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Author Juan Borrego-Carazo; Carles Sanchez; David Castells; Jordi Carrabina; Debora Gil edit  openurl
  Title A benchmark for the evaluation of computational methods for bronchoscopic navigation Type Journal Article
  Year 2022 Publication International Journal of Computer Assisted Radiology and Surgery Abbreviated Journal IJCARS  
  Volume (down) 17 Issue 1 Pages  
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  Notes IAM Approved no  
  Call Number Admin @ si @ BSC2022 Serial 3832  
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Author Antoni Rosell; Sonia Baeza; S. Garcia-Reina; JL. Mate; Ignasi Guasch; I. Nogueira; I. Garcia-Olive; Guillermo Torres; Carles Sanchez; Debora Gil edit  url
openurl 
  Title EP01.05-001 Radiomics to Increase the Effectiveness of Lung Cancer Screening Programs. Radiolung Preliminary Results Type Journal Article
  Year 2022 Publication Journal of Thoracic Oncology Abbreviated Journal JTO  
  Volume (down) 17 Issue 9 Pages S182  
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  Notes IAM Approved no  
  Call Number Admin @ si @ RBG2022b Serial 3834  
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Author Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Francesca Vidal; Zaida Sarrate edit   pdf
isbn  openurl
  Title Noves perspectives en l estudi de la territorialitat cromosomica de cel·lules germinals masculines: estudis tridimensionals Type Journal
  Year 2017 Publication Biologia de la Reproduccio Abbreviated Journal JBR  
  Volume (down) 15 Issue Pages 73-78  
  Keywords  
  Abstract In somatic cells, chromosomes occupy specific nuclear regions called chromosome territories which are involved in the
maintenance and regulation of the genome. Preliminary data in male germ cells also suggest the importance of chromosome
territoriality in cell functionality. Nevertheless, the specific characteristics of testicular tissue (presence of different
cell types with different morphological characteristics, in different stages of development and with different ploidy)
makes difficult to achieve conclusive results. In this study we have developed a methodology to approach the threedimensional
study of all chromosome territories in male germ cells from C57BL/6J mice (Mus musculus). The method
includes the following steps: i) Optimized cell fixation to obtain an optimal preservation of the three-dimensionality cell
morphology, ii) Chromosome identification by FISH (Chromoprobe Multiprobe® OctoChrome™ Murine System; Cytocell)
and confocal microscopy (TCS-SP5, Leica Microsystems), iii) Cell type identification by immunofluorescence
iv) Image analysis using Matlab scripts, v) Numerical data extraction related to chromosome features, chromosome
radial position and chromosome relative position. This methodology allows the unequivocally identification and the
analysis of the chromosome territories of all spermatogenic stages. Results will provide information about the features
that determine chromosomal position, preferred associations between chromosomes, and the relationship between chromosome
positioning and genome regulation.
 
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  ISSN ISBN 978-84-697-3767-5 Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 600.145 Approved no  
  Call Number Admin @ si @ SBG2017c Serial 2961  
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Author Guillermo Torres; Debora Gil edit  openurl
  Title A multi-shape loss function with adaptive class balancing for the segmentation of lung structures Type Journal Article
  Year 2020 Publication International Journal of Computer Assisted Radiology and Surgery Abbreviated Journal IJCAR  
  Volume (down) 15 Issue 1 Pages S154-55  
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  Notes IAM Approved no  
  Call Number Admin @ si @ ToG2020 Serial 3590  
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Author Debora Gil; Oriol Ramos Terrades; Raquel Perez edit  doi
openurl 
  Title Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution Type Book Chapter
  Year 2021 Publication Extended Abstracts GEOMVAP 2019, Trends in Mathematics 15 Abbreviated Journal  
  Volume (down) 15 Issue Pages 89–93  
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  Abstract Abnormalities in radiomic measures correlate to genomic alterations prone to alter the outcome of personalized anti-cancer treatments. TOPiomics is a new method for the early detection of variations in tumor imaging phenotype from a topological structure in multi-view radiomic spaces.  
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  Publisher Springer Nature Place of Publication Editor  
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  Notes IAM; DAG; 600.120; 600.145; 600.139 Approved no  
  Call Number Admin @ si @ GRP2021 Serial 3594  
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Author Debora Gil; Ruth Aris; Agnes Borras; Esmitt Ramirez; Rafael Sebastian; Mariano Vazquez edit   pdf
doi  openurl
  Title Influence of fiber connectivity in simulations of cardiac biomechanics Type Journal Article
  Year 2019 Publication International Journal of Computer Assisted Radiology and Surgery Abbreviated Journal IJCAR  
  Volume (down) 14 Issue 1 Pages 63–72  
  Keywords Cardiac electromechanical simulations; Diffusion tensor imaging; Fiber connectivity  
  Abstract PURPOSE:
Personalized computational simulations of the heart could open up new improved approaches to diagnosis and surgery assistance systems. While it is fully recognized that myocardial fiber orientation is central for the construction of realistic computational models of cardiac electromechanics, the role of its overall architecture and connectivity remains unclear. Morphological studies show that the distribution of cardiac muscular fibers at the basal ring connects epicardium and endocardium. However, computational models simplify their distribution and disregard the basal loop. This work explores the influence in computational simulations of fiber distribution at different short-axis cuts.

