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Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio |
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A computational framework for cancer response assessment based on oncological PET-CT scans |
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Journal Article |
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2014 |
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Computers in Biology and Medicine |
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CBM |
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55 |
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92–99 |
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Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis |
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In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks. |
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HuPBA;MILAB |
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Admin @ si @ SED2014 |
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2606 |
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Author |
Jorge Bernal; F. Javier Sanchez; Gloria Fernandez Esparrach; Debora Gil; Cristina Rodriguez de Miguel; Fernando Vilariño |
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Title |
WM-DOVA Maps for Accurate Polyp Highlighting in Colonoscopy: Validation vs. Saliency Maps from Physicians |
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Journal Article |
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2015 |
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Computerized Medical Imaging and Graphics |
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CMIG |
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43 |
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99-111 |
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Polyp localization; Energy Maps; Colonoscopy; Saliency; Valley detection |
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We introduce in this paper a novel polyp localization method for colonoscopy videos. Our method is based on a model of appearance for polyps which defines polyp boundaries in terms of valley information. We propose the integration of valley information in a robust way fostering complete, concave and continuous boundaries typically associated to polyps. This integration is done by using a window of radial sectors which accumulate valley information to create WMDOVA1 energy maps related with the likelihood of polyp presence. We perform a double validation of our maps, which include the introduction of two new databases, including the first, up to our knowledge, fully annotated database with clinical metadata associated. First we assess that the highest value corresponds with the location of the polyp in the image. Second, we show that WM-DOVA energy maps can be comparable with saliency maps obtained from physicians' fixations obtained via an eye-tracker. Finally, we prove that our method outperforms state-of-the-art computational saliency results. Our method shows good performance, particularly for small polyps which are reported to be the main sources of polyp miss-rate, which indicates the potential applicability of our method in clinical practice. |
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0895-6111 |
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MV; IAM; 600.047; 600.060; 600.075;SIAI |
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Admin @ si @ BSF2015 |
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2609 |
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Carles Sanchez; Jorge Bernal; F. Javier Sanchez; Antoni Rosell; Marta Diez-Ferrer; Debora Gil |
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Title |
Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy |
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Journal Article |
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2015 |
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International Journal of Computer Assisted Radiology and Surgery |
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IJCAR |
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10 |
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6 |
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935-945 |
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IAM; MV; 600.075 |
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Admin @ si @ SBS2015a |
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2611 |
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Mariella Dimiccoli |
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Title |
Figure-ground segregation: A fully nonlocal approach |
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Journal Article |
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2016 |
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Vision Research |
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VR |
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126 |
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308-317 |
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Figure-ground segregation; Nonlocal approach; Directional linear voting; Nonlinear diffusion |
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We present a computational model that computes and integrates in a nonlocal fashion several configural cues for automatic figure-ground segregation. Our working hypothesis is that the figural status of each pixel is a nonlocal function of several geometric shape properties and it can be estimated without explicitly relying on object boundaries. The methodology is grounded on two elements: multi-directional linear voting and nonlinear diffusion. A first estimation of the figural status of each pixel is obtained as a result of a voting process, in which several differently oriented line-shaped neighborhoods vote to express their belief about the figural status of the pixel. A nonlinear diffusion process is then applied to enforce the coherence of figural status estimates among perceptually homogeneous regions. Computer simulations fit human perception and match the experimental evidence that several cues cooperate in defining figure-ground segregation. The results of this work suggest that figure-ground segregation involves feedback from cells with larger receptive fields in higher visual cortical areas. |
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MILAB; |
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Admin @ si @ Dim2016b |
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2623 |
