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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Assessing agonist efficacy in an uncertain Em world |
Type |
Conference Article |
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Year |
2012 |
Publication |
40th Keystone Symposia on mollecular and celular biology |
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79 |
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The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed. |
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Fairmont Banff Springs, Banff, Alberta, Canada |
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Keystone Symposia |
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Keystone Symposia |
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A. Christopoulus and M. Bouvier |
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english |
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english |
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Keystone Symposia |
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KSMCB |
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IAM |
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IAM @ iam @ RGG2012 |
Serial |
1855 |
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Author |
Ernest Valveny; Enric Marti |
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Title |
Dimensions analysis in hand-drawn architectural drawings |
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Conference Article |
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Year |
1997 |
Publication |
VII National Simposium of Pattern Recognition and image Analysis, SNRFAI´97 |
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90-91 |
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DAG;IAM; |
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IAM @ iam @ VAM1997 |
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1659 |
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Author |
Gloria Fernandez Esparrach; Jorge Bernal; Cristina Rodriguez de Miguel; Debora Gil; Fernando Vilariño; Henry Cordova; Cristina Sanchez Montes; Isis Ara |
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Title |
Utilidad de la visión por computador para la localización de pólipos pequeños y planos |
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Conference Article |
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2016 |
Publication |
XIX Reunión Nacional de la Asociación Española de Gastroenterología, Gastroenterology Hepatology |
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39 |
Issue |
2 |
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94 |
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Madrid (Spain) |
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AEGASTRO |
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MV; IAM; 600.097;SIAI |
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no |
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Call Number |
Admin @ si @FBR2016 |
Serial |
2779 |
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Author |
Enric Marti; Debora Gil; Carme Julia |
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Title |
A PBL experience in the teaching of Computer Graphics |
Type |
Conference Article |
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Year |
2005 |
Publication |
EUROGRAPHICS Proceedings |
Abbreviated Journal |
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Volume |
5 |
Issue |
1 |
Pages |
95-103 |
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Keywords |
project-based learning; computer graphics education; Open GL; rendering techniques; computer animation techniques; Graphics packages; Hierarchy and geometric transformations; Animation; Color; shading; shadowing and texture; fractals; hidden line/surface removal; Problem Based Learning |
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Abstract |
Project-Based Learning (PBL) is an educational strategy to improve student’s learning capability that, in recent years, has had a progressive acceptance in undergraduate studies. This methodology is based on solving a problem or project in a student working group. In this way, PBL focuses on learning the necessary tools to correctly find a solution to given problems. Since the learning initiative is transferred to the student, the PBL method promotes students own abilities. This allows a better assessment of the true workload that carries out the student in the subject. It follows that the methodology conforms to the guidelines of the Bologna document, which quantifies the student workload in a subject by means of the European credit transfer system (ECTS). PBL is currently applied in undergraduate studies needing strong practical training such as medicine, nursing or law sciences. Although this is also the case in engineering studies, amazingly, few experiences have been reported. In this paper we propose to use PBL in the educational organization of the Computer Graphics subjects in the Computer Science degree. Our PBL project focuses in the development of a C++ graphical environment based on the OpenGL libraries for visualization and handling of different graphical objects. The starting point is a basic skeleton that already includes lighting functions, perspective projection with mouse interaction to change the point of view and three predefined objects. Students have to complete this skeleton by adding their own functions to solve the project. A total number of 10 projects have been proposed and successfully solved. The exercises range from human face rendering to articulated objects, such as robot arms or puppets. In the present paper we extensively report the statement and educational objectives for two of the projects: solar system visualization and a chess game. We report our earlier educational experience based on the standard classroom theoretical, problem and practice sessions and the reasons that motivated searching for other learning methods. We have mainly chosen PBL because it improves the student learning initiative. We have applied the PBL educational model since the beginning of the second semester. The student’s feedback increases in his interest for the subject. We present a comparative study of the teachers’ and students’ workload between PBL and the classic teaching approach, which suggests that the workload increase in PBL is not as high as it seems. |
