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Author David Roche; Debora Gil; Jesus Giraldo edit  doi
openurl 
  Title Mechanistic analysis of the function of agonists and allosteric modulators: Reconciling two-state and operational models Type Journal Article
  Year 2013 Publication British Journal of Pharmacology Abbreviated Journal BJP  
  Volume 169 Issue 6 Pages 1189-202  
  Keywords  
  Abstract Two-state and operational models of both agonism and allosterism are compared to identify and characterize common pharmacological parameters. To account for the receptor-dependent basal response, constitutive receptor activity is considered in the operational models. By arranging two-state models as the fraction of active receptors and operational models as the fractional response relative to the maximum effect of the system, a one-by-one correspondence between parameters is found. The comparative analysis allows a better understanding of complex allosteric interactions. In particular, the inclusion of constitutive receptor activity in the operational model of allosterism allows the characterization of modulators able to lower the basal response of the system; that is, allosteric modulators with negative intrinsic efficacy. Theoretical simulations and overall goodness of fit of the models to simulated data suggest that it is feasible to apply the models to experimental data and constitute one step forward in receptor theory formalism.  
  Address  
  Corporate Author Thesis (down)  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.044; 605.203 Approved no  
  Call Number IAM @ iam @ RGG2013b Serial 2195  
Permanent link to this record
 

 
Author Joan M. Nuñez; Debora Gil; Fernando Vilariño edit  doi
openurl 
  Title Finger joint characterization from X-ray images for rheymatoid arthritis assessment Type Conference Article
  Year 2013 Publication 6th International Conference on Biomedical Electronics and Devices Abbreviated Journal  
  Volume Issue Pages 288-292  
  Keywords Rheumatoid Arthritis; X-Ray; Hand Joint; Sclerosis; Sharp Van der Heijde  
  Abstract In this study we propose amodular systemfor automatic rheumatoid arthritis assessment which provides a joint space width measure. A hand joint model is proposed based on the accurate analysis of a X-ray finger joint image sample set. This model shows that the sclerosis and the lower bone are the main necessary features in order to perform a proper finger joint characterization. We propose sclerosis and lower bone detection methods as well as the experimental setup necessary for its performance assessment. Our characterization is used to propose and compute a joint space width score which is shown to be related to the different degrees of arthritis. This assertion is verified by comparing our proposed score with Sharp Van der Heijde score, confirming that the lower our score is the more advanced is the patient affection.  
  Address Barcelona; February 2013  
  Corporate Author Thesis (down)  
  Publisher SciTePress Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area 800 Expedition Conference BIODEVICES  
  Notes IAM;MV; 600.057; 600.054;SIAI Approved no  
  Call Number IAM @ iam @ NGV2013 Serial 2196  
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Author David Roche; Debora Gil; Jesus Giraldo edit  doi
isbn  openurl
  Title Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? Type Book Chapter
  Year 2014 Publication G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology Abbreviated Journal  
  Volume 796 Issue 3 Pages 159-181  
  Keywords β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model  
  Abstract Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.  
  Address  
  Corporate Author Thesis (down)  
  Publisher Springer Netherlands Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0065-2598 ISBN 978-94-007-7422-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number IAM @ iam @ RGG2014 Serial 2197  
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Author Joan M. Nuñez; Jorge Bernal; F. Javier Sanchez; Fernando Vilariño edit   pdf
doi  openurl
  Title Blood Vessel Characterization in Colonoscopy Images to Improve Polyp Localization Type Conference Article
  Year 2013 Publication Proceedings of the International Conference on Computer Vision Theory and Applications Abbreviated Journal  
  Volume 1 Issue Pages 162-171  
  Keywords Colonoscopy; Blood vessel; Linear features; Valley detection  
  Abstract This paper presents an approach to mitigate the contribution of blood vessels to the energy image used at different tasks of automatic colonoscopy image analysis. This goal is achieved by introducing a characterization of endoluminal scene objects which allows us to differentiate between the trace of 2-dimensional visual objects,such as vessels, and shades from 3-dimensional visual objects, such as folds. The proposed characterization is based on the influence that the object shape has in the resulting visual feature, and it leads to the development of a blood vessel attenuation algorithm. A database consisting of manually labelled masks was built in order to test the performance of our method, which shows an encouraging success in blood vessel mitigation while keeping other structures intact. Moreover, by extending our method to the only available polyp localization
algorithm tested on a public database, blood vessel mitigation proved to have a positive influence on the overall performance.