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Marco Pedersoli; Andrea Vedaldi; Jordi Gonzalez; Xavier Roca |
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A coarse-to-fine approach for fast deformable object detection |
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2015 |
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Pattern Recognition |
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PR |
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48 |
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5 |
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1844-1853 |
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We present a method that can dramatically accelerate object detection with part based models. The method is based on the observation that the cost of detection is likely to be dominated by the cost of matching each part to the image, and not by the cost of computing the optimal configuration of the parts as commonly assumed. Therefore accelerating detection requires minimizing the number of
part-to-image comparisons. To this end we propose a multiple-resolutions hierarchical part based model and a corresponding coarse-to-fine inference procedure that recursively eliminates from the search space unpromising part
placements. The method yields a ten-fold speedup over the standard dynamic programming approach and is complementary to the cascade-of-parts approach of [9]. Compared to the latter, our method does not have parameters to be determined empirically, which simplifies its use during the training of the model. Most importantly, the two techniques can be combined to obtain a very significant speedup, of two orders of magnitude in some cases. We evaluate our method extensively on the PASCAL VOC and INRIA datasets, demonstrating a very high increase in the detection speed with little degradation of the accuracy. |
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ISE; 600.078; 602.005; 605.001; 302.012 |
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Admin @ si @ PVG2015 |
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2628 |
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Michal Drozdzal; Santiago Segui; Petia Radeva; Carolina Malagelada; Fernando Azpiroz; Jordi Vitria |
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Title |
Motility bar: a new tool for motility analysis of endoluminal videos |
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Journal Article |
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2015 |
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Computers in Biology and Medicine |
Abbreviated Journal |
CBM |
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65 |
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320-330 |
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Small intestine; Motility; WCE; Computer vision; Image classification |
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Wireless Capsule Endoscopy (WCE) provides a new perspective of the small intestine, since it enables, for the first time, visualization of the entire organ. However, the long visual video analysis time, due to the large number of data in a single WCE study, was an important factor impeding the widespread use of the capsule as a tool for intestinal abnormalities detection. Therefore, the introduction of WCE triggered a new field for the application of computational methods, and in particular, of computer vision. In this paper, we follow the computational approach and come up with a new perspective on the small intestine motility problem. Our approach consists of three steps: first, we review a tool for the visualization of the motility information contained in WCE video; second, we propose algorithms for the characterization of two motility building-blocks: contraction detector and lumen size estimation; finally, we introduce an approach to detect segments of stable motility behavior. Our claims are supported by an evaluation performed with 10 WCE videos, suggesting that our methods ably capture the intestinal motility information. |
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MILAB;MV |
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Admin @ si @ DSR2015 |
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2635 |
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Tadashi Araki; Nobutaka Ikeda; Nilanjan Dey; Sayan Chakraborty; Luca Saba; Dinesh Kumar; Elisa Cuadrado Godia; Xiaoyi Jiang; Ajay Gupta; Petia Radeva; John R. Laird; Andrew Nicolaides; Jasjit S. Suri |
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A comparative approach of four different image registration techniques for quantitative assessment of coronary artery calcium lesions using intravascular ultrasound |
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2015 |
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Computer Methods and Programs in Biomedicine |
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CMPB |
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118 |
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2 |
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158-172 |
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MILAB |
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no |
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Admin @ si @ AID2015 |
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2640 |
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Andres Traumann; Gholamreza Anbarjafari; Sergio Escalera |
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Accurate 3D Measurement Using Optical Depth Information |
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2015 |
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Electronic Letters |
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EL |
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51 |
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18 |
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1420-1422 |
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A novel three-dimensional measurement technique is proposed. The methodology consists in mapping from the screen coordinates reported by the optical camera to the real world, and integrating distance gradients from the beginning to the end point, while also minimising the error through fitting pixel locations to a smooth curve. The results demonstrate accuracy of less than half a centimetre using Microsoft Kinect II. |
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HuPBA;MILAB |
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Admin @ si @ TAE2015 |
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2647 |