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Dublin; Ireland; September 2005 |
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EUROGRAPHICS |
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IAM;ADAS; |
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no |
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Call Number |
IAM @ iam @ MGJ2005 |
Serial |
1593 |
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Author |
Enric Marti; Carme Julia; Debora Gil |
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Title |
A PBL Experience in the Teaching of Computer Graphics |
Type |
Conference Article |
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Year |
2007 |
Publication |
XVII Congreso Español de Informàtica Gráfica |
Abbreviated Journal |
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Volume |
25 |
Issue |
1 |
Pages |
95-103 |
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Keywords |
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Abstract |
Project-Based Learning (PBL) is an educational strategy to improve student’s learning capability that, in recent years, has had a progressive acceptance in undergraduate studies. This methodology is based on solving a problem or project in a student working group. In this way, PBL focuses on learning the necessary tools to correctly find a solution to given problems. Since the learning initiative is transferred to the student, the PBL method promotes students own abilities. This allows a better assessment of the true workload that carries out the student in the subject. It follows that the methodology conforms to the guidelines of the Bologna document, which quantifies the student workload in a subject by means of the European credit transfer system (ECTS). PBL is currently applied in undergraduate studies needing strong practical training such as medicine, nursing or law sciences. Although this is also the case in engineering studies, amazingly, few experiences have been reported. In this paper we propose to use PBL in the educational organization of the Computer Graphics subjects in the Computer Science degree. Our PBL project focuses in the development of a C++ graphical environment based on the OpenGL libraries for visualization and handling of different graphical objects. The starting point is a basic skeleton that already includes lighting functions, perspective projection with mouse interaction to change the point of view and three predefined objects. Students have to complete this skeleton by adding their own functions to solve the project. A total number of 10 projects have been proposed and successfully solved. The exercises range from human face rendering to articulated objects, such as robot arms or puppets. In the present paper we extensively report the statement and educational objectives for two of the projects: solar system visualization and a chess game. We report our earlier educational experience based on the standard classroom theoretical, problem and practice sessions and the reasons that motivated searching for other learning methods. We have mainly chosen PBL because it improves the student learning initiative. We have applied the PBL educational model since the beginning of the second semester. The student’s feedback increases in his interest for the subject. We present a comparative study of the teachers’ and students’ workload between PBL and the classic teaching approach, which suggests that the workload increase in PBL is not as high as it seems. |
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Zaragoza; September 2007 |
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CEDI |
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IAM;ADAS; |
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no |
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Call Number |
IAM @ iam @ MJG2007a |
Serial |
1603 |
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Author |
Joel Barajas; Jaume Garcia; Francesc Carreras; Sandra Pujades; Petia Radeva |
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Title |
Angle Images Using Gabor Filters in Cardiac Tagged MRI |
Type |
Conference Article |
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Year |
2005 |
Publication |
Proceeding of the 2005 conference on Artificial Intelligence Research and Development |
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107-114 |
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Keywords |
Angle Images, Gabor Filters, Harp, Tagged Mri |
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Abstract |
Tagged Magnetic Resonance Imaging (MRI) is a non-invasive technique used to examine cardiac deformation in vivo. An Angle Image is a representation of a Tagged MRI which recovers the relative position of the tissue respect to the distorted tags. Thus cardiac deformation can be estimated. This paper describes a new approach to generate Angle Images using a bank of Gabor filters in short axis cardiac Tagged MRI. Our method improves the Angle Images obtained by global techniques, like HARP, with a local frequency analysis. We propose to use the phase response of a combination of a Gabor filters bank, and use it to find a more precise deformation of the left ventricle. We demonstrate the accuracy of our method over HARP by several experimental results. |
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Address |
Amsterdam; The Netherlands |
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IOS Press |
Place of Publication |
Amsterdam, The Netherlands |
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1-58603-560-6 |
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CAIRD |
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Notes |
IAM;MILAB |
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no |
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Call Number |
BCNPCL @ bcnpcl @ BGC2005; IAM @ iam |
Serial |
595 |
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Author |
Joel Barajas; Jaume Garcia; Karla Lizbeth Caballero; Francesc Carreras; Sandra Pujades; Petia Radeva |
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Title |
Correction of Misalignment Artifacts Among 2-D Cardiac MR Images in 3-D Space |
Type |
Conference Article |
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Year |
2006 |
Publication |
1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) |
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Volume |
3217 |
Issue |
