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Frederic Sampedro, Anna Domenech, Sergio Escalera, & Ignasi Carrio. (2015). Deriving global quantitative tumor response parameters from 18F-FDG PET-CT scans in patients with non-Hodgkins lymphoma. NMC - Nuclear Medicine Communications, 36(4), 328–333.
Abstract: OBJECTIVES:
The aim of the study was to address the need for quantifying the global cancer time evolution magnitude from a pair of time-consecutive positron emission tomography-computed tomography (PET-CT) scans. In particular, we focus on the computation of indicators using image-processing techniques that seek to model non-Hodgkin's lymphoma (NHL) progression or response severity.
MATERIALS AND METHODS:
A total of 89 pairs of time-consecutive PET-CT scans from NHL patients were stored in a nuclear medicine station for subsequent analysis. These were classified by a consensus of nuclear medicine physicians into progressions, partial responses, mixed responses, complete responses, and relapses. The cases of each group were ordered by magnitude following visual analysis. Thereafter, a set of quantitative indicators designed to model the cancer evolution magnitude within each group were computed using semiautomatic and automatic image-processing techniques. Performance evaluation of the proposed indicators was measured by a correlation analysis with the expert-based visual analysis.
RESULTS:
The set of proposed indicators achieved Pearson's correlation results in each group with respect to the expert-based visual analysis: 80.2% in progressions, 77.1% in partial response, 68.3% in mixed response, 88.5% in complete response, and 100% in relapse. In the progression and mixed response groups, the proposed indicators outperformed the common indicators used in clinical practice [changes in metabolic tumor volume, mean, maximum, peak standardized uptake value (SUV mean, SUV max, SUV peak), and total lesion glycolysis] by more than 40%.
CONCLUSION:
Computing global indicators of NHL response using PET-CT imaging techniques offers a strong correlation with the associated expert-based visual analysis, motivating the future incorporation of such quantitative and highly observer-independent indicators in oncological decision making or treatment response evaluation scenarios.
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Jean-Pascal Jacob, Mariella Dimiccoli, & Lionel Moisan. (2016). Active skeleton for bacteria modeling. CMBBE - Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization, 5(4), 274–286.
Abstract: The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modeling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness, orientation), an improved boundary accuracy in noisy images, and a natural bacteria-centered coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimizing an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modeling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at this http URL
Keywords: Bacteria modelling; medial axis; active contours; active skeleton; shape contraints
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Aura Hernandez-Sabate, Meritxell Joanpere, Nuria Gorgorio, & Lluis Albarracin. (2015). Mathematics learning opportunities when playing a Tower Defense Game. IJSG - International Journal of Serious Games, 57–71.
Abstract: A qualitative research study is presented herein with the purpose of identifying mathematics learning opportunities in students between 10 and 12 years old while playing a commercial version of a Tower Defense game. These learning opportunities are understood as mathematicisable moments of the game and involve the establishment of relationships between the game and mathematical problem solving. Based on the analysis of these mathematicisable moments, we conclude that the game can promote problem-solving processes and learning opportunities that can be associated with different mathematical contents that appears in mathematics curricula, thought it seems that teacher or new game elements might be needed to facilitate the processes.
Keywords: Tower Defense game; learning opportunities; mathematics; problem solving; game design
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Jean-Pascal Jacob, Mariella Dimiccoli, & L. Moisan. (2017). Active skeleton for bacteria modelling. CMBBE - Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization, 5(4), 274–286.
Abstract: The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modelling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness and orientation), an improved boundary accuracy in noisy images and a natural bacteria-centred coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimising an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modelling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at http://fluobactracker.inrialpes.fr.
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A.S. Coquel, Jean-Pascal Jacob, M. Primet, A. Demarez, Mariella Dimiccoli, T. Julou, et al. (2013). Localization of protein aggregation in Escherichia coli is governed by diffusion and nucleoid macromolecular crowding effect. PCB - Plos Computational Biology, 9(4).
