toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
  Records Links
Author Mireia Sole; Joan Blanco; Debora Gil; Gothami Fonseka; Richard Frodsham; Oliver Valero; Francesca Vidal; Zaida Sarrate edit   pdf
openurl 
  Title Is there a pattern of Chromosome territoriality along mice spermatogenesis? Type Conference Article
  Year 2017 Publication 3rd Spanish MeioNet Meeting Abstract Book Abbreviated Journal  
  Volume Issue Pages 55-56  
  Keywords  
  Abstract  
  Address Miraflores de la Sierra; Madrid; June 2017  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference MEIONET  
  Notes IAM; 600.096; 600.145 Approved no  
  Call Number (up) Admin @ si @ Serial 2958  
Permanent link to this record
 

 
Author Francesco Brughi; Debora Gil; Llorenç Badiella; Eva Jove Casabella; Oriol Ramos Terrades edit   pdf
doi  isbn
openurl 
  Title Exploring the impact of inter-query variability on the performance of retrieval systems Type Conference Article
  Year 2014 Publication 11th International Conference on Image Analysis and Recognition Abbreviated Journal  
  Volume 8814 Issue Pages 413–420  
  Keywords  
  Abstract This paper introduces a framework for evaluating the performance of information retrieval systems. Current evaluation metrics provide an average score that does not consider performance variability across the query set. In this manner, conclusions lack of any statistical significance, yielding poor inference to cases outside the query set and possibly unfair comparisons. We propose to apply statistical methods in order to obtain a more informative measure for problems in which different query classes can be identified. In this context, we assess the performance variability on two levels: overall variability across the whole query set and specific query class-related variability. To this end, we estimate confidence bands for precision-recall curves, and we apply ANOVA in order to assess the significance of the performance across different query classes.  
  Address Algarve; Portugal; October 2014  
  Corporate Author Thesis  
  Publisher Springer International Publishing Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-319-11757-7 Medium  
  Area Expedition Conference ICIAR  
  Notes IAM; DAG; 600.060; 600.061; 600.077; 600.075 Approved no  
  Call Number (up) Admin @ si @ BGB2014 Serial 2559  
Permanent link to this record
 

 
Author Jorge Bernal; Debora Gil; Carles Sanchez; F. Javier Sanchez edit   pdf
doi  isbn
openurl 
  Title Discarding Non Informative Regions for Efficient Colonoscopy Image Analysis Type Conference Article
  Year 2014 Publication 1st MICCAI Workshop on Computer-Assisted and Robotic Endoscopy Abbreviated Journal  
  Volume 8899 Issue Pages 1-10  
  Keywords Image Segmentation; Polyps, Colonoscopy; Valley Information; Energy Maps  
  Abstract In this paper we present a novel polyp region segmentation method for colonoscopy videos. Our method uses valley information associated to polyp boundaries in order to provide an initial segmentation. This first segmentation is refined to eliminate boundary discontinuities caused by image artifacts or other elements of the scene. Experimental results over a publicly annotated database show that our method outperforms both general and specific segmentation methods by providing more accurate regions rich in polyp content. We also prove how image preprocessing is needed to improve final polyp region segmentation.  
  Address Boston; USA; September 2014  
  Corporate Author Thesis  
  Publisher Springer International Publishing Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title LNCS  
  Series Volume Series Issue Edition  
  ISSN 0302-9743 ISBN 978-3-319-13409-3 Medium  
  Area Expedition Conference CARE  
  Notes MV; IAM; 600.044; 600.047; 600.060; 600.075 Approved no  
  Call Number (up) Admin @ si @ BGS2014b Serial 2503  
Permanent link to this record
 

