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Author Jaume Garcia; Debora Gil; Sandra Pujades; Francesc Carreras edit   pdf
doi  openurl
  Title A Variational Framework for Assessment of the Left Ventricle Motion Type Journal Article
  Year 2008 Publication International Journal Mathematical Modelling of Natural Phenomena Abbreviated Journal  
  Volume 3 Issue 6 Pages (down) 76-100  
  Keywords Key words: Left Ventricle Dynamics, Ventricular Torsion, Tagged Magnetic Resonance, Motion Tracking, Variational Framework, Gabor Transform.  
  Abstract Impairment of left ventricular contractility due to cardiovascular diseases is reflected in left ventricle (LV) motion patterns. An abnormal change of torsion or long axis shortening LV values can help with the diagnosis and follow-up of LV dysfunction. Tagged Magnetic Resonance (TMR) is a widely spread medical imaging modality that allows estimation of the myocardial tissue local deformation. In this work, we introduce a novel variational framework for extracting the left ventricle dynamics from TMR sequences. A bi-dimensional representation space of TMR images given by Gabor filter banks is defined. Tracking of the phases of the Gabor response is combined using a variational framework which regularizes the deformation field just at areas where the Gabor amplitude drops, while restoring the underlying motion otherwise. The clinical applicability of the proposed method is illustrated by extracting normality models of the ventricular torsion from 19 healthy subjects.  
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  Corporate Author Thesis  
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  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGC2008a Serial 1058  
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Author H. Martin Kjer; Jens Fagertun; Sergio Vera; Debora Gil; Miguel Angel Gonzalez Ballester; Rasmus R. Paulsena edit   pdf
url  openurl
  Title Free-form image registration of human cochlear uCT data using skeleton similarity as anatomical prior Type Journal Article
  Year 2016 Publication Patter Recognition Letters Abbreviated Journal PRL  
  Volume 76 Issue 1 Pages (down) 76-82  
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  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.060 Approved no  
  Call Number Admin @ si @ MFV2017b Serial 2941  
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Author Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Francesca Vidal; Zaida Sarrate edit   pdf
isbn  openurl
  Title Noves perspectives en l estudi de la territorialitat cromosomica de cel·lules germinals masculines: estudis tridimensionals Type Journal
  Year 2017 Publication Biologia de la Reproduccio Abbreviated Journal JBR  
  Volume 15 Issue Pages (down) 73-78  
  Keywords  
  Abstract In somatic cells, chromosomes occupy specific nuclear regions called chromosome territories which are involved in the
maintenance and regulation of the genome. Preliminary data in male germ cells also suggest the importance of chromosome
territoriality in cell functionality. Nevertheless, the specific characteristics of testicular tissue (presence of different
cell types with different morphological characteristics, in different stages of development and with different ploidy)
makes difficult to achieve conclusive results. In this study we have developed a methodology to approach the threedimensional
study of all chromosome territories in male germ cells from C57BL/6J mice (Mus musculus). The method
includes the following steps: i) Optimized cell fixation to obtain an optimal preservation of the three-dimensionality cell
morphology, ii) Chromosome identification by FISH (Chromoprobe Multiprobe® OctoChrome™ Murine System; Cytocell)
and confocal microscopy (TCS-SP5, Leica Microsystems), iii) Cell type identification by immunofluorescence
iv) Image analysis using Matlab scripts, v) Numerical data extraction related to chromosome features, chromosome
radial position and chromosome relative position. This methodology allows the unequivocally identification and the
analysis of the chromosome territories of all spermatogenic stages. Results will provide information about the features
that determine chromosomal position, preferred associations between chromosomes, and the relationship between chromosome
positioning and genome regulation.
 
