Abstract: Colorectal cancer is the fourth most common cause of cancer death worldwide and its survival rate depends on the stage in which it is detected on hence the necessity for an early colon screening. There are several screening techniques but colonoscopy is still nowadays the gold standard, although it has some drawbacks such as the miss rate. Our contribution, in the field of intelligent systems for colonoscopy, aims at providing a polyp localization and a polyp segmentation system based on a model of appearance for polyps. To develop both methods we define a model of appearance for polyps, which describes a polyp as enclosed by intensity valleys. The novelty of our contribution resides on the fact that we include in our model aspects of the image formation and we also consider the presence of other elements from the endoluminal scene such as specular highlights and blood vessels, which have an impact on the performance of our methods. In order to develop our polyp localization method we accumulate valley information in order to generate energy maps, which are also used to guide the polyp segmentation. Our methods achieve promising results in polyp localization and segmentation. As we want to explore the usability of our methods we present a comparative analysis between physicians fixations obtained via an eye tracking device and our polyp localization method. The results show that our method is indistinguishable to novice physicians although it is far from expert physicians.

Abstract: Co-segmentation is defined as jointly partitioning multiple images depicting the same or similar object, into foreground and background. Our method consists of a multiple-scale multiple-image generative model, which jointly estimates the foreground and background appearance distributions from several images, in a non-supervised manner. In contrast to other co-segmentation methods, our approach does not require the images to have similar foregrounds and different backgrounds to function properly. Region matching is applied to exploit inter-image information by establishing correspondences between the common objects that appear in the scene. Moreover, computing many-to-many associations of regions allow further applications, like recognition of object parts across images. We report results on iCoseg, a challenging dataset that presents extreme variability in camera viewpoint, illumination and object deformations and poses. We also show that our method is robust against large intra-class variability in the MSRC database.

Abstract: Cardiac magnetic resonance imaging (Cardiac MRI) has become a gold standard diagnostic technique for the assessment of cardiac mechanics, allowing the non-invasive calculation of left ventric- ular long axis longitudinal shortening (LVLS) and absolute myocardial torsion (AMT) between basal and apical left ventricular slices, a movement directly related to the helicoidal anatomic disposition of the myocardial fibers. The aim of this study is to determine AMT and LVLS behaviour and normal values from a group of healthy subjects. A group of 21 healthy volunteers (15 males) (age: 23–55 y.o., mean:30.7 ± 7.5) were prospectively included in an obser- vational study by Cardiac MRI. Left ventricular rotation (degrees) was calculated by custom-made software (Harmonic Phase Flow) in consecutive LV short axis planes tagged cine-MRI sequences. AMT was determined from the difference between basal and apical planes LV rotations. LVLS (%) was determined from the LV longitudinal and horizontal axis cine-MRI images. All the 21 cases studied were interpretable, although in three cases the value of the LV apical rotation could not be determined. The mean rotation of the basal and apical planes at end-systole were -3.71° ± 0.84° and 6.73° ± 1.69° (n:18) respectively, resulting in a LV mean AMT of 10.48° ± 1.63° (n:18). End-systolic mean LVLS was 19.07 ± 2.71%. Cardiac MRI allows for the calculation of AMT and LVLS, fundamental functional components of the ventricular twist mechanics conditioned, in turn, by the anatomical helical layout of the myocardial fibers. These values provide complementary information about systolic ventricular function in relation to the traditional parameters used in daily practice.

