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	Author	Carles Sanchez; Jorge Bernal; F. Javier Sanchez; Antoni Rosell; Marta Diez-Ferrer; Debora Gil
	Title	Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy			Type	Journal Article
	Year	2015	Publication	International Journal of Computer Assisted Radiology and Surgery	Abbreviated Journal	IJCAR
	Volume	10	Issue	6	Pages	935-945
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; MV; 600.075			Approved	no
	Call Number	Admin @ si @ SBS2015a			Serial	2611
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	Author	Carles Sanchez; Jorge Bernal; F. Javier Sanchez; Marta Diez-Ferrer; Antoni Rosell; Debora Gil
	Title	Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy			Type	Conference Article
	Year	2015	Publication	6th International Conference on Information Processing in Computer-Assisted Interventions IPCAI2015	Abbreviated Journal
	Volume	10	Issue	6	Pages	935-945
	Keywords
	Abstract	PURPOSE: Lack of objective measurement of tracheal obstruction degree has a negative impact on the chosen treatment prone to lead to unnecessary repeated explorations and other scanners. Accurate computation of tracheal stenosis in videobronchoscopy would constitute a breakthrough for this noninvasive technique and a reduction in operation cost for the public health service. METHODS: Stenosis calculation is based on the comparison of the region delimited by the lumen in an obstructed frame and the region delimited by the first visible ring in a healthy frame. We propose a parametric strategy for the extraction of lumen and tracheal ring regions based on models of their geometry and appearance that guide a deformable model. To ensure a systematic applicability, we present a statistical framework to choose optimal parametric values and a strategy to choose the frames that minimize the impact of scope optical distortion. RESULTS: Our method has been tested in 40 cases covering different stenosed tracheas. Experiments report a non- clinically relevant [Formula: see text] of discrepancy in the calculated stenotic area and a computational time allowing online implementation in the operating room. CONCLUSIONS: Our methodology allows reliable measurements of airway narrowing in the operating room. To fully assess its clinical impact, a prospective clinical trial should be done.
	Address	Barcelona; Spain; June 2015
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	IPCAI
	Notes	IAM; MV; 600.075			Approved	no
	Call Number	Admin @ si @ SBS2015b			Serial	2613
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	Author	Carles Sanchez; Miguel Viñas; Coen Antens; Agnes Borras; Debora Gil
	Title	Back to Front Architecture for Diagnosis as a Service			Type	Conference Article
	Year	2018	Publication	20th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing	Abbreviated Journal
	Volume		Issue		Pages	343-346
	Keywords
	Abstract	Software as a Service (SaaS) is a cloud computing model in which a provider hosts applications in a server that customers use via internet. Since SaaS does not require to install applications on customers' own computers, it allows the use by multiple users of highly specialized software without extra expenses for hardware acquisition or licensing. A SaaS tailored for clinical needs not only would alleviate licensing costs, but also would facilitate easy access to new methods for diagnosis assistance. This paper presents a SaaS client-server architecture for Diagnosis as a Service (DaaS). The server is based on docker technology in order to allow execution of softwares implemented in different languages with the highest portability and scalability. The client is a content management system allowing the design of websites with multimedia content and interactive visualization of results allowing user editing. We explain a usage case that uses our DaaS as crowdsourcing platform in a multicentric pilot study carried out to evaluate the clinical benefits of a software for assessment of central airway obstruction.
