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Author Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux edit   pdf
url  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type (up) Conference Article
  Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance.  
  Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Venezia (Italia) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN B-31470-08 ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGV2008c Serial 1521  
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Author Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti edit   pdf
url  doi
openurl 
  Title Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy Type (up) Conference Article
  Year 2010 Publication 8th Medical Imaging Abbreviated Journal  
  Volume 7623 Issue 762304 Pages 304  
  Keywords  
  Abstract Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature.  
  Address  
  Corporate Author Thesis  
  Publisher SPIE Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference SPIE  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGH2010a Serial 1522  
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Author Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva edit   pdf
openurl 
  Title A Deterministic-Statistic Adventitia Detection in IVUS Images Type (up) Conference Article
  Year 2005 Publication ESC Congress Abbreviated Journal  
  Volume Issue Pages  
  Keywords Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation  
  Abstract Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.  
  Address Stockholm; Sweden; September 2005  
  Corporate Author Thesis  
  Publisher Place of Publication ,Sweden (EU) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference ESC  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RMF2005a Serial 1523  
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Author Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva edit   pdf
doi  openurl
  Title A Deterministic-Statistic Adventitia Detection in IVUS Images Type (up) Conference Article
  Year 2005 Publication 3rd International workshop on International Workshop on Functional Imaging and Modeling of the Heart Abbreviated Journal  
  Volume Issue Pages 65-74  
  Keywords Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation  
  Abstract Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.  
  Address Barcelona; June 2005  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference FIMH  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RMF2005 Serial 1524  
Permanent link to this record
 

 
Author Debora Gil; Aura Hernandez-Sabate; Mireia Burnat; Steven Jansen; Jordi Martinez-Vilalta edit   pdf
doi  isbn
openurl 
  Title Structure-Preserving Smoothing of Biomedical Images Type (up) Conference Article
  Year 2009 Publication 13th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal  
  Volume 5702 Issue Pages 427-434  
  Keywords non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography.  
  Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.  
  Address Münster, Germany  
  Corporate Author Thesis  
  Publisher Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-03766-5 Medium  
  Area Expedition Conference CAIP  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GHB2009 Serial 1527  
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Author Debora Gil; Oriol Rodriguez; Josepa Mauri; Petia Radeva edit  openurl
  Title Statistical descriptors of the Myocardial perfusion in angiographic images Type (up) Conference Article
  Year 2006 Publication Proc. Computers in Cardiology Abbreviated Journal  
  Volume Issue Pages 677-680  
  Keywords Anisotropic processing; intravascular ultrasound (IVUS); vessel border segmentation; vessel structure classification.  
  Abstract Restoration of coronary flow after primary percutaneous coronary intervention in acute myocardial infarction does not always correlate with adequate myocardial perfusion. Recently, coronary angiography has been used to assess microcirculation integrity (Myocardial BlushAnalysis, MBA). Although MBA correlates with patient prognosis there are few image processing methods addressing objective perfusion quantification. The goal of this work is to develop statistical descriptors of the myocardial dyeing pattern allowing objective assessment of myocardial perfusion. Experiments on healthy right coronary arteries show that our approach allows reliable measurements without any specific image acquisition protocol.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GRR2006 Serial 1528  
Permanent link to this record
 

 
Author Debora Gil; Petia Radeva; Josefina Mauri edit   pdf
openurl 
  Title Ivus Segmentation Via a Regularized Curvature Flow Type (up) Conference Article
  Year 2002 Publication X Congreso Anual de la Sociedad Española de Ingeniería Biomédica CASEIB 2002 Abbreviated Journal  
  Volume Issue Pages 133-136  
  Keywords  
  Abstract Cardiac diseases are diagnosed and treated through a study of the morphology and dynamics of cardiac arteries. In- travascular Ultrasound (IVUS) imaging is of high interest to physicians since it provides both information. At the current state-of-the-art in image segmentation, a robust detection of the arterial lumen in IVUS demands manual intervention or ECG-gating. Manual intervention is a tedious and time consuming task that requires experienced observers, meanwhile ECG-gating is an acquisition technique not available in all clinical centers. We introduce a parametric algorithm that detects the arterial luminal border in in vivo sequences. The method consist in smoothing the sequences’ level surfaces under a regularized mean curvature flow that admits non-trivial steady states. The flow is based on a measure of the surface local smoothness that takes into account regularity of the surface curvature.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Saragossa, Espanya Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GRM2002 Serial 1536  
Permanent link to this record
 

 
Author Debora Gil; Petia Radeva; Jordi Saludes; Josefina Mauri edit   pdf
url  openurl
  Title Automatic Segmentation of Artery Wall in Coronary IVUS Images: A Probabilistic Approach Type (up) Conference Article
  Year 2000 Publication International Conference on Pattern Recognition Abbreviated Journal  
  Volume 4 Issue Pages 352-355  
  Keywords  
  Abstract Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GRS2000a Serial 1537  
Permanent link to this record
 

 
Author Debora Gil; Petia Radeva; Jordi Saludes; Josefina Mauri edit   pdf
openurl 
  Title Automatic Segmentation of Artery Wall in Coronary IVUS Images: a Probabilistic Approach Type (up) Conference Article
  Year 2000 Publication Proceedings of CIC’2000 Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Cambridge, Massachussets Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CIC  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ GRS2000 Serial 1538  
Permanent link to this record
 

 
Author Debora Gil; Petia Radeva; Fernando Vilariño edit   pdf
isbn  openurl
  Title Anisotropic Contour Completion Type (up) Conference Article
  Year 2003 Publication Proceedings of the IEEE International Conference on Image Processing Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract In this paper we introduce a novel application of the diffusion tensor for anisotropic image processing. The Anisotropic Contour Completion (ACC) we suggest consists in extending the characteristic function of the open curve by means of a degenerated diffusion tensor that prevents any diffusion in the normal direction. We show that ACC is equivalent to a dilation with a continuous elliptic structural element that takes into account the local orientation of the contours to be closed. Experiments on contours extracted from real images show that ACC produces shapes able to adapt to any curve in an active contour framework. 1.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona, Spain Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 0-7803-7751-6 Medium  
  Area Expedition Conference  
  Notes IAM;MV;MILAB Approved no  
  Call Number IAM @ iam @ GRV2003 Serial 1539  
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