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Mohammad Rouhani; Angel Sappa |
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The Richer Representation the Better Registration |
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2013 |
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IEEE Transactions on Image Processing |
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TIP |
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22 |
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12 |
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5036-5049 |
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In this paper, the registration problem is formulated as a point to model distance minimization. Unlike most of the existing works, which are based on minimizing a point-wise correspondence term, this formulation avoids the correspondence search that is time-consuming. In the first stage, the target set is described through an implicit function by employing a linear least squares fitting. This function can be either an implicit polynomial or an implicit B-spline from a coarse to fine representation. In the second stage, we show how the obtained implicit representation is used as an interface to convert point-to-point registration into point-to-implicit problem. Furthermore, we show that this registration distance is smooth and can be minimized through the Levengberg-Marquardt algorithm. All the formulations presented for both stages are compact and easy to implement. In addition, we show that our registration method can be handled using any implicit representation though some are coarse and others provide finer representations; hence, a tradeoff between speed and accuracy can be set by employing the right implicit function. Experimental results and comparisons in 2D and 3D show the robustness and the speed of convergence of the proposed approach. |
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1057-7149 |
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ADAS |
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Admin @ si @ RoS2013 |
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2665 |
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Carolina Malagelada; Michal Drozdzal; Santiago Segui; Sara Mendez; Jordi Vitria; Petia Radeva; Javier Santos; Anna Accarino; Juan R. Malagelada; Fernando Azpiroz |
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Classification of functional bowel disorders by objective physiological criteria based on endoluminal image analysis |
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2015 |
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American Journal of Physiology-Gastrointestinal and Liver Physiology |
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AJPGI |
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309 |
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6 |
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G413--G419 |
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capsule endoscopy; computer vision analysis; functional bowel disorders; intestinal motility; machine learning |
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We have previously developed an original method to evaluate small bowel motor function based on computer vision analysis of endoluminal images obtained by capsule endoscopy. Our aim was to demonstrate intestinal motor abnormalities in patients with functional bowel disorders by endoluminal vision analysis. Patients with functional bowel disorders (n = 205) and healthy subjects (n = 136) ingested the endoscopic capsule (Pillcam-SB2, Given-Imaging) after overnight fast and 45 min after gastric exit of the capsule a liquid meal (300 ml, 1 kcal/ml) was administered. Endoluminal image analysis was performed by computer vision and machine learning techniques to define the normal range and to identify clusters of abnormal function. After training the algorithm, we used 196 patients and 48 healthy subjects, completely naive, as test set. In the test set, 51 patients (26%) were detected outside the normal range (P < 0.001 vs. 3 healthy subjects) and clustered into hypo- and hyperdynamic subgroups compared with healthy subjects. Patients with hypodynamic behavior (n = 38) exhibited less luminal closure sequences (41 ± 2% of the recording time vs. 61 ± 2%; P < 0.001) and more static sequences (38 ± 3 vs. 20 ± 2%; P < 0.001); in contrast, patients with hyperdynamic behavior (n = 13) had an increased proportion of luminal closure sequences (73 ± 4 vs. 61 ± 2%; P = 0.029) and more high-motion sequences (3 ± 1 vs. 0.5 ± 0.1%; P < 0.001). Applying an original methodology, we have developed a novel classification of functional gut disorders based on objective, physiological criteria of small bowel function. |
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American Physiological Society |
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MILAB; OR;MV |
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Admin @ si @ MDS2015 |
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2666 |
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R.A.Bendezu; E.Barba; E.Burri; D.Cisternas; Carolina Malagelada; Santiago Segui; Anna Accarino; S.Quiroga; E.Monclus; I.Navazo |
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Intestinal gas content and distribution in health and in patients with functional gut symptoms |
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2015 |
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Neurogastroenterology & Motility |
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NEUMOT |
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27 |
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9 |
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1249-1257 |
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BACKGROUND:
The precise relation of intestinal gas to symptoms, particularly abdominal bloating and distension remains incompletely elucidated. Our aim was to define the normal values of intestinal gas volume and distribution and to identify abnormalities in relation to functional-type symptoms.
METHODS:
Abdominal computed tomography scans were evaluated in healthy subjects (n = 37) and in patients in three conditions: basal (when they were feeling well; n = 88), during an episode of abdominal distension (n = 82) and after a challenge diet (n = 24). Intestinal gas content and distribution were measured by an original analysis program. Identification of patients outside the normal range was performed by machine learning techniques (one-class classifier). Results are expressed as median (IQR) or mean ± SE, as appropriate.
