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Author Jaume Garcia edit   pdf
openurl 
  Title Generalized Active Shape Models Applied to Cardiac Function Analysis Type Report
  Year 2004 Publication CVC Technical Report Abbreviated Journal  
  Volume Issue 78 Pages  
  Keywords Cardiac Analysis; Deformable Models; Active Contour Models; Active Shape Models; Tagged MRI; HARP; Contrast Echocardiography.  
  Abstract Medical imaging is very useful in the assessment and treatment of many diseases. To deal with the great amount of data provided by imaging scanners and extract quantitative information that physicians can interpret, many analysis algorithms have been developed. Any process of analysis always consists of a first step of segmenting some particular structure. In medical imaging, structures are not always well defined and suffer from noise artifacts thus, ordinary segmentation methods are not well suited. The ones that seem to give better results are those based on deformable models. Nevertheless, despite their capability of mixing image features together with smoothness constraints that may compensate for image irregularities, these are naturally local methods, i. e., each node of the active contour evolve taking into account information about its neighbors and some other weak constraints about flexibility and smoothness, but not about the global shape that they should find. Due to the fact that structures to be segmented are the same for all cases but with some inter and intra-patient variation, the incorporation of a priori knowledge about shape in the segmentation method will provide robustness to it. Active Shape Models is an algorithm based on the creation of a shape model called Point Distribution Model. It performs a segmentation using only shapes similar than those previously learned from a training set that capture most of the variation presented by the structure. This algorithm works by updating shape nodes along a normal segment which often can be too restrictive. For this reason we propose a generalization of this algorithm that we call Generalized Active Shape Models and fully integrates the a priori knowledge given by the Point Distribution Model with deformable models or any other appropriate segmentation method. Two different applications to cardiac imaging of this generalized method are developed and promising results are shown.  
  Address CVC (UAB)  
  Corporate Author Thesis Master's thesis  
  Publisher Place of Publication Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ Gar2004 Serial 1513  
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Author Jaume Garcia; Albert Andaluz; Debora Gil; Francesc Carreras edit   pdf
url  doi
isbn  openurl
  Title Decoupled External Forces in a Predictor-Corrector Segmentation Scheme for LV Contours in Tagged MR Images Type Conference Article
  Year 2010 Publication 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society Abbreviated Journal  
  Volume Issue Pages 4805-4808  
  Keywords  
  Abstract Computation of functional regional scores requires proper identification of LV contours. On one hand, manual segmentation is robust, but it is time consuming and requires high expertise. On the other hand, the tag pattern in TMR sequences is a problem for automatic segmentation of LV boundaries. We propose a segmentation method based on a predictorcorrector (Active Contours – Shape Models) scheme. Special stress is put in the definition of the AC external forces. First, we introduce a semantic description of the LV that discriminates myocardial tissue by using texture and motion descriptors. Second, in order to ensure convergence regardless of the initial contour, the external energy is decoupled according to the orientation of the edges in the image potential. We have validated the model in terms of error in segmented contours and accuracy of regional clinical scores.  
  Address Buenos Aires (Argentina)  
  Corporate Author IEEE EMB Thesis  
  Publisher Place of Publication Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1557-170X ISBN 978-1-4244-4123-5 Medium  
  Area Expedition Conference EMBC  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GAG2010 Serial 1514  
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Author Jaume Garcia; Debora Gil; Aura Hernandez-Sabate edit   pdf
doi  openurl
  Title Endowing Canonical Geometries to Cardiac Structures Type Book Chapter
  Year 2010 Publication Statistical Atlases And Computational Models Of The Heart Abbreviated Journal  
  Volume 6364 Issue Pages 124-133  
  Keywords  
  Abstract International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view.
