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Author |
Debora Gil; Jaume Garcia; Mariano Vazquez; Ruth Aris; Guilleaume Houzeaux |
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Title |
Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function |
Type |
Conference Article |
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Year |
2008 |
Publication  |
8th World Congress on Computational Mechanichs (WCCM8) |
Abbreviated Journal |
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Keywords |
Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance. |
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Abstract |
Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model. |
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Venice; Italy |
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9788496736559 |
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IAM; |
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IAM @ iam @ GGV2008b |
Serial |
993 |
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Author |
Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux |
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Title |
Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function |
Type |
Conference Article |
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Year |
2008 |
Publication |
8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) |
Abbreviated Journal |
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Issue |
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Keywords |
Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance. |
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Abstract |
Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model. |
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Venezia (Italia) |
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B-31470-08 |
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IAM @ iam @ GGV2008c |
Serial |
1521 |
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Author |
Debora Gil; Agnes Borras; Sergio Vera; Miguel Angel Gonzalez Ballester |
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Title |
A Validation Benchmark for Assessment of Medial Surface Quality for Medical Applications |
Type |
Conference Article |
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Year |
2013 |
Publication |
9th International Conference on Computer Vision Systems |
Abbreviated Journal |
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Volume |
7963 |
Issue |
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Pages |
334-343 |
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Keywords |
Medial Surfaces; Shape Representation; Medical Applications; Performance Evaluation |
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Abstract |
Confident use of medial surfaces in medical decision support systems requires evaluating their quality for detecting pathological deformations and describing anatomical volumes. Validation in the medical imaging field is a challenging task mainly due to the difficulties for getting consensual ground truth. In this paper we propose a validation benchmark for assessing medial surfaces in the context of medical applications. Our benchmark includes a home-made database of synthetic medial surfaces and volumes and specific scores for evaluating surface accuracy, its stability against volume deformations and its capabilities for accurate reconstruction of anatomical volumes. |
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Address |
Sant Petersburg; Russia; July 2013 |
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Publisher |
Springer Berlin Heidelberg |
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LNCS |
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ISSN |
0302-9743 |
ISBN |
978-3-642-39401-0 |
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ICVS |
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Notes |
IAM; 600.044; 600.060 |
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Call Number |
Admin @ si @ GBV2013 |
Serial |
2300 |
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Author |
Patricia Marquez; Debora Gil; Aura Hernandez-Sabate; Daniel Kondermann |
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Title |
When Is A Confidence Measure Good Enough? |
Type |
Conference Article |
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Year |
2013 |
Publication |
9th International Conference on Computer Vision Systems |
Abbreviated Journal |
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Volume |
7963 |
Issue |
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Pages |
344-353 |
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Keywords |
Optical flow, confidence measure, performance evaluation |
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Abstract |
Confidence estimation has recently become a hot topic in image processing and computer vision.Yet, several definitions exist of the term “confidence” which are sometimes used interchangeably. This is a position paper, in which we aim to give an overview on existing definitions,
thereby clarifying the meaning of the used terms to facilitate further research in this field. Based on these clarifications, we develop a theory to compare confidence measures with respect to their quality. |
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Address |
St Petersburg; Russia; July 2013 |
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Springer Link |
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LNCS |
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0302-9743 |
ISBN |
978-3-642-39401-0 |
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ICVS |
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Notes |
IAM;ADAS; 600.044; 600.057; 600.060; 601.145 |
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Call Number |
IAM @ iam @ MGH2013a |
Serial |
2218 |
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Author |
Patricia Marquez; Debora Gil; R.Mester; Aura Hernandez-Sabate |
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Title |
Local Analysis of Confidence Measures for Optical Flow Quality Evaluation |
Type |
Conference Article |
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Year |
2014 |
Publication |
9th International Conference on Computer Vision Theory and Applications |
Abbreviated Journal |
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Volume |
3 |
Issue |
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Pages |
450-457 |
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Keywords |
Optical Flow; Confidence Measure; Performance Evaluation. |
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Abstract |
Optical Flow (OF) techniques facing the complexity of real sequences have been developed in the last years. Even using the most appropriate technique for our specific problem, at some points the output flow might fail to achieve the minimum error required for the system. Confidence measures computed from either input data or OF output should discard those points where OF is not accurate enough for its further use. It follows that evaluating the capabilities of a confidence measure for bounding OF error is as important as the definition
itself. In this paper we analyze different confidence measures and point out their advantages and limitations for their use in real world settings. We also explore the agreement with current tools for their evaluation of confidence measures performance. |
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Lisboa; January 2014 |
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VISAPP |
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IAM; ADAS; 600.044; 600.060; 600.057; 601.145; 600.076; 600.075 |
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no |
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Call Number |
Admin @ si @ MGM2014 |
Serial |
2432 |
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Author |
Patricia Marquez; Debora Gil ; Aura Hernandez-Sabate |
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Title |
Error Analysis for Lucas-Kanade Based Schemes |
Type |
Conference Article |
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Year |
2012 |
Publication |
9th International Conference on Image Analysis and Recognition |
Abbreviated Journal |
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Volume |
7324 |
Issue |
I |
Pages |
184-191 |
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Keywords |
Optical flow, Confidence measure, Lucas-Kanade, Cardiac Magnetic Resonance |
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Abstract |
Optical flow is a valuable tool for motion analysis in medical imaging sequences. A reliable application requires determining the accuracy of the computed optical flow. This is a main challenge given the absence of ground truth in medical sequences. This paper presents an error analysis of Lucas-Kanade schemes in terms of intrinsic design errors and numerical stability of the algorithm. Our analysis provides a confidence measure that is naturally correlated to the accuracy of the flow field. Our experiments show the higher predictive value of our confidence measure compared to existing measures. |
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Aveiro, Portugal |
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Springer-Verlag Berlin Heidelberg |
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english |
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Campilho, Aurélio and Kamel, Mohamed |
Series Title |
Lecture Notes in Computer Science |
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LNCS |
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0302-9743 |
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978-3-642-31294-6 |
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ICIAR |
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IAM |
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Call Number |
IAM @ iam @ MGH2012a |
Serial |
1899 |
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Author |
Jose Elias Yauri; Aura Hernandez-Sabate; Pau Folch; Debora Gil |
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Title |
Mental Workload Detection Based on EEG Analysis |
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Conference Article |
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Year |
2021 |
Publication |
Artificial Intelligent Research and Development. Proceedings 23rd International Conference of the Catalan Association for Artificial Intelligence. |
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Volume |
339 |
Issue |
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Pages |
268-277 |
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Keywords |
Cognitive states; Mental workload; EEG analysis; Neural Networks. |
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Abstract |
The study of mental workload becomes essential for human work efficiency, health conditions and to avoid accidents, since workload compromises both performance and awareness. Although workload has been widely studied using several physiological measures, minimising the sensor network as much as possible remains both a challenge and a requirement.
