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Debora Gil; Petia Radeva |
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Title |
A Regularized Curvature Flow Designed for a Selective Shape Restoration |
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2004 |
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IEEE Transactions on Image Processing |
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13 |
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1444–1458 |
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Geometric flows, nonlinear filtering, shape recovery. |
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Among all filtering techniques, those based exclu- sively on image level sets (geometric flows) have proven to be the less sensitive to the nature of noise and the most contrast preserving. A common feature to existent curvature flows is that they penalize high curvature, regardless of the curve regularity. This constitutes a major drawback since curvature extreme values are standard descriptors of the contour geometry. We argue that an operator designed with shape recovery purposes should include a term penalizing irregularity in the curvature rather than its magnitude. To this purpose, we present a novel geometric flow that includes a function that measures the degree of local irregularity present in the curve. A main advantage is that it achieves non-trivial steady states representing a smooth model of level curves in a noisy image. Performance of our approach is compared to classical filtering techniques in terms of quality in the restored image/shape and asymptotic behavior. We empirically prove that our approach is the technique that achieves the best compromise between image quality and evolution stabilization. |
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IAM;MILAB |
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BCNPCL @ bcnpcl @ GiR2004b |
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491 |
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Author |
Enric Marti; Debora Gil; Carme Julia |
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Una experiencia de PBL en la docencia de la asignatura de Graficos por Computador en Ingenieria Informatica |
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Miscellaneous |
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2006 |
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IV Contreso Internacional de Docencia Universitaria e Innovacion |
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1 |
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375 |
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Barcelona (Spain) |
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IAM;ADAS; |
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IAM @ iam @ MGJ2006b |
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931 |
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Author |
Debora Gil; Jaume Garcia; Mariano Vazquez; Ruth Aris; Guilleaume Houzeaux |
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Title |
Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function |
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Conference Article |
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2008 |
Publication |
8th World Congress on Computational Mechanichs (WCCM8) |
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Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance. |
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Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model. |
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Venice; Italy |
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9788496736559 |
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IAM @ iam @ GGV2008b |
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993 |
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Jaume Garcia; Debora Gil; Sandra Pujades; Francesc Carreras |
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Title |
Valoracion de la Funcion del Ventriculo Izquierdo mediante Modelos Regionales Hiperparametricos |
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2008 |
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Revista Española de Cardiologia |
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61 |
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3 |
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79 |