 
  Address  
  Corporate Author Thesis  
  Publisher Springer Berlin / Heidelberg Place of Publication Editor Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A.  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGH2010b Serial 1515  
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Author M.Gomez; Josefina Mauri; Eduard Fernandez-Nofrerias; Oriol Rodriguez-Leon; Carme Julia; Debora Gil; Petia Radeva edit  openurl
  Title Reconstrucción de un modelo espacio-temporal de la luz del vaso a partir de secuencias de ecografía intracoronaria Type Conference Article
  Year 2002 Publication XXXVIII Congreso Nacional de la Sociedad Española de Cardiología. Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;ADAS;MILAB Approved no  
  Call Number IAM @ iam @ GMF2002d Serial 1516  
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Author Debora Gil edit   pdf
isbn  openurl
  Title Geometric Differential Operators for Shape Modelling Type Book Whole
  Year 2004 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Medical imaging feeds research in many computer vision and image processing fields: image filtering, segmentation, shape recovery, registration, retrieval and pattern matching. Because of their low contrast changes and large variety of artifacts and noise, medical imaging processing techniques relying on an analysis of the geometry of image level sets rather than on intensity values result in more robust treatment. From the starting point of treatment of intravascular images, this PhD thesis ad- dresses the design of differential image operators based on geometric principles for a robust shape modelling and restoration. Among all fields applying shape recovery, we approach filtering and segmentation of image objects. For a successful use in real images, the segmentation process should go through three stages: noise removing, shape modelling and shape recovery. This PhD addresses all three topics, but for the sake of algorithms as automated as possible, techniques for image processing will be designed to satisfy three main principles: a) convergence of the iterative schemes to non-trivial states avoiding image degeneration to a constant image and representing smooth models of the originals; b) smooth asymptotic behav- ior ensuring stabilization of the iterative process; c) fixed parameter values ensuring equal (domain free) performance of the algorithms whatever initial images/shapes. Our geometric approach to the generic equations that model the different processes approached enables defining techniques satisfying all the former requirements. First, we introduce a new curvature-based geometric flow for image filtering achieving a good compromise between noise removing and resemblance to original images. Sec- ond, we describe a new family of diffusion operators that restrict their scope to image level curves and serve to restore smooth closed models from unconnected sets of points. Finally, we design a regularization of snake (distance) maps that ensures its smooth convergence towards any closed shape. Experiments show that performance of the techniques proposed overpasses that of state-of-the-art algorithms.  
  Address  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Barcelona (Spain) Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 84-933652-0-3 Medium prit  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ GIL2004 Serial 1517  
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Author Debora Gil edit  openurl
  Title Regularized Curvature Flow Type Report
  Year 2002 Publication CVC Technical Report Abbreviated Journal  
  Volume Issue 63 Pages  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Computer Vision Centre Place of Publication Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ Gil2002 Serial 1518  
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Author Debora Gil; Jose Maria-Carazo; Roberto Marabini edit   pdf
doi  openurl
  Title On the nature of 2D crystal unbending Type Journal Article
  Year 2006 Publication Journal of Structural Biology Abbreviated Journal  
  Volume 156 Issue 3 Pages 546-555  
  Keywords Electron microscopy  
  Abstract Crystal unbending, the process that aims to recover a perfect crystal from experimental data, is one of the more important steps in electron crystallography image processing. The unbending process involves three steps: estimation of the unit cell displacements from their ideal positions, extension of the deformation field to the whole image and transformation of the image in order to recover an ideal crystal. In this work, we present a systematic analysis of the second step oriented to address two issues. First, whether the unit cells remain undistorted and only the distance between them should be changed (rigid case) or should be modified with the same deformation suffered by the whole crystal (elastic case). Second, the performance of different extension algorithms (interpolation versus approximation) is explored. Our experiments show that there is no difference between elastic and rigid cases or among the extension algorithms. This implies that the deformation fields are constant over large areas. Furthermore, our results indicate that the main source of error is the transformation of the crystal image.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1047-8477 ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ GCM2006 Serial 1519  
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Author Debora Gil; Jaume Garcia; Ruth Aris; Guillaume Houzeaux; Manuel Vazquez edit   pdf
openurl 
  Title A Riemmanian approach to cardiac fiber architecture modelling Type Conference Article
  Year 2009 Publication 1st International Conference on Mathematical & Computational Biomedical Engineering Abbreviated Journal  
  Volume Issue Pages 59-62  
  Keywords cardiac fiber architecture; diffusion tensor magnetic resonance imaging; differential (Rie- mannian) geometry.  
  Abstract There is general consensus that myocardial fiber architecture should be modelled in order to fully understand the electromechanical properties of the Left Ventricle (LV). Diffusion Tensor magnetic resonance Imaging (DTI) is the reference image modality for rapid measurement of fiber orientations by means of the tensor principal eigenvectors. In this work, we present a mathematical framework for across subject comparison of the local geometry of the LV anatomy including the fiber architecture from the statistical analysis of DTI studies. We use concepts of differential geometry for defining a parametric domain suitable for statistical analysis of a low number of samples. We use Riemannian metrics to define a consistent computation of DTI principal eigenvector modes of variation. Our framework has been applied to build an atlas of the LV fiber architecture from 7 DTI normal canine hearts.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Swansea (UK) Editor Nithiarasu, R.L.R.V.L.  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference CMBE  
  Notes IAM Approved no  
  Call Number IAM @ iam @ FGA2009 Serial 1520  
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Author Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux edit   pdf
url  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
  Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance.  
  Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Venezia (Italia) Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN B-31470-08 ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGV2008c Serial 1521  
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Author Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti edit   pdf
url  doi
openurl 
  Title Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy Type Conference Article
  Year 2010 Publication 8th Medical Imaging Abbreviated Journal  
  Volume 7623 Issue 762304 Pages 304  
  Keywords  
  Abstract Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature.  
  Address  
  Corporate Author Thesis  
  Publisher SPIE Place of Publication Editor  
  Language (up) Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference SPIE  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGH2010a Serial 1522  
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