METHODS:
We have used a highly parallelized computational solver to test different fiber models of ventricular muscular connectivity. We have considered two rule-based mathematical models and an own-designed method preserving basal connectivity as observed in experimental data. Simulated cardiac functional scores (rotation, torsion and longitudinal shortening) were compared to experimental healthy ranges using generalized models (rotation) and Mahalanobis distances (shortening, torsion).

RESULTS:
The probability of rotation was significantly lower for ruled-based models [95% CI (0.13, 0.20)] in comparison with experimental data [95% CI (0.23, 0.31)]. The Mahalanobis distance for experimental data was in the edge of the region enclosing 99% of the healthy population.

CONCLUSIONS:
Cardiac electromechanical simulations of the heart with fibers extracted from experimental data produce functional scores closer to healthy ranges than rule-based models disregarding architecture connectivity.
 
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  Notes IAM; 600.096; 601.323; 600.139; 600.145 Approved no  
  Call Number Admin @ si @ GAB2019a Serial 3133  
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Author Debora Gil; Carles Sanchez; Agnes Borras; Marta Diez-Ferrer; Antoni Rosell edit   pdf
url  doi
openurl 
  Title Segmentation of Distal Airways using Structural Analysis Type Journal Article
  Year 2019 Publication PloS one Abbreviated Journal Plos  
  Volume (down) 14 Issue 12 Pages  
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  Abstract Segmentation of airways in Computed Tomography (CT) scans is a must for accurate support of diagnosis and intervention of many pulmonary disorders. In particular, lung cancer diagnosis would benefit from segmentations reaching most distal airways. We present a method that combines descriptors of bronchi local appearance and graph global structural analysis to fine-tune thresholds on the descriptors adapted for each bronchial level. We have compared our method to the top performers of the EXACT09 challenge and to a commercial software for biopsy planning evaluated in an own-collected data-base of high resolution CT scans acquired under different breathing conditions. Results on EXACT09 data show that our method provides a high leakage reduction with minimum loss in airway detection. Results on our data-base show the reliability across varying breathing conditions and a competitive performance for biopsy planning compared to a commercial solution.  
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  Notes IAM; 600.139; 600.145 Approved no  
  Call Number Admin @ si @ GSB2019 Serial 3357  
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Author Jose Elias Yauri; M. Lagos; H. Vega-Huerta; P. de-la-Cruz; G.L.E Maquen-Niño; E. Condor-Tinoco edit  doi
openurl 
  Title Detection of Epileptic Seizures Based-on Channel Fusion and Transformer Network in EEG Recordings Type Journal Article
  Year 2023 Publication International Journal of Advanced Computer Science and Applications Abbreviated Journal IJACSA  
  Volume (down) 14 Issue 5 Pages 1067-1074  
  Keywords Epilepsy; epilepsy detection; EEG; EEG channel fusion; convolutional neural network; self-attention  
  Abstract According to the World Health Organization, epilepsy affects more than 50 million people in the world, and specifically, 80% of them live in developing countries. Therefore, epilepsy has become among the major public issue for many governments and deserves to be engaged. Epilepsy is characterized by uncontrollable seizures in the subject due to a sudden abnormal functionality of the brain. Recurrence of epilepsy attacks change people’s lives and interferes with their daily activities. Although epilepsy has no cure, it could be mitigated with an appropriated diagnosis and medication. Usually, epilepsy diagnosis is based on the analysis of an electroencephalogram (EEG) of the patient. However, the process of searching for seizure patterns in a multichannel EEG recording is a visual demanding and time consuming task, even for experienced neurologists. Despite the recent progress in automatic recognition of epilepsy, the multichannel nature of EEG recordings still challenges current methods. In this work, a new method to detect epilepsy in multichannel EEG recordings is proposed. First, the method uses convolutions to perform channel fusion, and next, a self-attention network extracts temporal features to classify between interictal and ictal epilepsy states. The method was validated in the public CHB-MIT dataset using the k-fold cross-validation and achieved 99.74% of specificity and 99.15% of sensitivity, surpassing current approaches.  