 
Author Angels Barbera; Ruth Marginet Flinch; Montserrat Martin; Jose L Mate; Albert Oriol; Fina Martinez-Soler; Tomas Santalucia; Pedro L. Fernandez edit  url
doi  openurl
  Title The Immunohistochemical Expression of Programmed Death Ligand 1 Type Journal Article
  Year 2020 Publication Applied Immunohistochemistry & Molecular Morphology Abbreviated Journal AIMM  
  Volume Issue Pages  
  Keywords  
  Abstract Humanized antibodies targeting programmed death receptor 1 (PD-1) or its ligand (PD-L1) have been approved for the treatment of different cancers. Some of these antibodies show a correlation between the tissue expression of PD-L1 and response. Evaluation of PD-L1 expression presents multiple challenges, but some preanalytical issues such as tissue fixation have been scarcely evaluated. With the hypothesis that immunohistochemical staining of PD-L1 may be impacted by the time of specimen fixation, we evaluated differences in its expression in tonsil samples exposed to predefined fixation times. Random nontumoral tonsillectomy specimens were blindly evaluated in tissue microarray slides after staining with SP142 and SP263 antibodies. With fixation times ranging from 12 to 72 hours, between 2.8% and 6.1% of the samples were considered to be suboptimally stained, with no differences between the 2 antibodies within these fixation times. A significantly higher proportion of samples exposed to a fixation time of 96 hours presented suboptimal immunostaining (15.6%, P<0.0001). In addition, suboptimally stained spots were 20.8% using SP142 and 10.4% using SP263 after 96 hours of fixation (P=0.046). In conclusion, the quality of staining for PD-L1 in tonsil samples decreased with overfixation of the specimen at times >72 hours. Samples exposed to formaldehyde for longer periods presented suboptimal results for both clones, but the SP142 antibody presented a significantly lower tolerance to formalin overexposure than SP263. These results indicate the relevance of a controlled preanalytical processing of samples and particularly the length of fixation of tumor specimens.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.139; 600.145 Approved no  
  Call Number (up) Admin @ si @ BMM2020 Serial 3470  
Permanent link to this record
 

 
Author Francesco Brughi edit  openurl
  Title Artistic Heritage Motive Retrieval: an Explorative Study Type Report
  Year 2013 Publication CVC Technical Report Abbreviated Journal  
  Volume 176 Issue Pages  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis Master's thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number (up) Admin @ si @ Bru2013 Serial 2410  
Permanent link to this record
 

 
Author Jorge Bernal; F. Javier Sanchez; Gloria Fernandez-Esparrach; Debora Gil; Cristina Rodriguez de Miguel; Fernando Vilariño edit   pdf
doi  openurl
  Title WM-DOVA Maps for Accurate Polyp Highlighting in Colonoscopy: Validation vs. Saliency Maps from Physicians Type Journal Article
  Year 2015 Publication Computerized Medical Imaging and Graphics Abbreviated Journal CMIG  
  Volume 43 Issue Pages 99-111  
  Keywords Polyp localization; Energy Maps; Colonoscopy; Saliency; Valley detection  
  Abstract We introduce in this paper a novel polyp localization method for colonoscopy videos. Our method is based on a model of appearance for polyps which defines polyp boundaries in terms of valley information. We propose the integration of valley information in a robust way fostering complete, concave and continuous boundaries typically associated to polyps. This integration is done by using a window of radial sectors which accumulate valley information to create WMDOVA1 energy maps related with the likelihood of polyp presence. We perform a double validation of our maps, which include the introduction of two new databases, including the first, up to our knowledge, fully annotated database with clinical metadata associated. First we assess that the highest value corresponds with the location of the polyp in the image. Second, we show that WM-DOVA energy maps can be comparable with saliency maps obtained from physicians' fixations obtained via an eye-tracker. Finally, we prove that our method outperforms state-of-the-art computational saliency results. Our method shows good performance, particularly for small polyps which are reported to be the main sources of polyp miss-rate, which indicates the potential applicability of our method in clinical practice.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0895-6111 ISBN Medium  
  Area Expedition Conference  
  Notes MV; IAM; 600.047; 600.060; 600.075 Approved no  
  Call Number (up) Admin @ si @ BSF2015 Serial 2609  
Permanent link to this record
 