KEY RESULTS:
In healthy subjects the gut contained 95 (71, 141) mL gas distributed along the entire lumen. No differences were detected between patients studied under asymptomatic basal conditions and healthy subjects. However, either during a spontaneous bloating episode or once challenged with a flatulogenic diet, luminal gas was found to be increased and/or abnormally distributed in about one-fourth of the patients. These patients detected outside the normal range by the classifier exhibited a significantly greater number of abnormal features than those within the normal range (3.7 ± 0.4 vs 0.4 ± 0.1; p < 0.001).
CONCLUSIONS & INFERENCES:
The analysis of a large cohort of subjects using original techniques provides unique and heretofore unavailable information on the volume and distribution of intestinal gas in normal conditions and in relation to functional gastrointestinal symptoms. |
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MILAB |
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Admin @ si @ BBB2015 |
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2667 |
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Fahad Shahbaz Khan; Jiaolong Xu; Muhammad Anwer Rao; Joost Van de Weijer; Andrew Bagdanov; Antonio Lopez |
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Recognizing Actions through Action-specific Person Detection |
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2015 |
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IEEE Transactions on Image Processing |
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TIP |
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24 |
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11 |
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4422-4432 |
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Action recognition in still images is a challenging problem in computer vision. To facilitate comparative evaluation independently of person detection, the standard evaluation protocol for action recognition uses an oracle person detector to obtain perfect bounding box information at both training and test time. The assumption is that, in practice, a general person detector will provide candidate bounding boxes for action recognition. In this paper, we argue that this paradigm is suboptimal and that action class labels should already be considered during the detection stage. Motivated by the observation that body pose is strongly conditioned on action class, we show that: 1) the existing state-of-the-art generic person detectors are not adequate for proposing candidate bounding boxes for action classification; 2) due to limited training examples, the direct training of action-specific person detectors is also inadequate; and 3) using only a small number of labeled action examples, the transfer learning is able to adapt an existing detector to propose higher quality bounding boxes for subsequent action classification. To the best of our knowledge, we are the first to investigate transfer learning for the task of action-specific person detection in still images. We perform extensive experiments on two benchmark data sets: 1) Stanford-40 and 2) PASCAL VOC 2012. For the action detection task (i.e., both person localization and classification of the action performed), our approach outperforms methods based on general person detection by 5.7% mean average precision (MAP) on Stanford-40 and 2.1% MAP on PASCAL VOC 2012. Our approach also significantly outperforms the state of the art with a MAP of 45.4% on Stanford-40 and 31.4% on PASCAL VOC 2012. We also evaluate our action detection approach for the task of action classification (i.e., recognizing actions without localizing them). For this task, our approach, without using any ground-truth person localization at test tim- , outperforms on both data sets state-of-the-art methods, which do use person locations. |
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ADAS; LAMP; 600.076; 600.079 |
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Admin @ si @ KXR2015 |
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2668 |
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Author |
Jiaolong Xu; Sebastian Ramos; David Vazquez; Antonio Lopez |
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Title |
Hierarchical Adaptive Structural SVM for Domain Adaptation |
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Journal Article |
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Year |
2016 |
Publication |
International Journal of Computer Vision |
Abbreviated Journal |
IJCV |
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Volume |
119 |
Issue |
2 |
Pages |
159-178 |
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Keywords |
Domain Adaptation; Pedestrian Detection |
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Abstract |
A key topic in classification is the accuracy loss produced when the data distribution in the training (source) domain differs from that in the testing (target) domain. This is being recognized as a very relevant problem for many
computer vision tasks such as image classification, object detection, and object category recognition. In this paper, we present a novel domain adaptation method that leverages multiple target domains (or sub-domains) in a hierarchical adaptation tree. The core idea is to exploit the commonalities and differences of the jointly considered target domains.
Given the relevance of structural SVM (SSVM) classifiers, we apply our idea to the adaptive SSVM (A-SSVM), which only requires the target domain samples together with the existing source-domain classifier for performing the desired adaptation. Altogether, we term our proposal as hierarchical A-SSVM (HA-SSVM).
