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Author |
Aura Hernandez-Sabate |
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Title |
Exploring Arterial Dynamics and Structures in IntraVascular Ultrasound Sequences |
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2009 |
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PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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Cardiovascular diseases are a leading cause of death in developed countries. Most of them are caused by arterial (specially coronary) diseases, mainly caused by plaque accumulation. Such pathology narrows blood flow (stenosis) and affects artery bio- mechanical elastic properties (atherosclerosis). In the last decades, IntraVascular UltraSound (IVUS) has become a usual imaging technique for the diagnosis and follow up of arterial diseases. IVUS is a catheter-based imaging technique which shows a sequence of cross sections of the artery under study. Inspection of a single image gives information about the percentage of stenosis. Meanwhile, inspection of longitudinal views provides information about artery bio-mechanical properties, which can prevent a fatal outcome of the cardiovascular disease. On one hand, dynamics of arteries (due to heart pumping among others) is a major artifact for exploring tissue bio-mechanical properties. On the other one, manual stenosis measurements require a manual tracing of vessel borders, which is a time-consuming task and might suffer from inter-observer variations. This PhD thesis proposes several image processing tools for exploring vessel dy- namics and structures. We present a physics-based model to extract, analyze and correct vessel in-plane rigid dynamics and to retrieve cardiac phase. Furthermore, we introduce a deterministic-statistical method for automatic vessel borders detection. In particular, we address adventitia layer segmentation. An accurate validation pro- tocol to ensure reliable clinical applicability of the methods is a crucial step in any proposal of an algorithm. In this thesis we take special care in designing a valida- tion protocol for each approach proposed and we contribute to the in vivo dynamics validation with a quantitative and objective score to measure the amount of motion suppressed. |
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Ph.D. thesis |
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Ediciones Graficas Rey |
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Debora Gil |
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978-84-937261-6-4 |
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IAM; |
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IAM @ iam @ Her2009 |
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1543 |
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Author |
Aura Hernandez-Sabate |
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Title |
Automatic adventitia segmentation in IntraVascular UltraSound images |
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Report |
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2005 |
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CVC Technical Report |
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85 |
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A usual tool in cardiac disease diagnosis is vessel plaque assessment by analysis of IVUS sequences. Manual detection of lumen-intima, intima-media and media-adventitia vessel borders is the main activity of physicians in the process of plaque quantification. Large variety in vessel border descriptors, as well as, shades, artifacts and blurred response due to ultrasound physical properties troubles automated media-adventitia segmentation. This experimental work presents a solution to such a complex problem. The process blends advanced anisotropic filtering operators and statistic classification techniques, achieving an efficient vessel border modelling strategy. First of all, we introduce the theoretic base of the method. After that, we show the steps of the algorithm, validating the method with statistics that show that the media-adventitia border detection achieves an accuracy in the range of inter-observer variability regardless of plaque nature, vessel geometry and incomplete vessel borders. Finally, we present a little Matlab application to the automatic media-adventitia border. |
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Master's thesis |
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08193 Bellaterra, Barcelona (Spain) |
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IAM @ iam @ Her2005 |
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1544 |
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Oriol Rodriguez-Leon; Josefina Mauri;Eduard Fernandez-Nofrerias; Antonio Tovar; Vicente del Valle; Aura Hernandez-Sabate; Debora Gil; Petia Radeva |
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Utilizacion de la estructura de los campos vectoriales para la deteccion de la Adventicia en imagenes de Ecografia Intracoronaria |
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2004 |
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Revista Española de Cardiología |
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REC |
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57 |
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2 |
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100 |
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MILAB;IAM |
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BCNPCL @ bcnpcl @ RMF2004 |
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566 |
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Author |
Enric Marti; Ferran Poveda; Antoni Gurgui; Jaume Rocarias; Debora Gil; Aura Hernandez-Sabate |
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Una experiencia de estructura, funcionamiento y evaluación de la asignatura de graficos por computador con metodologia de aprendizaje basado en proyectos |
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Miscellaneous |
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2013 |
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IV Congreso Internacional UNIVEST |
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IV Congreso Internacional UNIVEST |
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UNIVEST |
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IAM; ADAS |
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Admin @ si @ MPG2013b |
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2384 |
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Author |
Enric Marti; Jaume Rocarias; Ricardo Toledo; Aura Hernandez-Sabate |
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Title |
Caronte: plataforma Moodle con gestion flexible de grupos. Primeras experiencias en asignaturas de Ingenieria Informatica |
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Miscellaneous |
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2009 |
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15th Jornadas de Enseñanza Universitaria de la Informatica |
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461–468 |
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En este artículo se presenta Caronte, entorno LMS (Learning Management System) basado en Moodle. Una característica importante del entorno es la gestión flexible de grupos en una asignatura. Entendemos por grupo un conjunto de alumnos que realizan un trabajo y uno de ellos entrega la actividad propuesta (práctica, encuesta, etc.) en representación del grupo. Hemos trabajado en la confección de estos grupos, implementando un sistema de inscripción por contraseña.
