Abstract: Vascular tortuosity of supra-aortic vessels is widely considered one of the main reasons for failure and delays in endovascular treatment of large vessel occlusion in patients with acute ischemic stroke. Characterization of tortuosity is a challenging task due to the lack of objective, robust and effective analysis tools. We present a fully automatic method for arterial segmentation, vessel labelling and tortuosity feature extraction applied to the supra-aortic region. A sample of 566 computed tomography angiography scans from acute ischemic stroke patients (aged 74.8 ± 12.9, 51.0% females) were used for training, validation and testing of a segmentation module based on a U-Net architecture (162 cases) and a vessel labelling module powered by a graph U-Net (566 cases). Successively, 30 cases were processed for testing of a tortuosity feature extraction module. Measurements obtained through automatic processing were compared to manual annotations from two observers for a thorough validation of the method. The proposed feature extraction method presented similar performance to the inter-rater variability observed in the measurement of 33 geometrical and morphological features of the arterial anatomy in the supra-aortic region. This system will contribute to the development of more complex models to advance the treatment of stroke by adding immediate automation, objectivity, repeatability and robustness to the vascular tortuosity characterization of patients.

Abstract: Vision-based bronchoscopy (VB) models require the registration of the virtual lung model with the frames from the video bronchoscopy to provide effective guidance during the biopsy. The registration can be achieved by either tracking the position and orientation of the bronchoscopy camera or by calibrating its deviation from the pose (position and orientation) simulated in the virtual lung model. Recent advances in neural networks and temporal image processing have provided new opportunities for guided bronchoscopy. However, such progress has been hindered by the lack of comparative experimental conditions.
In the present paper, we share a novel synthetic dataset allowing for a fair comparison of methods. Moreover, this paper investigates several neural network architectures for the learning of temporal information at different levels of subject personalization. In order to improve orientation measurement, we also present a standardized comparison framework and a novel metric for camera orientation learning. Results on the dataset show that the proposed metric and architectures, as well as the standardized conditions, provide notable improvements to current state-of-the-art camera pose estimation in video bronchoscopy.

Abstract: This work addresses the detection of Helicobacter pylori a bacterium classified since 1994 as class 1 carcinogen to humans. By its highest specificity and sensitivity, the preferred diagnosis technique is the analysis of histological images with immunohistochemical staining, a process in which certain stained antibodies bind to antigens of the biological element of interest. This analysis is a time demanding task, which is currently done by an expert pathologist that visually inspects the digitized samples.
We propose to use autoencoders to learn latent patterns of healthy tissue and detect H. pylori as an anomaly in image staining. Unlike existing classification approaches, an autoencoder is able to learn patterns in an unsupervised manner (without the need of image annotations) with high performance. In particular, our model has an overall 91% of accuracy with 86\% sensitivity, 96% specificity and 0.97 AUC in the detection of H. pylori.

Abstract: A common goal of unpaired image-to-image translation is to preserve content consistency between source images and translated images while mimicking the style of the target domain. Due to biases between the datasets of both domains, many methods suffer from inconsistencies caused by the translation process. Most approaches introduced to mitigate these inconsistencies do not constrain the discriminator, leading to an even more ill-posed training setup. Moreover, none of these approaches is designed for larger crop sizes. In this work, we show that masking the inputs of a global discriminator for both domains with a content-based mask is sufficient to reduce content inconsistencies significantly. However, this strategy leads to artifacts that can be traced back to the masking process. To reduce these artifacts, we introduce a local discriminator that operates on pairs of small crops selected with a similarity sampling strategy. Furthermore, we apply this sampling strategy to sample global input crops from the source and target dataset. In addition, we propose feature-attentive denormalization to selectively incorporate content-based statistics into the generator stream. In our experiments, we show that our method achieves state-of-the-art performance in photorealistic sim-to-real translation and weather translation and also performs well in day-to-night translation. Additionally, we propose the cKVD metric, which builds on the sKVD metric and enables the examination of translation quality at the class or category level.

Abstract: Monocular Depth Estimation (MDE) is performed to produce 3D information that can be used in downstream tasks such as those related to on-board perception for Autonomous Vehicles (AVs) or driver assistance. Therefore, a relevant arising question is whether the standard metrics for MDE assessment are a good indicator of the accuracy of future MDE-based driving-related perception tasks. We address this question in this paper. In particular, we take the task of 3D object detection on point clouds as a proxy of on-board perception. We train and test state-of-the-art 3D object detectors using 3D point clouds coming from MDE models. We confront the ranking of object detection results with the ranking given by the depth estimation metrics of the MDE models. We conclude that, indeed, MDE evaluation metrics give rise to a ranking of methods that reflects relatively well the 3D object detection results we may expect. Among the different metrics, the absolute relative (abs-rel) error seems to be the best for that purpose.

Abstract: A significant research effort is focused on exploiting the amazing capacities of pretrained diffusion models for the editing of images. They either finetune the model, or invert the image in the latent space of the pretrained model. However, they suffer from two problems: (1) Unsatisfying results for selected regions, and unexpected changes in nonselected regions. (2) They require careful text prompt editing where the prompt should include all visual objects in the input image. To address this, we propose two improvements: (1) Only optimizing the input of the value linear network in the cross-attention layers, is sufficiently powerful to reconstruct a real image. (2) We propose attention regularization to preserve the object-like attention maps after editing, enabling us to obtain accurate style editing without invoking significant structural changes. We further improve the editing technique which is used for the unconditional branch of classifier-free guidance, as well as the conditional one as used by P2P. Extensive experimental prompt-editing results on a variety of images, demonstrate qualitatively and quantitatively that our method has superior editing capabilities than existing and concurrent works.