Abstract: In this thesis we tackle the problem of automatic characterization of human coronary vessel in Intravascular Ultrasound (IVUS) image modality. The basis for the whole characterization process is machine learning applied to multi-class problems. In all the presented approaches, the Error-Correcting Output Codes (ECOC) framework is used as central element for the design of multi-class classifiers.
Two main topics are tackled in this thesis. First, the automatic detection of the vessel borders is presented. For this purpose, a novel context-aware classifier for multi-class classification of the vessel morphology is presented, namely ECOC-DRF. Based on ECOC-DRF, the lumen border and the media-adventitia border in IVUS are robustly detected by means of a novel holistic approach, achieving an error comparable with inter-observer variability and with state of the art methods.
The two vessel borders define the atheroma area of the vessel. In this area, tissue characterization is required. For this purpose, we present a framework for automatic plaque characterization by processing both texture in IVUS images and spectral information in raw Radio Frequency data. Furthermore, a novel method for fusing in-vivo and in-vitro IVUS data for plaque characterization is presented, namely pSFFS. The method demonstrates to effectively fuse data generating a classifier that improves the tissue characterization in both in-vitro and in-vivo datasets.
A novel method for automatic video summarization in IVUS sequences is also presented. The method aims to detect the key frames of the sequence, i.e., the frames representative of morphological changes. This novel method represents the basis for video summarization in IVUS as well as the markers for the partition of the vessel into morphological and clinically interesting events.
Finally, multi-class learning based on ECOC is applied to lung tissue characterization in Computed Tomography. The novel proposed approach, based on supervised and unsupervised learning, achieves accurate tissue classification on a large and heterogeneous dataset.

Abstract: Brightness induction is the modulation of the perceived intensity of an area by the luminance of surrounding areas and reveals fundamental properties of neural organization in the visual system. Several phenomenological models have been proposed that successfully account for psychophysical data (Pessoa et al. 1995, Blakeslee and McCourt 2004, Barkan et al. 2008, Otazu et al. 2008).
Neurophysiological evidence suggests that brightness information is explicitly represented in V1 and neuronal response modulations have been observed followingluminance changes outside their receptive fields (Rossi and Paradiso, 1999).
In this work we investigate possible neural mechanisms that offer a plausible explanation for such effects. To this end, we consider the model by Z.Li (1999) which is based on biological data and focuses on the part of V1 responsible for contextual influences, namely, layer 2–3 pyramidal cells, interneurons, and horizontal intracortical connections. This model has proven to account for phenomena such as contour detection and preattentive segmentation, which share with brightness induction the relevant effect of contextual influences. In our model, the input to the network is derived from a complete multiscale and multiorientation wavelet decomposition which makes it possible to recover an image reflecting the perceived intensity. The proposed model successfully accounts for well known pyschophysical effects (among them: the White's and modified White's effects, the Todorović, Chevreul, achromatic ring patterns, and grating induction effects). Our work suggests that intra-cortical interactions in the primary visual cortex could partially explain perceptual brightness induction effects and reveals how a common general architecture may account for several different fundamental processes emerging early in the visual pathway.

Abstract: Book Series Intelligent Systems Reference Library

Abstract: The release of challenging datasets with a vast number of images, requires the development of efficient image representations and algorithms which are able to manipulate these large-scale datasets efficiently. Nowadays the Bag-of-Words (BoW) is the most successful approach in the context of object and scene classification tasks. However, its main drawback is the absence of the important spatial information. Spatial pyramids (SP) have been successfully applied to incorporate spatial information into BoW-based image representation. Observing the remarkable performance of spatial pyramids, their growing number of applications to a broad range of vision problems, and finally its geometry inclusion, a question can be asked what are the limits of spatial pyramids. Within the SP framework, the optimal way for obtaining an image spatial representation, which is able to cope with it’s most foremost shortcomings, concretely, it’s high dimensionality and the rigidity of the resulting image representation, still remains an active research domain. In summary, the main concern of this thesis is to search for the limits of spatial pyramids and try to figure out solutions for them.

