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Author Mariano Vazquez; Ruth Aris; Guillaume Hozeaux; R.Aubry; P.Villar;Jaume Garcia ; Debora Gil; Francesc Carreras edit   pdf
url  doi
openurl 
  Title A massively parallel computational electrophysiology model of the heart Type Journal Article
  Year 2011 Publication (down) International Journal for Numerical Methods in Biomedical Engineering Abbreviated Journal IJNMBE  
  Volume 27 Issue Pages 1911-1929  
  Keywords computational electrophysiology; parallelization; finite element methods  
  Abstract This paper presents a patient-sensitive simulation strategy capable of using the most efficient way the high-performance computational resources. The proposed strategy directly involves three different players: Computational Mechanics Scientists (CMS), Image Processing Scientists and Cardiologists, each one mastering its own expertise area within the project. This paper describes the general integrative scheme but focusing on the CMS side presents a massively parallel implementation of computational electrophysiology applied to cardiac tissue simulation. The paper covers different angles of the computational problem: equations, numerical issues, the algorithm and parallel implementation. The proposed methodology is illustrated with numerical simulations testing all the different possibilities, ranging from small domains up to very large ones. A key issue is the almost ideal scalability not only for large and complex problems but also for medium-size meshes. The explicit formulation is particularly well suited for solving this highly transient problems, with very short time-scale.  
  Address Swansea (UK)  
  Corporate Author John Wiley & Sons, Ltd. Thesis  
  Publisher John Wiley & Sons, Ltd. Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ VAH2011 Serial 1198  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil; Jaume Garcia; Enric Marti edit   pdf
doi  openurl
  Title Image-based Cardiac Phase Retrieval in Intravascular Ultrasound Sequences Type Journal Article
  Year 2011 Publication (down) IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control Abbreviated Journal T-UFFC  
  Volume 58 Issue 1 Pages 60-72  
  Keywords 3-D exploring; ECG; band-pass filter; cardiac motion; cardiac phase retrieval; coronary arteries; electrocardiogram signal; image intensity local mean evolution; image-based cardiac phase retrieval; in vivo pullbacks acquisition; intravascular ultrasound sequences; longitudinal motion; signal extrema; time 36 ms; band-pass filters; biomedical ultrasonics; cardiovascular system; electrocardiography; image motion analysis; image retrieval; image sequences; medical image processing; ultrasonic imaging  
  Abstract Longitudinal motion during in vivo pullbacks acquisition of intravascular ultrasound (IVUS) sequences is a major artifact for 3-D exploring of coronary arteries. Most current techniques are based on the electrocardiogram (ECG) signal to obtain a gated pullback without longitudinal motion by using specific hardware or the ECG signal itself. We present an image-based approach for cardiac phase retrieval from coronary IVUS sequences without an ECG signal. A signal reflecting cardiac motion is computed by exploring the image intensity local mean evolution. The signal is filtered by a band-pass filter centered at the main cardiac frequency. Phase is retrieved by computing signal extrema. The average frame processing time using our setup is 36 ms. Comparison to manually sampled sequences encourages a deeper study comparing them to ECG signals.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0885-3010 ISBN Medium  
  Area Expedition Conference  
  Notes IAM;ADAS Approved no  
  Call Number IAM @ iam @ HGG2011 Serial 1546  
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Author Jaume Garcia; Debora Gil; Luis Badiella; Aura Hernandez-Sabate; Francesc Carreras; Sandra Pujades; Enric Marti edit   pdf
doi  openurl
  Title A Normalized Framework for the Design of Feature Spaces Assessing the Left Ventricular Function Type Journal Article
  Year 2010 Publication (down) IEEE Transactions on Medical Imaging Abbreviated Journal TMI  
  Volume 29 Issue 3 Pages 733-745  
  Keywords  
  Abstract A through description of the left ventricle functionality requires combining complementary regional scores. A main limitation is the lack of multiparametric normality models oriented to the assessment of regional wall motion abnormalities (RWMA). This paper covers two main topics involved in RWMA assessment. We propose a general framework allowing the fusion and comparison across subjects of different regional scores. Our framework is used to explore which combination of regional scores (including 2-D motion and strains) is better suited for RWMA detection. Our statistical analysis indicates that for a proper (within interobserver variability) identification of RWMA, models should consider motion and extreme strains.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0278-0062 ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGH2010b Serial 1507  
