture Notes in Computer Science	Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-642-33611-9	Medium
	Area		Expedition		Conference	STACOM
	Notes	IAM			Approved	no
	Call Number	IAM @ iam @ VGG2012b			Serial	1988
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	Author	Carles Sanchez;F. Javier Sanchez; Antoni Rosell; Debora Gil
	Title	An illumination model of the trachea appearance in videobronchoscopy images			Type	Book Chapter
	Year	2012	Publication	Image Analysis and Recognition	Abbreviated Journal	LNCS
	Volume	7325	Issue		Pages	313-320
	Keywords	Bronchoscopy, tracheal ring, stenosis assesment, trachea appearance model, segmentation
	Abstract	Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways. This imaging modality provides realistic images and allows non-invasive minimal intervention procedures. Tracheal procedures are routinary interventions that require assessment of the percentage of obstructed pathway for injury (stenosis) detection. Visual assessment in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error. This paper introduces an automatic method for the estimation of steneosed trachea percentage reduction in videobronchoscopic images. We look for tracheal rings , whose deformation determines the degree of obstruction. For ring extraction , we present a ring detector based on an illumination and appearance model. This model allows us to parametrise the ring detection. Finally, we can infer optimal estimation parameters for any video resolution.
	Address	Aveiro, Portugal
	Corporate Author				Thesis
	Publisher	Springer Berlin Heidelberg	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title	Lecture Notes in Computer Science	Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-642-31297-7	Medium
	Area	800	Expedition		Conference	ICIAR
	Notes	MV;IAM			Approved	no
	Call Number	IAM @ iam @ SSR2012			Serial	1898
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	Author	Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru; Miguel Angel Gonzalez Ballester
	Title	Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs			Type	Book Chapter
	Year	2012	Publication	Workshop on Computational and Clinical Applications in Abdominal Imaging	Abbreviated Journal
	Volume	7029	Issue		Pages	223–230
	Keywords	medial manifolds, abdomen.
	Abstract	Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.
	Address	Toronto; Canada;
	Corporate Author				Thesis
	Publisher	Springer Link	Place of Publication	Berlin	Editor	H. Yoshida et al
	Language	English	Summary Language	English	Original Title
	Series Editor		Series Title	Lecture Notes in Computer Science	Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-642-28556-1	Medium
	Area		Expedition		Conference	ABDI
	Notes	IAM;MV			Approved	no
	Call Number	IAM @ iam @ VGB2012			Serial	1834
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	Author	Debora Gil; Oriol Rodriguez-Leon; Petia Radeva; Aura Hernandez-Sabate
	Title	Assessing Artery Motion Compensation in IVUS			Type	Book Chapter
	Year	2007	Publication	Computer Analysis Of Images And Patterns	Abbreviated Journal	LNCS
	Volume	4673	Issue		Pages	213-220
	Keywords	validation standards; quality measures; IVUS motion compensation; conservation laws; Fourier development
	Abstract	Cardiac dynamics suppression is a main issue for visual improvement and computation of tissue mechanical properties in IntraVascular UltraSound (IVUS). Although in recent times several motion compensation techniques have arisen, there is a lack of objective evaluation of motion reduction in in vivo pullbacks. We consider that the assessment protocol deserves special attention for the sake of a clinical applicability as reliable as possible. Our work focuses on defining a quality measure and a validation protocol assessing IVUS motion compensation. On the grounds of continuum mechanics laws we introduce a novel score measuring motion reduction in in vivo sequences. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases.
	Address
	Corporate Author				Thesis
	Publisher	Springerlink	Place of Publication	Heidelberg	Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title	Lecture Notes in Computer Science	Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN	978-3-540-74271-5	Medium
	Area		Expedition		Conference
	Notes	IAM;MILAB			Approved	no
	Call Number	IAM @ iam @ GRR2007			Serial	1540
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	Author	Hanne Kause; Aura Hernandez-Sabate; Patricia Marquez; Andrea Fuster; Luc Florack; Hans van Assen; Debora Gil
	Title	Confidence Measures for Assessing the HARP Algorithm in Tagged Magnetic Resonance Imaging			Type	Book Chapter
	Year	2015	Publication	Statistical Atlases and Computational Models of the Heart. Revised selected papers of Imaging and Modelling Challenges 6th International Workshop, STACOM 2015, Held in Conjunction with MICCAI 2015	Abbreviated Journal
	Volume	9534	Issue		Pages	69-79
	Keywords
	Abstract	Cardiac deformation and changes therein have been linked to pathologies. Both can be extracted in detail from tagged Magnetic Resonance Imaging (tMRI) using harmonic phase (HARP) images. Although point tracking algorithms have shown to have high accuracies on HARP images, these vary with position. Detecting and discarding areas with unreliable results is crucial for use in clinical support systems. This paper assesses the capability of two confidence measures (CMs), based on energy and image structure, for detecting locations with reduced accuracy in motion tracking results. These CMs were tested on a database of simulated tMRI images containing the most common artifacts that may affect tracking accuracy. CM performance is assessed based on its capability for HARP tracking error bounding and compared in terms of significant differences detected using a multi comparison analysis of variance that takes into account the most influential factors on HARP tracking performance. Results showed that the CM based on image structure was better suited to detect unreliable optical flow vectors. In addition, it was shown that CMs can be used to detect optical flow vectors with large errors in order to improve the optical flow obtained with the HARP tracking algorithm.