Abstract: Aggregates of misfolded proteins are a hallmark of many age-related diseases. Recently, they have been linked to aging of Escherichia coli (E. coli) where protein aggregates accumulate at the old pole region of the aging bacterium. Because of the potential of E. coli as a model organism, elucidating aging and protein aggregation in this bacterium may pave the way to significant advances in our global understanding of aging. A first obstacle along this path is to decipher the mechanisms by which protein aggregates are targeted to specific intercellular locations. Here, using an integrated approach based on individual-based modeling, time-lapse fluorescence microscopy and automated image analysis, we show that the movement of aging-related protein aggregates in E. coli is purely diffusive (Brownian). Using single-particle tracking of protein aggregates in live E. coli cells, we estimated the average size and diffusion constant of the aggregates. Our results provide evidence that the aggregates passively diffuse within the cell, with diffusion constants that depend on their size in agreement with the Stokes-Einstein law. However, the aggregate displacements along the cell long axis are confined to a region that roughly corresponds to the nucleoid-free space in the cell pole, thus confirming the importance of increased macromolecular crowding in the nucleoids. We thus used 3D individual-based modeling to show that these three ingredients (diffusion, aggregation and diffusion hindrance in the nucleoids) are sufficient and necessary to reproduce the available experimental data on aggregate localization in the cells. Taken together, our results strongly support the hypothesis that the localization of aging-related protein aggregates in the poles of E. coli results from the coupling of passive diffusion-aggregation with spatially non-homogeneous macromolecular crowding. They further support the importance of “soft” intracellular structuring (based on macromolecular crowding) in diffusion-based protein localization in E. coli.
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Marc Oliu, Ciprian Corneanu, Kamal Nasrollahi, Olegs Nikisins, Sergio Escalera, Yunlian Sun, et al. (2016). Improved RGB-D-T based Face Recognition. BIO - IET Biometrics, 5(4), 297–303.
Abstract: Reliable facial recognition systems are of crucial importance in various applications from entertainment to security. Thanks to the deep-learning concepts introduced in the field, a significant improvement in the performance of the unimodal facial recognition systems has been observed in the recent years. At the same time a multimodal facial recognition is a promising approach. This study combines the latest successes in both directions by applying deep learning convolutional neural networks (CNN) to the multimodal RGB, depth, and thermal (RGB-D-T) based facial recognition problem outperforming previously published results. Furthermore, a late fusion of the CNN-based recognition block with various hand-crafted features (local binary patterns, histograms of oriented gradients, Haar-like rectangular features, histograms of Gabor ordinal measures) is introduced, demonstrating even better recognition performance on a benchmark RGB-D-T database. The obtained results in this study show that the classical engineered features and CNN-based features can complement each other for recognition purposes.
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Lluis Gomez, & Dimosthenis Karatzas. (2016). A fast hierarchical method for multi‐script and arbitrary oriented scene text extraction. IJDAR - International Journal on Document Analysis and Recognition, 19(4), 335–349.
Abstract: Typography and layout lead to the hierarchical organisation of text in words, text lines, paragraphs. This inherent structure is a key property of text in any script and language, which has nonetheless been minimally leveraged by existing text detection methods. This paper addresses the problem of text
segmentation in natural scenes from a hierarchical perspective.
Contrary to existing methods, we make explicit use of text structure, aiming directly to the detection of region groupings corresponding to text within a hierarchy produced by an agglomerative similarity clustering process over individual regions. We propose an optimal way to construct such an hierarchy introducing a feature space designed to produce text group hypotheses with
high recall and a novel stopping rule combining a discriminative classifier and a probabilistic measure of group meaningfulness based in perceptual organization. Results obtained over four standard datasets, covering text in variable orientations and different languages, demonstrate that our algorithm, while being trained in a single mixed dataset, outperforms state of the art
methods in unconstrained scenarios.
Keywords: scene text; segmentation; detection; hierarchical grouping; perceptual organisation
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Cristhian A. Aguilera-Carrasco, Angel Sappa, Cristhian Aguilera, & Ricardo Toledo. (2017). Cross-Spectral Local Descriptors via Quadruplet Network. SENS - Sensors, 17(4), 873.
