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Simone Balocco, O. Camara, E. Vivas, T. Sola, L. Guimaraens, H. A. van Andel, et al. (2010). Feasibility of Estimating Regional Mechanical Properties of Cerebral Aneurysms In Vivo. MEDPHYS - Medical Physics, 37(4), 1689–1706.
Abstract: PURPOSE:
In this article, the authors studied the feasibility of estimating regional mechanical properties in cerebral aneurysms, integrating information extracted from imaging and physiological data with generic computational models of the arterial wall behavior.
METHODS:
A data assimilation framework was developed to incorporate patient-specific geometries into a given biomechanical model, whereas wall motion estimates were obtained from applying registration techniques to a pair of simulated MR images and guided the mechanical parameter estimation. A simple incompressible linear and isotropic Hookean model coupled with computational fluid-dynamics was employed as a first approximation for computational purposes. Additionally, an automatic clustering technique was developed to reduce the number of parameters to assimilate at the optimization stage and it considerably accelerated the convergence of the simulations. Several in silico experiments were designed to assess the influence of aneurysm geometrical characteristics and the accuracy of wall motion estimates on the mechanical property estimates. Hence, the proposed methodology was applied to six real cerebral aneurysms and tested against a varying number of regions with different elasticity, different mesh discretization, imaging resolution, and registration configurations.
RESULTS:
Several in silico experiments were conducted to investigate the feasibility of the proposed workflow, results found suggesting that the estimation of the mechanical properties was mainly influenced by the image spatial resolution and the chosen registration configuration. According to the in silico experiments, the minimal spatial resolution needed to extract wall pulsation measurements with enough accuracy to guide the proposed data assimilation framework was of 0.1 mm.
CONCLUSIONS:
Current routine imaging modalities do not have such a high spatial resolution and therefore the proposed data assimilation framework cannot currently be used on in vivo data to reliably estimate regional properties in cerebral aneurysms. Besides, it was observed that the incorporation of fluid-structure interaction in a biomechanical model with linear and isotropic material properties did not have a substantial influence in the final results.
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Carles Sanchez, Jorge Bernal, F. Javier Sanchez, Marta Diez-Ferrer, Antoni Rosell, & Debora Gil. (2015). Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy. In 6th International Conference on Information Processing in Computer-Assisted Interventions IPCAI2015 (Vol. 10, pp. 935–945).
Abstract: PURPOSE:
Lack of objective measurement of tracheal obstruction degree has a negative impact on the chosen treatment prone to lead to unnecessary repeated explorations and other scanners. Accurate computation of tracheal stenosis in videobronchoscopy would constitute a breakthrough for this noninvasive technique and a reduction in operation cost for the public health service.
METHODS:
Stenosis calculation is based on the comparison of the region delimited by the lumen in an obstructed frame and the region delimited by the first visible ring in a healthy frame. We propose a parametric strategy for the extraction of lumen and tracheal ring regions based on models of their geometry and appearance that guide a deformable model. To ensure a systematic applicability, we present a statistical framework to choose optimal parametric values and a strategy to choose the frames that minimize the impact of scope optical distortion.
RESULTS:
Our method has been tested in 40 cases covering different stenosed tracheas. Experiments report a non- clinically relevant [Formula: see text] of discrepancy in the calculated stenotic area and a computational time allowing online implementation in the operating room.
CONCLUSIONS:
Our methodology allows reliable measurements of airway narrowing in the operating room. To fully assess its clinical impact, a prospective clinical trial should be done.
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Debora Gil, Ruth Aris, Agnes Borras, Esmitt Ramirez, Rafael Sebastian, & Mariano Vazquez. (2019). Influence of fiber connectivity in simulations of cardiac biomechanics. IJCAR - International Journal of Computer Assisted Radiology and Surgery, 14(1), 63–72.
Abstract: PURPOSE:
Personalized computational simulations of the heart could open up new improved approaches to diagnosis and surgery assistance systems. While it is fully recognized that myocardial fiber orientation is central for the construction of realistic computational models of cardiac electromechanics, the role of its overall architecture and connectivity remains unclear. Morphological studies show that the distribution of cardiac muscular fibers at the basal ring connects epicardium and endocardium. However, computational models simplify their distribution and disregard the basal loop. This work explores the influence in computational simulations of fiber distribution at different short-axis cuts.