 
  Address Barcelona; February 2013  
  Corporate Author Thesis (down)  
  Publisher SciTePress Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area 800 Expedition Conference VISIGRAPP  
  Notes MV; 600.054; 600.057;SIAI Approved no  
  Call Number IAM @ iam @ NBS2013 Serial 2198  
Permanent link to this record
 

 
Author Angel Sappa; Jordi Vitria edit  doi
isbn  openurl
  Title Multimodal Interaction in Image and Video Applications Type Book Whole
  Year 2013 Publication Multimodal Interaction in Image and Video Applications Abbreviated Journal  
  Volume 48 Issue Pages  
  Keywords  
  Abstract Book Series Intelligent Systems Reference Library  
  Address  
  Corporate Author Thesis (down)  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1868-4394 ISBN 978-3-642-35931-6 Medium  
  Area Expedition Conference  
  Notes ADAS; OR;MV Approved no  
  Call Number Admin @ si @ SaV2013 Serial 2199  
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Author David Fernandez; Josep Llados; Alicia Fornes; R.Manmatha edit   pdf
doi  isbn
openurl 
  Title On Influence of Line Segmentation in Efficient Word Segmentation in Old Manuscripts Type Conference Article
  Year 2012 Publication 13th International Conference on Frontiers in Handwriting Recognition Abbreviated Journal  
  Volume Issue Pages 763-768  
  Keywords document image processing;handwritten character recognition;history;image segmentation;Spanish document;historical document;line segmentation;old handwritten document;old manuscript;word segmentation;Bifurcation;Dynamic programming;Handwriting recognition;Image segmentation;Measurement;Noise;Skeleton;Segmentation;document analysis;document and text processing;handwriting analysis;heuristics;path-finding  
  Abstract he objective of this work is to show the importance of a good line segmentation to obtain better results in the segmentation of words of historical documents. We have used the approach developed by Manmatha and Rothfeder [1] to segment words in old handwritten documents. In their work the lines of the documents are extracted using projections. In this work, we have developed an approach to segment lines more efficiently. The new line segmentation algorithm tackles with skewed, touching and noisy lines, so it is significantly improves word segmentation. Experiments using Spanish documents from the Marriages Database of the Barcelona Cathedral show that this approach reduces the error rate by more than 20%  
  Address  
  Corporate Author Thesis (down)  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-1-4673-2262-1 Medium  
  Area Expedition Conference ICFHR  
  Notes DAG Approved no  
  Call Number Admin @ si @ FLF2012 Serial 2200  
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Author Javier Marin; David Vazquez; Antonio Lopez; Jaume Amores; Ludmila I. Kuncheva edit   pdf
url  doi
openurl 
  Title Occlusion handling via random subspace classifiers for human detection Type Journal Article
  Year 2014 Publication IEEE Transactions on Systems, Man, and Cybernetics (Part B) Abbreviated Journal TSMCB  
  Volume 44 Issue 3 Pages 342-354  
  Keywords Pedestriand Detection; occlusion handling  
  Abstract This paper describes a general method to address partial occlusions for human detection in still images. The Random Subspace Method (RSM) is chosen for building a classifier ensemble robust against partial occlusions. The component classifiers are chosen on the basis of their individual and combined performance. The main contribution of this work lies in our approach’s capability to improve the detection rate when partial occlusions are present without compromising the detection performance on non occluded data. In contrast to many recent approaches, we propose a method which does not require manual labelling of body parts, defining any semantic spatial components, or using additional data coming from motion or stereo. Moreover, the method can be easily extended to other object classes. The experiments are performed on three large