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Author |
Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru; Miguel Angel Gonzalez Ballester |
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Title |
Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs |
Type |
Book Chapter |
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Year |
2012 |
Publication |
Workshop on Computational and Clinical Applications in Abdominal Imaging |
Abbreviated Journal |
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Volume |
7029 |
Issue |
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Pages |
223–230 |
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Keywords |
medial manifolds, abdomen. |
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Abstract |
Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D
objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial
manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our
method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs,
exploring the use of medial manifolds for the representation of multi-organ relations. |
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Address |
Toronto; Canada; |
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Publisher |
Springer Link |
Place of Publication |
Berlin |
Editor |
H. Yoshida et al |
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Language |
English |
Summary Language |
English |
Original Title |
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Series Editor |
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Series Title |
Lecture Notes in Computer Science |
Abbreviated Series Title |
LNCS |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0302-9743 |
ISBN |
978-3-642-28556-1 |
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Expedition |
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Conference |
ABDI |
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Notes |
IAM;MV |
Approved |
no |
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Call Number |
IAM @ iam @ VGB2012 |
Serial |
1834 |
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Permanent link to this record |
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Author |
Alberto Hidalgo; Ferran Poveda; Enric Marti;Debora Gil;Albert Andaluz; Francesc Carreras; Manuel Ballester |
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Title |
Evidence of continuous helical structure of the cardiac ventricular anatomy assessed by diffusion tensor imaging magnetic resonance multiresolution tractography |
Type |
Journal Article |
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Year |
2012 |
Publication |
European Radiology |
Abbreviated Journal |
ECR |
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Volume |
3 |
Issue |
1 |
Pages |
361-362 |
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Keywords |
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Abstract |
Deep understanding of myocardial structure linking morphology and func- tion of the heart would unravel crucial knowledge for medical and surgical clinical procedures and studies. Diffusion tensor MRI provides a discrete measurement of the 3D arrangement of myocardial fibres by the observation of local anisotropic
diffusion of water molecules in biological tissues. In this work, we present a multi- scale visualisation technique based on DT-MRI streamlining capable of uncovering additional properties of the architectural organisation of the heart. Methods and Materials: We selected the John Hopkins University (JHU) Canine Heart Dataset, where the long axis cardiac plane is aligned with the scanner’s Z- axis. Their equipment included a 4-element passed array coil emitting a 1.5 T. For DTI acquisition, a 3D-FSE sequence is apply. We used 200 seeds for full-scale tractography, while we applied a MIP mapping technique for simplified tractographic reconstruction. In this case, we reduced each DTI 3D volume dimensions by order- two magnitude before streamlining.
Our simplified tractographic reconstruction method keeps the main geometric features of fibres, allowing for an easier identification of their global morphological disposition, including the ventricular basal ring. Moreover, we noticed a clearly visible helical disposition of the myocardial fibres, in line with the helical myocardial band ventricular structure described by Torrent-Guasp. Finally, our simplified visualisation with single tracts identifies the main segments of the helical ventricular architecture.
DT-MRI makes possible the identification of a continuous helical architecture of the myocardial fibres, which validates Torrent-Guasp’s helical myocardial band ventricular anatomical model. |
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Address |
Viena, Austria |
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Publisher |
Springer Link |
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Edition |
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ISSN |
1869-4101 |
ISBN |
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Notes |
IAM |
Approved |
no |
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Call Number |
IAM @ iam @ HPM2012 |
Serial |
1858 |
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Permanent link to this record |
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Author |
Patricia Marquez; Debora Gil; Aura Hernandez-Sabate; Daniel Kondermann |
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Title |
When Is A Confidence Measure Good Enough? |
Type |
Conference Article |
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Year |
2013 |
Publication |
9th International Conference on Computer Vision Systems |
Abbreviated Journal |
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Volume |
7963 |
Issue |
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Pages |
344-353 |
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Keywords |
Optical flow, confidence measure, performance evaluation |
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Abstract |
Confidence estimation has recently become a hot topic in image processing and computer vision.Yet, several definitions exist of the term “confidence” which are sometimes used interchangeably. This is a position paper, in which we aim to give an overview on existing definitions,
thereby clarifying the meaning of the used terms to facilitate further research in this field. Based on these clarifications, we develop a theory to compare confidence measures with respect to their quality. |
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Address |
St Petersburg; Russia; July 2013 |
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Publisher |
Springer Link |
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Abbreviated Series Title |
LNCS |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0302-9743 |
ISBN |
978-3-642-39401-0 |
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Conference |
ICVS |
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Notes |
IAM;ADAS; 600.044; 600.057; 600.060; 601.145 |