Abstract: This paper presents a novel CNN-based architecture, referred to as Q-Net, to learn local feature descriptors that are useful for matching image patches from two different spectral bands. Given correctly matched and non-matching cross-spectral image pairs, a quadruplet network is trained to map input image patches to a common Euclidean space, regardless of the input spectral band. Our approach is inspired by the recent success of triplet networks in the visible spectrum, but adapted for cross-spectral scenarios, where, for each matching pair, there are always two possible non-matching patches: one for each spectrum. Experimental evaluations on a public cross-spectral VIS-NIR dataset shows that the proposed approach improves the state-of-the-art. Moreover, the proposed technique can also be used in mono-spectral settings, obtaining a similar performance to triplet network descriptors, but requiring less training data.
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Katerine Diaz, Jesus Martinez del Rincon, Aura Hernandez-Sabate, Marçal Rusiñol, & Francesc J. Ferri. (2018). Fast Kernel Generalized Discriminative Common Vectors for Feature Extraction. JMIV - Journal of Mathematical Imaging and Vision, 60(4), 512–524.
Abstract: This paper presents a supervised subspace learning method called Kernel Generalized Discriminative Common Vectors (KGDCV), as a novel extension of the known Discriminative Common Vectors method with Kernels. Our method combines the advantages of kernel methods to model complex data and solve nonlinear
problems with moderate computational complexity, with the better generalization properties of generalized approaches for large dimensional data. These attractive combination makes KGDCV specially suited for feature extraction and classification in computer vision, image processing and pattern recognition applications. Two different approaches to this generalization are proposed, a first one based on the kernel trick (KT) and a second one based on the nonlinear projection trick (NPT) for even higher efficiency. Both methodologies
have been validated on four different image datasets containing faces, objects and handwritten digits, and compared against well known non-linear state-of-art methods. Results show better discriminant properties than other generalized approaches both linear or kernel. In addition, the KGDCV-NPT approach presents a considerable computational gain, without compromising the accuracy of the model.
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Huamin Ren, Nattiya Kanhabua, Andreas Mogelmose, Weifeng Liu, Kaustubh Kulkarni, Sergio Escalera, et al. (2018). Back-dropout Transfer Learning for Action Recognition. IETCV - IET Computer Vision, 12(4), 484–491.
Abstract: Transfer learning aims at adapting a model learned from source dataset to target dataset. It is a beneficial approach especially when annotating on the target dataset is expensive or infeasible. Transfer learning has demonstrated its powerful learning capabilities in various vision tasks. Despite transfer learning being a promising approach, it is still an open question how to adapt the model learned from the source dataset to the target dataset. One big challenge is to prevent the impact of category bias on classification performance. Dataset bias exists when two images from the same category, but from different datasets, are not classified as the same. To address this problem, a transfer learning algorithm has been proposed, called negative back-dropout transfer learning (NB-TL), which utilizes images that have been misclassified and further performs back-dropout strategy on them to penalize errors. Experimental results demonstrate the effectiveness of the proposed algorithm. In particular, the authors evaluate the performance of the proposed NB-TL algorithm on UCF 101 action recognition dataset, achieving 88.9% recognition rate.
Keywords: Learning (artificial intelligence); Pattern Recognition
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Xim Cerda-Company, C. Alejandro Parraga, & Xavier Otazu. (2018). Which tone-mapping operator is the best? A comparative study of perceptual quality. JOSA A - Journal of the Optical Society of America A, 35(4), 626–638.
Abstract: Tone-mapping operators (TMO) are designed to generate perceptually similar low-dynamic range images from high-dynamic range ones. We studied the performance of fifteen TMOs in two psychophysical experiments where observers compared the digitally-generated tone-mapped images to their corresponding physical scenes. All experiments were performed in a controlled environment and the setups were
designed to emphasize different image properties: in the first experiment we evaluated the local relationships among intensity-levels, and in the second one we evaluated global visual appearance among physical scenes and tone-mapped images, which were presented side by side. We ranked the TMOs according
to how well they reproduced the results obtained in the physical scene. Our results show that ranking position clearly depends on the adopted evaluation criteria, which implies that, in general, these tone-mapping algorithms consider either local or global image attributes but rarely both. Regarding the
question of which TMO is the best, KimKautz [1] and Krawczyk [2] obtained the better results across the different experiments. We conclude that a more thorough and standardized evaluation criteria is needed to study all the characteristics of TMOs, as there is ample room for improvement in future developments.
