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Simone Balocco, Carlo Gatta, Francesco Ciompi, A. Wahle, Petia Radeva, S. Carlier, et al. (2014). Standardized evaluation methodology and reference database for evaluating IVUS image segmentation. CMIG - Computerized Medical Imaging and Graphics, 38(2), 70–90.
Abstract: This paper describes an evaluation framework that allows a standardized and quantitative comparison of IVUS lumen and media segmentation algorithms. This framework has been introduced at the MICCAI 2011 Computing and Visualization for (Intra)Vascular Imaging (CVII) workshop, comparing the results of eight teams that participated.
We describe the available data-base comprising of multi-center, multi-vendor and multi-frequency IVUS datasets, their acquisition, the creation of the reference standard and the evaluation measures. The approaches address segmentation of the lumen, the media, or both borders; semi- or fully-automatic operation; and 2-D vs. 3-D methodology. Three performance measures for quantitative analysis have
been proposed. The results of the evaluation indicate that segmentation of the vessel lumen and media is possible with an accuracy that is comparable to manual annotation when semi-automatic methods are used, as well as encouraging results can be obtained also in case of fully-automatic segmentation. The analysis performed in this paper also highlights the challenges in IVUS segmentation that remains to be
solved.
Keywords: IVUS (intravascular ultrasound); Evaluation framework; Algorithm comparison; Image segmentation
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Frederic Sampedro, Sergio Escalera, Anna Domenech, & Ignasi Carrio. (2015). Automatic Tumor Volume Segmentation in Whole-Body PET/CT Scans: A Supervised Learning Approach Source. JMIHI - Journal of Medical Imaging and Health Informatics, 5(2), 192–201.
Abstract: Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level.
Keywords: CONTEXTUAL CLASSIFICATION; PET/CT; SUPERVISED LEARNING; TUMOR SEGMENTATION; WHOLE BODY
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Cristina Palmero, Jordi Esquirol, Vanessa Bayo, Miquel Angel Cos, Pouya Ahmadmonfared, Joan Salabert, et al. (2017). Automatic Sleep System Recommendation by Multi-modal RBG-Depth-Pressure Anthropometric Analysis. IJCV - International Journal of Computer Vision, 122(2), 212–227.
Abstract: This paper presents a novel system for automatic sleep system recommendation using RGB, depth and pressure information. It consists of a validated clinical knowledge-based model that, along with a set of prescription variables extracted automatically, obtains a personalized bed design recommendation. The automatic process starts by performing multi-part human body RGB-D segmentation combining GrabCut, 3D Shape Context descriptor and Thin Plate Splines, to then extract a set of anthropometric landmark points by applying orthogonal plates to the segmented human body. The extracted variables are introduced to the computerized clinical model to calculate body circumferences, weight, morphotype and Body Mass Index categorization. Furthermore, pressure image analysis is performed to extract pressure values and at-risk points, which are also introduced to the model to eventually obtain the final prescription of mattress, topper, and pillow. We validate the complete system in a set of 200 subjects, showing accurate category classification and high correlation results with respect to manual measures.
Keywords: Sleep system recommendation; RGB-Depth data Pressure imaging; Anthropometric landmark extraction; Multi-part human body segmentation
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Cristina Palmero, Albert Clapes, Chris Bahnsen, Andreas Møgelmose, Thomas B. Moeslund, & Sergio Escalera. (2016). Multi-modal RGB-Depth-Thermal Human Body Segmentation. IJCV - International Journal of Computer Vision, 118(2), 217–239.
Abstract: This work addresses the problem of human body segmentation from multi-modal visual cues as a first stage of automatic human behavior analysis. We propose a novel RGB–depth–thermal dataset along with a multi-modal segmentation baseline. The several modalities are registered using a calibration device and a registration algorithm. Our baseline extracts regions of interest using background subtraction, defines a partitioning of the foreground regions into cells, computes a set of image features on those cells using different state-of-the-art feature extractions, and models the distribution of the descriptors per cell using probabilistic models. A supervised learning algorithm then fuses the output likelihoods over cells in a stacked feature vector representation. The baseline, using Gaussian mixture models for the probabilistic modeling and Random Forest for the stacked learning, is superior to other state-of-the-art methods, obtaining an overlap above 75 % on the novel dataset when compared to the manually annotated ground-truth of human segmentations.
Keywords: Human body segmentation; RGB ; Depth Thermal
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Frederic Sampedro, Anna Domenech, Sergio Escalera, & Ignasi Carrio. (2017). Computing quantitative indicators of structural renal damage in pediatric DMSA scans. REMNIM - Revista Española de Medicina Nuclear e Imagen Molecular, 36(2), 72–77.
Abstract: OBJECTIVES:
The proposal and implementation of a computational framework for the quantification of structural renal damage from 99mTc-dimercaptosuccinic acid (DMSA) scans. The aim of this work is to propose, implement, and validate a computational framework for the quantification of structural renal damage from DMSA scans and in an observer-independent manner.
MATERIALS AND METHODS:
From a set of 16 pediatric DMSA-positive scans and 16 matched controls and using both expert-guided and automatic approaches, a set of image-derived quantitative indicators was computed based on the relative size, intensity and histogram distribution of the lesion. A correlation analysis was conducted in order to investigate the association of these indicators with other clinical data of interest in this scenario, including C-reactive protein (CRP), white cell count, vesicoureteral reflux, fever, relative perfusion, and the presence of renal sequelae in a 6-month follow-up DMSA scan.
RESULTS:
A fully automatic lesion detection and segmentation system was able to successfully classify DMSA-positive from negative scans (AUC=0.92, sensitivity=81% and specificity=94%). The image-computed relative size of the lesion correlated with the presence of fever and CRP levels (p<0.05), and a measurement derived from the distribution histogram of the lesion obtained significant performance results in the detection of permanent renal damage (AUC=0.86, sensitivity=100% and specificity=75%).
CONCLUSIONS:
The proposal and implementation of a computational framework for the quantification of structural renal damage from DMSA scans showed a promising potential to complement visual diagnosis and non-imaging indicators.
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