	Address	Timisoara; Rumania; September 2018
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	SYNASC
	Notes	IAM; 600.145			Approved	no
	Call Number	Admin @ si @ SVA2018			Serial	3360
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	Author	Carles Sanchez; Oriol Ramos Terrades; Patricia Marquez; Enric Marti; J.Roncaries; Debora Gil
	Title	Automatic evaluation of practices in Moodle for Self Learning in Engineering			Type	Journal
	Year	2015	Publication	Journal of Technology and Science Education	Abbreviated Journal	JOTSE
	Volume	5	Issue	2	Pages	97-106
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; DAG; 600.075; 600.077			Approved	no
	Call Number	Admin @ si @ SRM2015			Serial	2610
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	Author	Carles Sanchez; Oriol Ramos Terrades; Patricia Marquez; Enric Marti; Jaume Rocarias; Debora Gil
	Title	Evaluación automática de prácticas en Moodle para el aprendizaje autónomo en Ingenierías			Type	Miscellaneous
	Year	2014	Publication	8th International Congress on University Teaching and Innovation	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract
	Address	Tarragona; juliol 2014
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CIDUI
	Notes	IAM; 600.075;DAG			Approved	no
	Call Number	Admin @ si @ SRM2014			Serial	2458
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	Author	Carles Sanchez;F. Javier Sanchez; Antoni Rosell; Debora Gil
	Title	An illumination model of the trachea appearance in videobronchoscopy images			Type	Book Chapter
	Year	2012	Publication	Image Analysis and Recognition	Abbreviated Journal	LNCS
	Volume	7325	Issue		Pages	313-320
	Keywords	Bronchoscopy, tracheal ring, stenosis assesment, trachea appearance model, segmentation
	Abstract	Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways. This imaging modality provides realistic images and allows non-invasive minimal intervention procedures. Tracheal procedures are routinary interventions that require assessment of the percentage of obstructed pathway for injury (stenosis) detection. Visual assessment in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error. This paper introduces an automatic method for the estimation of steneosed trachea percentage reduction in videobronchoscopic images. We look for tracheal rings , whose deformation determines the degree of obstruction. For ring extraction , we present a ring detector based on an illumination and appearance model. This model allows us to parametrise the ring detection. Finally, we can infer optimal estimation parameters for any video resolution.
	Address	Aveiro, Portugal
	Corporate Author				Thesis
	Publisher	Springer Berlin Heidelberg	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title	Lecture Notes in Computer Science	Abbreviated Series Title	LNCS
	Series Volume		Series Issue		Edition
	ISSN	0302-9743	ISBN	978-3-642-31297-7	Medium
	Area	800	Expedition		Conference	ICIAR
	Notes	MV;IAM			Approved	no
	Call Number	IAM @ iam @ SSR2012			Serial	1898
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	Author	Cristina Cañero; Petia Radeva; Oriol Pujol; Ricardo Toledo; Debora Gil; J. Saludes; Juan J. Villanueva; B. Garcia del Blanco; J. Mauri; E. Fernandez-Nofrerias; J.A. Gomez-Hospital; E. Iraculis; J. Comin; C. Quiles; F. Jara; A. Cequier; E. Esplugas
	Title	Optimal Stent Implantation: Three-dimensional Evaluation of the Mutual Position of Stent and Vessel via Intracoronary Ecography			Type	Conference Article
	Year	1999	Publication	Proceedings of International Conference on Computer in Cardiology (CIC´99)	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	We present a new automatic technique to visualize and quantify the mutual position between the stent and the vessel wall by considering their three-dimensional reconstruction. Two deformable generalized cylinders adapt to the image features in all IVUS planes corresponding to the vessel wall and the stent in order to reconstruct the boundaries of the stent and the vessel in space. The image features that characterize the stent and the vessel wall are determined in terms of edge and ridge image detectors taking into account the gray level of the image pixels. We show that the 30 reconstruction by deformable cylinders is accurate and robust due to the spatial data coherence in the considered volumetric IVUS image. The main clinic utility of the stent and vessel reconstruction by deformable’ cylinders consists of its possibility to visualize and to assess the optimal stent introduction.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	MILAB; RV; IAM; ADAS; HuPBA			Approved	no
	Call Number	IAM @ iam @ CRP1999a			Serial	1491
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	Author	Cristina Cañero; Petia Radeva; Oriol Pujol; Ricardo Toledo; Debora Gil; J. Saludes; Juan J. Villanueva; B. Garcia del Blanco; Josefina Mauri; Eduard Fernandez-Nofrerias; J.A. Gomez-Hospital; E. Iraculis; J. Comin; C. Quiles; F. Jara; A. Cequier; E.Esplugas
	Title	Three-dimensional reconstruction and quantification of the coronary tree using intravascular ultrasound images			Type	Conference Article
	Year	1999	Publication	Proceedings of International Conference on Computer in Cardiology (CIC´99)	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	In this paper we propose a new Computer Vision technique to reconstruct the vascular wall in space using a deformable model-based technique and compounding methods, based in biplane angiography and intravascular ultrasound data jicsion. It is also proposed a generalpurpose three-dimensional guided interpolation method. The three dimensional centerline of the vessel is reconstructed from geometrically corrected biplane angiographies using automatic segmentation methods and snakes. The IVUS image planes are located in the threedimensional space and correctly oriented. A led interpolation method based in B-SurJaces and snakes isused to fill the gaps among image planes
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	CINC99
	Notes	MILAB;RV;IAM;ADAS;HuPBA			Approved	no
	Call Number	IAM @ iam @ CRP1999b			Serial	1492
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	Author	David Castells; Vinh Ngo; Juan Borrego-Carazo; Marc Codina; Carles Sanchez; Debora Gil; Jordi Carrabina
	Title	A Survey of FPGA-Based Vision Systems for Autonomous Cars			Type	Journal Article
	Year	2022	Publication	IEEE Access	Abbreviated Journal	ACESS
	Volume	10	Issue		Pages	132525-132563
	Keywords	Autonomous automobile; Computer vision; field programmable gate arrays; reconfigurable architectures
	Abstract	On the road to making self-driving cars a reality, academic and industrial researchers are working hard to continue to increase safety while meeting technical and regulatory constraints Understanding the surrounding environment is a fundamental task in self-driving cars. It requires combining complex computer vision algorithms. Although state-of-the-art algorithms achieve good accuracy, their implementations often require powerful computing platforms with high power consumption. In some cases, the processing speed does not meet real-time constraints. FPGA platforms are often used to implement a category of latency-critical algorithms that demand maximum performance and energy efficiency. Since self-driving car computer vision functions fall into this category, one could expect to see a wide adoption of FPGAs in autonomous cars. In this paper, we survey the computer vision FPGA-based works from the literature targeting automotive applications over the last decade. Based on the survey, we identify the strengths and weaknesses of FPGAs in this domain and future research opportunities and challenges.
	Address	16 December 2022
	Corporate Author				Thesis
	Publisher	IEEE	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; 600.166			Approved	no
	Call Number	Admin @ si @ CNB2022			Serial	3760
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	Author	David Roche; Debora Gil; Jesus Giraldo
	Title	Using statistical inference for designing termination conditions ensuring convergence of Evolutionary Algorithms			Type	Conference Article
	Year	2011	Publication	11th European Conference on Artificial Life	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	A main challenge in Evolutionary Algorithms (EAs) is determining a termination condition ensuring stabilization close to the optimum in real-world applications. Although for known test functions distribution-based quantities are good candidates (as far as suitable parameters are used), in real-world problems an open question still remains unsolved. How can we estimate an upper-bound for the termination condition value ensuring a given accuracy for the (unknown) EA solution? We claim that the termination problem would be fully solved if we defined a quantity (depending only on the EA output) behaving like the solution accuracy. The open question would be, then, satisfactorily answered if we had a model relating both quantities, since accuracy could be predicted from the alternative quantity. We present a statistical inference framework addressing two topics: checking the correlation between the two quantities and defining a regression model for predicting (at a given confidence level) accuracy values from the EA output.
	Address	Paris, France
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	ECAL
	Notes	IAM;			Approved	no
	Call Number	IAM @ iam @ RGG2011b			Serial	1678
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	Author	David Roche; Debora Gil; Jesus Giraldo
	Title	Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models?			Type	Book Chapter
	Year	2014	Publication	G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology	Abbreviated Journal
	Volume	796	Issue	3	Pages	159-181
	Keywords	β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model
	Abstract	Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.