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La mayoría de la enfermedades cardiovasculares afectan a las propiedades contráctiles de la banda ventricular helicoidal. Esto se refleja en una variación del comportamiento normal de la función ventricular. Parámetros locales tales como los strains, o la deformación experimentada por el tejido, son indicadores capaces de detectar anomalías funcionales en territorios específicos. A menudo, dichos parámetros son considerados de forma separada. En este trabajo presentamos un marco computacional (el Dominio Paramétrico Normalizado, DPN) que permite integrarlos en hiperparámetros funcionales y estudiar sus rangos de normalidad. Dichos rangos permiten valorar de forma objetiva la función regional de cualquier nuevo paciente. Para ello, consideramos secuencias de resonancia magnética etiquetada a nivel basal, medio y apical. Los hiperparámetros se obtienen a partir del movimiento intramural del VI estimado mediante el método Harmonic Phase Flow. El DPN se define a partir de en una parametrización del Ventrículo Izquierdo (VI) en sus coordenadas radiales y circunferencial basada en criterios anatómicos. El paso de los hiperparámetros al DPN hace posible la comparación entre distintos pacientes. Los rangos de normalidad se definen mediante análisis estadístico de valores de voluntarios sanos en 45 regiones del DPN a lo largo de 9 fases sistólicas. Se ha usado un conjunto de 19 (14 H; E: 30.7±7.5) voluntarios sanos para crear los patrones de normalidad y se han validado usando 2 controles sanos y 3 pacientes afectados de contractilidad global reducida. Para los controles los resultados regionales se han ajustado dentro de la normalidad, mientras que para los pacientes se han obtenido valores anormales en las zonas descritas, localizando y cuantificando así el diagnóstico empírico. |
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IAM @ iam @ GRP2008 |
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1032 |
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Author |
Jaume Garcia; Debora Gil; Sandra Pujades; Francesc Carreras |
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Title |
A Variational Framework for Assessment of the Left Ventricle Motion |
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Journal Article |
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2008 |
Publication |
International Journal Mathematical Modelling of Natural Phenomena |
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3 |
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6 |
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76-100 |
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Key words: Left Ventricle Dynamics, Ventricular Torsion, Tagged Magnetic Resonance, Motion Tracking, Variational Framework, Gabor Transform. |
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Impairment of left ventricular contractility due to cardiovascular diseases is reflected in left ventricle (LV) motion patterns. An abnormal change of torsion or long axis shortening LV values can help with the diagnosis and follow-up of LV dysfunction. Tagged Magnetic Resonance (TMR) is a widely spread medical imaging modality that allows estimation of the myocardial tissue local deformation. In this work, we introduce a novel variational framework for extracting the left ventricle dynamics from TMR sequences. A bi-dimensional representation space of TMR images given by Gabor filter banks is defined. Tracking of the phases of the Gabor response is combined using a variational framework which regularizes the deformation field just at areas where the Gabor amplitude drops, while restoring the underlying motion otherwise. The clinical applicability of the proposed method is illustrated by extracting normality models of the ventricular torsion from 19 healthy subjects. |
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IAM @ iam @ GGC2008a |
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1058 |
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Author |
Enric Marti; Jaume Rocarias; Debora Gil; Marc Vivet; Carme Julia |
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Uso de recursos virtuales en Aprendizaje Basado en Proyectos. Una experiencia en la asignatura de Graficos por Computador |
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Miscellaneous |
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2008 |
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Octava Jornada sobre Aprendizaje Cooperativo |
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79–88 |
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En esta comunicación presentamos una experiencia en Aprendizaje Basado en Proyectos (Project
Based Learning – PBL) realizada los últimos cuatro años (cursos del 2004-05 al 2007-08) en Gráficos
por Computador 2, asignatura optativa de tercer curso de Ingeniería Informática, titulación impartida
en la Escuela Técnica Superior de Ingeniería (ETSE) de la Universidad Autónoma de Barcelona
(UAB).
Fruto de la constante voluntad de mejora de la organización ABP de nuestra asignatura nos decidimos
a utilizar una herramienta LMS (Learning Management System) basada en Moodle y adaptada por
nosotros llamada Caronte para poder gestionar la documentación generada en ABP, y añadir una
componente semipresencial a la asignatura.
En primer lugar se presenta la organización de nuestra asignatura, basada proponer al alumno dos
itinerarios para cursarla: el itinerario ABP y el itinerario basado en clases magistrales i examen que
llamaremos TPPE (Teoría, Problemas, Prácticas, Examen). La dinámica ABP nos genera una cantidad
importante de documentación entre los grupos y el profesor, aparte de el feedback que el profesor
genera a los alumnos.
En la segunda parte del artículo presentamos los espacios docentes electrónicos de ambos itinerarios,
con los que trabajan los alumnos.