METHODS:
We have used a highly parallelized computational solver to test different fiber models of ventricular muscular connectivity. We have considered two rule-based mathematical models and an own-designed method preserving basal connectivity as observed in experimental data. Simulated cardiac functional scores (rotation, torsion and longitudinal shortening) were compared to experimental healthy ranges using generalized models (rotation) and Mahalanobis distances (shortening, torsion).
RESULTS:
The probability of rotation was significantly lower for ruled-based models [95% CI (0.13, 0.20)] in comparison with experimental data [95% CI (0.23, 0.31)]. The Mahalanobis distance for experimental data was in the edge of the region enclosing 99% of the healthy population.
CONCLUSIONS:
Cardiac electromechanical simulations of the heart with fibers extracted from experimental data produce functional scores closer to healthy ranges than rule-based models disregarding architecture connectivity.
Keywords: Cardiac electromechanical simulations; Diffusion tensor imaging; Fiber connectivity
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Francesco Ciompi, Simone Balocco, Juan Rigla, Xavier Carrillo, Josefina Mauri, & Petia Radeva. (2016). Computer-Aided Detection of Intra-Coronary Stent in Intravascular Ultrasound Sequences. MP - Medical Physics, 43(10).
Abstract: Purpose: An intraluminal coronary stent is a metal mesh tube deployed in a stenotic artery during Percutaneous Coronary Intervention (PCI), in order to prevent acute vessel occlusion. The identication of struts location and the denition of the stent shape are relevant for PCI planning 15 and for patient follow-up. We present a fully-automatic framework for Computer-Aided Detection
(CAD) of intra-coronary stents in Intravascular Ultrasound (IVUS) image sequences. The CAD system is able to detect stent struts and estimate the stent shape.
Methods: The proposed CAD uses machine learning to provide a comprehensive interpretation of the local structure of the vessel by means of semantic classication. The output of the classication 20 stage is then used to detect struts and to estimate the stent shape. The proposed approach is validated using a multi-centric data-set of 1,015 images from 107 IVUS sequences containing both metallic and bio-absorbable stents.
Results: The method was able to detect structs in both metallic stents with an overall F-measure of 77.7% and a mean distance of 0.15 mm from manually annotated struts, and in bio-absorbable 25 stents with an overall F-measure of 77.4% and a mean distance of 0.09 mm from manually annotated struts.
Conclusions: The results are close to the inter-observer variability and suggest that the system has the potential of being used as method for aiding percutaneous interventions.
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Jordi Gonzalez, Thomas B. Moeslund, & Liang Wang. (2012). Semantic Understanding of Human Behaviors in Image Sequences: From video-surveillance to video-hermeneutics. CVIU - Computer Vision and Image Understanding, 116(3), 305–306.
Abstract: Purpose: Atheromatic plaque progression is affected, among others phenomena, by biomechanical, biochemical, and physiological factors. In this paper, the authors introduce a novel framework able to provide both morphological (vessel radius, plaque thickness, and type) and biomechanical (wall shear stress and Von Mises stress) indices of coronary arteries.Methods: First, the approach reconstructs the three-dimensional morphology of the vessel from intravascular ultrasound (IVUS) and Angiographic sequences, requiring minimal user interaction. Then, a computational pipeline allows to automatically assess fluid-dynamic and mechanical indices. Ten coronary arteries are analyzed illustrating the capabilities of the tool and confirming previous technical and clinical observations.Results: The relations between the arterial indices obtained by IVUS measurement and simulations have been quantitatively analyzed along the whole surface of the artery, extending the analysis of the coronary arteries shown in previous state of the art studies. Additionally, for the first time in the literature, the framework allows the computation of the membrane stresses using a simplified mechanical model of the arterial wall.Conclusions: Circumferentially (within a given frame), statistical analysis shows an inverse relation between the wall shear stress and the plaque thickness. At the global level (comparing a frame within the entire vessel), it is observed that heavy plaque accumulations are in general calcified and are located in the areas of the vessel having high wall shear stress. Finally, in their experiments the inverse proportionality between fluid and structural stresses is observed.
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Fahad Shahbaz Khan. (2011). Coloring bag-of-words based image representations (Joost Van de Weijer, & Maria Vanrell, Eds.). Ph.D. thesis, , .