Approved |
no |
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Call Number |
IAM @ iam @ MGH2013a |
Serial |
2218 |
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Permanent link to this record |
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Author |
Debora Gil; Oriol Ramos Terrades; Raquel Perez |
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Title |
Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution |
Type |
Book Chapter |
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Year |
2021 |
Publication |
Extended Abstracts GEOMVAP 2019, Trends in Mathematics 15 |
Abbreviated Journal |
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Volume |
15 |
Issue |
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Pages |
89–93 |
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Keywords |
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Abstract |
Abnormalities in radiomic measures correlate to genomic alterations prone to alter the outcome of personalized anti-cancer treatments. TOPiomics is a new method for the early detection of variations in tumor imaging phenotype from a topological structure in multi-view radiomic spaces. |
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Publisher |
Springer Nature |
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Notes |
IAM; DAG; 600.120; 600.145; 600.139 |
Approved |
no |
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Call Number |
Admin @ si @ GRP2021 |
Serial |
3594 |
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Permanent link to this record |
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Author |
Francesc Carreras; Jaume Garcia; Debora Gil; Sandra Pujadas; Chi ho Lion; R.Suarez-Arias; R.Leta; Xavier Alomar; Manuel Ballester; Guillem Pons-Llados |
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Title |
Left ventricular torsion and longitudinal shortening: two fundamental components of myocardial mechanics assessed by tagged cine-MRI in normal subjects |
Type |
Journal Article |
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Year |
2012 |
Publication |
International Journal of Cardiovascular Imaging |
Abbreviated Journal |
IJCI |
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Volume |
28 |
Issue |
2 |
Pages |
273-284 |
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Keywords |
Magnetic resonance imaging (MRI); Tagging MRI; Cardiac mechanics; Ventricular torsion |
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Abstract |
Cardiac magnetic resonance imaging (Cardiac MRI) has become a gold standard diagnostic technique for the assessment of cardiac mechanics, allowing the non-invasive calculation of left ventric- ular long axis longitudinal shortening (LVLS) and absolute myocardial torsion (AMT) between basal and apical left ventricular slices, a movement directly related to the helicoidal anatomic disposition of the myocardial fibers. The aim of this study is to determine AMT and LVLS behaviour and normal values from a group of healthy subjects. A group of 21 healthy volunteers (15 males) (age: 23–55 y.o., mean:30.7 ± 7.5) were prospectively included in an obser- vational study by Cardiac MRI. Left ventricular rotation (degrees) was calculated by custom-made software (Harmonic Phase Flow) in consecutive LV short axis planes tagged cine-MRI sequences. AMT was determined from the difference between basal and apical planes LV rotations. LVLS (%) was determined from the LV longitudinal and horizontal axis cine-MRI images. All the 21 cases studied were interpretable, although in three cases the value of the LV apical rotation could not be determined. The mean rotation of the basal and apical planes at end-systole were -3.71° ± 0.84° and 6.73° ± 1.69° (n:18) respectively, resulting in a LV mean AMT of 10.48° ± 1.63° (n:18). End-systolic mean LVLS was 19.07 ± 2.71%. Cardiac MRI allows for the calculation of AMT and LVLS, fundamental functional components of the ventricular twist mechanics conditioned, in turn, by the anatomical helical layout of the myocardial fibers. These values provide complementary information about systolic ventricular function in relation to the traditional parameters used in daily practice. |
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Publisher |
Springer Netherlands |
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Series Editor |
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Edition |
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ISSN |
1569-5794 |
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Notes |
IAM; |
Approved |
no |
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Call Number |
IAM @ iam @ CGG2012 |
Serial |
1496 |
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Permanent link to this record |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? |
Type |
Book Chapter |
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Year |
2014 |
Publication |
G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology |
Abbreviated Journal |
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Volume |
796 |
Issue |
3 |
Pages |
159-181 |
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Keywords |
β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model |
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Abstract |
Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists. |
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Publisher |
Springer Netherlands |
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Edition |
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ISSN |
0065-2598 |
ISBN |
978-94-007-7422-3 |
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Notes |
IAM; 600.075 |
Approved |
no |
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Call Number |
IAM @ iam @ RGG2014 |
Serial |
2197 |
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Permanent link to this record |
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Author |
Debora Gil; David Roche; Agnes Borras; Jesus Giraldo |
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Title |
Terminating Evolutionary Algorithms at their Steady State |
Type |
Journal Article |
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Year |
2015 |
Publication |
Computational Optimization and Applications |
Abbreviated Journal |
COA |
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Volume |
61 |
Issue |
2 |
Pages |
489-515 |
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Keywords |
Evolutionary algorithms; Termination condition; Steady state; Differential evolution |
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Abstract |