 
Author Ester Conde; Susana Herandez; Rebeca Martinez; Barbara Angulo; Javier de Castro; Ana Collazo; Beatriz Jimenez; Alfonso Muriel; Jose Luis Mate; Teresa Moran; Ignacio Aranda; Bartomeu Massuti; Federico Rojo; Manuel Domine; Irene Sansano; Felipe Garcia; Enriqueta Felip; Nuria Mancheno; Oscar Juan; Julian Sanz; Jose Luis Gonzalez; Lidia Atienza; Esperanza Arriola; I. Abdulkader; J.Garcia; C. Camacho; D. Rodriguez; D. Teixido; N. Reguart; A.Gonzalez; M. Lazaro; MD. Lozano; J. Gomez; M. Lopez; L Pijuan; M Salido; E. Arriola; A. Company; A. Insa; I. Esteban; M. Saiz; E. Azkona; R. Alvarez; A. Artal; ML. Plaza; D. Aguiar; AB. Enguita, A. Benito; L. Paz; P. Garrido; F. Lopez edit  url
doi  openurl
  Title Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Patients with Non–Small Cell Lung Carcinoma: the ROSING Study Type Journal Article
  Year 2019 Publication Journal of Thoracic Oncology Abbreviated Journal  
  Volume 14 Issue 12 Pages 2120-2132  
  Keywords  
  Abstract Introduction
The ROS1 gene rearrangement has become an important biomarker in NSCLC. The College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology testing guidelines support the use of ROS1 immunohistochemistry (IHC) as a screening test, followed by confirmation with fluorescence in situ hybridization (FISH) or a molecular test in all positive results. We have evaluated a novel anti-ROS1 IHC antibody (SP384) in a large multicenter series to obtain real-world data.

Methods
A total of 43 ROS1 FISH–positive and 193 ROS1 FISH–negative NSCLC samples were studied. All specimens were screened by using two antibodies (clone D4D6 from Cell Signaling Technology and clone SP384 from Ventana Medical Systems), and the different interpretation criteria were compared with break-apart FISH (Vysis). FISH-positive samples were also analyzed with next-generation sequencing (Oncomine Dx Target Test Panel, Thermo Fisher Scientific).

Results
An H-score of 150 or higher or the presence of at least 70% of tumor cells with an intensity of staining of 2+ or higher by the SP384 clone was the optimal cutoff value (both with 93% sensitivity and 100% specificity). The D4D6 clone showed similar results, with an H-score of at least 100 (91% sensitivity and 100% specificity). ROS1 expression in normal lung was more frequent with use of the SP384 clone (p < 0.0001). The ezrin gene (EZR)-ROS1 variant was associated with membranous staining and an isolated green signal FISH pattern (p = 0.001 and p = 0.017, respectively).

Conclusions
The new SP384 ROS1 IHC clone showed excellent sensitivity without compromising specificity, so it is another excellent analytical option for the proposed testing algorithm.
 
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.139; 600.145 Approved no  
  Call Number (up) Admin @ si @ CHM2019 Serial 3471  
Permanent link to this record
 

 
Author Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso; Vanesa Vicens; Cubero Noelia; Rosa Lopez Lisbona; Carles Sanchez; Agnes Borras; Antoni Rosell edit  url
openurl 
  Title Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation Type Journal Article
  Year 2016 Publication Chest Journal Abbreviated Journal CHEST  
  Volume 150 Issue 4 Pages 1003A  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 600.075 Approved no  
  Call Number (up) Admin @ si @ DGC2016 Serial 3099  
Permanent link to this record
 

 
Author Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso edit  url
openurl 
  Title Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation Type Journal Article
  Year 2017 Publication Journal of Thoracic Oncology Abbreviated Journal JTO  
  Volume 12 Issue 1S Pages S596-S597  
  Keywords Thorax CT; diagnosis; Peripheral Pulmonary Nodule  
  Abstract A main weakness of virtual bronchoscopic navigation (VBN) is unsuccessful segmentation of distal branches approaching peripheral pulmonary nodules (PPN). CT scan acquisition protocol is pivotal for segmentation covering the utmost periphery. We hypothesize that application of continuous positive airway pressure (CPAP) during CT acquisition could improve visualization and segmentation of peripheral bronchi. The purpose of the present pilot study is to compare quality of segmentations under 4 CT acquisition modes: inspiration (INSP), expiration (EXP) and both with CPAP (INSP-CPAP and EXP-CPAP).  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number (up) Admin @ si @ DGC2017a Serial 2883  
Permanent link to this record
 

 
Author Marta Diez-Ferrer; Debora Gil; Elena Carreño; Susana Padrones; Samantha Aso; Vanesa Vicens; Noelia Cubero de Frutos; Rosa Lopez Lisbona; Carles Sanchez; Agnes Borras; Antoni Rosell edit  doi
openurl 
  Title Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation Type Journal Article
  Year 2017 Publication European Respiratory Journal Abbreviated Journal ERJ  
  Volume 48 Issue 60 Pages PA776  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; 600.096; 600.075; 600.145 Approved no  
  Call Number (up) Admin @ si @ DGC2017b Serial 2944  
Permanent link to this record
Select All    Deselect All
 |   | 
Details

Save Citations:
Export Records: