Abstract: Two key factors affecting the performance of Error Correcting Output Codes (ECOC) in multiclass classification problems are the independence of binary classifiers and the problem-dependent coding design. In this paper, we propose an evolutionary algorithm-based approach to the design of an application-dependent codematrix in the ECOC framework. The central idea of this work is to design a three-dimensional codematrix, where the third dimension is the feature space of the problem domain. In order to do that, we consider the feature space in the design process of the codematrix with the aim of improving the independence and accuracy of binary classifiers. The proposed method takes advantage of some basic concepts of ensemble classification, such as diversity of classifiers, and also benefits from the evolutionary approach for optimizing the three-dimensional codematrix, taking into account the problem domain. We provide a set of experimental results using a set of benchmark datasets from the UCI Machine Learning Repository, as well as two real multiclass Computer Vision problems. Both sets of experiments are conducted using two different base learners: Neural Networks and Decision Trees. The results show that the proposed method increases the classification accuracy in comparison with the state-of-the-art ECOC coding techniques.

Abstract: Segmentation of coronary arteries in X-Ray angiography is a fundamental tool to evaluate arterial diseases and choose proper coronary treatment. The accurate segmentation of coronary arteries has become an important topic for the registration of different modalities which allows physicians rapid access to different medical imaging information from Computed Tomography (CT) scans or Magnetic Resonance Imaging (MRI). In this paper, we propose an accurate fully automatic algorithm based on Graph-cuts for vessel centerline extraction, caliber estimation, and catheter detection. Vesselness, geodesic paths, and a new multi-scale edgeness map are combined to customize the Graph-cuts approach to the segmentation of tubular structures, by means of a global optimization of the Graph-cuts energy function. Moreover, a novel supervised learning methodology that integrates local and contextual information is proposed for automatic catheter detection. We evaluate the method performance on three datasets coming from different imaging systems. The method performs as good as the expert observer w.r.t. centerline detection and caliber estimation. Moreover, the method discriminates between arteries and catheter with an accuracy of 96.5%, sensitivity of 72%, and precision of 97.4%.