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Author Patricia Marquez; Debora Gil ; Aura Hernandez-Sabate edit   pdf
doi  isbn
openurl 
  Title Error Analysis for Lucas-Kanade Based Schemes Type Conference Article
  Year 2012 Publication 9th International Conference on Image Analysis and Recognition Abbreviated Journal  
  Volume (down) 7324 Issue I Pages 184-191  
  Keywords Optical flow, Confidence measure, Lucas-Kanade, Cardiac Magnetic Resonance  
  Abstract Optical flow is a valuable tool for motion analysis in medical imaging sequences. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in medical sequences. This paper presents an error analysis of Lucas-Kanade schemes in terms of intrinsic design errors and numerical stability of the algorithm. Our analysis provides a confidence measure that is naturally correlated to the accuracy of the flow field. Our experiments show the higher predictive value of our confidence measure compared to existing measures.  
  Address Aveiro, Portugal  
  Corporate Author Thesis  
  Publisher Springer-Verlag Berlin Heidelberg Place of Publication Editor  
  Language english Summary Language Original Title  
  Series Editor Campilho, Aurélio and Kamel, Mohamed Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-31294-6 Medium  
  Area Expedition Conference ICIAR  
  Notes IAM Approved no  
  Call Number IAM @ iam @ MGH2012a Serial 1899  
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Author Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru; Miguel Angel Gonzalez Ballester edit   pdf
doi  isbn
openurl 
  Title Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs Type Book Chapter
  Year 2012 Publication Workshop on Computational and Clinical Applications in Abdominal Imaging Abbreviated Journal  
  Volume (down) 7029 Issue Pages 223–230  
  Keywords medial manifolds, abdomen.  
  Abstract Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D
objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial
manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our
method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs,
exploring the use of medial manifolds for the representation of multi-organ relations.
 
  Address Toronto; Canada;  
  Corporate Author Thesis  
  Publisher Springer Link Place of Publication Berlin Editor H. Yoshida et al  
  Language English Summary Language English Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-28556-1 Medium  
  Area Expedition Conference ABDI  
  Notes IAM;MV Approved no  
  Call Number IAM @ iam @ VGB2012 Serial 1834  
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Author Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru edit  openurl
  Title Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs Type Conference Article
  Year 2011 Publication Workshop on Computational and Clinical Applications in Abdominal Imaging Abbreviated Journal  
  Volume (down) 7029 Issue Pages 223-230  
  Keywords  
  Abstract Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations.  
  Address Nice, France  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor In H. Yoshida et al  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference ABDI  
  Notes IAM; MV Approved no  
  Call Number VGB2011 Serial 2036  
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Author Aura Hernandez-Sabate; Debora Gil; David Roche; Monica M. S. Matsumoto; Sergio S. Furuie edit   pdf
url  openurl
  Title Inferring the Performance of Medical Imaging Algorithms Type Conference Article
  Year 2011 Publication 14th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal  
  Volume (down) 6854 Issue Pages 520-528  
  Keywords Validation, Statistical Inference, Medical Imaging Algorithms.  
  Abstract Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence.
 
  Address Sevilla  
  Corporate Author Thesis  
  Publisher Springer-Verlag Berlin Heidelberg Place of Publication Berlin Editor Pedro Real; Daniel Diaz-Pernil; Helena Molina-Abril; Ainhoa Berciano; Walter Kropatsch  
  Language Summary Language Original Title  
  Series Editor Series Title L Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CAIP  
  Notes IAM; ADAS Approved no  
  Call Number IAM @ iam @ HGR2011 Serial 1676  
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Author Jaume Garcia; Debora Gil; Aura Hernandez-Sabate edit   pdf
doi  openurl
  Title Endowing Canonical Geometries to Cardiac Structures Type Book Chapter
  Year 2010 Publication Statistical Atlases And Computational Models Of The Heart Abbreviated Journal  
  Volume (down) 6364 Issue Pages 124-133  
  Keywords  
  Abstract International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view.
 