  Address  
  Corporate Author Thesis  
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  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-84-697-3767-5 Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 600.145 Approved no  
  Call Number Admin @ si @ SBG2017c Serial 2961  
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Author Hanne Kause; Aura Hernandez-Sabate; Patricia Marquez; Andrea Fuster; Luc Florack; Hans van Assen; Debora Gil edit   pdf
doi  isbn
openurl 
  Title Confidence Measures for Assessing the HARP Algorithm in Tagged Magnetic Resonance Imaging Type Book Chapter
  Year 2015 Publication Statistical Atlases and Computational Models of the Heart. Revised selected papers of Imaging and Modelling Challenges 6th International Workshop, STACOM 2015, Held in Conjunction with MICCAI 2015 Abbreviated Journal  
  Volume 9534 Issue Pages (down) 69-79  
  Keywords  
  Abstract Cardiac deformation and changes therein have been linked to pathologies. Both can be extracted in detail from tagged Magnetic Resonance Imaging (tMRI) using harmonic phase (HARP) images. Although point tracking algorithms have shown to have high accuracies on HARP images, these vary with position. Detecting and discarding areas with unreliable results is crucial for use in clinical support systems. This paper assesses the capability of two confidence measures (CMs), based on energy and image structure, for detecting locations with reduced accuracy in motion tracking results. These CMs were tested on a database of simulated tMRI images containing the most common artifacts that may affect tracking accuracy. CM performance is assessed based on its capability for HARP tracking error bounding and compared in terms of significant differences detected using a multi comparison analysis of variance that takes into account the most influential factors on HARP tracking performance. Results showed that the CM based on image structure was better suited to detect unreliable optical flow vectors. In addition, it was shown that CMs can be used to detect optical flow vectors with large errors in order to improve the optical flow obtained with the HARP tracking algorithm.  
  Address Munich; Germany; January 2015  
  Corporate Author Thesis  
  Publisher Springer International Publishing Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-319-28711-9 Medium  
  Area Expedition Conference STACOM  
  Notes ADAS; IAM; 600.075; 600.076; 600.060; 601.145 Approved no  
  Call Number Admin @ si @ KHM2015 Serial 2734  
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Author Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit   pdf
openurl 
  Title On the usefulness of supervised learning for vessel border detection in IntraVascular Imaging Type Conference Article
  Year 2005 Publication Proceeding of the 2005 conference on Artificial Intelligence Research and Development Abbreviated Journal  
  Volume Issue Pages (down) 67-74  
  Keywords classification; vessel border modelling; IVUS  
  Abstract IntraVascular UltraSound (IVUS) imaging is a useful tool in diagnosis of cardiac diseases since sequences completely show the morphology of coronary vessels. Vessel borders detection, especially the external adventitia layer, plays a central role in morphological measures and, thus, their segmentation feeds development of medical imaging techniques. Deterministic approaches fail to yield optimal results due to the large amount of IVUS artifacts and vessel borders descriptors. We propose using classification techniques to learn the set of descriptors and parameters that best detect vessel borders. Statistical hypothesis test on the error between automated detections and manually traced borders by 4 experts show that our detections keep within inter-observer variability.  
  Address  
  Corporate Author Thesis  
  Publisher IOS Press Place of Publication Amsterdam, The Netherlands Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ HGR2005c Serial 1549  
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Author Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva edit   pdf
doi  openurl
  Title A Deterministic-Statistic Adventitia Detection in IVUS Images Type Conference Article
  Year 2005 Publication 3rd International workshop on International Workshop on Functional Imaging and Modeling of the Heart Abbreviated Journal  
  Volume Issue Pages (down) 65-74  
  Keywords Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation  
  Abstract Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.  
  Address Barcelona; June 2005  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference FIMH  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RMF2005 Serial 1524  
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Author Debora Gil; Rosa Maria Ortiz; Carles Sanchez; Antoni Rosell edit   pdf
doi  openurl
  Title Objective endoscopic measurements of central airway stenosis. A pilot study Type Journal Article
  Year 2018 Publication Respiration Abbreviated Journal RES  
  Volume 95 Issue Pages (down) 63–69  
  Keywords Bronchoscopy; Tracheal stenosis; Airway stenosis; Computer-assisted analysis  
  Abstract Endoscopic estimation of the degree of stenosis in central airway obstruction is subjective and highly variable. Objective: To determine the benefits of using SENSA (System for Endoscopic Stenosis Assessment), an image-based computational software, for obtaining objective stenosis index (SI) measurements among a group of expert bronchoscopists and general pulmonologists. Methods: A total of 7 expert bronchoscopists and 7 general pulmonologists were enrolled to validate SENSA usage. The SI obtained by the physicians and by SENSA were compared with a reference SI to set their precision in SI computation. We used SENSA to efficiently obtain this reference SI in 11 selected cases of benign stenosis. A Web platform with three user-friendly microtasks was designed to gather the data. The users had to visually estimate the SI from videos with and without contours of the normal and the obstructed area provided by SENSA. The users were able to modify the SENSA contours to define the reference SI using morphometric bronchoscopy. Results: Visual SI estimation accuracy was associated with neither bronchoscopic experience (p = 0.71) nor the contours of the normal and the obstructed area provided by the system (p = 0.13). The precision of the SI by SENSA was 97.7% (95% CI: 92.4-103.7), which is significantly better than the precision of the SI by visual estimation (p < 0.001), with an improvement by at least 15%. Conclusion: SENSA provides objective SI measurements with a precision of up to 99.5%, which can be calculated from any bronchoscope using an affordable scalable interface. Providing normal and obstructed contours on bronchoscopic videos does not improve physicians' visual estimation of the SI.  
  Address  
  Corporate Author Thesis  
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  Language Summary Language Original Title  
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  Area Expedition Conference  
  Notes IAM; 600.075; 600.096; 600.145 Approved no  
  Call Number Admin @ si @ GOS2018 Serial 3043  
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Author Debora Gil; Ruth Aris; Agnes Borras; Esmitt Ramirez; Rafael Sebastian; Mariano Vazquez edit   pdf
doi  openurl
  Title Influence of fiber connectivity in simulations of cardiac biomechanics Type Journal Article
  Year 2019 Publication International Journal of Computer Assisted Radiology and Surgery Abbreviated Journal IJCAR  
  Volume 14 Issue 1 Pages (down) 63–72  
  Keywords Cardiac electromechanical simulations; Diffusion tensor imaging; Fiber connectivity  
  Abstract PURPOSE:
Personalized computational simulations of the heart could open up new improved approaches to diagnosis and surgery assistance systems. While it is fully recognized that myocardial fiber orientation is central for the construction of realistic computational models of cardiac electromechanics, the role of its overall architecture and connectivity remains unclear. Morphological studies show that the distribution of cardiac muscular fibers at the basal ring connects epicardium and endocardium. However, computational models simplify their distribution and disregard the basal loop. This work explores the influence in computational simulations of fiber distribution at different short-axis cuts.