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  Notes IAM Approved no  
  Call Number Admin @ si @ Serial 3856  
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Author Debora Gil; Petia Radeva edit   pdf
doi  openurl
  Title A Regularized Curvature Flow Designed for a Selective Shape Restoration Type Journal Article
  Year 2004 Publication IEEE Transactions on Image Processing Abbreviated Journal  
  Volume (down) 13 Issue Pages 1444–1458  
  Keywords Geometric flows, nonlinear filtering, shape recovery.  
  Abstract Among all filtering techniques, those based exclu- sively on image level sets (geometric flows) have proven to be the less sensitive to the nature of noise and the most contrast preserving. A common feature to existent curvature flows is that they penalize high curvature, regardless of the curve regularity. This constitutes a major drawback since curvature extreme values are standard descriptors of the contour geometry. We argue that an operator designed with shape recovery purposes should include a term penalizing irregularity in the curvature rather than its magnitude. To this purpose, we present a novel geometric flow that includes a function that measures the degree of local irregularity present in the curve. A main advantage is that it achieves non-trivial steady states representing a smooth model of level curves in a noisy image. Performance of our approach is compared to classical filtering techniques in terms of quality in the restored image/shape and asymptotic behavior. We empirically prove that our approach is the technique that achieves the best compromise between image quality and evolution stabilization.  
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  Notes IAM;MILAB Approved no  
  Call Number BCNPCL @ bcnpcl @ GiR2004b Serial 491  
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Author Misael Rosales; Petia Radeva;Oriol Rodriguez-Leon; Debora Gil edit   pdf
doi  openurl
  Title Modelling of image-catheter motion for 3-D IVUS Type Journal Article
  Year 2009 Publication Medical image analysis Abbreviated Journal MIA  
  Volume (down) 13 Issue 1 Pages 91-104  
  Keywords Intravascular ultrasound (IVUS); Motion estimation; Motion decomposition; Fourier  
  Abstract Three-dimensional intravascular ultrasound (IVUS) allows to visualize and obtain volumetric measurements of coronary lesions through an exploration of the cross sections and longitudinal views of arteries. However, the visualization and subsequent morpho-geometric measurements in IVUS longitudinal cuts are subject to distortion caused by periodic image/vessel motion around the IVUS catheter. Usually, to overcome the image motion artifact ECG-gating and image-gated approaches are proposed, leading to slowing the pullback acquisition or disregarding part of IVUS data. In this paper, we argue that the image motion is due to 3-D vessel geometry as well as cardiac dynamics, and propose a dynamic model based on the tracking of an elliptical vessel approximation to recover the rigid transformation and align IVUS images without loosing any IVUS data. We report an extensive validation with synthetic simulated data and in vivo IVUS sequences of 30 patients achieving an average reduction of the image artifact of 97% in synthetic data and 79% in real-data. Our study shows that IVUS alignment improves longitudinal analysis of the IVUS data and is a necessary step towards accurate reconstruction and volumetric measurements of 3-D IVUS.  
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  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RRR2009 Serial 1646  
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