  Address  
  Corporate Author Thesis  
  Publisher Springer Berlin / Heidelberg Place of Publication Editor Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A.  
  Language Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGH2010b Serial 1515  
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Author Debora Gil; Aura Hernandez-Sabate; Mireia Burnat; Steven Jansen; Jordi Martinez-Vilalta edit   pdf
doi  isbn
openurl 
  Title Structure-Preserving Smoothing of Biomedical Images Type Conference Article
  Year 2009 Publication 13th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal  
  Volume (down) 5702 Issue Pages 427-434  
  Keywords non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography.  
  Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.  
  Address Münster, Germany  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-03766-5 Medium  
  Area Expedition Conference CAIP  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GHB2009 Serial 1527  
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Author Debora Gil; Oriol Rodriguez-Leon; Petia Radeva; Aura Hernandez-Sabate edit   pdf
doi  isbn
openurl 
  Title Assessing Artery Motion Compensation in IVUS Type Book Chapter
  Year 2007 Publication Computer Analysis Of Images And Patterns Abbreviated Journal LNCS  
  Volume (down) 4673 Issue Pages 213-220  
  Keywords validation standards; quality measures; IVUS motion compensation; conservation laws; Fourier development  
  Abstract Cardiac dynamics suppression is a main issue for visual improvement and computation of tissue mechanical properties in IntraVascular UltraSound (IVUS). Although in recent times several motion compensation techniques have arisen, there is a lack of objective evaluation of motion reduction in in vivo pullbacks. We consider that the assessment protocol deserves special attention for the sake of a clinical applicability as reliable as possible. Our work focuses on defining a quality measure and a validation protocol assessing IVUS motion compensation. On the grounds of continuum mechanics laws we introduce a novel score measuring motion reduction in in vivo sequences. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases.  
  Address  
  Corporate Author Thesis  
  Publisher Springerlink Place of Publication Heidelberg Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-3-540-74271-5 Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GRR2007 Serial 1540  
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Author Misael Rosales; Petia Radeva; Oriol Rodriguez; Debora Gil edit   pdf
doi  openurl
  Title Suppression of IVUS Image Rotation. A Kinematic Approach Type Book Chapter
  Year 2005 Publication Functional Imaging and Modeling of the Heart Abbreviated Journal LNCS  
  Volume (down) 3504 Issue Pages 889-892  
  Keywords  
  Abstract IntraVascular Ultrasound (IVUS) is an exploratory technique used in interventional procedures that shows cross section images of arteries and provides qualitative information about the causes and severity of the arterial lumen narrowing. Cross section analysis as well as visualization of plaque extension in a vessel segment during the catheter imaging pullback are the technique main advantages. However, IVUS sequence exhibits a periodic rotation artifact that makes difficult the longitudinal lesion inspection and hinders any segmentation algorithm. In this paper we propose a new kinematic method to estimate and remove the image rotation of IVUS images sequences. Results on several IVUS sequences show good results and prompt some of the clinical applications to vessel dynamics study, and relation to vessel pathology.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Berlin / Heidelberg Place of Publication Editor Frangi, Alejandro and Radeva, Petia and Santos, Andres and Hernandez, Monica  
  Language Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume 3504 Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RRR2005 Serial 1645  
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Author Debora Gil; Petia Radeva edit   pdf
url  doi
isbn  openurl
  Title Curvature Vector Flow to Assure Convergent Deformable Models for Shape Modelling Type Book Chapter
  Year 2003 Publication Energy Minimization Methods In Computer Vision And Pattern Recognition Abbreviated Journal LNCS  
  Volume (down) 2683 Issue Pages 357-372  
  Keywords Initial condition; Convex shape; Non convex analysis; Increase; Segmentation; Gradient; Standard; Standards; Concave shape; Flow models; Tracking; Edge detection; Curvature  
  Abstract Poor convergence to concave shapes is a main limitation of snakes as a standard segmentation and shape modelling technique. The gradient of the external energy of the snake represents a force that pushes the snake into concave regions, as its internal energy increases when new inexion points are created. In spite of the improvement of the external energy by the gradient vector ow technique, highly non convex shapes can not be obtained, yet. In the present paper, we develop a new external energy based on the geometry of the curve to be modelled. By tracking back the deformation of a curve that evolves by minimum curvature ow, we construct a distance map that encapsulates the natural way of adapting to non convex shapes. The gradient of this map, which we call curvature vector ow (CVF), is capable of attracting a snake towards any contour, whatever its geometry. Our experiments show that, any initial snake condition converges to the curve to be modelled in optimal time.  
  Address  
  Corporate Author Thesis  
  Publisher Springer, Berlin Place of Publication Lisbon, PORTUGAL Editor Springer, B.  
  Language Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 3-540-40498-8 Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GIR2003b Serial 1535  
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Author David Roche; Debora Gil; Jesus Giraldo edit  doi
isbn  openurl
  Title Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? Type Book Chapter
  Year 2014 Publication G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology Abbreviated Journal  
  Volume (down) 796 Issue 3 Pages 159-181  
  Keywords β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model  
  Abstract Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Netherlands Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0065-2598 ISBN 978-94-007-7422-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number IAM @ iam @ RGG2014 Serial 2197  
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