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Joel Barajas, Jaume Garcia, Karla Lizbeth Caballero, Francesc Carreras, Sandra Pujades, & Petia Radeva. (2006). "Correction of Misalignment Artifacts Among 2-D Cardiac MR Images in 3-D Space " In 1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) (Vol. 3217, pp. 114–121). Copenhagen (Denmark).
Abstract: Cardiac Magnetic Resonance images offer the opportunity to study the heart in detail. One of the main issues in its modelling is to create an accurate 3-D reconstruction of the left ventricle from 2-D views. A first step to achieve this goal is the correct registration among the different image planes due to patient movements. In this article, we present an accurate method to correct displacement artifacts using the Normalized Mutual Information. Here, the image views are treated as planes in order to diminish the approximation error caused by the association of a certain thickness, and moved simultaneously to avoid any kind of bias in the alignment process. This method has been validated using real and syntectic plane displacements, yielding promising results.
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Joel Barajas, Jaume Garcia, Francesc Carreras, Sandra Pujades, & Petia Radeva. (2005). "Angle Images Using Gabor Filters in Cardiac Tagged MRI " In Proceeding of the 2005 conference on Artificial Intelligence Research and Development (pp. 107–114). Amsterdam, The Netherlands: IOS Press.
Abstract: Tagged Magnetic Resonance Imaging (MRI) is a non-invasive technique used to examine cardiac deformation in vivo. An Angle Image is a representation of a Tagged MRI which recovers the relative position of the tissue respect to the distorted tags. Thus cardiac deformation can be estimated. This paper describes a new approach to generate Angle Images using a bank of Gabor filters in short axis cardiac Tagged MRI. Our method improves the Angle Images obtained by global techniques, like HARP, with a local frequency analysis. We propose to use the phase response of a combination of a Gabor filters bank, and use it to find a more precise deformation of the left ventricle. We demonstrate the accuracy of our method over HARP by several experimental results.
Keywords: Angle Images, Gabor Filters, Harp, Tagged Mri
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Joan Serrat, & Enric Marti. (1991)." Elastic matching using interpolation splines" In IV Spanish Symposium of Pattern Recognition and image Analysis.
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Joan M. Nuñez, Debora Gil, & Fernando Vilariño. (2013). "Finger joint characterization from X-ray images for rheymatoid arthritis assessment " In 6th International Conference on Biomedical Electronics and Devices (pp. 288–292). SciTePress.
Abstract: In this study we propose amodular systemfor automatic rheumatoid arthritis assessment which provides a joint space width measure. A hand joint model is proposed based on the accurate analysis of a X-ray finger joint image sample set. This model shows that the sclerosis and the lower bone are the main necessary features in order to perform a proper finger joint characterization. We propose sclerosis and lower bone detection methods as well as the experimental setup necessary for its performance assessment. Our characterization is used to propose and compute a joint space width score which is shown to be related to the different degrees of arthritis. This assertion is verified by comparing our proposed score with Sharp Van der Heijde score, confirming that the lower our score is the more advanced is the patient affection.
Keywords: Rheumatoid Arthritis; X-Ray; Hand Joint; Sclerosis; Sharp Van der Heijde
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Joan M. Nuñez. (2011). "Computer vision techniques for characterization of finger joints in X-ray image " (Dr. Fernando Vilariño and Dra. Debora Gil, Ed.) (Vol. 165). Master's thesis, , .
Abstract: Rheumatoid arthritis (RA) is an autoimmune inflammatory type of arthritis which mainly affects hands on its first stages. Though it is a chronic disease and there is no cure for it, treatments require an accurate assessment of illness evolution. Such assessment is based on evaluation of hand X-ray images by using one of the several available semi-quantitative methods. This task requires highly trained medical personnel. That is why the automation of the assessment would allow professionals to save time and effort. Two stages are involved in this task. Firstly, the joint detection, afterwards, the joint characterization. Unlike the little existing previous work, this contribution clearly separates those two stages and sets the foundations of a modular assessment system focusing on the characterization stage. A hand joint dataset is created and an accurate data analysis is achieved in order to identify relevant features. Since the sclerosis and the lower bone were decided to be the most important features, different computer vision techniques were used in order to develop a detector system for both of them. Joint space width measures are provided and their correlation with Sharp-Van der Heijde is verified
Keywords: Rheumatoid arthritis, X-ray, Sharp Van der Heijde, joint characterization, sclerosis detection, bone detection, edge, ridge
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Jaume Garcia, Petia Radeva, & Francesc Carreras. (2004). "Combining Spectral and Active Shape methods to Track Tagged MRI " In Recent Advances in Artificial Intelligence Research and Development (pp. 37–44). IOS Press.
Abstract: Tagged magnetic resonance is a very usefull and unique tool that provides a complete local and global knowledge of the left ventricle (LV) motion. In this article we introduce a method capable of tracking and segmenting the LV. Spectral methods are applied in order to obtain the so called HARP images which encode information about movement and are the base for LV point-tracking. For segmentation we use Active Shapes (ASM) that model LV shape variation in order to overcome possible local misplacements of the boundary. We finally show experiments on both synthetic and real data which appear to be very promising.