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Marta Diez-Ferrer, Debora Gil, Elena Carreño, Susana Padrones, Samantha Aso, Vanesa Vicens, et al. (2016). Positive Airway Pressure-Enhanced CT to Improve Virtual Bronchoscopic Navigation. CHEST - Chest Journal, 150(4), 1003A.
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Alejandro Cartas, Juan Marin, Petia Radeva, & Mariella Dimiccoli. (2018). Batch-based activity recognition from egocentric photo-streams revisited. PAA - Pattern Analysis and Applications, 21(4), 953–965.
Abstract: Wearable cameras can gather large amounts of image data that provide rich visual information about the daily activities of the wearer. Motivated by the large number of health applications that could be enabled by the automatic recognition of daily activities, such as lifestyle characterization for habit improvement, context-aware personal assistance and tele-rehabilitation services, we propose a system to classify 21 daily activities from photo-streams acquired by a wearable photo-camera. Our approach combines the advantages of a late fusion ensemble strategy relying on convolutional neural networks at image level with the ability of recurrent neural networks to account for the temporal evolution of high-level features in photo-streams without relying on event boundaries. The proposed batch-based approach achieved an overall accuracy of 89.85%, outperforming state-of-the-art end-to-end methodologies. These results were achieved on a dataset consists of 44,902 egocentric pictures from three persons captured during 26 days in average.
Keywords: Egocentric vision; Lifelogging; Activity recognition; Deep learning; Recurrent neural networks
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Lichao Zhang, Abel Gonzalez-Garcia, Joost Van de Weijer, Martin Danelljan, & Fahad Shahbaz Khan. (2019). Synthetic Data Generation for End-to-End Thermal Infrared Tracking. TIP - IEEE Transactions on Image Processing, 28(4), 1837–1850.
Abstract: The usage of both off-the-shelf and end-to-end trained deep networks have significantly improved the performance of visual tracking on RGB videos. However, the lack of large labeled datasets hampers the usage of convolutional neural networks for tracking in thermal infrared (TIR) images. Therefore, most state-of-the-art methods on tracking for TIR data are still based on handcrafted features. To address this problem, we propose to use image-to-image translation models. These models allow us to translate the abundantly available labeled RGB data to synthetic TIR data. We explore both the usage of paired and unpaired image translation models for this purpose. These methods provide us with a large labeled dataset of synthetic TIR sequences, on which we can train end-to-end optimal features for tracking. To the best of our knowledge, we are the first to train end-to-end features for TIR tracking. We perform extensive experiments on the VOT-TIR2017 dataset. We show that a network trained on a large dataset of synthetic TIR data obtains better performance than one trained on the available real TIR data. Combining both data sources leads to further improvement. In addition, when we combine the network with motion features, we outperform the state of the art with a relative gain of over 10%, clearly showing the efficiency of using synthetic data to train end-to-end TIR trackers.
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Akhil Gurram, Onay Urfalioglu, Ibrahim Halfaoui, Fahd Bouzaraa, & Antonio Lopez. (2020). Semantic Monocular Depth Estimation Based on Artificial Intelligence. ITSM - IEEE Intelligent Transportation Systems Magazine, 13(4), 99–103.
Abstract: Depth estimation provides essential information to perform autonomous driving and driver assistance. A promising line of work consists of introducing additional semantic information about the traffic scene when training CNNs for depth estimation. In practice, this means that the depth data used for CNN training is complemented with images having pixel-wise semantic labels where the same raw training data is associated with both types of ground truth, i.e., depth and semantic labels. The main contribution of this paper is to show that this hard constraint can be circumvented, i.e., that we can train CNNs for depth estimation by leveraging the depth and semantic information coming from heterogeneous datasets. In order to illustrate the benefits of our approach, we combine KITTI depth and Cityscapes semantic segmentation datasets, outperforming state-of-the-art results on monocular depth estimation.
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