Finalmente, mostramos los resultados obtenidos de alumnos matriculados y de encuestas de valoración
realizados por los alumnos para finalmente exponer las conclusiones de estos cuatro años de
experiencia en ABP y en el uso de recursos virtuales en ABP, así como plantear mejoras y temas de
discusión sobre ABP. |
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Lleida |
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978-84-691-4605-7 |
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IAM;ADAS; |
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IAM @ iam @ MRG2008a |
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1101 |
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Enric Marti; Carme Julia; Debora Gil |
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Una experiencia de PBL en la docencia de la asignatura de Graficos por Computador en Ingenieria Informatica |
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Miscellaneous |
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2006 |
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IV Congreso Internacional Docencia Universitaria e Innovacion (CIDUI´06) |
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Barcelona |
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IAM;ADAS; |
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IAM @ iam @ MJG2006b |
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1123 |
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Mariano Vazquez; Ruth Aris; Guillaume Hozeaux; R.Aubry; P.Villar;Jaume Garcia ; Debora Gil; Francesc Carreras |
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A massively parallel computational electrophysiology model of the heart |
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Journal Article |
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2011 |
Publication |
International Journal for Numerical Methods in Biomedical Engineering |
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IJNMBE |
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27 |
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1911-1929 |
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computational electrophysiology; parallelization; finite element methods |
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This paper presents a patient-sensitive simulation strategy capable of using the most efficient way the high-performance computational resources. The proposed strategy directly involves three different players: Computational Mechanics Scientists (CMS), Image Processing Scientists and Cardiologists, each one mastering its own expertise area within the project. This paper describes the general integrative scheme but focusing on the CMS side presents a massively parallel implementation of computational electrophysiology applied to cardiac tissue simulation. The paper covers different angles of the computational problem: equations, numerical issues, the algorithm and parallel implementation. The proposed methodology is illustrated with numerical simulations testing all the different possibilities, ranging from small domains up to very large ones. A key issue is the almost ideal scalability not only for large and complex problems but also for medium-size meshes. The explicit formulation is particularly well suited for solving this highly transient problems, with very short time-scale. |
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Swansea (UK) |
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John Wiley & Sons, Ltd. |
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John Wiley & Sons, Ltd. |
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IAM @ iam @ VAH2011 |
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1198 |
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Albert Andaluz; Francesc Carreras; Debora Gil; Jaume Garcia |
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Una aplicació amigable pel càlcul de indicadors clínics del ventricle esquerre |
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2010 |
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Forum Biocat 2010 |
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Lonja de Mar,Barcelona (Spain) |
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CVC |
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Biocat |
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Barcelona |
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Catalan |
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IAM @ iam @ ACG2010 |
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1483 |
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Cristina Cañero; Petia Radeva; Oriol Pujol; Ricardo Toledo; Debora Gil; J. Saludes; Juan J. Villanueva; B. Garcia del Blanco; J. Mauri; E. Fernandez-Nofrerias; J.A. Gomez-Hospital; E. Iraculis; J. Comin; C. Quiles; F. Jara; A. Cequier; E. Esplugas |
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Optimal Stent Implantation: Three-dimensional Evaluation of the Mutual Position of Stent and Vessel via Intracoronary Ecography |
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1999 |
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Proceedings of International Conference on Computer in Cardiology (CIC´99) |
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We present a new automatic technique to visualize and quantify the mutual position between the stent and the vessel wall by considering their three-dimensional reconstruction. Two deformable generalized cylinders adapt to the image features in all IVUS planes corresponding to the vessel wall and the stent in order to reconstruct the boundaries of the stent and the vessel in space. The image features that characterize the stent and the vessel wall are determined in terms of edge and ridge image detectors taking into account the gray level of the image pixels. We show that the 30 reconstruction by deformable cylinders is accurate and robust due to the spatial data coherence in the considered volumetric IVUS image. The main clinic utility of the stent and vessel reconstruction by deformable’ cylinders consists of its possibility to visualize and to assess the optimal stent introduction. |
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IAM @ iam @ CRP1999a |
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1491 |
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Debora Gil; Jordi Gonzalez; Gemma Sanchez (eds) |
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Computer Vision: Advances in Research and Development |
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2007 |
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Proceedings of the 2nd CVC International Workshop |
