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Author |
Antonio Esteban Lansaque |
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Title |
An Endoscopic Navigation System for Lung Cancer Biopsy |
Type |
Book Whole |
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Year |
2019 |
Publication |
PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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Lung cancer is one of the most diagnosed cancers among men and women. Actually,
lung cancer accounts for 13% of the total cases with a 5-year global survival
rate in patients. Although Early detection increases survival rate from 38% to 67%, accurate diagnosis remains a challenge. Pathological confirmation requires extracting a sample of the lesion tissue for its biopsy. The preferred procedure for tissue biopsy is called bronchoscopy. A bronchoscopy is an endoscopic technique for the internal exploration of airways which facilitates the performance of minimal invasive interventions with low risk for the patient. Recent advances in bronchoscopic devices have increased their use for minimal invasive diagnostic and intervention procedures, like lung cancer biopsy sampling. Despite the improvement in bronchoscopic device quality, there is a lack of intelligent computational systems for supporting in-vivo clinical decision during examinations. Existing technologies fail to accurately reach the lesion due to several aspects at intervention off-line planning and poor intra-operative guidance at exploration time. Existing guiding systems radiate patients and clinical staff,might be expensive and achieve a suboptimlal 70% of yield boost. Diagnostic yield could be improved reducing radiation and costs by developing intra-operative support systems able to guide the bronchoscopist to the lesion during the intervention. The goal of this PhD thesis is to develop an image-based navigation systemfor intra-operative guidance of bronchoscopists to a target lesion across a path previously planned on a CT-scan. We propose a 3D navigation system which uses the anatomy of video bronchoscopy frames to locate the bronchoscope within the airways. Once the bronchoscope is located, our navigation system is able to indicate the bifurcation which needs to be followed to reach the lesion. In order to facilitate an off-line validation
as realistic as possible, we also present a method for augmenting simulated virtual bronchoscopies with the appearance of intra-operative videos. Experiments performed on augmented and intra-operative videos, prove that our algorithm can be speeded up for an on-line implementation in the operating room. |
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October 2019 |
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Thesis |
Ph.D. thesis |
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Publisher |
Ediciones Graficas Rey |
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Editor |
Debora Gil;Carles Sanchez |
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978-84-121011-0-2 |
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Notes |
IAM; 600.139; 600.145 |
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no |
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Call Number |
Admin @ si @ Est2019 |
Serial |
3392 |
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Author |
Debora Gil; Oriol Ramos Terrades; Raquel Perez |
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Title |
Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution |
Type |
Book Chapter |
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Year |
2021 |
Publication |
Extended Abstracts GEOMVAP 2019, Trends in Mathematics 15 |
Abbreviated Journal |
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Volume |
15 |
Issue |
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Pages |
89–93 |
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Abstract |
Abnormalities in radiomic measures correlate to genomic alterations prone to alter the outcome of personalized anti-cancer treatments. TOPiomics is a new method for the early detection of variations in tumor imaging phenotype from a topological structure in multi-view radiomic spaces. |
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Springer Nature |
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IAM; DAG; 600.120; 600.145; 600.139 |
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no |
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Call Number |
Admin @ si @ GRP2021 |
Serial |
3594 |
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Author |
Jose Elias Yauri |
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Title |
Deep Learning Based Data Fusion Approaches for the Assessment of Cognitive States on EEG Signals |
Type |
Book Whole |
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Year |
2023 |
Publication |
PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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For millennia, the study of the couple brain-mind has fascinated the humanity in order to understand the complex nature of cognitive states. A cognitive state is the state of the mind at a specific time and involves cognition activities to acquire and process information for making a decision, solving a problem, or achieving a goal.
While normal cognitive states assist in the successful accomplishment of tasks; on the contrary, abnormal states of the mind can lead to task failures due to a reduced cognition capability. In this thesis, we focus on the assessment of cognitive states by means of the analysis of ElectroEncephaloGrams (EEG) signals using deep learning methods. EEG records the electrical activity of the brain using a set of electrodes placed on the scalp that output a set of spatiotemporal signals that are expected to be correlated to a specific mental process.
From the point of view of artificial intelligence, any method for the assessment of cognitive states using EEG signals as input should face several challenges. On the one hand, one should determine which is the most suitable approach for the optimal combination of the multiple signals recorded by EEG electrodes. On the other hand, one should have a protocol for the collection of good quality unambiguous annotated data, and an experimental design for the assessment of the generalization and transfer of models. In order to tackle them, first, we propose several convolutional neural architectures to perform data fusion of the signals recorded by EEG electrodes, at raw signal and feature levels. Four channel fusion methods, easy to incorporate into any neural network architecture, are proposed and assessed. Second, we present a method to create an unambiguous dataset for the prediction of cognitive mental workload using serious games and an Airbus-320 flight simulator. Third, we present a validation protocol that takes into account the levels of generalization of models based on the source and amount of test data.