Abstract: Put succinctly, the bag-of-words based image representation is the most successful approach for object and scene recognition. Within the bag-of-words framework the optimal fusion of multiple cues, such as shape, texture and color, still remains an active research domain. There exist two main approaches to combine color and shape information within the bag-of-words framework. The first approach called, early fusion, fuses color and shape at the feature level as a result of which a joint colorshape vocabulary is produced. The second approach, called late fusion, concatenates histogram representation of both color and shape, obtained independently. In the first part of this thesis, we analyze the theoretical implications of both early and late feature fusion. We demonstrate that both these approaches are suboptimal for a subset of object categories. Consequently, we propose a novel method for recognizing object categories when using multiple cues by separately processing the shape and color cues and combining them by modulating the shape features by category specific color attention. Color is used to compute bottom-up and top-down attention maps. Subsequently, the color attention maps are used to modulate the weights of the shape features. Shape features are given more weight in regions with higher attention and vice versa. The approach is tested on several benchmark object recognition data sets and the results clearly demonstrate the effectiveness of our proposed method. In the second part of the thesis, we investigate the problem of obtaining compact spatial pyramid representations for object and scene recognition. Spatial pyramids have been successfully applied to incorporate spatial information into bag-of-words based image representation. However, a major drawback of spatial pyramids is that it leads to high dimensional image representations. We present a novel framework for obtaining compact pyramid representation. The approach reduces the size of a high dimensional pyramid representation upto an order of magnitude without any significant reduction in accuracy. Moreover, we also investigate the optimal combination of multiple features such as color and shape within the context of our compact pyramid representation. Finally, we describe a novel technique to build discriminative visual words from multiple cues learned independently from training images. To this end, we use an information theoretic vocabulary compression technique to find discriminative combinations of visual cues and the resulting visual vocabulary is compact, has the cue binding property, and supports individual weighting of cues in the final image representation. The approach is tested on standard object recognition data sets. The results obtained clearly demonstrate the effectiveness of our approach.
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Clementine Decamps, Alexis Arnaud, Florent Petitprez, Mira Ayadi, Aurelia Baures, Lucile Armenoult, et al. (2021). DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification. BMC Bioinformatics, 22, 473.
Abstract: Quantification of tumor heterogeneity is essential to better understand cancer progression and to adapt therapeutic treatments to patient specificities. Bioinformatic tools to assess the different cell populations from single-omic datasets as bulk transcriptome or methylome samples have been recently developed, including reference-based and reference-free methods. Improved methods using multi-omic datasets are yet to be developed in the future and the community would need systematic tools to perform a comparative evaluation of these algorithms on controlled data.
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Tadashi Araki, Sumit K. Banchhor, Narendra D. Londhe, Nobutaka Ikeda, Petia Radeva, Devarshi Shukla, et al. (2016). Reliable and Accurate Calcium Volume Measurement in Coronary Artery Using Intravascular Ultrasound Videos. JMS - Journal of Medical Systems, 40(3), 51:1–51:20.
Abstract: Quantitative assessment of calcified atherosclerotic volume within the coronary artery wall is vital for cardiac interventional procedures. The goal of this study is to automatically measure the calcium volume, given the borders of coronary vessel wall for all the frames of the intravascular ultrasound (IVUS) video. Three soft computing fuzzy classification techniques were adapted namely Fuzzy c-Means (FCM), K-means, and Hidden Markov Random Field (HMRF) for automated segmentation of calcium regions and volume computation. These methods were benchmarked against previously developed threshold-based method. IVUS image data sets (around 30,600 IVUS frames) from 15 patients were collected using 40 MHz IVUS catheter (Atlantis® SR Pro, Boston Scientific®, pullback speed of 0.5 mm/s). Calcium mean volume for FCM, K-means, HMRF and threshold-based method were 37.84 ± 17.38 mm3, 27.79 ± 10.94 mm3, 46.44 ± 19.13 mm3 and 35.92 ± 16.44 mm3 respectively. Cross-correlation, Jaccard Index and Dice Similarity were highest between FCM and threshold-based method: 0.99, 0.92 ± 0.02 and 0.95 + 0.02 respectively. Student’s t-test, z-test and Wilcoxon-test are also performed to demonstrate consistency, reliability and accuracy of the results. Given the vessel wall region, the system reliably and automatically measures the calcium volume in IVUS videos. Further, we validated our system against a trained expert using scoring: K-means showed the best performance with an accuracy of 92.80 %. Out procedure and protocol is along the line with method previously published clinically.
Keywords: Interventional cardiology; Atherosclerosis; Coronary arteries; IVUS; calcium volume; Soft computing; Performance Reliability; Accuracy
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Victor M. Campello, Carlos Martin-Isla, Cristian Izquierdo, Andrea Guala, Jose F. Rodriguez Palomares, David Vilades, et al. (2022). Minimising multi-centre radiomics variability through image normalisation: a pilot study. ScR - Scientific Reports, 12(1), 12532.
