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Author Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit   pdf
openurl 
  Title On the usefulness of supervised learning for vessel border detection in IntraVascular Imaging Type Conference Article
  Year 2005 Publication Proceeding of the 2005 conference on Artificial Intelligence Research and Development Abbreviated Journal  
  Volume Issue Pages 67-74  
  Keywords classification; vessel border modelling; IVUS  
  Abstract IntraVascular UltraSound (IVUS) imaging is a useful tool in diagnosis of cardiac diseases since sequences completely show the morphology of coronary vessels. Vessel borders detection, especially the external adventitia layer, plays a central role in morphological measures and, thus, their segmentation feeds development of medical imaging techniques. Deterministic approaches fail to yield optimal results due to the large amount of IVUS artifacts and vessel borders descriptors. We propose using classification techniques to learn the set of descriptors and parameters that best detect vessel borders. Statistical hypothesis test on the error between automated detections and manually traced borders by 4 experts show that our detections keep within inter-observer variability.  
  Address  
  Corporate Author Thesis  
  Publisher (up) IOS Press Place of Publication Amsterdam, The Netherlands Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ HGR2005c Serial 1549  
Permanent link to this record
 

 
Author David Roche; Debora Gil; Jesus Giraldo edit   pdf
url  openurl
  Title Assessing agonist efficacy in an uncertain Em world Type Conference Article
  Year 2012 Publication 40th Keystone Symposia on mollecular and celular biology Abbreviated Journal  
  Volume Issue Pages 79  
  Keywords  
  Abstract The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.
 