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Author Enric Marti; Jaume Rocarias; Debora Gil; Aura Hernandez-Sabate; Jaume Garcia; Carme Julia; Marc Vivet edit   pdf
openurl 
  Title Uso de recursos virtuales en Aprendizaje Basado en Proyectos. Una experiencia en la asignatura de Gráficos por Computador Type Miscellaneous
  Year 2009 Publication (down) I Congreso de Docencia Universitaria Abbreviated Journal  
  Volume Issue Pages  
  Keywords Aprendizaje Basado en Proyectos; Project Based Learning; Aprendizaje Cooperativo; Recursos Virtuales para el Aprendizaje Cooperativo; Moodle  
  Abstract Presentamos una experiencia en Aprendizaje Basado en Proyectos (ABP) realizada los últimos cuatro años en Gráficos por Computador 2, asignatura de Ingeniería Informática, de la Escuela Técnica Superior de Ingeniería (ETSE) de la Universidad Autónoma de Barcelona (UAB). Utilizamos un entorno Moodle adaptado por nosotros llamado Caronte para poder gestionar la documentación generada en ABP. Primero se presenta la asignatura, basada en dos itinerarios para cursarla: ABP y TPPE (Teoría, Problemas, Prácticas, Examen). El alumno debe escoger uno de ellos. Ambos itinerarios generan una cantidad importante de documentación (entregas de trabajos y prácticas, correcciones, ejercicios, etc.) a gestionar. En la comunicación presentamos los espacios electrónicos Moodle de ambos itinerarios. Finalmente, mostramos los resultados de encuestas realizadas a los alumnos para finalmente exponer las conclusiones de la experiencia en ABP y el uso de Moodle, así como plantear mejoras y temas de discusión.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Vigo (Spain) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;ADAS; Approved no  
  Call Number IAM @ iam @ MRG2009a Serial 1602  
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Author Albert Andaluz; Francesc Carreras; Debora Gil; Jaume Garcia edit   pdf
url  openurl
  Title Una aplicació amigable pel càlcul de indicadors clínics del ventricle esquerre Type Miscellaneous
  Year 2010 Publication (down) Forum Biocat 2010 Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract  
  Address Lonja de Mar,Barcelona (Spain)  
  Corporate Author CVC Thesis  
  Publisher Biocat Place of Publication Barcelona Editor  
  Language Catalan Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ ACG2010 Serial 1483  
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Author Jaume Garcia edit   pdf
openurl 
  Title Generalized Active Shape Models Applied to Cardiac Function Analysis Type Report
  Year 2004 Publication (down) CVC Technical Report Abbreviated Journal  
  Volume Issue 78 Pages  
  Keywords Cardiac Analysis; Deformable Models; Active Contour Models; Active Shape Models; Tagged MRI; HARP; Contrast Echocardiography.  
  Abstract Medical imaging is very useful in the assessment and treatment of many diseases. To deal with the great amount of data provided by imaging scanners and extract quantitative information that physicians can interpret, many analysis algorithms have been developed. Any process of analysis always consists of a first step of segmenting some particular structure. In medical imaging, structures are not always well defined and suffer from noise artifacts thus, ordinary segmentation methods are not well suited. The ones that seem to give better results are those based on deformable models. Nevertheless, despite their capability of mixing image features together with smoothness constraints that may compensate for image irregularities, these are naturally local methods, i. e., each node of the active contour evolve taking into account information about its neighbors and some other weak constraints about flexibility and smoothness, but not about the global shape that they should find. Due to the fact that structures to be segmented are the same for all cases but with some inter and intra-patient variation, the incorporation of a priori knowledge about shape in the segmentation method will provide robustness to it. Active Shape Models is an algorithm based on the creation of a shape model called Point Distribution Model. It performs a segmentation using only shapes similar than those previously learned from a training set that capture most of the variation presented by the structure. This algorithm works by updating shape nodes along a normal segment which often can be too restrictive. For this reason we propose a generalization of this algorithm that we call Generalized Active Shape Models and fully integrates the a priori knowledge given by the Point Distribution Model with deformable models or any other appropriate segmentation method. Two different applications to cardiac imaging of this generalized method are developed and promising results are shown.  
  Address CVC (UAB)  
  Corporate Author Thesis Master's thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ Gar2004 Serial 1513  
Permanent link to this record
 