Electroencephalogram (EEG) signals have shown a high correlation to specific cognitive and mental states like workload. However, there is not enough evidence in the literature to validate how well models generalize in case of new subjects performing tasks of a workload similar to the ones included during model’s training.
In this paper we propose a binary neural network to classify EEG features across different mental workloads. Two workloads, low and medium, are induced using two variants of the N-Back Test. The proposed model was validated in a dataset collected from 16 subjects and shown a high level of generalization capability: model reported an average recall of 81.81% in a leave-one-out subject evaluation. |
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Virtual; October 20-22 2021 |
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CCIA |
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Notes |
IAM; 600.139; 600.118; 600.145 |
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no |
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Call Number |
Admin @ si @ |
Serial |
3723 |
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Author |
Jaume Garcia; Joel Barajas; Francesc Carreras; Sandra Pujades; Petia Radeva |
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Title |
An intuitive validation technique to compare local versus global tagged MRI analysis |
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Conference Article |
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Year |
2005 |
Publication |
Computers In Cardiology |
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32 |
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29–32 |
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Myocardium appears as a uniform tissue that seen in convectional Magnetic Resonance Images (MRI) shows just the contractile part of its movement. MR Tagging is a unique imaging technique that prints a grid over the tissue which moves according to the underlying movement of the myocardium revealing the true deformation of the cardiac muscle. Optical flow techniques based on spectral information estimate tissue displacement by analyzing information encoded in the phase maps which can be obtained using, local (Gabor) and global (HARP) methods. In this paper we compare both in synthetic and real Tagged MR sequences. We conclude that local method is slightly more accurate than the global one. On the other hand, global method is more efficient as it is much faster and less parameters have to be taken into account |
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Lyon (France) |
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0-7803-9337-6 |
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IAM;MILAB |
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IAM @ iam @ GBC2005 |
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639 |
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Author |
Aura Hernandez-Sabate; Monica Mitiko; Sergio Shiguemi; Debora Gil |
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Title |
A validation protocol for assessing cardiac phase retrieval in IntraVascular UltraSound |
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Conference Article |
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2010 |
Publication |
Computing in Cardiology |
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37 |
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899-902 |
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A good reliable approach to cardiac triggering is of utmost importance in obtaining accurate quantitative results of atherosclerotic plaque burden from the analysis of IntraVascular UltraSound. Although, in the last years, there has been an increase in research of methods for retrospective gating, there is no general consensus in a validation protocol. Many methods are based on quality assessment of longitudinal cuts appearance and those reporting quantitative numbers do not follow a standard protocol. Such heterogeneity in validation protocols makes faithful comparison across methods a difficult task. We propose a validation protocol based on the variability of the retrieved cardiac phase and explore the capability of several quality measures for quantifying such variability. An ideal detector, suitable for its application in clinical practice, should produce stable phases. That is, it should always sample the same cardiac cycle fraction. In this context, one should measure the variability (variance) of a candidate sampling with respect a ground truth (reference) sampling, since the variance would indicate how spread we are aiming a target. In order to quantify the deviation between the sampling and the ground truth, we have considered two quality scores reported in the literature: signed distance to the closest reference sample and distance to the right of each reference sample. We have also considered the residuals of the regression line of reference against candidate sampling. The performance of the measures has been explored on a set of synthetic samplings covering different cardiac cycle fractions and variabilities. From our simulations, we conclude that the metrics related to distances are sensitive to the shift considered while the residuals are robust against fraction and variabilities as far as one can establish a pair-wise correspondence between candidate and reference. We will further investigate the impact of false positive and negative detections in experimental data. |
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IEEE |
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0276-6547 |
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978-1-4244-7318-2 |
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CINC |
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IAM @ iam @ HSM2010 |
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1551 |
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Josefina Mauri; Eduard Fernandez-Nofrerias; B. Garcia del Blanco; E. Iraculis; J.A. Gomez-Hospital; J. Comin; M.A. Sanchez Corral; F. Jara; A. Cequier; E. Esplugas; Debora Gil; J. Saludes; Petia Radeva; Ricardo Toledo; Juan J.Villanueva |
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Moviment del vas en l anàlisi d imatges d ecografia intracoronària: un model matemàtic |
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2000 |
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Congrés de la Societat Catalana de Cardiologia. |
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IAM;RV;ISE;MILAB;ADAS |
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IAM @ iam @ MNG2000 |
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1621 |
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