Finally, the approaches for the assessment of cognitive states are applied to two use cases of high social impact: the assessment of mental workload for personalized support systems in the cockpit and the detection of epileptic seizures. The results obtained from the first use case show the feasibility of task transfer of models trained to detect workload in serious games to real flight scenarios. The results from the second use case show the generalization capability of our EEG channel fusion methods at k-fold cross-validation, patient-specific, and population levels. |
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Thesis |
Ph.D. thesis |
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Publisher |
IMPRIMA |
Place of Publication |
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Editor |
Aura Hernandez;Debora Gil |
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Notes |
IAM |
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no |
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Call Number |
Admin @ si @ Yau2023 |
Serial |
3962 |
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Author |
F.Guirado; Ana Ripoll; C.Roig; Aura Hernandez-Sabate; Emilio Luque |
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Title |
Exploiting Throughput for Pipeline Execution in Streaming Image Processing Applications |
Type |
Book Chapter |
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Year |
2006 |
Publication |
Euro-Par 2006 Parallel Processing |
Abbreviated Journal |
LNCS |
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Volume |
4128 |
Issue |
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Pages |
1095-1105 |
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Keywords |
12th International Euro–Par Conference |
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Abstract |
There is a large range of image processing applications that act on an input sequence of image frames that are continuously received. Throughput is a key performance measure to be optimized when execu- ting them. In this paper we propose a new task replication methodology for optimizing throughput for an image processing application in the field of medicine. The results show that by applying the proposed methodo- logy we are able to achieve the desired throughput in all cases, in such a way that the input frames can be processed at any given rate. |
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Springer-Verlag Berlin Heidelberg |
Place of Publication |
Dresden, Germany (European Union) |
Editor |
UAB; W, E.N.; et al. |
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Series Title |
Lecture Notes In Computer Science |
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Euro–Par |
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Notes |
IAM |
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no |
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Call Number |
IAM @ iam @ GRR2006a |
Serial |
1542 |
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Author |
Carles Sanchez;F. Javier Sanchez; Antoni Rosell; Debora Gil |
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Title |
An illumination model of the trachea appearance in videobronchoscopy images |
Type |
Book Chapter |
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Year |
2012 |
Publication |
Image Analysis and Recognition |
Abbreviated Journal |
LNCS |
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Volume |
7325 |
Issue |
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Pages |
313-320 |
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Keywords |
Bronchoscopy, tracheal ring, stenosis assesment, trachea appearance model, segmentation |
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Abstract |
Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways. This imaging modality provides realistic images and allows non-invasive minimal intervention procedures. Tracheal procedures are routinary interventions that require assessment of the percentage of obstructed pathway for injury (stenosis) detection. Visual assessment in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error.
This paper introduces an automatic method for the estimation of steneosed trachea percentage reduction in videobronchoscopic images. We look for tracheal rings , whose deformation determines the degree of obstruction. For ring extraction , we present a ring detector based on an illumination and appearance model. This model allows us to parametrise the ring detection. Finally, we can infer optimal estimation parameters for any video resolution. |
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Address |
Aveiro, Portugal |
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Publisher |
Springer Berlin Heidelberg |
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Lecture Notes in Computer Science |
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LNCS |
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ISSN |
0302-9743 |
ISBN |
978-3-642-31297-7 |
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Area |
800 |
Expedition |
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Conference |
ICIAR |
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Notes |
MV;IAM |
Approved |
no |
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Call Number |
IAM @ iam @ SSR2012 |
Serial |
1898 |
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Author |
Debora Gil; F. Javier Sanchez; Gloria Fernandez Esparrach; Jorge Bernal |
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Title |
3D Stable Spatio-temporal Polyp Localization in Colonoscopy Videos |
Type |
Book Chapter |
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Year |
2015 |
Publication |
Computer-Assisted and Robotic Endoscopy. Revised selected papers of Second International Workshop, CARE 2015, Held in Conjunction with MICCAI 2015 |
Abbreviated Journal |
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Volume |
9515 |
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Pages |
140-152 |
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Keywords |
Colonoscopy, Polyp Detection, Polyp Localization, Region Extraction, Watersheds |
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Abstract |
Computational intelligent systems could reduce polyp miss rate in colonoscopy for colon cancer diagnosis and, thus, increase the efficiency of the procedure. One of the main problems of existing polyp localization methods is a lack of spatio-temporal stability in their response. We propose to explore the response of a given polyp localization across temporal windows in order to select
those image regions presenting the highest stable spatio-temporal response.