  Address Fairmont Banff Springs, Banff, Alberta, Canada  
  Corporate Author Keystone Symposia Thesis  
  Publisher (up) Keystone Symposia Place of Publication Editor A. Christopoulus and M. Bouvier  
  Language english Summary Language english Original Title  
  Series Editor Keystone Symposia Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference KSMCB  
  Notes IAM Approved no  
  Call Number IAM @ iam @ RGG2012 Serial 1855  
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Author Carles Sanchez; Debora Gil; Antoni Rosell; Albert Andaluz; F. Javier Sanchez edit   pdf
isbn  openurl
  Title Segmentation of Tracheal Rings in Videobronchoscopy combining Geometry and Appearance Type Conference Article
  Year 2013 Publication Proceedings of the International Conference on Computer Vision Theory and Applications Abbreviated Journal  
  Volume 1 Issue Pages 153--161  
  Keywords Video-bronchoscopy, tracheal ring segmentation, trachea geometric and appearance model  
  Abstract Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways and minimal invasive interventions. Tracheal procedures are ordinary interventions that require measurement of the percentage of obstructed pathway for injury (stenosis) assessment. Visual assessment of stenosis in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error. Accurate detection of tracheal rings is the basis for automated estimation of the size of stenosed trachea. Processing of videobronchoscopic images acquired at the operating room is a challenging task due to the wide range of artifacts and acquisition conditions. We present a model of the geometric-appearance of tracheal rings for its detection in videobronchoscopic videos. Experiments on sequences acquired at the operating room, show a performance close to inter-observer variability  
  Address Barcelona; February 2013  
  Corporate Author Thesis  
  Publisher (up) SciTePress Place of Publication Portugal Editor Sebastiano Battiato and José Braz  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-989-8565-47-1 Medium  
  Area 800 Expedition Conference VISAPP  
  Notes IAM;MV; 600.044; 600.047; 600.060; 605.203 Approved no  
  Call Number IAM @ iam @ SGR2013 Serial 2123  
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Author Joan M. Nuñez; Debora Gil; Fernando Vilariño edit  doi
openurl 
  Title Finger joint characterization from X-ray images for rheymatoid arthritis assessment Type Conference Article
  Year 2013 Publication 6th International Conference on Biomedical Electronics and Devices Abbreviated Journal  
  Volume Issue Pages 288-292  
  Keywords Rheumatoid Arthritis; X-Ray; Hand Joint; Sclerosis; Sharp Van der Heijde  
  Abstract In this study we propose amodular systemfor automatic rheumatoid arthritis assessment which provides a joint space width measure. A hand joint model is proposed based on the accurate analysis of a X-ray finger joint image sample set. This model shows that the sclerosis and the lower bone are the main necessary features in order to perform a proper finger joint characterization. We propose sclerosis and lower bone detection methods as well as the experimental setup necessary for its performance assessment. Our characterization is used to propose and compute a joint space width score which is shown to be related to the different degrees of arthritis. This assertion is verified by comparing our proposed score with Sharp Van der Heijde score, confirming that the lower our score is the more advanced is the patient affection.  
  Address Barcelona; February 2013  
  Corporate Author Thesis  
  Publisher (up) SciTePress Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area 800 Expedition Conference BIODEVICES  
  Notes IAM;MV; 600.057; 600.054 Approved no  
  Call Number IAM @ iam @ NGV2013 Serial 2196  
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Author Antoni Gurgui; Debora Gil; Enric Marti edit  url
doi  isbn
openurl 
  Title Laplacian Unitary Domain for Texture Morphing Type Conference Article
  Year 2015 Publication Proceedings of the 10th International Conference on Computer Vision Theory and Applications VISIGRAPP2015 Abbreviated Journal  
  Volume 1 Issue Pages 693-699  
  Keywords Facial; metamorphosis;LaplacianMorphing  
  Abstract Deformation of expressive textures is the gateway to realistic computer synthesis of expressions. By their good mathematical properties and flexible formulation on irregular meshes, most texture mappings rely on solutions to the Laplacian in the cartesian space. In the context of facial expression morphing, this approximation can be seen from the opposite point of view by neglecting the metric. In this paper, we use the properties of the Laplacian in manifolds to present a novel approach to warping expressive facial images in order to generate a morphing between them.  
  Address Munich; Germany; February 2015  
  Corporate Author Thesis  
  Publisher (up) SciTePress Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-989-758-089-5 Medium  
  Area Expedition Conference VISAPP  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ GGM2015 Serial 2614  
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Author Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti edit   pdf
url  doi
openurl 
  Title Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy Type Conference Article
  Year 2010 Publication 8th Medical Imaging Abbreviated Journal  
  Volume 7623 Issue 762304 Pages 304  
  Keywords  
  Abstract Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature.  
  Address  
  Corporate Author Thesis  
  Publisher (up) SPIE Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference SPIE  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGH2010a Serial 1522  
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Author Debora Gil; Aura Hernandez-Sabate; Mireia Burnat; Steven Jansen; Jordi Martinez-Vilalta edit   pdf
doi  isbn
openurl 
  Title Structure-Preserving Smoothing of Biomedical Images Type Conference Article
  Year 2009 Publication 13th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal  
  Volume 5702 Issue Pages 427-434  
  Keywords non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography.  
  Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.  
  Address Münster, Germany  
  Corporate Author Thesis  
  Publisher (up) Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-03766-5 Medium  
  Area Expedition Conference CAIP  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GHB2009 Serial 1527  
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Author Debora Gil; Agnes Borras; Sergio Vera; Miguel Angel Gonzalez Ballester edit   pdf
doi  isbn
openurl 
  Title A Validation Benchmark for Assessment of Medial Surface Quality for Medical Applications Type Conference Article
  Year 2013 Publication 9th International Conference on Computer Vision Systems Abbreviated Journal  
  Volume 7963 Issue Pages 334-343  
  Keywords Medial Surfaces; Shape Representation; Medical Applications; Performance Evaluation  
  Abstract Confident use of medial surfaces in medical decision support systems requires evaluating their quality for detecting pathological deformations and describing anatomical volumes. Validation in the medical imaging field is a challenging task mainly due to the difficulties for getting consensual ground truth. In this paper we propose a validation benchmark for assessing medial surfaces in the context of medical applications. Our benchmark includes a home-made database of synthetic medial surfaces and volumes and specific scores for evaluating surface accuracy, its stability against volume deformations and its capabilities for accurate reconstruction of anatomical volumes.  
  Address Sant Petersburg; Russia; July 2013  
  Corporate Author Thesis  
  Publisher (up) Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-39401-0 Medium  
  Area Expedition Conference ICVS  
  Notes IAM; 600.044; 600.060 Approved no  
  Call Number Admin @ si @ GBV2013 Serial 2300  
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Author Ferran Poveda; Debora Gil;Enric Marti edit   pdf
doi  isbn
openurl 
  Title Multi-resolution DT-MRI cardiac tractography Type Conference Article
  Year 2012 Publication Statistical Atlases And Computational Models Of The Heart: Imaging and Modelling Challenges Abbreviated Journal  
  Volume 7746 Issue Pages 270-277  
  Keywords  
  Abstract Even using objective measures from DT-MRI no consensus about myocardial architecture has been achieved so far. Streamlining provides good reconstructions at low level of detail, but falls short to give global abstract interpretations. In this paper, we present a multi-resolution methodology that is able to produce simplified representations of cardiac architecture. Our approach produces a reduced set of tracts that are representative of the main geometric features of myocardial anatomical structure. Experiments show that fiber geometry is preserved along reductions, which validates the simplified model for interpretation of cardiac architecture.  
  Address Nice, France  
  Corporate Author Thesis  
  Publisher (up) Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-36960-5 Medium  
  Area Expedition Conference STACOM  
  Notes IAM Approved no  
  Call Number IAM @ iam @ PGM2012 Serial 1986  
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Author Debora Gil;Agnes Borras;Ruth Aris;Mariano Vazquez;Pierre Lafortune; Guillame Houzeaux edit   pdf
doi  isbn
openurl 
  Title What a difference in biomechanics cardiac fiber makes Type Conference Article
  Year 2012 Publication Statistical Atlases And Computational Models Of The Heart: Imaging and Modelling Challenges Abbreviated Journal  
  Volume 7746 Issue Pages 253-260  
  Keywords  
  Abstract Computational simulations of the heart are a powerful tool for a comprehensive understanding of cardiac function and its intrinsic relationship with its muscular architecture. Cardiac biomechanical models require a vector field representing the orientation of cardiac fibers. A wrong orientation of the fibers can lead to a
non-realistic simulation of the heart functionality. In this paper we explore the impact of the fiber information on the simulated biomechanics of cardiac muscular anatomy. We have used the John Hopkins database to perform a biomechanical simulation using both a synthetic benchmark fiber distribution and the data obtained experimentally from DTI. Results illustrate how differences in fiber orientation affect heart deformation along cardiac cycle.
 
  Address Nice, France  
  Corporate Author Thesis  
  Publisher (up) Springer Berlin Heidelberg Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-642-36960-5 Medium  
  Area Expedition Conference STACOM  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GBA2012 Serial 1987  
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