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Frederic Sampedro; Anna Domenech; Sergio Escalera |
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Obtaining quantitative global tumoral state indicators based on whole-body PET/CT scans: A breast cancer case study |
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Journal Article |
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2014 |
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Nuclear Medicine Communications |
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NMC |
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35 |
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4 |
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362-371 |
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Abstract |
Objectives: In this work we address the need for the computation of quantitative global tumoral state indicators from oncological whole-body PET/computed tomography scans. The combination of such indicators with other oncological information such as tumor markers or biopsy results would prove useful in oncological decision-making scenarios.
Materials and methods: From an ordering of 100 breast cancer patients on the basis of oncological state through visual analysis by a consensus of nuclear medicine specialists, a set of numerical indicators computed from image analysis of the PET/computed tomography scan is presented, which attempts to summarize a patient’s oncological state in a quantitative manner taking into consideration the total tumor volume, aggressiveness, and spread.
Results: Results obtained by comparative analysis of the proposed indicators with respect to the experts’ evaluation show up to 87% Pearson’s correlation coefficient when providing expert-guided PET metabolic tumor volume segmentation and 64% correlation when using completely automatic image analysis techniques.
Conclusion: Global quantitative tumor information obtained by whole-body PET/CT image analysis can prove useful in clinical nuclear medicine settings and oncological decision-making scenarios. The completely automatic computation of such indicators would improve its impact as time efficiency and specialist independence would be achieved. |
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HuPBA;MILAB |
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SDE2014a |
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2444 |
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David Rotger; Misael Rosales; Jaume Garcia; Oriol Pujol ; Josefina Mauri; Petia Radeva |
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Active Vessel: A New Multimedia Workstation for Intravascular Ultrasound and Angiography Fusion |
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2003 |
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Computers in Cardiology |
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30 |
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65-68 |
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AcriveVessel is a new multimedia workstation which enables the visualization, acquisition and handling of both image modalities, on- and ofline. It enables DICOM v3.0 decompression and browsing, video acquisition,repmduction and storage for IntraVascular UltraSound (IVUS) and angiograms with their corresponding ECG,automatic catheter segmentation in angiography images (using fast marching algorithm). BSpline models definition for vessel layers on IVUS images sequence and an extensively validated tool to fuse information. This approach defines the correspondence of every IVUS image with its correspondent point in the angiogram and viceversa. The 3 0 reconstruction of the NUS catheterhessel enables real distance measurements as well as threedimensional visualization showing vessel tortuosity in the space. |
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IAM;MILAB;HuPBA |
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IAM @ iam @ RRG2003 |
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1647 |
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Oriol Pujol; Debora Gil; Petia Radeva |
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Fundamentals of Stop and Go active models |
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2005 |
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Image and Vision Computing |
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23 |
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8 |
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681-691 |
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Deformable models; Geodesic snakes; Region-based segmentation |
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An efficient snake formulation should conform to the idea of picking the smoothest curve among all the shapes approximating an object of interest. In current geodesic snakes, the regularizing curvature also affects the convergence stage, hindering the latter at concave regions. In the present work, we make use of characteristic functions to define a novel geodesic formulation that decouples regularity and convergence. This term decoupling endows the snake with higher adaptability to non-convex shapes. Convergence is ensured by splitting the definition of the external force into an attractive vector field and a repulsive one. In our paper, we propose to use likelihood maps as approximation of characteristic functions of object appearance. The better efficiency and accuracy of our decoupled scheme are illustrated in the particular case of feature space-based segmentation. |
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Butterworth-Heinemann |
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Newton, MA, USA |
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0262-8856 |
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IAM @ iam @ PGR2005 |
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1629 |
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O. Rodriguez; J. Mauri; E Fernandez-Nofrerias; A. Tovar; R. Villuendas; V. Valle; Oriol Pujol; Petia Radeva |
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Analisis de texturas mediante la modificacion de un modelo binario local para la segmentacion automatica de secuencias de ecografia intracoronaria |
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2003 |
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Revista Española de Cardiologia (IF: 0.959), 56(2), Congreso de las Enfermedades Cardiovasculares |
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Sevilla (Spain) |
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BCNPCL @ bcnpcl @ RMF2003f |
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413 |
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O. Rodriguez-Leor; Carlo Gatta; E Fernandez-Nofrerias; Oriol Pujol; Neus Salvatella; C. Bosch; H. Tizon; Petia Radeva; J. Mauri |
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Computationally Efficient Image-based IVUS Pullbacks Gating |
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2008 |
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European Heart Journal, ESC Supplement, Munich, 2008, p. 775 |
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MILAB;HuPBA |
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BCNPCL @ bcnpcl @ RGF2008 |
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1036 |
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