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Frederic Sampedro; Anna Domenech; Sergio Escalera; Ignasi Carrio |
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Title |
Deriving global quantitative tumor response parameters from 18F-FDG PET-CT scans in patients with non-Hodgkins lymphoma |
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Journal Article |
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2015 |
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Nuclear Medicine Communications |
Abbreviated Journal |
NMC |
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36 |
Issue |
4 |
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328-333 |
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Abstract |
OBJECTIVES:
The aim of the study was to address the need for quantifying the global cancer time evolution magnitude from a pair of time-consecutive positron emission tomography-computed tomography (PET-CT) scans. In particular, we focus on the computation of indicators using image-processing techniques that seek to model non-Hodgkin's lymphoma (NHL) progression or response severity.
MATERIALS AND METHODS:
A total of 89 pairs of time-consecutive PET-CT scans from NHL patients were stored in a nuclear medicine station for subsequent analysis. These were classified by a consensus of nuclear medicine physicians into progressions, partial responses, mixed responses, complete responses, and relapses. The cases of each group were ordered by magnitude following visual analysis. Thereafter, a set of quantitative indicators designed to model the cancer evolution magnitude within each group were computed using semiautomatic and automatic image-processing techniques. Performance evaluation of the proposed indicators was measured by a correlation analysis with the expert-based visual analysis.
RESULTS:
The set of proposed indicators achieved Pearson's correlation results in each group with respect to the expert-based visual analysis: 80.2% in progressions, 77.1% in partial response, 68.3% in mixed response, 88.5% in complete response, and 100% in relapse. In the progression and mixed response groups, the proposed indicators outperformed the common indicators used in clinical practice [changes in metabolic tumor volume, mean, maximum, peak standardized uptake value (SUV mean, SUV max, SUV peak), and total lesion glycolysis] by more than 40%.
CONCLUSION:
Computing global indicators of NHL response using PET-CT imaging techniques offers a strong correlation with the associated expert-based visual analysis, motivating the future incorporation of such quantitative and highly observer-independent indicators in oncological decision making or treatment response evaluation scenarios. |
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HuPBA;MILAB |
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Admin @ si @ SDE2015 |
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2605 |
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Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio |
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Title |
A computational framework for cancer response assessment based on oncological PET-CT scans |
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Journal Article |
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2014 |
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Computers in Biology and Medicine |
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CBM |
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55 |
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92–99 |
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Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis |
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In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks. |
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HuPBA;MILAB |
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Admin @ si @ SED2014 |
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2606 |
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Andres Traumann; Gholamreza Anbarjafari; Sergio Escalera |
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Title |
Accurate 3D Measurement Using Optical Depth Information |
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2015 |
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Electronic Letters |
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EL |
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51 |
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18 |
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1420-1422 |
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A novel three-dimensional measurement technique is proposed. The methodology consists in mapping from the screen coordinates reported by the optical camera to the real world, and integrating distance gradients from the beginning to the end point, while also minimising the error through fitting pixel locations to a smooth curve. The results demonstrate accuracy of less than half a centimetre using Microsoft Kinect II. |
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HuPBA;MILAB |
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Admin @ si @ TAE2015 |
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2647 |
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Ciprian Corneanu; Marc Oliu; Jeffrey F. Cohn; Sergio Escalera |
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Survey on RGB, 3D, Thermal, and Multimodal Approaches for Facial Expression Recognition: History |
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2016 |
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IEEE Transactions on Pattern Analysis and Machine Intelligence |
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TPAMI |
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28 |
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8 |
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1548-1568 |
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Facial expression; affect; emotion recognition; RGB; 3D; thermal; multimodal |
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Facial expressions are an important way through which humans interact socially. Building a system capable of automatically recognizing facial expressions from images and video has been an intense field of study in recent years. Interpreting such expressions remains challenging and much research is needed about the way they relate to human affect. This paper presents a general overview of automatic RGB, 3D, thermal and multimodal facial expression analysis. We define a new taxonomy for the field, encompassing all steps from face detection to facial expression recognition, and describe and classify the state of the art methods accordingly. We also present the important datasets and the bench-marking of most influential methods. We conclude with a general discussion about trends, important questions and future lines of research. |
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HuPBA;MILAB; |
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Admin @ si @ COC2016 |
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2718 |
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Antonio Hernandez; Sergio Escalera; Stan Sclaroff |
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Title |
Poselet-basedContextual Rescoring for Human Pose Estimation via Pictorial Structures |
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Journal Article |
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2016 |
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International Journal of Computer Vision |
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IJCV |
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118 |
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1 |
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49–64 |
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Contextual rescoring; Poselets; Human pose estimation |
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In this paper we propose a contextual rescoring method for predicting the position of body parts in a human pose estimation framework. A set of poselets is incorporated in the model, and their detections are used to extract spatial and score-related features relative to other body part hypotheses. A method is proposed for the automatic discovery of a compact subset of poselets that covers the different poses in a set of validation images while maximizing precision. A rescoring mechanism is defined as a set-based boosting classifier that computes a new score for each body joint detection, given its relationship to detections of other body joints and mid-level parts in the image. This new score is incorporated in the pictorial structure model as an additional unary potential, following the recent work of Pishchulin et al. Experiments on two benchmarks show comparable results to Pishchulin et al. while reducing the size of the mid-level representation by an order of magnitude, reducing the execution time by 68 % accordingly. |
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Springer US |
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0920-5691 |
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HuPBA;MILAB; |
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Admin @ si @ HES2016 |
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2719 |
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