Caronte ofrece un conjunto de actividades basadas en este concepto de grupo: encuestas, tareas (entrega de trabajos o prácticas), encuestas de autoevaluación y cuestionarios, entre otras.
Basada en nuestra actividad de encuesta, hemos definido una actividad de Control, que permite un cierto feedback electrónico del profesor sobre la actividad de los alumnos.
Finalmente, se presenta un resumen de las experiencias de uso de Caronte sobre asignaturas de Ingeniería Informática en el curso 2007-08. |
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Barcelona, Spain |
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978-84-692-2758-9 |
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JENUI |
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IAM;RV;ADAS |
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IAM @ iam @ MRT2009 |
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1202 |
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Author |
Paula Fritzsche; C.Roig; Ana Ripoll; Emilio Luque; Aura Hernandez-Sabate |
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Title |
A Performance Prediction Methodology for Data-dependent Parallel Applications |
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Conference Article |
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2006 |
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Proceedings of the IEEE International Conference on Cluster Computing |
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1-8 |
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The increase in the use of parallel distributed architectures in order to solve large-scale scientific problems has generated the need for performance prediction for both deterministic applications and non-deterministic applications. In particular, the performance prediction of data dependent programs is an extremely challenging problem because for a specific issue the input datasets may cause different execution times. Generally, a parallel application is characterized as a collection of tasks and their interrelations. If the application is time-critical it is not enough to work with only one value per task, and consequently knowledge of the distribution of task execution times is crucial. The development of a new prediction methodology to estimate the performance of data-dependent parallel applications is the primary target of this study. This approach makes it possible to evaluate the parallel performance of an application without the need of implementation. A real data-dependent arterial structure detection application model is used to apply the methodology proposed. The predicted times obtained using the new methodology for genuine datasets are compared with predicted times that arise from using only one execution value per task. Finally, the experimental study shows that the new methodology generates more precise predictions. |
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IAM @ iam @ FRR2006 |
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1497 |
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Author |
Jaume Garcia; Debora Gil; Luis Badiella; Aura Hernandez-Sabate; Francesc Carreras; Sandra Pujades; Enric Marti |
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Title |
A Normalized Framework for the Design of Feature Spaces Assessing the Left Ventricular Function |
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Journal Article |
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2010 |
Publication |
IEEE Transactions on Medical Imaging |
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TMI |
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29 |
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3 |
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733-745 |
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A through description of the left ventricle functionality requires combining complementary regional scores. A main limitation is the lack of multiparametric normality models oriented to the assessment of regional wall motion abnormalities (RWMA). This paper covers two main topics involved in RWMA assessment. We propose a general framework allowing the fusion and comparison across subjects of different regional scores. Our framework is used to explore which combination of regional scores (including 2-D motion and strains) is better suited for RWMA detection. Our statistical analysis indicates that for a proper (within interobserver variability) identification of RWMA, models should consider motion and extreme strains. |
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0278-0062 |
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IAM @ iam @ GGH2010b |
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1507 |
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Author |
Jaume Garcia; Debora Gil; Aura Hernandez-Sabate |
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Title |
Endowing Canonical Geometries to Cardiac Structures |
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2010 |
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Statistical Atlases And Computational Models Of The Heart |
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6364 |
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124-133 |
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International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view. |
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Springer Berlin / Heidelberg |
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Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A. |
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Lecture Notes in Computer Science |
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LNCS |
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IAM @ iam @ GGH2010b |
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1515 |
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Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti |
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Title |
Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy |
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Conference Article |
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2010 |
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8th Medical Imaging |
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7623 |
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762304 |
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304 |
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Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature. |
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SPIE |
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IAM @ iam @ GGH2010a |
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1522 |
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Author |
Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva |
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Title |
A Deterministic-Statistic Adventitia Detection in IVUS Images |
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Conference Article |
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2005 |
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ESC Congress |
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Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation |
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Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles. |
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Stockholm; Sweden; September 2005 |
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IAM @ iam @ RMF2005a |
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1523 |
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