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UAB |
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Bellaterra (Spain) |
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Debora Gil; Jordi Gonzalez; Gemma Sanchez |
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978-84-935251-4-9 |
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IAM; ISE; DAG |
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IAM @ iam @ GGS2007 |
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1493 |
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Francesc Carreras; Jaume Garcia; Debora Gil; Sandra Pujadas; Chi ho Lion; R.Suarez-Arias; R.Leta; Xavier Alomar; Manuel Ballester; Guillem Pons-Llados |
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Left ventricular torsion and longitudinal shortening: two fundamental components of myocardial mechanics assessed by tagged cine-MRI in normal subjects |
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2012 |
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International Journal of Cardiovascular Imaging |
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IJCI |
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28 |
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2 |
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273-284 |
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Magnetic resonance imaging (MRI); Tagging MRI; Cardiac mechanics; Ventricular torsion |
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Cardiac magnetic resonance imaging (Cardiac MRI) has become a gold standard diagnostic technique for the assessment of cardiac mechanics, allowing the non-invasive calculation of left ventric- ular long axis longitudinal shortening (LVLS) and absolute myocardial torsion (AMT) between basal and apical left ventricular slices, a movement directly related to the helicoidal anatomic disposition of the myocardial fibers. The aim of this study is to determine AMT and LVLS behaviour and normal values from a group of healthy subjects. A group of 21 healthy volunteers (15 males) (age: 23–55 y.o., mean:30.7 ± 7.5) were prospectively included in an obser- vational study by Cardiac MRI. Left ventricular rotation (degrees) was calculated by custom-made software (Harmonic Phase Flow) in consecutive LV short axis planes tagged cine-MRI sequences. AMT was determined from the difference between basal and apical planes LV rotations. LVLS (%) was determined from the LV longitudinal and horizontal axis cine-MRI images. All the 21 cases studied were interpretable, although in three cases the value of the LV apical rotation could not be determined. The mean rotation of the basal and apical planes at end-systole were -3.71° ± 0.84° and 6.73° ± 1.69° (n:18) respectively, resulting in a LV mean AMT of 10.48° ± 1.63° (n:18). End-systolic mean LVLS was 19.07 ± 2.71%. Cardiac MRI allows for the calculation of AMT and LVLS, fundamental functional components of the ventricular twist mechanics conditioned, in turn, by the anatomical helical layout of the myocardial fibers. These values provide complementary information about systolic ventricular function in relation to the traditional parameters used in daily practice. |
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Springer Netherlands |
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IAM @ iam @ CGG2012 |
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1496 |
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Jaume Garcia; Debora Gil; Francesc Carreras; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados |
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Patrons de Normalitat Regional per la Valoració de la Funció del Ventricle Esquerre |
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2008 |
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XX Congrés de la Societat Catalana de Cardiologia |
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60 |
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Les malalties cardiovasculars afecten les propietats contràctils de la banda ventricular i provoquen una variació de la funció del Ventricle Esquerre (VE) . Només els indicadors locals (strains, la deformació del teixit) són capaços de detectar anomalies en territoris específics del VE . Patrons de normalitat regionals d’aquests paràmetres serien d’utilitat a l’hora de valorar-ne la funció .
Presentem un Domini Paramètric Normalitzat (DPN) que permet comparar dades de diferents pacients i definir Patrons de Normalitat Regional (PNR) |
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IAM @ iam @ GGC2008b |
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1503 |
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Jaume Garcia; Debora Gil; Francesc Carreras ; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados |
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Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat |
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2008 |
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XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres |
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122 |
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Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica |
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IAM @ iam @ GGC2008c |
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1504 |
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Jaume Garcia; Debora Gil; Francesc Carreras; Sandra Pujades; R.Leta |
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Modelització 4-Dimensional de la Funció Siatólica del Ventricle Esquerre |
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2007 |
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XIX Congrés de la Societat Catalana de Cardiologia de Barcelona |
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133-134 |
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L’evolució tecnològica en el tractament de les imatges mèdiques permet reconstruir, amb el software apropiat, imatges tridimensionals de les estructures cardiovasculars i dotar-les de moviment. Les imatges 4D resultants faciliten l’estudi de la fisiopatologia de la insuficiència cardíaca en base als transtorns de l’activació electromecànica ventricular, el que pot ser d’interès en el procés de selecció de pacients candidats a teràpies de resincronització. Presentem els resultats preliminars de la reconstrucció 4D del ventricle esquerre (VE) a partir de les seqüències de tagging miocàrdic del VE. |
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IAM @ iam @ GGC2007 |
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