	Address
	Corporate Author				Thesis
	Publisher	Springer Netherlands	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0065-2598	ISBN	978-94-007-7422-3	Medium
	Area		Expedition		Conference
	Notes	IAM; 600.075			Approved	no
	Call Number	IAM @ iam @ RGG2014			Serial	2197
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	Author	David Roche; Debora Gil; Jesus Giraldo
	Title	Detecting loss of diversity for an efficient termination of EAs			Type	Conference Article
	Year	2013	Publication	15th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing	Abbreviated Journal
	Volume		Issue		Pages	561 - 566
	Keywords	EA termination; EA population diversity; EA steady state
	Abstract	Termination of Evolutionary Algorithms (EA) at its steady state so that useless iterations are not performed is a main point for its efficient application to black-box problems. Many EA algorithms evolve while there is still diversity in their population and, thus, they could be terminated by analyzing the behavior some measures of EA population diversity. This paper presents a numeric approximation to steady states that can be used to detect the moment EA population has lost its diversity for EA termination. Our condition has been applied to 3 EA paradigms based on diversity and a selection of functions covering the properties most relevant for EA convergence. Experiments show that our condition works regardless of the search space dimension and function landscape.
	Address	Timisoara; Rumania;
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN	978-1-4799-3035-7	Medium
	Area		Expedition		Conference	SYNASC
	Notes	IAM; 600.044; 600.060; 605.203			Approved	no
	Call Number	Admin @ si @ RGG2013c			Serial	2299
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	Author	David Roche; Debora Gil; Jesus Giraldo
	Title	Mechanistic analysis of the function of agonists and allosteric modulators: Reconciling two-state and operational models			Type	Journal Article
	Year	2013	Publication	British Journal of Pharmacology	Abbreviated Journal	BJP
	Volume	169	Issue	6	Pages	1189-202
	Keywords
	Abstract	Two-state and operational models of both agonism and allosterism are compared to identify and characterize common pharmacological parameters. To account for the receptor-dependent basal response, constitutive receptor activity is considered in the operational models. By arranging two-state models as the fraction of active receptors and operational models as the fractional response relative to the maximum effect of the system, a one-by-one correspondence between parameters is found. The comparative analysis allows a better understanding of complex allosteric interactions. In particular, the inclusion of constitutive receptor activity in the operational model of allosterism allows the characterization of modulators able to lower the basal response of the system; that is, allosteric modulators with negative intrinsic efficacy. Theoretical simulations and overall goodness of fit of the models to simulated data suggest that it is feasible to apply the models to experimental data and constitute one step forward in receptor theory formalism.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; 600.044; 605.203			Approved	no
	Call Number	IAM @ iam @ RGG2013b			Serial	2195
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	Author	David Roche; Debora Gil; Jesus Giraldo
	Title	Multiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism,			Type	Journal Article
	Year	2013	Publication	Drug Discovery Today	Abbreviated Journal	DDT
	Volume	18	Issue	7-8	Pages	365-371
	Keywords
	Abstract	The operational model of agonism assumes that the maximum effect a particular receptor system can achieve (the Em parameter) is fixed. Em estimates are above but close to the asymptotic maximum effects of endogenous agonists. The concept of Em is contradicted by superagonists and those positive allosteric modulators that significantly increase the maximum effect of endogenous agonists. An extension of the operational model is proposed that assumes that the Em parameter does not necessarily have a single value for a receptor system but has multiple values associated to multiple active receptor conformations. The model provides a mechanistic link between active receptor conformation and agonist efficacy, which can be useful for the analysis of agonist response under different receptor scenarios.
	Address
	Corporate Author				Thesis
	Publisher	Elsevier	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	IAM; 600.057; 600.054			Approved	no
	Call Number	IAM @ iam @ RGG2013a			Serial	2190
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	Author	David Roche; Debora Gil; Jesus Giraldo
	Title	Assessing agonist efficacy in an uncertain Em world			Type	Conference Article
	Year	2012	Publication	40th Keystone Symposia on mollecular and celular biology	Abbreviated Journal
	Volume		Issue		Pages	79
	Keywords
	Abstract	The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates. In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.
	Address	Fairmont Banff Springs, Banff, Alberta, Canada
	Corporate Author	Keystone Symposia			Thesis
	Publisher	Keystone Symposia	Place of Publication		Editor	A. Christopoulus and M. Bouvier
	Language	english	Summary Language	english	Original Title
	Series Editor	Keystone Symposia	Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference	KSMCB
	Notes	IAM			Approved	no
	Call Number	IAM @ iam @ RGG2012			Serial	1855
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