	Address	Munich; Germany; January 2015
	Corporate Author				Thesis
	Publisher	Springer International Publishing	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-319-28711-9	Medium
	Area		Expedition		Conference	STACOM
	Notes	ADAS; IAM; 600.075; 600.076; 600.060; 601.145			Approved	no
	Call Number	Admin @ si @ KHM2015			Serial	2734
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	Author	Fernando Vilariño; Debora Gil; Petia Radeva
	Title	A Novel FLDA Formulation for Numerical Stability Analysis			Type	Book Chapter
	Year	2004	Publication	Recent Advances in Artificial Intelligence Research and Development	Abbreviated Journal
	Volume	113	Issue		Pages	77-84
	Keywords	Supervised Learning; Linear Discriminant Analysis; Numerical Stability; Computer Vision
	Abstract	Fisher Linear Discriminant Analysis (FLDA) is one of the most popular techniques used in classification applying dimensional reduction. The numerical scheme involves the inversion of the within-class scatter matrix, which makes FLDA potentially ill-conditioned when it becomes singular. In this paper we present a novel explicit formulation of FLDA in terms of the eccentricity ratio and eigenvector orientations of the within-class scatter matrix. An analysis of this function will characterize those situations where FLDA response is not reliable because of numerical instability. This can solve common situations of poor classification performance in computer vision.
	Address
	Corporate Author				Thesis
	Publisher	IOS Press	Place of Publication		Editor	J. Vitrià, P. Radeva and I. Aguiló
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN	978-1-58603-466-5	Medium
	Area		Expedition		Conference
	Notes	MV;IAM;MILAB;SIAI			Approved	no
	Call Number	IAM @ iam @ VGR2004			Serial	1663
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	Author	Debora Gil
	Title	Geometric Differential Operators for Shape Modelling			Type	Book Whole
	Year	2004	Publication	PhD Thesis, Universitat Autonoma de Barcelona-CVC	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	Medical imaging feeds research in many computer vision and image processing fields: image filtering, segmentation, shape recovery, registration, retrieval and pattern matching. Because of their low contrast changes and large variety of artifacts and noise, medical imaging processing techniques relying on an analysis of the geometry of image level sets rather than on intensity values result in more robust treatment. From the starting point of treatment of intravascular images, this PhD thesis ad- dresses the design of differential image operators based on geometric principles for a robust shape modelling and restoration. Among all fields applying shape recovery, we approach filtering and segmentation of image objects. For a successful use in real images, the segmentation process should go through three stages: noise removing, shape modelling and shape recovery. This PhD addresses all three topics, but for the sake of algorithms as automated as possible, techniques for image processing will be designed to satisfy three main principles: a) convergence of the iterative schemes to non-trivial states avoiding image degeneration to a constant image and representing smooth models of the originals; b) smooth asymptotic behav- ior ensuring stabilization of the iterative process; c) fixed parameter values ensuring equal (domain free) performance of the algorithms whatever initial images/shapes. Our geometric approach to the generic equations that model the different processes approached enables defining techniques satisfying all the former requirements. First, we introduce a new curvature-based geometric flow for image filtering achieving a good compromise between noise removing and resemblance to original images. Sec- ond, we describe a new family of diffusion operators that restrict their scope to image level curves and serve to restore smooth closed models from unconnected sets of points. Finally, we design a regularization of snake (distance) maps that ensures its smooth convergence towards any closed shape. Experiments show that performance of the techniques proposed overpasses that of state-of-the-art algorithms.
	Address
	Corporate Author				Thesis	Ph.D. thesis
	Publisher	Ediciones Graficas Rey	Place of Publication	Barcelona (Spain)	Editor	Jordi Saludes i Closa;Petia Radeva
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN	84-933652-0-3	Medium	prit
	Area		Expedition		Conference
	Notes	IAM;			Approved	no
	Call Number	IAM @ iam @ GIL2004			Serial	1517
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