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Santiago Segui, Michal Drozdzal, Fernando Vilariño, Carolina Malagelada, Fernando Azpiroz, Petia Radeva, et al. (2012). Categorization and Segmentation of Intestinal Content Frames for Wireless Capsule Endoscopy. TITB - IEEE Transactions on Information Technology in Biomedicine, 16(6), 1341–1352.
Abstract: Wireless capsule endoscopy (WCE) is a device that allows the direct visualization of gastrointestinal tract with minimal discomfort for the patient, but at the price of a large amount of time for screening. In order to reduce this time, several works have proposed to automatically remove all the frames showing intestinal content. These methods label frames as {intestinal content – clear} without discriminating between types of content (with different physiological meaning) or the portion of image covered. In addition, since the presence of intestinal content has been identified as an indicator of intestinal motility, its accurate quantification can show a potential clinical relevance. In this paper, we present a method for the robust detection and segmentation of intestinal content in WCE images, together with its further discrimination between turbid liquid and bubbles. Our proposal is based on a twofold system. First, frames presenting intestinal content are detected by a support vector machine classifier using color and textural information. Second, intestinal content frames are segmented into {turbid, bubbles, and clear} regions. We show a detailed validation using a large dataset. Our system outperforms previous methods and, for the first time, discriminates between turbid from bubbles media.
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Michal Drozdzal, Santiago Segui, Petia Radeva, Carolina Malagelada, Fernando Azpiroz, & Jordi Vitria. (2015). Motility bar: a new tool for motility analysis of endoluminal videos. CBM - Computers in Biology and Medicine, 65, 320–330.
Abstract: Wireless Capsule Endoscopy (WCE) provides a new perspective of the small intestine, since it enables, for the first time, visualization of the entire organ. However, the long visual video analysis time, due to the large number of data in a single WCE study, was an important factor impeding the widespread use of the capsule as a tool for intestinal abnormalities detection. Therefore, the introduction of WCE triggered a new field for the application of computational methods, and in particular, of computer vision. In this paper, we follow the computational approach and come up with a new perspective on the small intestine motility problem. Our approach consists of three steps: first, we review a tool for the visualization of the motility information contained in WCE video; second, we propose algorithms for the characterization of two motility building-blocks: contraction detector and lumen size estimation; finally, we introduce an approach to detect segments of stable motility behavior. Our claims are supported by an evaluation performed with 10 WCE videos, suggesting that our methods ably capture the intestinal motility information.
Keywords: Small intestine; Motility; WCE; Computer vision; Image classification
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Fernando Vilariño, Ludmila I. Kuncheva, & Petia Radeva. (2006). ROC curves and video analysis optimization in intestinal capsule endoscopy. PRL - Pattern Recognition Letters, 27(8), 875–881.
Abstract: Wireless capsule endoscopy involves inspection of hours of video material by a highly qualified professional. Time episodes corresponding to intestinal contractions, which are of interest to the physician constitute about 1% of the video. The problem is to label automatically time episodes containing contractions so that only a fraction of the video needs inspection. As the classes of contraction and non-contraction images in the video are largely imbalanced, ROC curves are used to optimize the trade-off between false positive and false negative rates. Classifier ensemble methods and simple classifiers were examined. Our results reinforce the claims from recent literature that classifier ensemble methods specifically designed for imbalanced problems have substantial advantages over simple classifiers and standard classifier ensembles. By using ROC curves with the bagging ensemble method the inspection time can be drastically reduced at the expense of a small fraction of missed contractions.
Keywords: ROC curves; Classification; Classifiers ensemble; Detection of intestinal contractions; Imbalanced classes; Wireless capsule endoscopy
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Miguel Reyes, Albert Clapes, Jose Ramirez, Juan R Revilla, & Sergio Escalera. (2013). Automatic Digital Biometry Analysis based on Depth Maps. COMPUTIND - Computers in Industry, 64(9), 1316–1325.
Abstract: World Health Organization estimates that 80% of the world population is affected by back-related disorders during his life. Current practices to analyze musculo-skeletal disorders (MSDs) are expensive, subjective, and invasive. In this work, we propose a tool for static body posture analysis and dynamic range of movement estimation of the skeleton joints based on 3D anthropometric information from multi-modal data. Given a set of keypoints, RGB and depth data are aligned, depth surface is reconstructed, keypoints are matched, and accurate measurements about posture and spinal curvature are computed. Given a set of joints, range of movement measurements is also obtained. Moreover, gesture recognition based on joint movements is performed to look for the correctness in the development of physical exercises. The system shows high precision and reliable measurements, being useful for posture reeducation purposes to prevent MSDs, as well as tracking the posture evolution of patients in rehabilitation treatments.
Keywords: Multi-modal data fusion; Depth maps; Posture analysis; Anthropometric data; Musculo-skeletal disorders; Gesture analysis
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Simeon Petkov, Xavier Carrillo, Petia Radeva, & Carlo Gatta. (2014). Diaphragm border detection in coronary X-ray angiographies: New method and applications. CMIG - Computerized Medical Imaging and Graphics, 38(4), 296–305.
Abstract: X-ray angiography is widely used in cardiac disease diagnosis during or prior to intravascular interventions. The diaphragm motion and the heart beating induce gray-level changes, which are one of the main obstacles in quantitative analysis of myocardial perfusion. In this paper we focus on detecting the diaphragm border in both single images or whole X-ray angiography sequences. We show that the proposed method outperforms state of the art approaches. We extend a previous publicly available data set, adding new ground truth data. We also compose another set of more challenging images, thus having two separate data sets of increasing difficulty. Finally, we show three applications of our method: (1) a strategy to reduce false positives in vessel enhanced images; (2) a digital diaphragm removal algorithm; (3) an improvement in Myocardial Blush Grade semi-automatic estimation.
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