Keywords: MR; tagged MR; ASM; LV segmentation; motion estimation.
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Jaume Garcia, Joel Barajas, Francesc Carreras, Sandra Pujades, & Petia Radeva. (2005). "An intuitive validation technique to compare local versus global tagged MRI analysis " In Computers In Cardiology (Vol. 32, 29–32).
Abstract: Myocardium appears as a uniform tissue that seen in convectional Magnetic Resonance Images (MRI) shows just the contractile part of its movement. MR Tagging is a unique imaging technique that prints a grid over the tissue which moves according to the underlying movement of the myocardium revealing the true deformation of the cardiac muscle. Optical flow techniques based on spectral information estimate tissue displacement by analyzing information encoded in the phase maps which can be obtained using, local (Gabor) and global (HARP) methods. In this paper we compare both in synthetic and real Tagged MR sequences. We conclude that local method is slightly more accurate than the global one. On the other hand, global method is more efficient as it is much faster and less parameters have to be taken into account
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Jaume Garcia, Francesc Carreras, Sandra Pujades, & Debora Gil. (2008). "Regional motion patterns for the Left Ventricle function assessment " In Proc. 19th Int. Conf. Pattern Recognition ICPR 2008 (pp. 1–4).
Abstract: Regional scores (e.g. strain, perfusion) of the Left Ventricle (LV) functionality are playing an increasing role in the diagnosis of cardiac diseases. A main limitation is the lack of normality models for complementary scores oriented to assessment of the LV integrity. This paper introduces an original framework based on a parametrization of the LV domain, which allows comparison across subjects of local physiological measures of different nature. We compute regional normality patterns in a feature space characterizing the LV function. We show the consistency of the model for the regional motion on healthy and hypokinetic pathological cases
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Jaume Garcia, Debora Gil, Sandra Pujades, & Francesc Carreras. (2008). "Valoracion de la Funcion del Ventriculo Izquierdo mediante Modelos Regionales Hiperparametricos " . Revista Española de Cardiologia, 61(3), 79.
Abstract: La mayoría de la enfermedades cardiovasculares afectan a las propiedades contráctiles de la banda ventricular helicoidal. Esto se refleja en una variación del comportamiento normal de la función ventricular. Parámetros locales tales como los strains, o la deformación experimentada por el tejido, son indicadores capaces de detectar anomalías funcionales en territorios específicos. A menudo, dichos parámetros son considerados de forma separada. En este trabajo presentamos un marco computacional (el Dominio Paramétrico Normalizado, DPN) que permite integrarlos en hiperparámetros funcionales y estudiar sus rangos de normalidad. Dichos rangos permiten valorar de forma objetiva la función regional de cualquier nuevo paciente. Para ello, consideramos secuencias de resonancia magnética etiquetada a nivel basal, medio y apical. Los hiperparámetros se obtienen a partir del movimiento intramural del VI estimado mediante el método Harmonic Phase Flow. El DPN se define a partir de en una parametrización del Ventrículo Izquierdo (VI) en sus coordenadas radiales y circunferencial basada en criterios anatómicos. El paso de los hiperparámetros al DPN hace posible la comparación entre distintos pacientes. Los rangos de normalidad se definen mediante análisis estadístico de valores de voluntarios sanos en 45 regiones del DPN a lo largo de 9 fases sistólicas. Se ha usado un conjunto de 19 (14 H; E: 30.7±7.5) voluntarios sanos para crear los patrones de normalidad y se han validado usando 2 controles sanos y 3 pacientes afectados de contractilidad global reducida. Para los controles los resultados regionales se han ajustado dentro de la normalidad, mientras que para los pacientes se han obtenido valores anormales en las zonas descritas, localizando y cuantificando así el diagnóstico empírico.
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Jaume Garcia, Debora Gil, Sandra Pujades, & Francesc Carreras. (2008). "A Variational Framework for Assessment of the Left Ventricle Motion " . International Journal Mathematical Modelling of Natural Phenomena, 3(6), 76–100.
Abstract: Impairment of left ventricular contractility due to cardiovascular diseases is reflected in left ventricle (LV) motion patterns. An abnormal change of torsion or long axis shortening LV values can help with the diagnosis and follow-up of LV dysfunction. Tagged Magnetic Resonance (TMR) is a widely spread medical imaging modality that allows estimation of the myocardial tissue local deformation. In this work, we introduce a novel variational framework for extracting the left ventricle dynamics from TMR sequences. A bi-dimensional representation space of TMR images given by Gabor filter banks is defined. Tracking of the phases of the Gabor response is combined using a variational framework which regularizes the deformation field just at areas where the Gabor amplitude drops, while restoring the underlying motion otherwise. The clinical applicability of the proposed method is illustrated by extracting normality models of the ventricular torsion from 19 healthy subjects.
Keywords: Key words: Left Ventricle Dynamics, Ventricular Torsion, Tagged Magnetic Resonance, Motion Tracking, Variational Framework, Gabor Transform.
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