Abstract: Pattern recognition is the task that aims at distinguishing objects among different classes. When such a task wants to be solved in an automatic way a crucial step is how to formally represent such patterns to the computer. Based on the different representational formalisms, we may distinguish between statistical and structural pattern recognition. The former describes objects as a set of measurements arranged in the form of what is called a feature vector. The latter assumes that relations between parts of the underlying objects need to be explicitly represented and thus it uses relational structures such as graphs for encoding their inherent information. Vector spaces are a very flexible mathematical structure that has allowed to come up with several efficient ways for the analysis of patterns under the form of feature vectors. Nevertheless, such a representation cannot explicitly cope with binary relations between parts of the objects and it is restricted to measure the exact same number of features for each pattern under study regardless of their complexity. Graph-based representations present the contrary situation. They can easily adapt to the inherent complexity of the patterns but introduce a problem of high computational complexity, hindering the design of efficient tools to process and analyse patterns.
Solving this paradox is the main goal of this thesis. The ideal situation for solving pattern recognition problems would be to represent the patterns using relational structures such as graphs, and to be able to use the wealthy repository of data processing tools from the statistical pattern recognition domain. An elegant solution to this problem is to transform the graph domain into a vector domain where any processing algorithm can be applied. In other words, by mapping each graph to a point in a vector space we automatically get access to the rich set of algorithms from the statistical domain to be applied in the graph domain. Such methodology is called graph embedding.
In this thesis we propose to associate feature vectors to graphs in a simple and very efficient way by just putting attention on the labelling information that graphs store. In particular, we count frequencies of node labels and of edges between labels. Although their locality, these features are able to robustly represent structurally global properties of graphs, when considered together in the form of a vector. We initially deal with the case of discrete attributed graphs, where features are easy to compute. The continuous case is tackled as a natural generalization of the discrete one, where rather than counting node and edge labelling instances, we count statistics of some representatives of them. We encounter how the proposed vectorial representations of graphs suffer from high dimensionality and correlation among components and we face these problems by feature selection algorithms. We also explore how the diversity of different embedding representations can be exploited in order to boost the performance of base classifiers in a multiple classifier systems framework. An extensive experimental evaluation finally shows how the methodology we propose can be efficiently computed and compete with other graph matching and embedding methodologies.

Abstract: Feature matching is a fundamental problem in Computer Vision, having multiple applications such as tracking, image classification and retrieval, shape recognition and stereo fusion. In numerous domains, it is useful to represent the local structure of the matching features to increase the matching accuracy or to make the correspondence invariant to certain transformations (affine, homography, etc. . . ). However, encoding this knowledge requires complicating the model by establishing high-order relationships between the model elements, and therefore increasing the complexity of the optimization problem.
The importance of many-to-many matching is sometimes dismissed in the literature. Most methods are restricted to perform one-to-one matching, and are usually validated on synthetic, or non-realistic datasets. In a real challenging environment, with scale, pose and illumination variations of the object of interest, as well as the presence of occlusions, clutter, and noisy observations, many-to-many matching is necessary to achieve satisfactory results. As a consequence, finding the most likely many-to-many correspondence often involves a challenging combinatorial optimization process.
In this work, we design and demonstrate matching algorithms that compute many-to-many correspondences, applied to several challenging problems. Our goal is to make use of high-order representations to improve the expressive power of the matching, at the same time that we make feasible the process of inference or optimization of such models. We effectively use graphical models as our preferred representation because they provide an elegant probabilistic framework to tackle structured prediction problems.
We introduce a matching-based tracking algorithm which performs matching between frames of a video sequence in order to solve the difficult problem of headlight tracking at night-time. We also generalise this algorithm to solve the problem of data association applied to various tracking scenarios. We demonstrate the effectiveness of such approach in real video sequences and we show that our tracking algorithm can be used to improve the accuracy of a headlight classification system.
In the second part of this work, we move from single (point) matching to dense (region) matching and we introduce a new hierarchical image representation. We make use of such model to develop a high-order many-to-many matching between pairs of images. We show that the use of high-order models in comparison to simpler models improves not only the accuracy of the results, but also the convergence speed of the inference algorithm.
Finally, we keep exploiting the idea of region matching to design a fully unsupervised image co-segmentation algorithm that is able to perform competitively with state-of-the-art supervised methods. Our method also overcomes the typical drawbacks of some of the past works, such as avoiding the necessity of variate appearances on the image backgrounds. The region matching in this case is applied to effectively exploit inter-image information. We also extend this work to perform co-segmentation of videos, being the first time that such problem is addressed, as a way to perform video object segmentation