datasets: the INRIA person dataset, the Daimler Multicue dataset, and a new challenging dataset, called PobleSec, in which a considerable number of targets are partially occluded. The different approaches are evaluated at the classification and detection levels for both partially occluded and non-occluded data. The experimental results show that our detector outperforms state-of-the-art approaches in the presence of partial occlusions, while offering performance and reliability similar to those of the holistic approach on non-occluded data. The datasets used in our experiments have been made publicly available for benchmarking purposes  
  Address  
  Corporate Author Thesis (down)  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2168-2267 ISBN Medium  
  Area Expedition Conference  
  Notes ADAS; 605.203; 600.057; 600.054; 601.042; 601.187; 600.076 Approved no  
  Call Number ADAS @ adas @ MVL2014 Serial 2213  
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Author Jiaolong Xu; David Vazquez; Antonio Lopez; Javier Marin; Daniel Ponsa edit   pdf
doi  isbn
openurl 
  Title Learning a Multiview Part-based Model in Virtual World for Pedestrian Detection Type Conference Article
  Year 2013 Publication IEEE Intelligent Vehicles Symposium Abbreviated Journal  
  Volume Issue Pages 467 - 472  
  Keywords Pedestrian Detection; Virtual World; Part based  
  Abstract State-of-the-art deformable part-based models based on latent SVM have shown excellent results on human detection. In this paper, we propose to train a multiview deformable part-based model with automatically generated part examples from virtual-world data. The method is efficient as: (i) the part detectors are trained with precisely extracted virtual examples, thus no latent learning is needed, (ii) the multiview pedestrian detector enhances the performance of the pedestrian root model, (iii) a top-down approach is used for part detection which reduces the searching space. We evaluate our model on Daimler and Karlsruhe Pedestrian Benchmarks with publicly available Caltech pedestrian detection evaluation framework and the result outperforms the state-of-the-art latent SVM V4.0, on both average miss rate and speed (our detector is ten times faster).  
  Address Gold Coast; Australia; June 2013  
  Corporate Author Thesis (down)  
  Publisher IEEE Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1931-0587 ISBN 978-1-4673-2754-1 Medium  
  Area Expedition Conference IV  
  Notes ADAS; 600.054; 600.057 Approved no  
  Call Number XVL2013; ADAS @ adas @ xvl2013a Serial 2214  
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Author Juan Ramon Terven Salinas; Joaquin Salas; Bogdan Raducanu edit   pdf
openurl 
  Title Estado del Arte en Sistemas de Vision Artificial para Personas Invidentes Type Journal
  Year 2013 Publication Komputer Sapiens Abbreviated Journal KS  
  Volume 1 Issue Pages 20-25  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis (down)  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes OR;MV Approved no  
  Call Number Admin @ si @ TSR2013 Serial 2231  
Permanent link to this record
 

 
Author Patricia Marquez; Debora Gil; Aura Hernandez-Sabate; Daniel Kondermann edit   pdf
url  doi
isbn  openurl
  Title When Is A Confidence Measure Good Enough? Type Conference Article
  Year 2013 Publication 9th International Conference on Computer Vision Systems Abbreviated Journal  
  Volume 7963 Issue Pages 344-353  
  Keywords Optical flow, confidence measure, performance evaluation  
  Abstract Confidence estimation has recently become a hot topic in image processing and computer vision.Yet, several definitions exist of the term “confidence” which are sometimes used interchangeably. This is a position paper, in which we aim to give an overview on existing definitions,
thereby clarifying the meaning of the used terms to facilitate further research in this field. Based on these clarifications, we develop a theory to compare confidence measures with respect to their quality.