 
Author Jaume Garcia; Joel Barajas; Francesc Carreras; Sandra Pujades; Petia Radeva edit   pdf
doi  isbn
openurl 
  Title An intuitive validation technique to compare local versus global tagged MRI analysis Type Conference Article
  Year 2005 Publication (down) Computers In Cardiology Abbreviated Journal  
  Volume 32 Issue Pages 29–32  
  Keywords  
  Abstract Myocardium appears as a uniform tissue that seen in convectional Magnetic Resonance Images (MRI) shows just the contractile part of its movement. MR Tagging is a unique imaging technique that prints a grid over the tissue which moves according to the underlying movement of the myocardium revealing the true deformation of the cardiac muscle. Optical flow techniques based on spectral information estimate tissue displacement by analyzing information encoded in the phase maps which can be obtained using, local (Gabor) and global (HARP) methods. In this paper we compare both in synthetic and real Tagged MR sequences. We conclude that local method is slightly more accurate than the global one. On the other hand, global method is more efficient as it is much faster and less parameters have to be taken into account  
  Address Lyon (France)  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 0-7803-9337-6 Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GBC2005 Serial 639  
Permanent link to this record
 

 
Author David Rotger; Misael Rosales; Jaume Garcia; Oriol Pujol ; Josefina Mauri; Petia Radeva edit   pdf
openurl 
  Title Active Vessel: A New Multimedia Workstation for Intravascular Ultrasound and Angiography Fusion Type Journal Article
  Year 2003 Publication (down) Computers in Cardiology Abbreviated Journal  
  Volume 30 Issue Pages 65-68  
  Keywords  
  Abstract AcriveVessel is a new multimedia workstation which enables the visualization, acquisition and handling of both image modalities, on- and ofline. It enables DICOM v3.0 decompression and browsing, video acquisition,repmduction and storage for IntraVascular UltraSound (IVUS) and angiograms with their corresponding ECG,automatic catheter segmentation in angiography images (using fast marching algorithm). BSpline models definition for vessel layers on IVUS images sequence and an extensively validated tool to fuse information. This approach defines the correspondence of every IVUS image with its correspondent point in the angiogram and viceversa. The 3 0 reconstruction of the NUS catheterhessel enables real distance measurements as well as threedimensional visualization showing vessel tortuosity in the space.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB;HuPBA Approved no  
  Call Number IAM @ iam @ RRG2003 Serial 1647  
Permanent link to this record
 

 
Author Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux edit   pdf
url  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
  Year 2008 Publication (down) 8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance.  
  Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Venezia (Italia) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN B-31470-08 ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGV2008c Serial 1521  
Permanent link to this record
 

 
Author Debora Gil; Jaume Garcia; Mariano Vazquez; Ruth Aris; Guilleaume Houzeaux edit   pdf
isbn  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
  Year 2008 Publication (down) 8th World Congress on Computational Mechanichs (WCCM8) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance.  
  Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.
 
  Address Venice; Italy  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 9788496736559 Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ GGV2008b Serial 993  
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