Abstract: Radiomics is an emerging technique for the quantification of imaging data that has recently shown great promise for deeper phenotyping of cardiovascular disease. Thus far, the technique has been mostly applied in single-centre studies. However, one of the main difficulties in multi-centre imaging studies is the inherent variability of image characteristics due to centre differences. In this paper, a comprehensive analysis of radiomics variability under several image- and feature-based normalisation techniques was conducted using a multi-centre cardiovascular magnetic resonance dataset. 218 subjects divided into healthy (n = 112) and hypertrophic cardiomyopathy (n = 106, HCM) groups from five different centres were considered. First and second order texture radiomic features were extracted from three regions of interest, namely the left and right ventricular cavities and the left ventricular myocardium. Two methods were used to assess features’ variability. First, feature distributions were compared across centres to obtain a distribution similarity index. Second, two classification tasks were proposed to assess: (1) the amount of centre-related information encoded in normalised features (centre identification) and (2) the generalisation ability for a classification model when trained on these features (healthy versus HCM classification). The results showed that the feature-based harmonisation technique ComBat is able to remove the variability introduced by centre information from radiomic features, at the expense of slightly degrading classification performance. Piecewise linear histogram matching normalisation gave features with greater generalisation ability for classification ( balanced accuracy in between 0.78 ± 0.08 and 0.79 ± 0.09). Models trained with features from images without normalisation showed the worst performance overall ( balanced accuracy in between 0.45 ± 0.28 and 0.60 ± 0.22). In conclusion, centre-related information removal did not imply good generalisation ability for classification.
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Yecong Wan, Yuanshuo Cheng, Miingwen Shao, & Jordi Gonzalez. (2022). Image rain removal and illumination enhancement done in one go. KBS - Knowledge-Based Systems, 252, 109244.
Abstract: Rain removal plays an important role in the restoration of degraded images. Recently, CNN-based methods have achieved remarkable success. However, these approaches neglect that the appearance of real-world rain is often accompanied by low light conditions, which will further degrade the image quality, thereby hindering the restoration mission. Therefore, it is very indispensable to jointly remove the rain and enhance illumination for real-world rain image restoration. To this end, we proposed a novel spatially-adaptive network, dubbed SANet, which can remove the rain and enhance illumination in one go with the guidance of degradation mask. Meanwhile, to fully utilize negative samples, a contrastive loss is proposed to preserve more natural textures and consistent illumination. In addition, we present a new synthetic dataset, named DarkRain, to boost the development of rain image restoration algorithms in practical scenarios. DarkRain not only contains different degrees of rain, but also considers different lighting conditions, and more realistically simulates real-world rainfall scenarios. SANet is extensively evaluated on the proposed dataset and attains new state-of-the-art performance against other combining methods. Moreover, after a simple transformation, our SANet surpasses existing the state-of-the-art algorithms in both rain removal and low-light image enhancement.
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Chris Bahnsen, David Vazquez, Antonio Lopez, & Thomas B. Moeslund. (2019). Learning to Remove Rain in Traffic Surveillance by Using Synthetic Data. In 14th International Conference on Computer Vision Theory and Applications (pp. 123–130).
Abstract: Rainfall is a problem in automated traffic surveillance. Rain streaks occlude the road users and degrade the overall visibility which in turn decrease object detection performance. One way of alleviating this is by artificially removing the rain from the images. This requires knowledge of corresponding rainy and rain-free images. Such images are often produced by overlaying synthetic rain on top of rain-free images. However, this method fails to incorporate the fact that rain fall in the entire three-dimensional volume of the scene. To overcome this, we introduce training data from the SYNTHIA virtual world that models rain streaks in the entirety of a scene. We train a conditional Generative Adversarial Network for rain removal and apply it on traffic surveillance images from SYNTHIA and the AAU RainSnow datasets. To measure the applicability of the rain-removed images in a traffic surveillance context, we run the YOLOv2 object detection algorithm on the original and rain-removed frames. The results on SYNTHIA show an 8% increase in detection accuracy compared to the original rain image. Interestingly, we find that high PSNR or SSIM scores do not imply good object detection performance.
Keywords: Rain Removal; Traffic Surveillance; Image Denoising
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Azadeh S. Mozafari, David Vazquez, Mansour Jamzad, & Antonio Lopez. (2016). Node-Adapt, Path-Adapt and Tree-Adapt:Model-Transfer Domain Adaptation for Random Forest.