METHODS:
We have used a highly parallelized computational solver to test different fiber models of ventricular muscular connectivity. We have considered two rule-based mathematical models and an own-designed method preserving basal connectivity as observed in experimental data. Simulated cardiac functional scores (rotation, torsion and longitudinal shortening) were compared to experimental healthy ranges using generalized models (rotation) and Mahalanobis distances (shortening, torsion).

RESULTS:
The probability of rotation was significantly lower for ruled-based models [95% CI (0.13, 0.20)] in comparison with experimental data [95% CI (0.23, 0.31)]. The Mahalanobis distance for experimental data was in the edge of the region enclosing 99% of the healthy population.

CONCLUSIONS:
Cardiac electromechanical simulations of the heart with fibers extracted from experimental data produce functional scores closer to healthy ranges than rule-based models disregarding architecture connectivity.
 
  Address  
  Corporate Author Thesis  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 601.323; 600.139; 600.145 Approved no  
  Call Number Admin @ si @ GAB2019a Serial 3133  
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Author Carles Sanchez; Debora Gil; Jorge Bernal; F. Javier Sanchez; Marta Diez-Ferrer; Antoni Rosell edit   pdf
openurl 
  Title Navigation Path Retrieval from Videobronchoscopy using Bronchial Branches Type Conference Article
  Year 2016 Publication 19th International Conference on Medical Image Computing and Computer Assisted Intervention Workshops Abbreviated Journal  
  Volume 9401 Issue Pages (down) 62-70  
  Keywords Bronchoscopy navigation; Lumen center; Brochial branches; Navigation path; Videobronchoscopy  
  Abstract Bronchoscopy biopsy can be used to diagnose lung cancer without risking complications of other interventions like transthoracic needle aspiration. During bronchoscopy, the clinician has to navigate through the bronchial tree to the target lesion. A main drawback is the difficulty to check whether the exploration is following the correct path. The usual guidance using fluoroscopy implies repeated radiation of the clinician, while alternative systems (like electromagnetic navigation) require specific equipment that increases intervention costs. We propose to compute the navigated path using anatomical landmarks extracted from the sole analysis of videobronchoscopy images. Such landmarks allow matching the current exploration to the path previously planned on a CT to indicate clinician whether the planning is being correctly followed or not. We present a feasibility study of our landmark based CT-video matching using bronchoscopic videos simulated on a virtual bronchoscopy interactive interface.  
  Address Quebec; Canada; September 2016  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference MICCAIW  
  Notes IAM; MV; 600.060; 600.075 Approved no  
  Call Number Admin @ si @ SGB2016 Serial 2885  
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Author Jaume Garcia; Debora Gil; Francesc Carreras; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados edit   pdf
url  openurl
  Title Patrons de Normalitat Regional per la Valoració de la Funció del Ventricle Esquerre Type Conference Article
  Year 2008 Publication XX Congrés de la Societat Catalana de Cardiologia Abbreviated Journal  
  Volume Issue Pages (down) 60  
  Keywords  
  Abstract Les malalties cardiovasculars afecten les propietats contràctils de la banda ventricular i provoquen una variació de la funció del Ventricle Esquerre (VE) . Només els indicadors locals (strains, la deformació del teixit) són capaços de detectar anomalies en territoris específics del VE . Patrons de normalitat regionals d’aquests paràmetres serien d’utilitat a l’hora de valorar-ne la funció .
Presentem un Domini Paramètric Normalitzat (DPN) que permet comparar dades de diferents pacients i definir Patrons de Normalitat Regional (PNR)
 
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona Editor  
  Language catalan Summary Language catalan Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ GGC2008b Serial 1503  
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