Abstract: Brightness induction is the modulation of the perceived intensity of an area by the luminance of surrounding areas. Although striate cortex is traditionally regarded as an area mostly responsive to ensory (i.e. retinal) information,
neurophysiological evidence suggests that perceived brightness information mightbe explicitly represented in V1.
Such evidence has been observed both in anesthetised cats where neuronal response modulations have been found to follow luminance changes outside the receptive felds and in human fMRI measurements. In this work, possible neural mechanisms that ofer a plausible explanation for such phenomenon are investigated. To this end, we consider the model proposed by Z.Li (Li, Network:Comput. Neural Syst., 10 (1999)) which is based on neurophysiological evidence and focuses on the part of V1 responsible for contextual infuences, i.e. layer 2-3 pyramidal cells, interneurons, and horizontal intracortical connections. This model has reproduced other phenomena such as contour detection and preattentive segmentation, which share with brightness induction the relevant efect of contextual infuences. We have extended the original model such that the input to the network is obtained from a complete multiscale and multiorientation wavelet decomposition, thereby allowing the recovery of an image refecting the perceived intensity. The proposed model successfully accounts for well known psychophysical efects for static contexts (among them: the White's and modifed White's efects, the Todorovic, Chevreul, achromatic ring patterns, and grating induction efects) and also for brigthness induction in dynamic contexts defned by modulating the luminance of surrounding areas (e.g. the brightness of a static central area is perceived to vary in antiphase to the sinusoidal luminance changes of its surroundings). This work thus suggests that intra-cortical interactions in V1 could partially explain perceptual brightness induction efects and reveals how a common general architecture may account for several different fundamental processes emerging early in the visual processing pathway.

Abstract: Brightness induction is the modulation of the perceived intensity of an
area by the luminance of surrounding areas. Although V1 is traditionally regarded as
an area mostly responsive to retinal information, neurophysiological evidence
suggests that it may explicitly represent brightness information. In this work, we
investigate possible neural mechanisms underlying brightness induction. To this end,
we consider the model by Z Li (1999 Computation and Neural Systems10187-212)
which is constrained by neurophysiological data and focuses on the part of V1
responsible for contextual influences. This model, which has proven to account for
phenomena such as contour detection and preattentive segmentation, shares with
brightness induction the relevant effect of contextual influences. Importantly, the
input to our network model derives from a complete multiscale and multiorientation
wavelet decomposition, which makes it possible to recover an image reflecting the
perceived luminance and successfully accounts for well known psychophysical
effects for both static and dynamic contexts. By further considering inverse problem
techniques we define induction-reversed images: given a target image, we build an
image whose perceived luminance matches the actual luminance of the original
stimulus, thus effectively canceling out brightness induction effects. We suggest that
induction-reversed images may help remove undesired perceptual effects and can
find potential applications in fields such as radiological image interpretation

Abstract: Automatic understanding of human activity and action is very important and challenging research area of Computer Vision with wide applications in video surveillance, motion analysis, virtual reality interfaces, video indexing, content based video retrieval, HCI and health care. This thesis presents a series of techniques to solve the problem of human action recognition in video. First approach towards this goal is based on a probabilistic optimization model of body parts using Hidden Markov Model. This strong model based approach is able to distinguish between similar actions by only considering the body parts having major contributions to the actions. In next approach, we apply a weak model based human detector and actions are represented by Bag-of-key poses model to capture the human pose changes during the actions. To tackle the problem of human action recognition in complex scenes, a selective spatio-temporal interest point (STIP) detector is proposed by using a mechanism similar to that of the non-classical receptive field inhibition that is exhibited by most oriented selective neuron in the primary visual cortex. An extension of the selective STIP detector is applied to multi-view action recognition system by introducing a novel 4D STIPs (3D space + time). Finally, we use our STIP detector on large scale continuous visual event recognition problem and propose a novel generalized max-margin Hough transformation framework for activity detection

Abstract: A very important aspect in manifold learning is represented by automatic estimation of the intrinsic dimensionality. Unfortunately, this problem has received few attention in the literature of manifold learning. In this paper, we argue that feature selection paradigm can be used to the problem of automatic dimensionality estimation. Besides this, it also leads to improved recognition rates. Our approach for optimal feature selection is based on a Genetic Algorithm. As a case study for manifold learning, we have considered Laplacian Eigenmaps (LE) and Locally Linear Embedding (LLE). The effectiveness of the proposed framework was tested on the face recognition problem. Extensive experiments carried out on ORL, UMIST, Yale, and Extended Yale face data sets confirmed our hypothesis.