 
  Address St Petersburg; Russia; July 2013  
  Corporate Author Thesis (down)  
  Publisher Springer Link Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-39401-0 Medium  
  Area Expedition Conference ICVS  
  Notes IAM;ADAS; 600.044; 600.057; 600.060; 601.145 Approved no  
  Call Number IAM @ iam @ MGH2013a Serial 2218  
Permanent link to this record
 

 
Author David Vazquez; Jiaolong Xu; Sebastian Ramos; Antonio Lopez; Daniel Ponsa edit   pdf
doi  openurl
  Title Weakly Supervised Automatic Annotation of Pedestrian Bounding Boxes Type Conference Article
  Year 2013 Publication CVPR Workshop on Ground Truth – What is a good dataset? Abbreviated Journal  
  Volume Issue Pages 706 - 711  
  Keywords Pedestrian Detection; Domain Adaptation  
  Abstract Among the components of a pedestrian detector, its trained pedestrian classifier is crucial for achieving the desired performance. The initial task of the training process consists in collecting samples of pedestrians and background, which involves tiresome manual annotation of pedestrian bounding boxes (BBs). Thus, recent works have assessed the use of automatically collected samples from photo-realistic virtual worlds. However, learning from virtual-world samples and testing in real-world images may suffer the dataset shift problem. Accordingly, in this paper we assess an strategy to collect samples from the real world and retrain with them, thus avoiding the dataset shift, but in such a way that no BBs of real-world pedestrians have to be provided. In particular, we train a pedestrian classifier based on virtual-world samples (no human annotation required). Then, using such a classifier we collect pedestrian samples from real-world images by detection. After, a human oracle rejects the false detections efficiently (weak annotation). Finally, a new classifier is trained with the accepted detections. We show that this classifier is competitive with respect to the counterpart trained with samples collected by manually annotating hundreds of pedestrian BBs.  
  Address Portland; Oregon; June 2013  
  Corporate Author Thesis (down)  
  Publisher IEEE Place of Publication Editor  
  Language English Summary Language English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CVPRW  
  Notes ADAS; 600.054; 600.057; 601.217 Approved no  
  Call Number ADAS @ adas @ VXR2013a Serial 2219  
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Author Jiaolong Xu; David Vazquez; Sebastian Ramos; Antonio Lopez; Daniel Ponsa edit   pdf
doi  openurl
  Title Adapting a Pedestrian Detector by Boosting LDA Exemplar Classifiers Type Conference Article
  Year 2013 Publication CVPR Workshop on Ground Truth – What is a good dataset? Abbreviated Journal  
  Volume Issue Pages 688 - 693  
  Keywords Pedestrian Detection; Domain Adaptation  
  Abstract Training vision-based pedestrian detectors using synthetic datasets (virtual world) is a useful technique to collect automatically the training examples with their pixel-wise ground truth. However, as it is often the case, these detectors must operate in real-world images, experiencing a significant drop of their performance. In fact, this effect also occurs among different real-world datasets, i.e. detectors' accuracy drops when the training data (source domain) and the application scenario (target domain) have inherent differences. Therefore, in order to avoid this problem, it is required to adapt the detector trained with synthetic data to operate in the real-world scenario. In this paper, we propose a domain adaptation approach based on boosting LDA exemplar classifiers from both virtual and real worlds. We evaluate our proposal on multiple real-world pedestrian detection datasets. The results show that our method can efficiently adapt the exemplar classifiers from virtual to real world, avoiding drops in average precision over the 15%.  