Assessing the reliability of termination conditions for evolutionary algorithms (EAs) is of prime importance. An erroneous or weak stop criterion can negatively affect both the computational effort and the final result. We introduce a statistical framework for assessing whether a termination condition is able to stop an EA at its steady state, so that its results can not be improved anymore. We use a regression model in order to determine the requirements ensuring that a measure derived from EA evolving population is related to the distance to the optimum in decision variable space. Our framework is analyzed across 24 benchmark test functions and two standard termination criteria based on function fitness value in objective function space and EA population decision variable space distribution for the differential evolution (DE) paradigm. Results validate our framework as a powerful tool for determining the capability of a measure for terminating EA and the results also identify the decision variable space distribution as the best-suited for accurately terminating DE in real-world applications. |
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Publisher |
Springer US |
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Edition |
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ISSN |
0926-6003 |
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Notes |
IAM; 600.044; 605.203; 600.060; 600.075 |
Approved |
no |
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Call Number |
Admin @ si @ GRB2015 |
Serial |
2560 |
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Permanent link to this record |
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Author |
Debora Gil; Petia Radeva |
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Title |
Curvature Vector Flow to Assure Convergent Deformable Models for Shape Modelling |
Type |
Book Chapter |
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Year |
2003 |
Publication |
Energy Minimization Methods In Computer Vision And Pattern Recognition |
Abbreviated Journal |
LNCS |
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Volume |
2683 |
Issue |
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Pages |
357-372 |
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Keywords |
Initial condition; Convex shape; Non convex analysis; Increase; Segmentation; Gradient; Standard; Standards; Concave shape; Flow models; Tracking; Edge detection; Curvature |
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Abstract |
Poor convergence to concave shapes is a main limitation of snakes as a standard segmentation and shape modelling technique. The gradient of the external energy of the snake represents a force that pushes the snake into concave regions, as its internal energy increases when new inexion points are created. In spite of the improvement of the external energy by the gradient vector ow technique, highly non convex shapes can not be obtained, yet. In the present paper, we develop a new external energy based on the geometry of the curve to be modelled. By tracking back the deformation of a curve that evolves by minimum curvature ow, we construct a distance map that encapsulates the natural way of adapting to non convex shapes. The gradient of this map, which we call curvature vector ow (CVF), is capable of attracting a snake towards any contour, whatever its geometry. Our experiments show that, any initial snake condition converges to the curve to be modelled in optimal time. |
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Publisher |
Springer, Berlin |
Place of Publication |
Lisbon, PORTUGAL |
Editor |
Springer, B. |
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Series Editor |
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Series Title |
Lecture Notes in Computer Science |
Abbreviated Series Title |
LNCS |
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Edition |
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ISSN |
0302-9743 |
ISBN |
3-540-40498-8 |
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Notes |
IAM;MILAB |
Approved |
no |
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Call Number |
IAM @ iam @ GIR2003b |
Serial |
1535 |
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Permanent link to this record |
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Author |
Patricia Marquez;Debora Gil;Aura Hernandez-Sabate |
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Title |
A Complete Confidence Framework for Optical Flow |
Type |
Conference Article |
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Year |
2012 |
Publication |
12th European Conference on Computer Vision – Workshops and Demonstrations |
Abbreviated Journal |
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Volume |
7584 |
Issue |
2 |
Pages |
124-133 |
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Keywords |
Optical flow, confidence measures, sparsification plots, error prediction plots |
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Abstract |
Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations. |
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Publisher |
Springer-Verlag |
Place of Publication |
Florence, Italy, October 7-13, 2012 |
Editor |
Andrea Fusiello, Vittorio Murino ,Rita Cucchiara |
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LNCS |
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ISBN |
978-3-642-33867-0 |
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Conference |
ECCVW |
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Notes |
IAM;ADAS; |
Approved |
no |
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Call Number |
IAM @ iam @ MGH2012b |
Serial |
1991 |
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Permanent link to this record |
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Author |
Aura Hernandez-Sabate; Debora Gil; David Roche; Monica M. S. Matsumoto; Sergio S. Furuie |
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Title |
Inferring the Performance of Medical Imaging Algorithms |
Type |
Conference Article |
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Year |
2011 |
Publication |
14th International Conference on Computer Analysis of Images and Patterns |
Abbreviated Journal |
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Volume |
6854 |
Issue |
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Pages |
520-528 |
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Keywords |
Validation, Statistical Inference, Medical Imaging Algorithms. |
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Abstract |
Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence. |
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Address |
Sevilla |
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Publisher |
Springer-Verlag Berlin Heidelberg |
Place of Publication |
Berlin |
Editor |
Pedro Real; Daniel Diaz-Pernil; Helena Molina-Abril; Ainhoa Berciano; Walter Kropatsch |
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L |
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LNCS |
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CAIP |
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Notes |
IAM; ADAS |
Approved |
no |
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Call Number |
IAM @ iam @ HGR2011 |
Serial |
1676 |
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Permanent link to this record |