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Pages |
114-121 |
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Abstract |
Cardiac Magnetic Resonance images offer the opportunity to study the heart in detail. One of the main issues in its modelling is to create an accurate 3-D reconstruction of the left ventricle from 2-D views. A first step to achieve this goal is the correct registration among the different image planes due to patient movements. In this article, we present an accurate method to correct displacement artifacts using the Normalized Mutual Information. Here, the image views are treated as planes in order to diminish the approximation error caused by the association of a certain thickness, and moved simultaneously to avoid any kind of bias in the alignment process. This method has been validated using real and syntectic plane displacements, yielding promising results. |
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Copenhagen (Denmark) |
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978-3-540-22977-3 |
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IAM;MILAB |
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no |
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Call Number |
IAM @ iam @ BGC2006 |
Serial |
1485 |
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Author |
Jaume Garcia; Debora Gil; Francesc Carreras ; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados |
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Title |
Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat |
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Conference Article |
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Year |
2008 |
Publication |
XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres |
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122 |
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Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica |
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Barcelona |
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catalan |
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catalan |
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IAM |
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Call Number |
IAM @ iam @ GGC2008c |
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1504 |
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Author |
Patricia Marquez;Debora Gil;Aura Hernandez-Sabate |
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Title |
A Complete Confidence Framework for Optical Flow |
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Conference Article |
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Year |
2012 |
Publication |
12th European Conference on Computer Vision – Workshops and Demonstrations |
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7584 |
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2 |
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124-133 |
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Optical flow, confidence measures, sparsification plots, error prediction plots |
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Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations. |
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Springer-Verlag |
Place of Publication |
Florence, Italy, October 7-13, 2012 |
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Andrea Fusiello, Vittorio Murino ,Rita Cucchiara |
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LNCS |
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978-3-642-33867-0 |
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ECCVW |
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IAM;ADAS; |
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IAM @ iam @ MGH2012b |
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1991 |
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Author |
Oriol Rodriguez-Leon; Debora Gil; Eduard Fernandez-Nofrerias; H.Tizon; S.Montserrat; Vicente del Valle;Josefina Mauri |
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Title |
Caracterització de la Perfusió Miocàrdica mitjançant anàlisi estadístic de l espectre en l angiografia de contrast |
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Conference Article |
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Year |
2007 |
Publication |
XIX Congrés de la Societat Catalana de Cardiologia de Barcelona |
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130 |
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La valoració de la integritat de la microcirculació coronària aporta informació pronòstica en pacients amb infart agut de miocardi en els que es realitza angioplastia primària. Aquesta valoració és subjectiva i presenta una important variabilitat si no es duta a terme per personal experimentat. Presentem una eina d’anàlisi d’imatge que permet fer una valoració de la microcirculació coronària a partir de seqüències d’angiografia. Hem analitzat les variacions locals en el nivell de gris de la imatge durant la seqüència angiogràfica. Hem identificat els principals fenòmens observats (respiració, batec cardíac, tinció arterial, tinció miocàrdica i soroll radiològic) mitjançant un anàlisi estadístic de l’espectre de Fourier de l’evolució al llarg del temps de la mitja local. Aquest mateix anàlisis permet determinat la influència de cadascun d’ells en la extracció del patró de tinció i selecciona la respiració com el fenomen que més distorsiona el patró de tinció original. Els descriptors proposats s’obtenen fora del rang espectral respiratori. Hem testat la seva capacitat per a detectar els tres fenòmens principals (tinció miocàrdica (MS), tinció arterial (AS) i soroll (NS)) independentment de la respiració. La capacitat de discriminació dels descriptors ha estat valorada mitjançant un mètode de crossvalidation en 30 seqüències d’angiografia. Els descriptors emprats permeten caracteritzar la tinció miocàrdica amb una alta eficiència i fiabilitat. A més no hi ha diferències significatives en l’anàlisi de les seqüències obtingudes amb el pacient respirant amb normalitat o en apnea |
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Barcelona (Spain) |
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IAM |
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IAM @ iam @ RGF2007 |
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1639 |
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