  Address Portland; oregon; June 2013  
  Corporate Author Thesis (down)  
  Publisher Place of Publication Editor  
  Language English Summary Language English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CVPRW  
  Notes ADAS; 600.054; 600.057; 601.217 Approved yes  
  Call Number XVR2013; ADAS @ adas @ xvr2013a Serial 2220  
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Author Thierry Brouard; Jordi Gonzalez; Caifeng Shan; Massimo Piccardi; Larry S. Davis edit   pdf
doi  openurl
  Title Special issue on background modeling for foreground detection in real-world dynamic scenes Type Journal Article
  Year 2014 Publication Machine Vision and Applications Abbreviated Journal MVAP  
  Volume 25 Issue 5 Pages 1101-1103  
  Keywords  
  Abstract Although background modeling and foreground detection are not mandatory steps for computer vision applications, they may prove useful as they separate the primal objects usually called “foreground” from the remaining part of the scene called “background”, and permits different algorithmic treatment in the video processing field such as video surveillance, optical motion capture, multimedia applications, teleconferencing and human–computer interfaces. Conventional background modeling methods exploit the temporal variation of each pixel to model the background, and the foreground detection is made using change detection. The last decade witnessed very significant publications on background modeling but recently new applications in which background is not static, such as recordings taken from mobile devices or Internet videos, need new developments to detect robustly moving objects in challenging environments. Thus, effective methods for robustness to deal both with dynamic backgrounds, i  
  Address  
  Corporate Author Thesis (down)  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0932-8092 ISBN Medium  
  Area Expedition Conference  
  Notes ISE; 600.078 Approved no  
  Call Number BGS2014a Serial 2411  
Permanent link to this record
 

 
Author Joan Mas; Gemma Sanchez; Josep Llados edit  doi
isbn  openurl
  Title SSP: Sketching slide Presentations, a Syntactic Approach Type Book Chapter
  Year 2010 Publication Graphics Recognition. Achievements, Challenges, and Evolution. 8th International Workshop, GREC 2009. Selected Papers Abbreviated Journal  
  Volume 6020 Issue Pages 118-129  
  Keywords  
  Abstract The design of a slide presentation is a creative process. In this process first, humans visualize in their minds what they want to explain. Then, they have to be able to represent this knowledge in an understandable way. There exists a lot of commercial software that allows to create our own slide presentations but the creativity of the user is rather limited. In this article we present an application that allows the user to create and visualize a slide presentation from a sketch. A slide may be seen as a graphical document or a diagram where its elements are placed in a particular spatial arrangement. To describe and recognize slides a syntactic approach is proposed. This approach is based on an Adjacency Grammar and a parsing methodology to cope with this kind of grammars. The experimental evaluation shows the performance of our methodology from a qualitative and a quantitative point of view. Six different slides containing different number of symbols, from 4 to 7, have been given to the users and they have drawn them without restrictions in the order of the elements. The quantitative results give an idea on how suitable is our methodology to describe and recognize the different elements in a slide.  
  Address  
  Corporate Author Thesis (down)  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-13727-3 Medium  
  Area Expedition Conference GREC  
  Notes DAG Approved no  
  Call Number MSL2010 Serial 2405  
Permanent link to this record
 

 
Author Mathieu Nicolas Delalandre; Jean-Yves Ramel; Ernest Valveny; Muhammad Muzzamil Luqman edit  doi
isbn  openurl
  Title A Performance Characterization Algorithm for Symbol Localization Type Book Chapter
  Year 2010 Publication Graphics Recognition. Achievements, Challenges, and Evolution. 8th International Workshop, GREC 2009. Selected Papers Abbreviated Journal  
  Volume 6020 Issue Pages 260–271  
  Keywords  
  Abstract In this paper we present an algorithm for performance characterization of symbol localization systems. This algorithm is aimed to be a more “reliable” and “open” solution to characterize the performance. To achieve that, it exploits only single points as the result of localization and offers the possibility to reconsider the localization results provided by a system. We use the information about context in groundtruth, and overall localization results, to detect the ambiguous localization results. A probability score is computed for each matching between a localization point and a groundtruth region, depending on the spatial distribution of the other regions in the groundtruth. Final characterization is given with detection rate/probability score plots, describing the sets of possible interpretations of the localization results, according to a given confidence rate. We present experimentation details along with the results for the symbol localization system of [1], exploiting a synthetic dataset of architectural floorplans and electrical diagrams (composed of 200 images and 3861 symbols).  
  Address  
  Corporate Author Thesis (down)  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-13727-3 Medium  
  Area Expedition Conference GREC  
  Notes DAG Approved no  
  Call Number Admin @ si @ DRV2010 Serial 2406  
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