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Petia Radeva, & Enric Marti. (1995). "An improved model of snakes for model-based segmentation " In Proceedings of Computer Analysis of Images and Patterns (pp. 515–520).
Abstract: The main advantage of segmentation by snakes consists in its ability to incorporate smoothness constraints on the detected shapes that can occur. Likewise, we propose to model snakes with other properties that reflect the information provided about the object of interest in a different extent. We consider different kinds of snakes, those searching for contours with a certain direction, those preserving an object’s model, those seeking for symmetry, those expanding open, etc. The availability of such a collection of snakes allows not only the more complete use of the knowledge about the segmented object, but also to solve some problems of the existing snakes. Our experiments on segmentation of facial features justify the usefulness of snakes with different properties.
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Oriol Rodriguez-Leon, Eduard Fernandez-Nofrerias, Josefina Mauri, Vicente del Valle, Debora Gil, A.Barrios, et al. (2006)." Perfusion ratio: A new tool to objectively assess microcirculation perfusion after primary Percutaneous Coronary Intervention" In World Congress of Cardiology (859). Barcelona (Spain).
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Oriol Rodriguez-Leon, Debora Gil, Eduard Fernandez-Nofrerias, H.Tizon, S.Montserrat, Vicente del Valle, et al. (2007)." Caracterització de la Perfusió Miocàrdica mitjançant anàlisi estadístic de l espectre en l angiografia de contrast" In XIX Congrés de la Societat Catalana de Cardiologia de Barcelona (130). Barcelona (Spain).
Abstract: La valoració de la integritat de la microcirculació coronària aporta informació pronòstica en pacients amb infart agut de miocardi en els que es realitza angioplastia primària. Aquesta valoració és subjectiva i presenta una important variabilitat si no es duta a terme per personal experimentat. Presentem una eina d’anàlisi d’imatge que permet fer una valoració de la microcirculació coronària a partir de seqüències d’angiografia. Hem analitzat les variacions locals en el nivell de gris de la imatge durant la seqüència angiogràfica. Hem identificat els principals fenòmens observats (respiració, batec cardíac, tinció arterial, tinció miocàrdica i soroll radiològic) mitjançant un anàlisi estadístic de l’espectre de Fourier de l’evolució al llarg del temps de la mitja local. Aquest mateix anàlisis permet determinat la influència de cadascun d’ells en la extracció del patró de tinció i selecciona la respiració com el fenomen que més distorsiona el patró de tinció original. Els descriptors proposats s’obtenen fora del rang espectral respiratori. Hem testat la seva capacitat per a detectar els tres fenòmens principals (tinció miocàrdica (MS), tinció arterial (AS) i soroll (NS)) independentment de la respiració. La capacitat de discriminació dels descriptors ha estat valorada mitjançant un mètode de crossvalidation en 30 seqüències d’angiografia. Els descriptors emprats permeten caracteritzar la tinció miocàrdica amb una alta eficiència i fiabilitat. A més no hi ha diferències significatives en l’anàlisi de les seqüències obtingudes amb el pacient respirant amb normalitat o en apnea
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David Roche, Debora Gil, & Jesus Giraldo. (2011). "An inference model for analyzing termination conditions of Evolutionary Algorithms " In 14th Congrès Català en Intel·ligencia Artificial (pp. 216–225).
Abstract: In real-world problems, it is mandatory to design a termination condition for Evolutionary Algorithms (EAs) ensuring stabilization close to the unknown optimum. Distribution-based quantities are good candidates as far as suitable parameters are used. A main limitation for application to real-world problems is that such parameters strongly depend on the topology of the objective function, as well as, the EA paradigm used.
We claim that the termination problem would be fully solved if we had a model measuring to what extent a distribution-based quantity asymptotically behaves like the solution accuracy. We present a regression-prediction model that relates any two given quantities and reports if they can be statistically swapped as termination conditions. Our framework is applied to two issues. First, exploring if the parameters involved in the computation of distribution-based quantities influence their asymptotic behavior. Second, to what extent existing distribution-based quantities can be asymptotically exchanged for the accuracy of the EA solution.
Keywords: Evolutionary Computation Convergence, Termination Conditions, Statistical Inference
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David Roche, Debora Gil, & Jesus Giraldo. (2011). "Using statistical inference for designing termination conditions ensuring convergence of Evolutionary Algorithms " In 11th European Conference on Artificial Life.
Abstract: A main challenge in Evolutionary Algorithms (EAs) is determining a termination condition ensuring stabilization close to the optimum in real-world applications. Although for known test functions distribution-based quantities are good candidates (as far as suitable parameters are used), in real-world problems an open question still remains unsolved. How can we estimate an upper-bound for the termination condition value ensuring a given accuracy for the (unknown) EA solution?
We claim that the termination problem would be fully solved if we defined a quantity (depending only on the EA output) behaving like the solution accuracy. The open question would be, then, satisfactorily answered if we had a model relating both quantities, since accuracy could be predicted from the alternative quantity. We present a statistical inference framework addressing two topics: checking the correlation between the two quantities and defining a regression model for predicting (at a given confidence level) accuracy values from the EA output.
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David Roche, Debora Gil, & Jesus Giraldo. (2012). "Assessing agonist efficacy in an uncertain Em world " In A. Christopoulus and M. Bouvier (Ed.), 40th Keystone Symposia on mollecular and celular biology (79). Keystone Symposia.
Abstract: The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.
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Oriol Rodriguez-Leon, Josefina Mauri, Eduard Fernandez-Nofrerias, M.Gomez, Antonio Tovar, L.Cano, et al. (2002)." Ecografia Intracoronària: Segmentació Automàtica de area de la llum" In XXXVIII Congreso Nacional de la Sociedad Española de Cardiología..
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Debora Gil, Aura Hernandez-Sabate, Antoni Carol, Oriol Rodriguez, & Petia Radeva. (2005). "A Deterministic-Statistic Adventitia Detection in IVUS Images " In 3rd International workshop on International Workshop on Functional Imaging and Modeling of the Heart (pp. 65–74).
Abstract: Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.
Keywords: Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation
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Debora Gil, Aura Hernandez-Sabate, Antoni Carol, Oriol Rodriguez, & Petia Radeva. (2005). "A Deterministic-Statistic Adventitia Detection in IVUS Images " In ESC Congress. ,Sweden (EU).
Abstract: Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.
Keywords: Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation
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Oriol Rodriguez-Leon, Josefina Mauri, Eduard Fernandez-Nofrerias, Vicente de Valle, E.Garcia, A.Barrios, et al. (2006)." Analysis of the changes in angiography local grey-level values to determine myocardial perfusion" In World Congress of Cardiology (862). Barcelona (Spain).
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