Abstract: Random Forest (RF) is a successful paradigm for learning classifiers due to its ability to learn from large feature spaces and seamlessly integrate multi-class classification, as well as the achieved accuracy and processing efficiency. However, as many other classifiers, RF requires domain adaptation (DA) provided that there is a mismatch between the training (source) and testing (target) domains which provokes classification degradation. Consequently, different RF-DA methods have been proposed, which not only require target-domain samples but revisiting the source-domain ones, too. As novelty, we propose three inherently different methods (Node-Adapt, Path-Adapt and Tree-Adapt) that only require the learned source-domain RF and a relatively few target-domain samples for DA, i.e. source-domain samples do not need to be available. To assess the performance of our proposals we focus on image-based object detection, using the pedestrian detection problem as challenging proof-of-concept. Moreover, we use the RF with expert nodes because it is a competitive patch-based pedestrian model. We test our Node-, Path- and Tree-Adapt methods in standard benchmarks, showing that DA is largely achieved.
Keywords: Domain Adaptation; Pedestrian detection; Random Forest
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Yaxing Wang, Chenshen Wu, Luis Herranz, Joost Van de Weijer, Abel Gonzalez-Garcia, & Bogdan Raducanu. (2018). Transferring GANs: generating images from limited data. In 15th European Conference on Computer Vision (Vol. 11210, pp. 220–236). LNCS.
Abstract: ransferring knowledge of pre-trained networks to new domains by means of fine-tuning is a widely used practice for applications based on discriminative models. To the best of our knowledge this practice has not been studied within the context of generative deep networks. Therefore, we study domain adaptation applied to image generation with generative adversarial networks. We evaluate several aspects of domain adaptation, including the impact of target domain size, the relative distance between source and target domain, and the initialization of conditional GANs. Our results show that using knowledge from pre-trained networks can shorten the convergence time and can significantly improve the quality of the generated images, especially when target data is limited. We show that these conclusions can also be drawn for conditional GANs even when the pre-trained model was trained without conditioning. Our results also suggest that density is more important than diversity and a dataset with one or few densely sampled classes is a better source model than more diverse datasets such as ImageNet or Places.
Keywords: Generative adversarial networks; Transfer learning; Domain adaptation; Image generation
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Wenwen Yu, Mingyu Liu, Mingrui Chen, Ning Lu, Yinlong We, Yuliang Liu, et al. (2023). ICDAR 2023 Competition on Reading the Seal Title. In 17th International Conference on Document Analysis and Recognition (Vol. 14188, 522–535). LNCS.
Abstract: Reading seal title text is a challenging task due to the variable shapes of seals, curved text, background noise, and overlapped text. However, this important element is commonly found in official and financial scenarios, and has not received the attention it deserves in the field of OCR technology. To promote research in this area, we organized ICDAR 2023 competition on reading the seal title (ReST), which included two tasks: seal title text detection (Task 1) and end-to-end seal title recognition (Task 2). We constructed a dataset of 10,000 real seal data, covering the most common classes of seals, and labeled all seal title texts with text polygons and text contents. The competition opened on 30th December, 2022 and closed on 20th March, 2023. The competition attracted 53 participants and received 135 submissions from academia and industry, including 28 participants and 72 submissions for Task 1, and 25 participants and 63 submissions for Task 2, which demonstrated significant interest in this challenging task. In this report, we present an overview of the competition, including the organization, challenges, and results. We describe the dataset and tasks, and summarize the submissions and evaluation results. The results show that significant progress has been made in the field of seal title text reading, and we hope that this competition will inspire further research and development in this important area of OCR technology.
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Marçal Rusiñol, Lluis Gomez, A. Landman, M. Silva Constenla, & Dimosthenis Karatzas. (2019). Automatic Structured Text Reading for License Plates and Utility Meters. In BMVC Workshop on Visual Artificial Intelligence and Entrepreneurship.
Abstract: Reading text in images has attracted interest from computer vision researchers for
many years. Our technology focuses on the extraction of structured text – such as serial
numbers, machine readings, product codes, etc. – so that it is able to center its attention just on the relevant textual elements. It is conceived to work in an end-to-end fashion, bypassing any explicit text segmentation stage. In this paper we present two different industrial use cases where we have applied our automatic structured text reading technology. In the first one, we demonstrate an outstanding performance when reading license plates compared to the current state of the art. In the second one, we present results on our solution for reading utility meters. The technology is commercialized by a recently created spin-off company, and both solutions are at different stages of integration with final clients.
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