As proof of concept we use HA-SSVM for pedestrian detection, object category recognition and face recognition. In the former we apply HA-SSVM to the deformable partbased model (DPM) while in the rest HA-SSVM is applied to multi-category classifiers. We will show how HA-SSVM is effective in increasing the detection/recognition accuracy with respect to adaptation strategies that ignore the structure of the target data. Since, the sub-domains of the target data are not always known a priori, we shown how HA-SSVM can incorporate sub-domain discovery for object category recognition. |
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Springer US |
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0920-5691 |
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Notes |
ADAS; 600.085; 600.082; 600.076 |
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Admin @ si @ XRV2016 |
Serial |
2669 |
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Author |
G.Blasco; Simone Balocco; J.Puig; J.Sanchez-Gonzalez; W.Ricart; J.Daunis-I-Estadella; X.Molina; S.Pedraza; J.M.Fernandez-Real |
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Title |
Carotid pulse wave velocity by magnetic resonance imaging is increased in middle-aged subjects with the metabolic syndrome |
Type |
Journal Article |
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Year |
2015 |
Publication |
International Journal of Cardiovascular Imaging |
Abbreviated Journal |
ICJI |
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Volume |
31 |
Issue |
3 |
Pages |
603-612 |
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Keywords |
Metabolic syndrome; Arterial stiffness; Pulse wave velocity; Carotid artery; Magnetic resonance |
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Abstract |
Arterial pulse wave velocity (PWV), an independent predictor of cardiovascular disease, physiologically increases with age; however, growing evidence suggests metabolic syndrome (MetS) accelerates this increase. Magnetic resonance imaging (MRI) enables reliable noninvasive assessment of arterial stiffness by measuring arterial PWV in specific vascular segments. We investigated the association between the presence of MetS and its components with carotid PWV (cPWV) in asymptomatic subjects without diabetes. We assessed cPWV by MRI in 61 individuals (mean age, 55.3 ± 14.1 years; median age, 55 years): 30 with MetS and 31 controls with similar age, sex, body mass index, and LDL-cholesterol levels. The study population was dichotomized by the median age. To remove the physiological association between PWV and age, unpaired t tests and multiple regression analyses were performed using the residuals of the regression between PWV and age. cPWV was higher in middle-aged subjects with MetS than in those without (p = 0.001), but no differences were found in elder subjects (p = 0.313). cPWV was associated with diastolic blood pressure (r = 0.276, p = 0.033) and waist circumference (r = 0.268, p = 0.038). The presence of MetS was associated with increased cPWV regardless of age, sex, blood pressure, and waist (p = 0.007). The MetS components contributing independently to an increased cPWV were hypertension (p = 0.018) and hypertriglyceridemia (p = 0.002). The presence of MetS is associated with an increased cPWV in middle-aged subjects. In particular, hypertension and hypertriglyceridemia may contribute to early progression of carotid stiffness. |
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Springer Netherlands |
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1569-5794 |
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MILAB |
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no |
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Admin @ si @ BBP2015 |
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2670 |
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Author |
Lluis Garrido; M.Guerrieri; Laura Igual |
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Title |
Image Segmentation with Cage Active Contours |
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Journal Article |
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Year |
2015 |
Publication |
IEEE Transactions on Image Processing |
Abbreviated Journal |
TIP |
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Volume |
24 |
Issue |
12 |
Pages |
5557 - 5566 |
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Keywords |
Level sets; Mean value coordinates; Parametrized active contours; level sets; mean value coordinates |
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Abstract |
In this paper, we present a framework for image segmentation based on parametrized active contours. The evolving contour is parametrized according to a reduced set of control points that form a closed polygon and have a clear visual interpretation. The parametrization, called mean value coordinates, stems from the techniques used in computer graphics to animate virtual models. Our framework allows to easily formulate region-based energies to segment an image. In particular, we present three different local region-based energy terms: 1) the mean model; 2) the Gaussian model; 3) and the histogram model. We show the behavior of our method on synthetic and real images and compare the performance with state-of-the-art level set methods. |
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1057-7149 |
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MILAB |
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Admin @ si @ GGI2015 |
Serial |
2673 |
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