Spatio-temporal stability is achieved by extracting 3D watershed regions on the
temporal window. Stability in localization response is statistically determined by analysis of the variance of the output of the localization method inside each 3D region. We have explored the benefits of considering spatio-temporal stability in two different tasks: polyp localization and polyp detection. Experimental results indicate an average improvement of 21:5% in polyp localization and 43:78% in polyp detection. |
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LNCS |
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CARE |
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Notes |
IAM; MV; 600.075 |
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no |
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Call Number |
Admin @ si @ GSF2015 |
Serial |
2733 |
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Author |
Debora Gil; Petia Radeva |
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Title |
Curvature Vector Flow to Assure Convergent Deformable Models for Shape Modelling |
Type |
Book Chapter |
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Year |
2003 |
Publication |
Energy Minimization Methods In Computer Vision And Pattern Recognition |
Abbreviated Journal |
LNCS |
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Volume |
2683 |
Issue |
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Pages |
357-372 |
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Keywords |
Initial condition; Convex shape; Non convex analysis; Increase; Segmentation; Gradient; Standard; Standards; Concave shape; Flow models; Tracking; Edge detection; Curvature |
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Abstract |
Poor convergence to concave shapes is a main limitation of snakes as a standard segmentation and shape modelling technique. The gradient of the external energy of the snake represents a force that pushes the snake into concave regions, as its internal energy increases when new inexion points are created. In spite of the improvement of the external energy by the gradient vector ow technique, highly non convex shapes can not be obtained, yet. In the present paper, we develop a new external energy based on the geometry of the curve to be modelled. By tracking back the deformation of a curve that evolves by minimum curvature ow, we construct a distance map that encapsulates the natural way of adapting to non convex shapes. The gradient of this map, which we call curvature vector ow (CVF), is capable of attracting a snake towards any contour, whatever its geometry. Our experiments show that, any initial snake condition converges to the curve to be modelled in optimal time. |
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Publisher |
Springer, Berlin |
Place of Publication |
Lisbon, PORTUGAL |
Editor |
Springer, B. |
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Series Title |
Lecture Notes in Computer Science |
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LNCS |
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0302-9743 |
ISBN |
3-540-40498-8 |
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Notes |
IAM;MILAB |
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no |
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Call Number |
IAM @ iam @ GIR2003b |
Serial |
1535 |
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Author |
David Roche; Debora Gil; Jesus Giraldo |
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Title |
Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? |
Type |
Book Chapter |
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Year |
2014 |
Publication |
G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology |
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Volume |
796 |
Issue |
3 |
Pages |
159-181 |
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Keywords |
β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model |
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Abstract |
Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists. |
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Springer Netherlands |
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ISSN |
0065-2598 |
ISBN |
978-94-007-7422-3 |
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Notes |
IAM; 600.075 |
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Call Number |
IAM @ iam @ RGG2014 |
Serial |
2197 |
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Author |
Josep Llados; Jaime Lopez-Krahe; Enric Marti |
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Title |
A system to understand hand-drawn floor plans using subgraph isomorphism and Hough transform |
Type |
Book Chapter |
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Year |
1997 |
Publication |
Machine Vision and Applications |
Abbreviated Journal |
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Volume |
10 |
Issue |
3 |
Pages |
150-158 |
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Keywords |
Line drawings – Hough transform – Graph matching – CAD systems – Graphics recognition |
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Abstract |
Presently, man-machine interface development is a widespread research activity. A system to understand hand drawn architectural drawings in a CAD environment is presented in this paper. To understand a document, we have to identify its building elements and their structural properties. An attributed graph structure is chosen as a symbolic representation of the input document and the patterns to recognize in it. An inexact subgraph isomorphism procedure using relaxation labeling techniques is performed. In this paper we focus on how to speed up the matching. There is a building element, the walls, characterized by a hatching pattern. Using a straight line Hough transform (SLHT)-based method, we recognize this pattern, characterized by parallel straight lines, and remove from the input graph the edges belonging to this pattern. The isomorphism is then applied to the remainder of the input graph. When all the building elements have been recognized, the document is redrawn, correcting the inaccurate strokes obtained from a hand-drawn input. |
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DAG;IAM |
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Call Number |
IAM @ iam @ LLM1997a |
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1566 |
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Author |
Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru; Miguel Angel Gonzalez Ballester |
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Title |
Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs |
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Book Chapter |
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2012 |
Publication |
Workshop on Computational and Clinical Applications in Abdominal Imaging |
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7029 |
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223–230 |
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medial manifolds, abdomen. |
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Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D
objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial
manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our
method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs,
exploring the use of medial manifolds for the representation of multi-organ relations. |
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Toronto; Canada; |
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Springer Link |
Place of Publication |
Berlin |
Editor |
H. Yoshida et al |
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Language |
English |
Summary Language |
English |
Original Title |
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Lecture Notes in Computer Science |
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LNCS |
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0302-9743 |
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978-3-642-28556-1 |
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ABDI |
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IAM;MV |
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Call Number |
IAM @ iam @ VGB2012 |
Serial |
1834 |
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